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Inicio Cirugía Española Quimioprofilaxis en cirugía: problemas y soluciones en su cumplimiento
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Vol. 71. Núm. 2.
Páginas 96-101 (febrero 2002)
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Vol. 71. Núm. 2.
Páginas 96-101 (febrero 2002)
Acceso a texto completo
Quimioprofilaxis en cirugía: problemas y soluciones en su cumplimiento
Chemoprophylaxis in surgery: Problems and solutions in its performance
Visitas
4855
M. Delgado Rodríguez1
Autor para correspondencia
mdelgado@ujaen.es

Correspondencia: Prof. Dr. M. Delgado Rodríguez. Cátedra de Medicina Preventiva. Edificio B-3. 23071 Jaén.
Catedrático de Medicina Preventiva y Salud Pública. Universidad de Jaén
G. Martínez Gallego*, A. Gómez Ortega*, M. Medina Cuadros*
* Servicio de Cirugía General. Hospital Ciudad de Jaén
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Resumen

Desde hace 20 años los principios de la profilaxis antibiótica permanecen vigentes. No obstante, con una gran frecuencia en todos los países, desarrollados o no, se documenta que su incumplimiento es una práctica habitual en cirugía. Los estudios que han abordado el estudio de los determinantes de cumplimiento son escasos. Aunque la información es insuficiente, se ha establecido una serie de factores que pueden influir. Dentro de los factores relacionados con el paciente se encuentran el sexo, el grado de contaminación y la duración de la cirugía, si la cirugía es de urgencia o programada, el momento del día en que se realiza la cirugía, el nivel ASA y la enfermedad subyacente. Dentro de los factores dependientes del cirujano pueden influir el dogmatismo, nihilismo, arrogancia, miedo al fracaso, mercadotecnia de las casas comerciales, sensación de seguridad, falta de formación científica, no diferenciar profilaxis de tratamiento, no diferenciar inflamación de infección, trabajar o no en un hospital docente y la comprobación de que la alteración de la profilaxis recomendada no aumenta el riesgo de infección. Para conseguir que se cumplan las normas de profilaxis antibiótica se sugiere una serie de soluciones, que van desde la evaluación del grado de cumplimiento hasta el aumento de la formación científica, especialmente en la residencia donde el futuro cirujano es más moldeable y adopta las prácticas de sus tutores

Palabras clave:
Profilaxis antibiótica
Infección nosocomial
Frecuencia
Cumplimiento

Since twenty years ago the principles of adequate antibiotic prophylaxis are well established. Nevertheless, a review of medical literature can document that in every country, either developed or not, its inadequate use is very frequent. The studies analyzing the determinants of inadequate use are scarce. Despite this scarcity of data several variables have been identified. Regarding the variables related to patients’ characteristics the next ones influence inadequate use: sex, type of surgical wound, duration of surgery, emergency surgery, time (within the day) of operation, ASA score, and the underlying disease; as regards the variables related to the surgeon the following influence the correct use: dogmatism, nihilism, arrogance, fear to fail, marketing of antibiotics, safety sensation, lack of scientific knowledge, fail in differentiating prophylaxis of treatment and inflammation of infection, to work in a teaching hospital, and the ascertainment that inadequate use does not increase risk of nosocomial infection. Several measures are proposed to improve the adequate use of antibiotic prophylaxis, from the assessment of degree of adherence to the correct principles to the improvement in the knowledge of scientific method, mainly during residency where the future surgeon is more likely to change his attitudes and practices and to adopt the habits of his tutors

