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EDITORIAL
Mediterranean diet, physical activity and ideal body weight, all wanting in Spanish children and adolescents
La adherencia a la dieta mediterránea, la actividad física y el peso corporal idóneo dejan mucho que desear en niños y adolescents españoles
Emilio Ros
Lipid Clinic, Endocrinology and Nutrition Service, Institut d’Investigacions Biomèdiques August Pi Sunyer (IDIBAPS), Hospital Clínic, Barcelona and CIBER Fisiopatología de la Obesidad y Nutrición (CIBEROBN), Instituto de Salud Carlos III (ISCIII), Spain
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        "titulo" => "La adherencia a la dieta mediterr&#225;nea&#44; la actividad f&#237;sica y el peso corporal id&#243;neo dejan mucho que desear en ni&#241;os y adolescents espa&#241;oles"
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    "textoCompleto" => "<span class="elsevierStyleSections"><p id="par0005" class="elsevierStylePara elsevierViewall">There is consistent epidemiological evidence that an unhealthy lifestyle &#40;smoking&#44; sedentariness&#44; abstention or excess alcohol&#44; poor diet&#44; and overweight or obesity&#41; contributes nearly 80&#37; of population-attributable risk of cardiovascular diseases &#40;CVD&#41;<a class="elsevierStyleCrossRefs" href="#bib0005"><span class="elsevierStyleSup">1&#44;2</span></a>&#46; The converse&#44; i&#46;e&#46;&#44; that a salutary lifestyle will afford close to 80&#37; CVD protection&#44; is also valid&#44; as attested by a recent report from a large Swedish community study <a class="elsevierStyleCrossRef" href="#bib0015"><span class="elsevierStyleSup">3</span></a>&#46; Thus&#44; lifestyle changes are critical for the prevention of CVD at both the individual and the population level&#46; Presently there is overwhelming evidence that smoking is harmful&#44; while there are still controversies on which is a safe level of alcohol intake <a class="elsevierStyleCrossRef" href="#bib0020"><span class="elsevierStyleSup">4</span></a>&#46; On the other hand&#44; there is continuous progress on the epidemiology&#44; health consequences and management of excess body weight&#44; physical inactivity and poor dietary habits&#46;</p><p id="par0010" class="elsevierStylePara elsevierViewall">Currently the obesity pandemic and its attendant enhanced risk for premature mortality&#44; CVD&#44; type 2 diabetes&#44; cognitive impairment&#44; some types of cancer and other chronic diseases is a major global public health concern&#44; as both the prevalence and disease burden related to a high body mass index &#40;BMI&#41; are increasing globally&#44; and the rate of increase is steeper in children and adolescents than in adults <a class="elsevierStyleCrossRef" href="#bib0025"><span class="elsevierStyleSup">5</span></a>&#46; Excessive body weight is particularly important at younger ages because it predicts adverse health consequences throughout the life-course&#46; Changes in the food environment have resulted in more processed and energy-dense foods being increasingly available&#44; accessible&#44; and affordable&#59; together with aggressive marketing of such foods&#44; these are likely to be major drivers of excess energy intake and weight gain among different populations&#44; children being particularly susceptible <a class="elsevierStyleCrossRef" href="#bib0030"><span class="elsevierStyleSup">6</span></a>&#46; The reduced opportunities for physical activity that have followed urbanization&#44; major changes in means of mechanic transportation&#44; and the pervasiveness of leisure-time sedentary activities like TV-watching&#44; videogames&#44; internet navigation and smart phone use can also be considered as potential drivers&#46; Spain is no exception to the obesity epidemic&#58; according to a recent survey&#44; overweight has remained stable in the last 25 years at nearly 35&#37; of the adult population&#44; but obesity has more than doubled from 8&#37; to 16&#46;5&#37; <a class="elsevierStyleCrossRef" href="#bib0035"><span class="elsevierStyleSup">7</span></a>&#46; Similar rates of overweight and obesity have been reported for Spanish children <a class="elsevierStyleCrossRef" href="#bib0040"><span class="elsevierStyleSup">8</span></a>&#46;</p><p id="par0015" class="elsevierStylePara elsevierViewall">In this issue of the journal&#44; Rosa-Guillam&#243;n et al&#46; report on associations between body weight&#44; physical activity and adherence to the Mediterranean diet &#40;MeDiet&#41; in a cross-sectional study of a non-random sample of 520 schoolchildren aged 8 to 17 years attending public schools in the region of Murcia <a class="elsevierStyleCrossRef" href="#bib0045"><span class="elsevierStyleSup">9</span></a>&#46; Even though the socioeconomic status of the families of the study subjects is defined as medium-high&#44; which is usually associated with healthier dietary behaviors&#44; lower obesity rates&#44; and better overall health indexes compared with disadvantaged social groups <a class="elsevierStyleCrossRef" href="#bib0050"><span class="elsevierStyleSup">10</span></a>&#44; the prevalence of overweight&#47;obesity was 40&#37;&#46; A low-quality diet with poor adherence to the MeDiet was present in 29&#37; of males and 33&#37; of females&#44; while 28&#37; overall reported a low physical activity level and only 2&#37; had high physical activity&#46; These data concur with a recent report of the ANIBES study&#44; a cross-sectional investigation conducted on a random sample of the Spanish population aged 9&#8211;75 years&#44; which shows that a high proportion of both young people and adults in Spain have poor dietary habits and low physical activity <a class="elsevierStyleCrossRef" href="#bib0055"><span class="elsevierStyleSup">11</span></a>&#46; Another finding of the study of Rosa-Guillam&#243;n et al&#46; worth