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Annals of Hepatology
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Inicio Annals of Hepatology P- 54 HEPATITIS C MICROELIMINATION IN FORMER DRUG USERS
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Vol. 28. Núm. S1.
Abstracts of the 2022 Annual Meeting of the ALEH
(marzo 2023)
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Vol. 28. Núm. S1.
Abstracts of the 2022 Annual Meeting of the ALEH
(marzo 2023)
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P- 54 HEPATITIS C MICROELIMINATION IN FORMER DRUG USERS
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Fernando Gruz1, Maria Gimena Fernandez2, Santiago Gimenez3, Guillermo Dorado4, Maria Laura Martin5, Adrian Farias6, Solange Mizrahi7, Maricel Bellicoso7
1 Liver Disease Unit. Inmunology Buenos Aires, Buenos Aires, Argentina
2 Liver Disease Unit, Churruca-Visca Hospital, Buenos Aires, Argentina
3 Infectious Diseases, Cemar N2, Buenos Aires, Argentina
4 Psychiatry, Rehabilitation Center GENS, Buenos Aires, Argentina
5 Psychology, Rehabilitattion Center Reencuentros, Buenos Aires, Argentina
6 Psychology, Regabilitation Center Gens, Buenos Aires, Argentina
7 Gastroenterologist, Inmunology Buenos Aires, Buenos Aires, Argentina
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Vol. 28. Núm S1

Abstracts of the 2022 Annual Meeting of the ALEH

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Introduction and Objectives

Hepatitis C (HCV) infection is a major health problem around the globe. World Health Organization is committed to eliminating viral hepatitis by 2030. The most pragmatic approach to achieve this objective is to break down national elimination goals into smaller targets for individual population segments (microelimination). HCV prevalence in Argentina is about 0.5% in the general population, but there is no prevalence data in the drug users sub-population in our country. This study aimed to present study are 1) to estimate HCV prevalence among drug users in Argentina 2) and to describe clinical and virological characteristics in this community.

Materials and Methods

Cross-sectional study. Eligible patients (pts) were 18 years of age or older with present or past drug use history. Exclusion criteria were refusal to participate in the study, incapacity to understand the informed consent and severe mental illness. Pts were evaluated by a quick visual qualitative assay to detect HCV antibodies (Montebio®: Sensitivity: 99.8% -Specifity: 99.9%) and they were asked to answer a brief questionnaire to evaluate the presence of other HCV risk factors.

Results

Between March 1st, 2021 and October 30th, 2021, 202 eligible pts were identified. We excluded 4 pts (1 because of acute cocaine intoxication and 3 pts refused to participate). A total of 198 consecutive pts were included. Seven pts (3.5%) had a positive qualitative assay result and were further assessed for liver fibrosis, viral load, genotype and co-infections (table 1). Six out of seven pts (86%) did not know that they had had contact with HCV, 4/7 (57%) had positive viremia and 75% of them received antiviral treatment.

Conclusions

HCV prevalence among drug users is higher than in the general population. Microelimination is a useful tool to approach this global health problem.

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