Información del artículo
Summary
Objective
We aim, with this collection of the last publications about this subject, to promote to the angiologists and vascular surgeons their continuous formation.
DevelopmentThe biochemistry, formation and regulation, actions, possible uses and clinical relevance of the nitric oxide molecule, which is synthesized by most mammal cells and has both systemic and local vasoactivity, are described in this work.
ConclusionAs It has been increasingly demonstrated, the success of nitric oxide in many areas of medicine, especially in the field of vascular medicine, allows us to suggest an endogenous-response manipulatory therapy for this molecule aiming better results on our field of work.
Key words:
Atherosclerosis
Endogenous response
Endotelium
L-arginine
Nitric oxide
Vasodilation
Resumen
Objetivo
El objetivo es promover la formación continua de los profesionales de la cirugía vascular y angiología mediante una recopilación de las últimas publicaciones sobre el tema.
DesarrolloAbordamos la bioquímica, formación, regulación, acciones, posibles usos y la relevancia clínica de la molécula de óxido nítrico, compuesto sintetizado por la mayoría de las células de los mamíferos y que presenta efectos vasomotores locales y sistémicos de importancia para la mayoría de las patologías y tratamientos del ámbito de la cirugía vascular y de la angiología.
ConclusiónSe han identificado las diversas áreas de actuación para su uso y se ha sugerido la terapia manipuladora de la respuesta endógena del compuesto mencionado, con el fin de obtener mejores resultados en los ámbitos de la medicina citados anteriormente.
Palabras clave:
Aterosclerosis
Endotelio
L-arginina
Óxido nítrico
Respuesta endógena
Vasodilatation
Resumo
Objectivo
Objetiva-se promover a formação continuada dos profissionais da cirurgia vascular e angiologia com um apanhado das últimas publicações sobre o assunto proposto.
DesenvolvimentoAbordamos a bioquímica, formçõao, regulação, as acções, possíveis usos e relevância clínica da molécula de óxido nítrico, composto sintetizado pela maioria das células mamíferas e que tem efeitos vasomotores locais e sisté-micos de relevância para a maioria das patologias e tratamentos no â;mbito da cirurgia vascular e da angiologia.
ConclusãoSão identificadas as diversas áreas de actuação para seu uso e é sugerido a terapia manipulatória da resposta endógena do referido composto para melhores resultados nos campos da medicina supracitados.
Palavras clave:
Aterosclerose
Endotélio
L-arginina
Óxido nítrico
Resposta endógena
Vasodilatacao
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