mentioning is that the more physically active schoolchildren reported a better adherence to the MeDiet&#44; which makes sense&#44; but this association was independent of body weight status&#44; i&#46;e&#46;&#44; both exercising normal weight and overweight&#47;obese individuals followed the MeDiet to a greater extent that those physically inactive&#44; regardless of adiposity <a class="elsevierStyleCrossRef" href="#bib0045"><span class="elsevierStyleSup">9</span></a>&#46; These might be a spurious result&#44; due to low statistical power and lack of adjusting for critical confounders&#44; such as energy intake&#46; Indeed&#44; available evidence suggests that compliance with the MeDiet is associated with a lower body weight independently of physical activity in both children <a class="elsevierStyleCrossRef" href="#bib0060"><span class="elsevierStyleSup">12</span></a> and adults <a class="elsevierStyleCrossRefs" href="#bib0065"><span class="elsevierStyleSup">13&#44;14</span></a>&#46; Randomized controlled trials &#40;RCTs&#41; have also demonstrated that an energy-restricted MeDiet is superior to low-fat or low-carbohydrate dietary patterns to obtain significant loss of weight and medium-term maintenance of weight loss in persons with overweight or obesity <a class="elsevierStyleCrossRefs" href="#bib0075"><span class="elsevierStyleSup">15&#8211;17</span></a>&#46; Attesting to the long-reaching beneficial effect of the MeDiet&#44; adherence to this dietary pattern by pregnant mothers results in reduced adiposity in the offspring at 4 and 7 years of age <a class="elsevierStyleCrossRef" href="#bib0090"><span class="elsevierStyleSup">18</span></a>&#46; Favorable effect tracking into the next generation might be attributable to advantageous fetal epigenetic changes by the MeDiet&#44; which seems a biological feat&#33;</p><p id="par0020" class="elsevierStylePara elsevierViewall">Individuals adhering to the MeDiet tend to have healthier lifestyles than those with lesser compliance&#44; and this can explain in part why they are more physically active&#46; Interestingly&#44; a recent systematic review of 58 papers describing rates of adherence to the MeDiet in various children and adolescent populations points out that most studies showed MeDiet adherence to be directly associated with physical activity and inversely with sedentary behavior <a class="elsevierStyleCrossRef" href="#bib0095"><span class="elsevierStyleSup">19</span></a>&#46; Although not considered as important as unhealthy diets rich in energy-dense ultra-processed foods and sugar-sweetened beverages&#44; sedentariness &#40;or lack of physical activity&#41; is also relevant in the obesity pandemic&#44; and promotion of exercise is effective to help lose weight in overweight and obese individuals <a class="elsevierStyleCrossRef" href="#bib0100"><span class="elsevierStyleSup">20</span></a>&#46; Concurring with the low overall adherence to the MeDiet by Spanish children and adolescents&#44; the present situation for physical activity is also unsatisfactory&#44; as trend data from the Spanish National Health Survey for 2016 show that the proportion who follow the recommendations to spend at least 60<span class="elsevierStyleHsp" style=""></span>minutes daily 5 times per week in moderate-to-vigorous exercise reaches only 31&#37; males and 15&#37; females 3 to 18 years old <a class="elsevierStyleCrossRef" href="#bib0105"><span class="elsevierStyleSup">21</span></a>&#46; Underlining the importance of fulfilling both the MeDiet and appropriate exercise&#44; a recent meta-analysis of 11 RCTs conducted in adults populations concluded that&#44; compared to control conditions&#44; promoting the MeDiet in combination with physical activity has a strong beneficial effect on body weight&#44; while the effect on other cardiometabolic risk factors is moderate <a class="elsevierStyleCrossRef" href="#bib0110"><span class="elsevierStyleSup">22</span></a>&#46;</p><p id="par0025" class="elsevierStylePara elsevierViewall">The PREDIMED RCT showed that promotion of the MeDiet together with supplementation of healthy fatty foods &#40;extra-virgin olive oil and nuts&#41; induced a 30&#37; reduction of CVD events in older adults at high cardiovascular risk but no prior CVD events&#44; thus providing the highest level of scientific evidence for the efficacy of a food pattern&#44; in this case the MeDiet&#44; in the primary prevention of CVD <a class="elsevierStyleCrossRef" href="#bib0115"><span class="elsevierStyleSup">23</span></a>&#46; In PREDIMED&#44; though&#44; the diets were isoenergetic and increased physical activity was not recommended&#46; To learn whether a reduced-energy MeDiet plus exercise promotion leading to sustained weight loss in persons with overweight&#47;obesity and features of the metabolic syndrome would go a step further in CVD prevention&#44; the PREDIMED-Plus RCT was launched in September 2013&#46; This trial thus tackles the three CVD risk factors dealt with in this paper&#58; diet&#44; body weight and physical activity&#44; although its aim of CVD prevention through weight loss mandates to study older individuals at high cardiovascular risk&#44; not young ones <a class="elsevierStyleCrossRef" href="#bib0120"><span class="elsevierStyleSup">24</span></a>&#46; Preliminary results at 1 year in the first 626 study subjects recruited has shown that such intensive lifestyle intervention was effective in decreasing adiposity and improving cardiovascular risk factors <a class="elsevierStyleCrossRef" href="#bib0125"><span class="elsevierStyleSup">25</span></a>&#46;</p><p id="par0030" class="elsevierStylePara elsevierViewall">Overall&#44; the data of Rosa-Guillam&#243;n et al&#46; and the available epidemiological evidence indicate that a great effort needs to be made at the public health level among Spanish youth to foster adherence to the MeDiet and fight against sedentariness to both forestall undue weight gain and promote good health now and in the life-course&#46; It is also critical to attempt to close the ever increasing gap between rich and poor&#44; which entails a great disparity in dietary habits and overall lifestyle translating into obesity&#44; increased chronic disease rates&#44; and a shortened life span for the more disadvantaged&#46; Eventually&#44; the results of the PREDIMED-Plus trial will tell us whether sustained weight loss through diet and exercise in overweight&#47;obese individuals results in prevention from CVD and other non communicable diseases&#46;</p></span>"
