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Annals of Hepatology
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Vol. 24. Núm. S1.
Abstracts of the 2021 Annual meeting of the ALEH (Asociación Latinoamericana para el Estudio del Hígado)
(septiembre 2021)
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Vol. 24. Núm. S1.
Abstracts of the 2021 Annual meeting of the ALEH (Asociación Latinoamericana para el Estudio del Hígado)
(septiembre 2021)
Open Access
O-17 Are macroeconomic and health expenditure indicators correlated with the capacity for liver transplantation in Latin American Countries? THE ALEH Special Interest Group, international Survey 2020
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Rodrigo Zapata1, Graciela Castro2, Josefina Pages3, Fernando Cairo4, Oscar Imventarza5, Alejandra Villamil6, Paulo Bittencourt7, Leonardo Schiavon8, J.R. Alfeu de Medeiros Fleck9, Ricardo Villarroel10, Oscar Varas11, Juan Carlos Restrepo12, Adriana Varon13, Daniela Hernandez14, Pablo Coste15, Marcia Samada16, Antonio Enamorado17, Chong Ricardo18, Byron Abad19, Alvaro Urzúa20..., Rodrigo Wolff21, Mario Uribe22, Regina Ligorrea23, Edgard Aguilera24, Eira Cerda25, Sergio Lopez26, Marcos Girala27, Martin Padilla28, Marlene Perez29, Victoria Mainardi30, Solange Gerona31Ver más
1 Coordinator, ALEH Liver Transplant Sig. Unidad de Transplante, Clinica Alemana / Facultad de Medicina, Universidad del Desarrollo, Santiago, Chile
2 Co-coordinator, ALEH Liver Transplant Sig. Instituto Nacional de Ciencias Medicas y Nutrición Salvador Zubiran y Hospital Medica Sur, Ciudad de Mexico, Mexico
3 Liver Transplant Unit, Hospital Universitario Austral, Universidad de Buenos Aires, Buenos Aires, Argentina
4 Liver Transplant Unit, Hospital el Cruce, Hospital Britanico, Buenos Aires, Argentina
5 Liver Transplant Unit, Hospital Argerich, Hospital Garrahan, Stalyc Representative, Buenos Aires, Argentina
6 Liver Transplant Unit, Hospital Italiano de Buenos Aires, Argentina
7 Liver Unit, Hospital Portugues de Salvador, Bahi, Brazil
8 Universidad Federal de Santa Catarin, Florianopolis, Santa Catarina, Brazil
9 Liver Transplant Unit, Hospital Moinhos de Vento, Irmandade de Santa Casa de Misericordia de Porto Alegre, Porto Alegre, Brazil
10 Hospital San Juan de Dios, Santa Cruz de la Sierra, Bolivia
11 Centro de Enfermedades Digestivas Varas Castrillo, Tarija, Bolivia
12 Liver Transplant Unit, Hospital Pablo Tobon Uribe, Medellin, Colombia
13 Liver Unit, Fundación Cardioinfantil, Bogota, Colombia
14 Hospital Mexico, La Oruca, San Jose, Costa Rica
15 Hospital Rafael Angel Calderon Guardia, San Jose, Costa Rica
16 Centro de Investigaciones Medico-Quirurgicas, La Habana, Cuba
17 Programa de Trasplantes, La Habana, Cuba
18 Liver Transplant Unit, Hospital de Especialidades Carlos Andrade Marin, Quito, Ecuador
19 Transplant Coordinator, Hospital de Especialidades Arlos Andrade Marin, Quito, Ecuador
20 Liver Transplant Unit, Hospital Clinico, Universidad de Chile y Clinica Santa Maria, Santiago, Chile
21 Liver Transplant Unit, P. Universidad Catolica de Chile, Santiago, Chile
22 Liver Transplant Unit, Hospital Salvador, Hospital Calvo Mackena y Clinica Las Condes, Stalyc Representative, Santiago, Chile
23 Hospital San Juan de Dios, Ciudad de Guatemala, Guatemala
24 Hospital Clinica Viera, Tegucigalpa, Honduras
25 Unidad de Trasplante Hepatico, Hospital Central Militar, Ciudad de Mexico, Mexico
26 Hospital Escuale Dr. Roberto Calderon, Managua, Nicaragua
27 Universidad Nacional de Asunción, Asuncion, Paraguay
28 Department of Transplantation, Hospital Nacional Guillermo Almenara y Universidad Nacional Mayor de San Marcos, Lima, Perú
29 Liver Transplant Unit, Hospital General de la Plaza de la Salud, Santo Domingo, Republica Dominicana
30 Liver Transplant Unit, Hospital Central de las Fuerzas Armadas, Montevideo, Uruguay
31 Liver Transplant Unit, Hospital de Clinicas y Hospital Central de las Fuerzas Armadas, Montevideo, Uruguay
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Table 1. Summary of demographics, macroeconomical indicators and LT practices in LA (LT: Liver Transplantation; DDLT: Deceased donor LT; LDLT: Living donor LT; Rates: per million population; GDP: Gross domestic product; pp: per capita; LOS: Length of stay of hospitalization for LT; Pop: Population; Mill: Millions; Dom. Rep.: Dominican Republic; USD: US Dollars; Hosp: Hospitalization)
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Vol. 24. Núm S1

