Estadísticas

 array:18 [
  "pii" => "5354"
  "issn" => "0009739X"
  "estado" => "S300"
  "fechaPublicacion" => "1998-05-01"
  "documento" => "article"
  "crossmark" => 0
  "subdocumento" => "fla"
  "cita" => "Cir Esp. 1998;63:378-82"
  "abierto" => array:3 [
    "ES" => true
    "ES2" => true
    "LATM" => true
  ]
  "gratuito" => true
  "lecturas" => array:2 [
    "total" => 3091
    "formatos" => array:3 [
      "EPUB" => 8
      "HTML" => 2935
      "PDF" => 148
    ]
  ]
  "itemSiguiente" => array:15 [
    "pii" => "5355"
    "issn" => "0009739X"
    "estado" => "S300"
    "fechaPublicacion" => "1998-05-01"
    "documento" => "article"
    "crossmark" => 0
    "subdocumento" => "fla"
    "cita" => "Cir Esp. 1998;63:383-5"
    "abierto" => array:3 [
      "ES" => true
      "ES2" => true
      "LATM" => true
    ]
    "gratuito" => true
    "lecturas" => array:2 [
      "total" => 1655
      "formatos" => array:3 [
        "EPUB" => 8
        "HTML" => 1497
        "PDF" => 150
      ]
    ]
    "es" => array:8 [
      "idiomaDefecto" => true
      "titulo" => "Carcinoma mixto de mama con componente mucinoso y lobulillar infiltrante"
      "tieneTextoCompleto" => 0
      "tieneResumen" => array:2 [
        0 => "es"
        1 => "en"
      ]
      "paginas" => array:1 [
        0 => array:2 [
          "paginaInicial" => "383"
          "paginaFinal" => "385"
        ]
      ]
      "titulosAlternativos" => array:1 [
        "en" => array:1 [
          "titulo" => "Mixed lobular and mucinous carcinoma of the breast"
        ]
      ]
      "contieneResumen" => array:2 [
        "es" => true
        "en" => true
      ]
      "autores" => array:1 [
        0 => array:2 [
          "autoresLista" => "M Veiga, B Madrigal, MJ Pérez del Río, M Herreros, M Martín, M Seco, MF Fresno, A Herrero"
          "autores" => array:8 [
            0 => array:2 [
              "Iniciales" => "M"
              "apellidos" => "Veiga"
            ]
            1 => array:2 [
              "Iniciales" => "B"
              "apellidos" => "Madrigal"
            ]
            2 => array:2 [
              "Iniciales" => "MJ"
              "apellidos" => "Pérez del Río"
            ]
            3 => array:2 [
              "Iniciales" => "M"
              "apellidos" => "Herreros"
            ]
            4 => array:2 [
              "Iniciales" => "M"
              "apellidos" => "Martín"
            ]
            5 => array:2 [
              "Iniciales" => "M"
              "apellidos" => "Seco"
            ]
            6 => array:2 [
              "Iniciales" => "MF"
              "apellidos" => "Fresno"
            ]
            7 => array:2 [
              "Iniciales" => "A"
              "apellidos" => "Herrero"
            ]
          ]
        ]
      ]
    ]
    "idiomaDefecto" => "es"
    "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/5355?idApp=UINPBA00004N"
    "url" => "/0009739X/0000006300000005/v0_201402051829/5355/v0_201402051829/es/main.assets"
  ]
  "itemAnterior" => array:15 [
    "pii" => "5353"
    "issn" => "0009739X"
    "estado" => "S300"
    "fechaPublicacion" => "1998-05-01"
    "documento" => "article"
    "crossmark" => 0
    "subdocumento" => "fla"
    "cita" => "Cir Esp. 1998;63:373-7"
    "abierto" => array:3 [
      "ES" => true
      "ES2" => true
      "LATM" => true
    ]
    "gratuito" => true
    "lecturas" => array:2 [
      "total" => 3050
      "formatos" => array:3 [
        "EPUB" => 7
        "HTML" => 2877
        "PDF" => 166
      ]
    ]
    "es" => array:8 [
      "idiomaDefecto" => true
      "titulo" => "Estudio comparativo entre la flebografía poplítea dinámica y el Eco-Doppler en color en el diagnóstico de la insuficiencia venosa en el hueco poplíteo"