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                      "titulo" => "Primary prevention of stroke by healthy lifestyle"
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                            0 => "S&#46;E&#46; Chiuve"
                            1 => "K&#46;M&#46; Rexrode"
                            2 => "D&#46; Spiegelman"
                            3 => "G&#46; Logroscino"
                            4 => "J&#46;E&#46; Manson"
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                        "fecha" => "2008"
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                        "paginaInicial" => "947"
                        "paginaFinal" => "954"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/18697819"
                            "web" => "Medline"
                          ]
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              "identificador" => "bib0015"
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                    0 => array:2 [
                      "titulo" => "Low-risk diet and lifestyle habits in the primary prevention of myocardial infarction in men&#58; a population-based prospective cohort study"
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                            3 => "A&#46; Wolk"
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                        "tituloSerie" => "J Am Coll Cardiol&#46;"
                        "fecha" => "2014"
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                        "paginaInicial" => "1299"
                        "paginaFinal" => "1306"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/25257629"
                            "web" => "Medline"
                          ]
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              "identificador" => "bib0020"
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                    0 => array:2 [
                      "titulo" => "Risk thresholds for alcohol consumption&#58; combined analysis of individual-participant data for 599 912 current drinkers in 83 prospective studies"
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                          "etal" => true
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                            2 => "A&#46;S&#46; Butterworth"
                            3 => "P&#46; Willeit"
                            4 => "S&#46; Warnakula"
                            5 => "T&#46; Bolton"
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                        "tituloSerie" => "Lancet&#46;"
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                        "paginaInicial" => "1513"
                        "paginaFinal" => "1523"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/29676281"
                            "web" => "Medline"
                          ]
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              ]
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              "identificador" => "bib0025"
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                0 => array:1 [
                  "referenciaCompleta" => "The GBD 2015 Obesity Collaborators&#46; Health effects of overweight and obesity in 195 countries over 25 years&#46; N Engl J Med 2017&#59;377&#58;13-27&#46;"
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              ]
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              "identificador" => "bib0030"
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                    0 => array:2 [
                      "titulo" => "The global obesity pandemic&#58; shaped by global drivers and local environments"
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                        0 => array:2 [
                          "etal" => false
                          "autores" => array:7 [
                            0 => "B&#46;A&#46; Swinburn"
                            1 => "G&#46; Sacks"
                            2 => "K&#46;D&#46; Hall"
                            3 => "K&#46; McPherson"
                            4 => "D&#46;T&#46; Finegood"
                            5 => "M&#46;L&#46; Moodie"
                            6 => "S&#46;L&#46; Gortmaker"
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                  "host" => array:1 [
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                        "fecha" => "2011"
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                        "paginaInicial" => "804"
                        "paginaFinal" => "814"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/21872749"
                            "web" => "Medline"
                          ]
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              "identificador" => "bib0035"
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                      "titulo" => "Prevalencia de obesidad y diabetes en adultos espa&#241;oles&#44; 1987-2012"
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                          "etal" => false
                          "autores" => array:5 [
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                            2 => "M&#46; Ruiz-Canela"
