Clinical history in ophthalmological patients treated with multivitamin complexes

Asensio-Sánchez, V.M.; Martín-Prieto, A.

doi:10.1016/j.oftale.2017.02.004

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Saldaña Garrido, M. Martínez Rubio, R. Carrión Campo, M.A. Moya Moya, L. Rico Sergado" "autores" => array:5 [ 0 => array:2 [ "nombre" => "J.D." "apellidos" => "Saldaña Garrido" ] 1 => array:2 [ "nombre" => "M." "apellidos" => "Martínez Rubio" ] 2 => array:2 [ "nombre" => "R." "apellidos" => "Carrión Campo" ] 3 => array:2 [ "nombre" => "M.A." "apellidos" => "Moya Moya" ] 4 => array:2 [ "nombre" => "L." 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Asensio-Sánchez, A. Martín-Prieto" "autores" => array:2 [ 0 => array:4 [ "nombre" => "V.M." "apellidos" => "Asensio-Sánchez" "email" => array:1 [ 0 => "victor_asensio@orangemail.es" ] "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "*" "identificador" => "cor0005" ] ] ] 1 => array:2 [ "nombre" => "A." "apellidos" => "Martín-Prieto" ] ] "afiliaciones" => array:1 [ 0 => array:2 [ "entidad" => "Servicio de Oftalmología, Hospital Clínico Universitario, Valladolid, Spain" "identificador" => "aff0005" ] ] "correspondencia" => array:1 [ 0 => array:3 [ "identificador" => "cor0005" "etiqueta" => "⁎" "correspondencia" => "Corresponding author." ] ] ] ] "titulosAlternativos" => array:1 [ "es" => array:1 [ "titulo" => "La historia clínica en pacientes oftalmológicos tratados con complejos multivitamínicos" ] ] "textoCompleto" => "Apart from food intake, vitamin supplements are the only protection against age related macular degeneration. However, said supplements are expensive and compliance is quite doubtful. In addition, manufacturers have different formulations which do not match the dosage recommended in clinical trials, some being too high and others too low. On the other hand, ophthalmologists routinely and sometimes compulsively prescribe said supplements/vitamin complexes for ocular surface diseases, glaucoma, diabetic retinopathy and myopia. In our mind we are under the impression that these supplements are not medicaments and therefore can be prescribed to all patients without fear of side effects. Clinic history is fundamental for prescribing any drug, and vitamins and trace elements must be regarded as such. Said supplements and/or complexes would not be indicated in patients with anticoagulants or anti-aggregates (in 2013, 24.6 million boxes of acetylsalicylic acid were sold in Spain) or in patients with a record of cerebrovascular accidents.<a class="elsevierStyleCrossRef" href="#bib0020">1</a> Said complexes modify their pharmacokinetics when the percentage of fat is high, i.e., in obese patients with a BMI of 30kg/m2 or more.<a class="elsevierStyleCrossRef" href="#bib0025">2</a> Due to poor absorption, said supplements would not be sufficiently effective in patients with chronic inhibition of gastric acidity<a class="elsevierStyleCrossRef" href="#bib0030">3</a> (in 2013 54.4 million boxes of omeprazole were sold in Spain with a medical prescription), or in patients with biliary pathway surgery history (cholecystectomy) or in individuals with diminished HDL. We have studied 500 consecutive patients that were taking vitamin complexes prescribed by an ophthalmologist. Of these, 136 were on anti-platelet agents, 78 were on anticoagulants, 19 had biliary surgery history, 16 had cerebral ischemia history in the past year (16 on anti-platelet agents), 160 were in treatment with proton bomb inhibitors (100 on anti-platelet agents, 15 on anticoagulants, 7 with biliary surgery history) and 26 patients were obese (5 on anti-platelet agents, one on anticoagulants, 6 with antacids and 4 with biliary surgery). This means that in 281 patients out of 500 the vitamin complex prescription was not indicated or directly contraindicated. Therefore it can be concluded that said supplements are prescribed indiscriminately without considering the clinic history or the potential adverse effects derived from their use. It must be borne in mind that said supplements/vitamin complexes are drugs and therefore capable of interacting with other drugs." 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ISSN: 2173-5794
e-ISSN: 1989-7286

Archivos de la Sociedad Española de Oftalmología is the official journal of the Ophthalmology Society of Spain, that has over 4,000 members. It gives priority to the publication of basic, translational and clinic research including reviews, original articles, short communications, editorials, letters to the editor and clinic practice guides related to Ophthalmology and its subspecialties. A small section of the journal is reserved for the most relevant papers presented at the annual Congress of the Society. All manuscripts considered for publication are reviewed by expert examiner peers (double blind). The journal is published monthly and even though its official language is Spanish all articles are translated into English to increase the dissemination of scientific information. At present, Archivos is the only Spanish language Ophthalmology journal indexed in PubMed/MEDLINE in addition to other prestigious international databases such as Scopus.

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Vol. 92. Issue 3.