Key words:
Antibiotic prophylaxys
Cross infection
Frecuency
Adherence
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Bibliografía
[1.]
M. McDonald, E. Grabsch, C. Marshall, A. Forbes.
Single versus multiple dose antimicrobial prophylaxis for major surgery: a systematic review.
Aust NZ J Surg, 68 (1998), pp. 388-396
[2.]
R. Platt, D.F. Zaleznik, C.G. Hopkins, E.P. Dellinger, A.W. Karchmer, C.S. Bryan, et al.
Perioperative antibiotic prophylaxis for herniorrhaphy and breast surgery.
N Engl J Med, 322 (1990), pp. 153-160
[3.]
P.J. Sanderson.
Assessing the role of prophylactic antibiotics in clean surgery.
J Hosp Infect, 42 (1999), pp. 7-9
[4.]
T.G. Bumakis.
Surgical antimicrobial prophylaxis: principles and guidelines.
Pharmacotherapy, 4 (1984), pp. 248-271
[5.]
A. Silver, A. Eichorn, J. Kral, G. Pickett, P. Barie, V. Pryor, et al.
Timeliness and use of antibiotic prophylaxis in selected inpatient surgical procedures. The Antibiotic Prophylaxis Study Group.
Am J Surg, 171 (1996), pp. 548-552
[6.]
P. Gorecki, M. Schein, J.C. Rucinski, L. Wise.
Antibiotic administration in patients undergoing common surgical procedures in a community teaching hospital: the chaos continues.
World J Surg, 23 (1999), pp. 429-432
[7.]
S. Harbarth, M.H. Samore, D. Lichtenberg, Y. Carmeli.
Prolonged antibiotic prophylaxis after cardiovascular surgery and its effect on surgical site infections and antimicrobial resistance.
Circulation, 101 (2000), pp. 2916-2921
[8.]
D. Zoutman, L. Chau, J. Watterson, T. Mackenzie, M. Djurfeldt.
A Canadian survey of prophylactic antibiotic use among hip-fracture patients.
Infect Control Hosp Epidemiol, 20 (1999), pp. 752-755
[9.]
N. Namias, S. Harvill, S. Ball, M.G. McKenney, J.P. Salomone, J.M. Civetta.
Cost and morbidity associated with antibiotic prophylaxis in the ICU.
J Am Coll Surg, 188 (1999), pp. 225-230
[10.]
P.M. George.
Dermatologists and antibiotic prophylaxis: a survey.
J Am Acad Dermatol, 33 (1995), pp. 418-421
[11.]
C. Martin, X. Viviand, A. Gayte Sorbier, M.C. Saux.
Audit sur 39 centres hospitaliers des pratiques d’antibioprophylaxie en chirurgie et le groupe du sud est pour l’etude de l’antibioprophylaxie.
Ann Fr Anesth Reanim, 17 (1998), pp. 764-768
[12.]
X. Kurz, R. Mertens, O. Ronveaux.
Antimicrobial prophylaxis in surgery in Belgian hospitals: room for improvement.
Eur J Surg, 162 (1996), pp. 15-21
[13.]
A. Markewitz, H.D. Schulte, H.H. Scheld, The Working Group on Cardiothoracic Surgical Intensive Care Medicine of the German Society for Thoracic and Cardiovascular Surgery.
Current practice of peri and postoperative antibiotic therapy in cardiac surgery in Germany.
Thorac Cardiovasc Surg, 47 (1999), pp. 405-410
[14.]
T. Hauer, M. Lacour, P. Gastmeier, S. Schulgen, M. Schumacher, H. Ruden, et al.
Nosokomiale infektionen in Deustschland (NIDEP). Mikrobiologishe diagnostik, antibiotikaprophylaxe und antibiotikatherapie.
Med Klin, 91 (1996), pp. 681-686
[15.]
V. Vaisbrud, D. Raveh, Y. Schlesinger, A.M. Yinnon.
Surveillance of antimicrobial prophylaxis for surgical procedures.
Infect Control Hosp Epidemiol, 20 (1999), pp. 610-613
[16.]
M. Thomas, S. Govil, B.V. Moses, A. Joseph.
Monitoring antibiotic use in a primary and a tertiary care hospital.
J Clin Epidemiol, 49 (1996), pp. 251-254
[17.]
I. Heineck, M.B. Ferreira, E.P. Schenkel.
Prescribing practice for antibiotic prophylaxis for 3 commonly performed surgeries in a teaching hospital in Brazil.
Am J Infect Control, 27 (1999), pp. 296-300
[18.]
C. Codina, A. Trilla, N. Riera, M. Tuset, X. Carne, J. Ribas, et al.
Perioperative antibiotic prophylaxis in Spanish hospitals: results of a questionnaire survey. Hospital Pharmacy Antimicrobial Prophylaxis Study Group.
Infect Control Hosp Epidemiol, 20 (1999), pp. 436-439
[19.]