                            3 => "A&#46; Gea"
                            4 => "M&#46;A&#46; Martinez-Gonzalez"
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                        "paginaFinal" => "256"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/28081903"
                            "web" => "Medline"
                          ]
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                      "titulo" => "The ALADINO study&#58; A national study of prevalence of overweight and obesity in Spanish children in 2011"
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                    0 => array:2 [
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                        "tituloSerie" => "Biomed Res Int&#46;"
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                        "paginaInicial" => "163687"
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                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/24089663"
                            "web" => "Medline"
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              "identificador" => "bib0045"
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                      "titulo" => "Dieta mediterr&#225;nea&#44; estado de peso y actividad f&#237;sica en escolares de la Regi&#243;n de Murcia"
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                            3 => "L&#46; Tarraga-Marcos"
                            4 => "PJ&#46; Tarraga-L&#243;pez"
                          ]
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                      ]
                    ]
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                  "host" => array:1 [
                    0 => array:2 [
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                        "tituloSerie" => "Clin Investig Arterioscler&#46;"
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                        "paginaInicial" => "1"
                        "paginaFinal" => "7"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/30503075"
                            "web" => "Medline"
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              "identificador" => "bib0050"
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                        "tituloSerie" => "Nutr Rev&#46;"
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                        "paginaFinal" => "S39"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/19453676"
                            "web" => "Medline"
                          ]
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              "identificador" => "bib0055"
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                      "titulo" => "Lifestyle patterns and weight status in Spanish adults&#58; The ANIBES study"
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                            5 => "L&#46; Serra-Majem"
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                        "paginaInicial" => "E606"
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                            "web" => "Medline"
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                      "titulo" => "Mediterranean diet&#44; overweight and body composition in children from eight European countries&#58; cross-sectional and prospective results from the IDEFICS study"
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                            4 => "V&#46; Pala"
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                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/23870847"
                            "web" => "Medline"
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              "identificador" => "bib0065"
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                0 => array:2 [
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                      "titulo" => "Obesity and the Mediterranean diet&#58; a systematic review of observational and intervention studies"
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                        "link" => array:1 [
                          0 => array:2 [
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                            "web" => "Medline"
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                    0 => array:2 [
                      "titulo" => "A 14-item Mediterranean diet assessment tool and obesity indexes among high-risk subjects&#58; the PREDIMED trial"
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                          "etal" => true
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                            "web" => "Medline"
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                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/18635428"
                            "web" => "Medline"
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                            "web" => "Medline"
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              "identificador" => "bib0085"
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                0 => array:3 [
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                      "titulo" => "Adherence to the Mediterranean diet during pregnancy and offspring adiposity and cardiometabolic traits in childhood"
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                            "web" => "Medline"
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              "identificador" => "bib0095"
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                    0 => array:2 [
                      "titulo" => "Exercise&#44; health outcomes&#44; and p&#230;diatric obesity&#58; A systematic review of meta-analyses"
