Background and aim: Liver adenomas are benign tumors of epithelial origin, infrequent, predominantly in women of childbearing age, and associated with the use of oral contraceptives (ACO), and comorbidities such as metabolic syndrome, obesity, diabetes, etc. They are usually asymptomatic, of incidental diagnosis, associated with complications such as bleeding and malignant transformation to hepatocarcinoma, which has been related to their histological characteristics. Aim: To determine the clinical, demographic, radiological and histological characteristics of a series of liver adenomas in a reference hospital.
Material and methods: Observational, cross-sectional, retrolective study, carried out in the period 2009-2019.
Results: In this study female sex predominated in 61.1% and an average age of 34.3 years. The most frequent comorbidities were overweight and dyslipidemia with 38.9% and 27.8% respectively. Most were single lesions, in the right liver lobe, less than 5cm in 55.6%. They were associated with ACO consumption in 27.8%. Adenoma subtypes were identified in 54% of cases, with inflammatory adenomas found in 66.6%, beta-catenin adenomas activated in 16.6% and inactivated adenomas in 16.6%, with evidence of complications such as hepatocarcinoma foci, hemorrhages and abscess.
Conclusions: Liver adenomas are rare tumors. They occurred predominantly in women, as single lesions smaller than 5cm, associated with comorbidities and use of OAC. Complications such as hemorrhages, abscesses, and transformation to hepatocellular carcinoma were evident, which were associated with the histological subtype of adenomas.
Conflicts of interest: The authors have no conflicts of interest to declare.
