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Annals of Hepatology
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Inicio Annals of Hepatology P- 69 CHRONIC HEPATITIS B: EPIDEMIOLOGICAL CHARACTERISTICS, EVOLUTION AND PREVAL...
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Vol. 28. Núm. S1.
Abstracts of the 2022 Annual Meeting of the ALEH
(marzo 2023)
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Vol. 28. Núm. S1.
Abstracts of the 2022 Annual Meeting of the ALEH
(marzo 2023)
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P- 69 CHRONIC HEPATITIS B: EPIDEMIOLOGICAL CHARACTERISTICS, EVOLUTION AND PREVALENT PHASES, IN REFERENCE CENTERS IN PARAGUAY
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Mirian Colarte, Marcos Girala, Lorena Martinez, Sebastian Diaz, Jesús Ortiz
Department of Gastroenterology and Digestive Endoscopy, Clinics Hospital, National University of Asunción, San Lorenzo, Paraguay
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Vol. 28. Núm S1

Abstracts of the 2022 Annual Meeting of the ALEH

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Introduction and Objectives

Viral hepatitis is a public health problem worldwide. Approximately 325 million people worldwide were living with chronic hepatitis at the end of 2015: the most prevalent, HBV. There is not much information on the characteristics of patients with chronic hepatitis B in Paraguay. This study aimed to know the characteristics of the population with chronic Hepatitis B who consulted and/or had a follow-up in two hepatology reference centers in the period between 2000 - 2019.

Materials and Methods

Observational, descriptive, retrospective. Excel for data collection. Variables are expressed as frequency, mean and percentages.

Results

12,972 medical records were evaluated, of which 171 (1.3%) had a diagnosis of Chronic Hepatitis B. 127 files were included, and 44 (26%) of the stories did not have enough information for the present analysis. Eighty-two (65%) of the patients were Paraguayan, 44 (35%) of Asian origin, and 1 (0.8%) were African. A liver biopsy was performed on 17% of the patients: 7 were in the cirrhotic stage and 4 had no inflammatory activity. Of the 127 patients studied: 3 (3%) were in Phase 1, 38 (32%) in Phase 2 (82% Western); 61 (51%) in Phase 3 and 16 (14%) in Phase 4 (44% from the far East communities). Thirty (24%) were in the cirrhotic stage; in 20 of these, some manifestation of Portal Hypertension was found, the most frequent being esophageal varices. Three of the 127 (2.4%) were diagnosed with HCC (two of them in the cirrhotic stage: corresponding to 6.7% of this population).

Conclusions

This series contributes to estimating the characteristics of patients with chronic Hepatitis B in Paraguay. Most are indigenous cases, but there is an important number from Far Eastern communities. A considerable percentage of patients are in a phase that requires treatment.

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