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                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/30054135"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            19 => array:3 [
              "identificador" => "bib0100"
              "etiqueta" => "20"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Adherence to the Mediterranean Diet in children and adolescents&#58; A systematic review"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:3 [
                            0 => "P&#46; Iaccarino Idelson"
                            1 => "L&#46; Scalfi"
                            2 => "G&#46; Valerio"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1016/j.numecd.2017.01.002"
                      "Revista" => array:6 [
                        "tituloSerie" => "Nutr Metab Cardiovasc Dis&#46;"
                        "fecha" => "2017"
                        "volumen" => "27"
                        "paginaInicial" => "283"
                        "paginaFinal" => "299"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/28254269"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            20 => array:3 [
              "identificador" => "bib0105"
              "etiqueta" => "21"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Results from Spain&#39;s 2018 report card on physical activity for children and youth"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:5 [
                            0 => "B&#46; Roman-Vi&#241;as"
                            1 => "F&#46; Zazo"
                            2 => "J&#46; Mart&#237;nez-Mart&#237;nez"
                            3 => "S&#46; Aznar-La&#237;n"
                            4 => "L&#46; Serra-Majem"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1123/jpah.2018-0464"
                      "Revista" => array:7 [
                        "tituloSerie" => "J Phys Act Health&#46;"
                        "fecha" => "2018"
                        "volumen" => "15"
                        "numero" => "S2"
                        "paginaInicial" => "S411"
                        "paginaFinal" => "S412"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/30475128"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            21 => array:3 [
              "identificador" => "bib0110"
              "etiqueta" => "22"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "The combined effect of promoting the Mediterranean diet and physical activity on metabolic risk factors in adults&#58; a systematic review and meta-analysis of randomised controlled trials"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:7 [
                            0 => "E&#46; Malakou"
                            1 => "M&#46; Linardakis"
                            2 => "M&#46;E&#46;G&#46; Armstrong"
                            3 => "D&#46; Zannidi"
                            4 => "C&#46; Foster"
                            5 => "L&#46; Johnson"
                            6 => "A&#46; Papadaki"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.3390/nu10111577"
                      "Revista" => array:5 [
                        "tituloSerie" => "Nutrients&#46;"
                        "fecha" => "2018"
                        "volumen" => "10"
                        "paginaInicial" => "E1577"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/30366431"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            22 => array:3 [
              "identificador" => "bib0115"
              "etiqueta" => "23"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Primary prevention of cardiovascular disease with a Mediterranean diet supplemented with extra-virgin olive oil or nuts"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "R&#46; Estruch"
                            1 => "E&#46; Ros"
                            2 => "J&#46; Salas-Salvad&#243;"
                            3 => "M&#46;I&#46; Covas"
                            4 => "D&#46; Corella"
                            5 => "F&#46; Ar&#243;s"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1056/NEJMoa1800389"
                      "Revista" => array:5 [
                        "tituloSerie" => "N Engl J Med&#46;"
                        "fecha" => "2018"
                        "volumen" => "378"
                        "paginaInicial" => "e34"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/29897866"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            23 => array:3 [
              "identificador" => "bib0120"
              "etiqueta" => "24"
              "referencia" => array:1 [
                0 => array:1 [
                  "referenciaCompleta" => "Mart&#237;nez-Gonz&#225;lez MA&#44; Buil-Cosiales P&#44; Corella D&#44; Bull&#243; M&#44; Fit&#243; M&#44; Vioque J&#44; et al&#46; Cohort Profile&#58; Design and methods of the PREDIMED-Plus randomized trial&#46; Int J Epidemiol&#46; 2018 Nov 22&#46; doi&#58; 10&#46;1093&#47;ije&#47;dyy225&#46;&#91;Epub ahead of print&#93;&#46;"
                ]
              ]
            ]
            24 => array:3 [
              "identificador" => "bib0125"
              "etiqueta" => "25"
              "referencia" => array:1 [
                0 => array:1 [
                  "referenciaCompleta" => "Salas-Salvad&#243; J&#44; D&#237;az-L&#243;pez A&#44; Ruiz-Canela M&#44; Basora J&#44; Fit&#243; M&#44; Corella D&#44; et al&#46; Effect of a lifestyle intervention program with energy-restricted Mediterranean diet and exercise on weight loss and cardiovascular risk factors&#58; One-year results of the PREDIMED-Plus trial&#46; Diabetes Care&#46; 2018 Nov 2&#46; pii&#58; dc180836&#46; doi&#58; 10&#46;2337&#47;dc18-0836&#46;&#91;Epub ahead of print&#93;&#46;"
                ]
              ]
            ]
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ISSN: 25299123
Idioma original: Español
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