Abstracts of the 2021 Annual meeting of the ALEH (Asociación Latinoamericana para el Estudio del Hígado)

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Introduction

Latin America (LA), is a geographical region with 20 countries homing 652 million people (10% world population), with a huge cultural, economic and developmental diversity. The ALEH (Asociación Latinamericana para el Estudio del Hígado) has driven the formation of special interest groups (SIGs) to enhance the collaboration of health care professionals with common specialized interests in the field of hepatology. The gross domestic product (GDP) is a monetary measure of the market value of all the final goods and services produced in a specific time period by a country. The ratio of GDP to the total population of the region is the per capita GDP (Mean Standard of Living). It is often considered to be the "world's most powerful statistical indicator of national development and progress". On the other hand, Liver transplantation (LT) is considered a very expensive procedure requiring high-cost management with a lifelong immunosuppression, hence a possible barrier to some underdeveloped countries. In the different regions of the USA, there has been shown a strong correlation between GDP per capita and all organ donation rates, except heart donation (1988-2012). In LA countries, there is almost no data on the relation of macroeconomic indicators in relation to the capacity for LT.

Aims

To study the influence of macroeconomic indicators with the LT capacity in LA.

Methods

During 2020, LA countries, were invited to nominate representatives to this SIG and also from the STALYC. Online ZOOM meetings were arranged to discuss a survey of more than 70 questions in relation to different topics in LT including economic indicators of countries, barriers and access to LT. A database with all the information was built in an excel file. Scatter plot graphs were built to evaluate correlation and linear regression equations for different variables.

Results

15 out of 20 countries completed the questionnaire by Jan/2021. During 2019 there were 3,354 DDLT performed in 13 out of the 15 countries (DDLT rate of 5.85 LT/pmp), and 483 LDLT in 7 countries. The mean costs of LT (hospitalization and first month) in our survey was 57,000 USD. After evaluating a few macroeconomic indicators, the higher GDP per capita and the higher health expenditure (as % of GDP) had a good positive correlation with the LT capacity in LA countries (scatter plot). There was no correlation with the gross GDP with LT (DDLT nor LDLT), nor with de number of active LT centers in each country.

Conclusions

Our study shows a positive correlation between economic indicators of prosperity (GDP per capita and health expenditure) and LT rates. Chronic liver diseases are a very common cause of burden of disease in LA, and although LT is a high-cost procedure, it is. a lot less expensive than in other world regions. LA is still composed of countries with huge cultural, economic and developmental diversity and where at least 30% of the population lives in poverty, nevertheless, some countries have been able to perform LT with rates > 5 ppm with excellent results. There is need to improve education and investment in LT as a health priority, being saving life procedure making possible to return a chronic patient to a normal and productive life.

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