      "tieneTextoCompleto" => 0
      "tieneResumen" => array:2 [
        0 => "es"
        1 => "en"
      ]
      "paginas" => array:1 [
        0 => array:2 [
          "paginaInicial" => "373"
          "paginaFinal" => "377"
        ]
      ]
      "titulosAlternativos" => array:1 [
        "en" => array:1 [
          "titulo" => "Comparison between dynamic popliteal phlebography and color Doppler ultrasonography in the diagnosis of venous insufficiency in the popliteal fossa"
        ]
      ]
      "contieneResumen" => array:2 [
        "es" => true
        "en" => true
      ]
      "autores" => array:1 [
        0 => array:2 [
          "autoresLista" => "F Díaz Gómez, P Castells Ferrer, E Recio Valenzuela, J García Armengol, C Fernández Martínez, JV Roig Vila"
          "autores" => array:6 [
            0 => array:2 [
              "Iniciales" => "F"
              "apellidos" => "Díaz Gómez"
            ]
            1 => array:2 [
              "Iniciales" => "P"
              "apellidos" => "Castells Ferrer"
            ]
            2 => array:2 [
              "Iniciales" => "E"
              "apellidos" => "Recio Valenzuela"
            ]
            3 => array:2 [
              "Iniciales" => "J"
              "apellidos" => "García Armengol"
            ]
            4 => array:2 [
              "Iniciales" => "C"
              "apellidos" => "Fernández Martínez"
            ]
            5 => array:2 [
              "Iniciales" => "JV"
              "apellidos" => "Roig Vila"
            ]
          ]
        ]
      ]
    ]
    "idiomaDefecto" => "es"
    "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/5353?idApp=UINPBA00004N"
    "url" => "/0009739X/0000006300000005/v0_201402051829/5353/v0_201402051829/es/main.assets"
  ]
  "es" => array:10 [
    "idiomaDefecto" => true
    "titulo" => "Carcinoma anaplásico de tiroides. Estado actual"
    "tieneTextoCompleto" => 0
    "paginas" => array:1 [
      0 => array:2 [
        "paginaInicial" => "378"
        "paginaFinal" => "382"
      ]
    ]
    "autores" => array:1 [
      0 => array:2 [
        "autoresLista" => "F Villalba Ferrer, J Puche Pla, MJ García Coret, A Bordallo Cortina, MI Durán Bermejo, E Martí Cuñat, E de la Morena Valenzuela"
        "autores" => array:7 [
          0 => array:2 [
            "Iniciales" => "F"
            "apellidos" => "Villalba Ferrer"
          ]
          1 => array:2 [
            "Iniciales" => "J"
            "apellidos" => "Puche Pla"
          ]
          2 => array:2 [
            "Iniciales" => "MJ"
            "apellidos" => "García Coret"
          ]
          3 => array:2 [
            "Iniciales" => "A"
            "apellidos" => "Bordallo Cortina"
          ]
          4 => array:2 [
            "Iniciales" => "MI"
            "apellidos" => "Durán Bermejo"
          ]
          5 => array:2 [
            "Iniciales" => "E"
            "apellidos" => "Martí Cuñat"
          ]
          6 => array:2 [
            "Iniciales" => "E"
            "apellidos" => "de la Morena Valenzuela"
          ]
        ]
      ]
    ]
    "titulosAlternativos" => array:1 [
      "en" => array:1 [
        "titulo" => "Anaplastic thyroid carcinoma. Current status"
      ]
    ]
    "tienePdf" => false
    "PalabrasClave" => array:2 [
      "es" => array:1 [
        0 => array:4 [
          "clase" => "keyword"
          "titulo" => "Palabras clave"
          "identificador" => "xpalclavsec293855"
          "palabras" => array:2 [
            0 => "Carcinoma anaplásico de tiroides"
            1 => "Carcinoma indiferenciado de tiroides"
          ]
        ]
      ]
