P-8 TRENDS IN ALCOHOL-ASSOCIATED CIRRHOSIS IN CHILE: A POPULATION STUDY BETWEEN 2001 TO 2020.

Conflict of interest

No

Introduction and Objectives

Alcohol-associated cirrhosis (AAC) is the leading cause of death from cirrhosis in the world. In recent years, an increase in alcohol consumption and AAC has been observed, especially in women, young people, low socioeconomic levels, and certain ethnic groups. Objective: To perform a descriptive study of patients hospitalized for AAC and non-alcohol-associated cirrhosis (NAAC) in Chile between 2001 and 2020, stratified by socioeconomic and demographic variables of the patients.

Patients / Materials and Methods

Of 72,096 hospital discharges, 44,971 patients hospitalized for AAC and non-alcohol-associated cirrhosis (NAAC) in Chile between 2001 and 2020, were identified. A descriptive statistical study was carried out on the behavior of the AAC and NAAC at the national and regional levels by sex, age, and health insurance provider. Additionally, a study of patient survival rates was carried out using Kaplan-Meier.

Results and Discussion

The results are detailed in Table 1: presents the number of cases per 100,000 inhabitants in the corresponding group under study.

Conclusions

When calculating the number of discharges per 100,000 inhabitants in Chile over the years, the AAC has remained relatively constant, while the NAAC has shown a reduction of more than 50%, going from 12.8 to 6.2 hospital discharges. Furthermore, of the total discharges due to cirrhosis, nearly two-thirds correspond to AAC.

Regarding the differences between health insurance, a contrast is observed between the AAC and NAAC. AAC is more prevalent in patients with public health insurance, both for men and women. Although NAAC is higher in patients with private health insurance for both sexes, it does not present significant differences between forecast and sex compared to AAC.

Finally, an age trend is observed in discharges due to cirrhosis, both in AAC and NAAC, especially in the age groups of 50-59 and 60-69. Furthermore, it is precisely in these age groups that AAC tends to be more prevalent than NAAC.