M. Medina-Cuadros, M. Sillero-Arenas, G. Martínez-Gallego, M. Delgado-Rodríguez.
Risk factors of surgical wound infection in patients undergoing herniorrhaphy.
Eur J Surg, 163 (1997), pp. 191-198
[20.]
G. Martínez Gallego, M. Sillero Arenas, M. Medina Cuadros, M. Delgado-Rodríguez.
Quimioprofilaxis e infección de la herida en pacientes operados de hernia abdominal.
Cir Andaluza, 8 (1997), pp. 110-115
[21.]
P.E. Collier, M. Rudolph, D. Ruckert, T. Osella, N.A. Collier, M. Ferrero.
Are preoperative antibiotics administered preoperatively?.
Am J Med Qual, 13 (1998), pp. 94-97
[22.]
N.J. Ehrenkranz.
Antimicrobial prophylaxis in surgery: mechanisms, misconceptions, and mischief.
Infec Control Hosp Epidemiol, 14 (1993), pp. 99-106
[23.]
D.H. Wittman, M. Schein.
Let us shorten antibiotic prophylaxis and therapy in surgery.
Am J Surg, 172 (1996), pp. S26-S32
[24.]
B. Millat, A. Fingerhut, Y. Flamant, J.M. Hay, P.L. Fagniez, A. Farah, et al.
and the French Association for Research in Surgery (AURC and ACAPLM). Survey of the impact of randomised clinical trials on surgical practice in France.
Eur J Surg, 165 (1999), pp. 87-94
[25.]
S. Harbarth, M.H. Samore, D. Lichtenberg, Y. Carmeli.
Is prolonged antibiotic prophylaxis after major surgery associated with an increased risk of nosocomial bloodstream infection? [letter].
J Am Coll Surg, 190 (2000), pp. 503-504
[26.]
M. Medina-Cuadros, M. Sillero-Arenas, G. Martínez Gallego, M. Delgado-Rodríguez.
Surgical wound infections diagnosed after discharge from hospital. Epidemiological differences with in-hospital infections.
Am J Infect Control, 24 (1996), pp. 421-428
[27.]
M. Delgado-Rodríguez, A. Gómez-Ortega, M. Sillero-Arenas, J. Llorca.
Lpidemiology of surgical site infection diagnosed after discharge. A prospective cohort study.
Infect Control Hosp Epidemiol, 22 (2001), pp. 24-30
[28.]
V. Thamlikiktul, S. Danchaivijitr, S. Kongpattanakul, S. Chokloikaew.
Impact of an educational program on antibiotic use in a tertiary care hospital in a developing country.
J Clin Epidemiol, 5I (1998), pp. 773-778
[29.]
C.M. Avery, N. Jamieson, R.Y. Calne.
Effective administration of heparin and antibiotic prophylaxis.
Br J Surg, 82 (1995), pp. 1136-1137
[30.]
I.C. Gyssens, I.E.J. Geerligs, M.G. Nannini Bergman, J.T.A. Knape, Y.A. Hekster, J.W.M. Van der Meer.
Optimizing the timing of antimicrobial prophylaxis in surgery: an intervention study.
J Antimicrob Chemother, 38 (1996), pp. 301-308
[31.]
J.A. Schell, C.G. Bynum, G.J. Fortune, G.R. Laiben, Y.J. Chang, J.A. Pirner.
Perioperative antibiotics in nonemergency bowel surgery: a quality improvement project.
South Med J, 91 (1998), pp. 900-908
[32.]
S.L. Pestotnik, D.C. Classen, R.S. Evans, J.P. Burke.
Implementing antibiotic practice guidelines through computer assisted decision support; clinical and financial outcomes.
Ann Intern Med, 124 (1996), pp. 884-890
[33.]
I.C. Gyssens.
Preventing postoperative infections: current treatment recommendations.
Drugs, 57 (1999), pp. 175-185
[34.]
L.L. Leape.
Translating medical science into medical practice. Do we need a national medical standards board?.
JAMA, 273 (1995), pp. 1534-1537
[35.]
J. Lomas, T.B. Haynes.
A taxonomy and critical review of tested strategies for the application of clinical practice recommendations: from “official” to “individual” clinical policy.
Am J Prev Med, 4 (1988), pp. 77-94
[36.]
J.M. Grinsahw, I.T. Russell.
Effect of clinical guidelines on medical practice: a systematic review of rigourous evaluations.
Lancet, 342 (1993), pp. 1317-1321
[37.]
M.J. Solomon, A. Laxamana, L. Devore, R.S. McLeod.
Randomized controlled trials in surgery.
Surgery, 115 (1994), pp. 707-715
Copyright © 2002. Asociación Española de Cirujanos
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