      "en" => array:1 [
        0 => array:4 [
          "clase" => "keyword"
          "titulo" => "Keywords"
          "identificador" => "xpalclavsec293856"
          "palabras" => array:2 [
            0 => "Anaplastic thyroid carcinoma"
            1 => "Undifferentiated thyroid carcinoma"
          ]
        ]
      ]
    ]
    "tieneResumen" => true
    "resumen" => array:2 [
      "es" => array:1 [
        "resumen" => "La iodoprofilaxis&#44; el tratamiento m&#225;s precoz y radical de los carcinomas diferenciados y el mejor uso de la radioterapia externa y del yodo radiactivo han disminuido la frecuencia del c&#225;ncer anapl&#225;sico de tiroides&#44; pero la mayor influencia en este descenso se debe al menor error diagn&#243;stico&#46; T&#233;cnicas como la inmunohistoqu&#237;mica y la microscopia electr&#243;nica permiten el diagn&#243;stico diferencial con otras neoplasias&#44; confundidas en ocasiones&#44; con el carcinoma anapl&#225;sico de tiroides&#46; <br/>El carcinoma anapl&#225;sico de tiroides tiene alta agresividad local&#59; el 80&#37; son extraglandulares en el momento del diagn&#243;stico y los pacientes fallecen frecuentemente por asfixia&#46; Son frecuentes las met&#225;stasis ganglionares &#40;10-45&#37;&#41; o a distancia &#40;10-48&#37;&#41; y el pron&#243;stico es fatal&#44; con una supervivencia media de 7 meses&#46; Influyen en el pron&#243;stico&#44; el tama&#241;o de la neoplasia&#44; los s&#237;ntomas locales y las met&#225;stasis a distancia&#44; pero no las adenopat&#237;as metast&#225;sicas&#46; <br/>Actualmente&#44; el mejor tratamiento es el multimodal con radioterapia hiperfraccionada&#44; quimioterapia y cirug&#237;a&#46; Con la terapia multimodal no se consiguen controlar las met&#225;stasis a distancia&#44; pero se controla el crecimiento local en el 68&#37; de los pacientes"
      ]
      "en" => array:1 [
        "resumen" => "Iodine prophylaxis&#44; the earlier and more radical treatment of differentiated carcinomas and the more effective use of external radiotherapy and radioiodine therapy have reduced the incidence of anaplastic thyroid carcinoma&#44; but the major factor in this decreased frequency is the lower rate of diagnostic error&#46; Techniques such as immunohistochemistry and electron microscopy aid in the differential diagnosis to rule out other neoplasms that are occasionally confused with anaplastic thyroid carcinoma&#46; <br/>Locally&#44; anaplastic thyroid carcinoma has a highly aggressive behavior&#46; At the time of diagnosis&#44; 80&#37; of these lesions are extraglandular&#59; thus&#44; the patients often die of asphyxia&#46; Lymph node metastases are common &#40;10&#37; to 45&#37;&#41;&#44; as are distant metastases &#40;10&#37; to 48&#37;&#41;&#44; and the prognosis is extremely poor&#44; with a mean survival time of 7 months&#46; The size of the neoplasm&#44; the local symptoms and distant metastases play a role in the prognosis&#44; but the presence of metastatic lymph nodes does not&#46; <br/>At the present time&#44; multimodal therapy involving hyperfractionated radiotherapy&#44; chemotherapy and surgery is the best strategy&#46; It does not help to control distant metastases but is effective in limiting local spread in 68&#37; of patients"
      ]
    ]
  ]
  "idiomaDefecto" => "es"
  "url" => "/0009739X/0000006300000005/v0_201402051829/5354/v0_201402051829/es/main.assets"
  "Apartado" => array:4 [
    "identificador" => "15022"
    "tipo" => "SECCION"
    "es" => array:2 [
      "titulo" => "Revisi&#243;n de conjunto"
      "idiomaDefecto" => true
    ]
    "idiomaDefecto" => "es"
  ]
  "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/5354?idApp=UINPBA00004N"
]