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Cribado con doppler de las arterias uterinas para la predicción de complicaciones de la gestación
J. Arenasa, J. Fernández-iñareaa, C. Rodríguez-mona, B. Dupláa, E. Díeza, A. González-garcíaa
a Servicio de Obstetricia y Ginecología. Hospital de Cabueñes. Gijón. Asturias. España
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        "resumen" => "<p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">The role of uterine artery Doppler in the prediction of pre-eclampsia and uterine growth retardation has been known since the middle of the 1980s&#44; but as yet it does not have a definitive place in obstetric practice&#46;</p><p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">With the aim of assessing its value as a screening&#46; test for these pathologies a prospective study of 319 pregnancies in an unselected population in the 20th week of pregnancy was made&#46; The parameter of the impedance to flow was the mean resistance index for the two uterine arteries with different cut-off levels&#46;The prevalence of pre-eclampsia was 3&#46;44&#37;&#44; growth retardation 8&#46;15&#37;&#44; and of premature birth 6&#46;89&#37;&#46;</p><p id="spar0015" class="elsevierStyleSimplePara elsevierViewall">For a resistance index &#8805; 0&#46;59 &#40;P-75&#41; the following results are obtained&#58;</p><p id="spar0020" class="elsevierStyleSimplePara elsevierViewall"><span class="elsevierStyleItalic">1</span>&#46; Prediction of pre-eclampsia&#58; sensitivity&#44; 72&#46;7&#37;&#59; specifity&#44; 73&#46;7&#37;&#59; predictive value of positive tests&#44; 8&#46;98&#37;&#59; predictive value of negative tests&#44; 98&#46;6&#37;&#59; odds ratio&#44; 7&#46;47 &#40;1&#46;74-36&#46;51&#41;&#46;</p><p id="spar0025" class="elsevierStyleSimplePara elsevierViewall"><span class="elsevierStyleItalic">2</span>&#46; Prediction of foetal growth retardation&#58; sensitivity&#44; 46&#46;15&#37;&#59; specificity&#44; 73&#46;72&#37;&#59; predictive value of positive tests&#44; 13&#46;48&#37;&#59; predictive value of negative tests&#44; 93&#46;1&#37;&#59; odds ratio&#44; 2&#46;40 &#40;1&#46;31-8&#46;97&#41;&#46;</p><p id="spar0030" class="elsevierStyleSimplePara elsevierViewall"><span class="elsevierStyleItalic">3</span>&#46; Prediction of premature birth&#58; sensitivity&#44; 54&#46;54&#37;&#59; specificity&#44; 74&#46;07&#37;&#59; predictive value of positive tests&#44; 13&#46;48&#37;&#59; predictive value of negative test&#44; 95&#46;65&#37;&#59; odds ratio&#44; 3&#46;42 &#40;1&#46;31-8&#46;97&#41;&#46;</p><p id="spar0035" class="elsevierStyleSimplePara elsevierViewall">Its routine use as a screening test is proposed&#44; makinguse of the routine ultrasound scan at 20 weeks&#46;</p>"
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        "resumen" => "<p id="spar0040" class="elsevierStyleSimplePara elsevierViewall">El papel del Doppler de las arterias uterinas en la predicci&#243;n de preeclampsia y crecimiento intrauterino restringido se conoce desde mediados de la d&#233;cada de 1980&#44; pero a&#250;n no ha encontrado un lugar definitivo en la pr&#225;ctica obst&#233;trica&#46;</p><p id="spar0045" class="elsevierStyleSimplePara elsevierViewall">Con el prop&#243;sito de evaluar su utilidad como prueba de cribado para estas patolog&#237;as&#44; se realiz&#243; un estudio prospectivo en una poblaci&#243;n no seleccionada de 319 gestantes en la semana 20&#46; El par&#225;metro de medida de la impedancia al flujo fue el &#237;ndice de resistencia medio para las dos arterias uterinas utilizando diferentes niveles de corte&#46; La prevalencia de preeclampsia fue del 3&#44;44&#37;&#44; la de crecimiento intrauterino restringido del 8&#44;15&#37; y la de parto pret&#233;rmino del 6&#44;89&#37;&#46;</p><p id="spar0050" class="elsevierStyleSimplePara elsevierViewall">Para un &#237;ndice de resistencia &#8805; 0&#44;59 &#40;percentil 75&#41; se obtienen los siguientes resultados&#58;</p><p id="spar0055" class="elsevierStyleSimplePara elsevierViewall"><span class="elsevierStyleItalic">1</span>&#46; Predicci&#243;n de preeclampsia&#58; sensibilidad del 72&#44;7&#37;&#59; especificidad del 73&#44;7&#37;&#59; valor predictivo positivo &#40;VPP&#41; del 8&#44;98&#37;&#59; valor predictivo negativo &#40;VPN&#41; del 98&#44;6&#37;&#44; y <span class="elsevierStyleItalic">odds ratio</span> &#40;OR&#41; de 7&#44;47 &#40;intervalo de confianza &#91;IC&#93;&#44; 1&#44;74-36&#44;51&#41;&#46;</p><p id="spar0060" class="elsevierStyleSimplePara elsevierViewall"><span class="elsevierStyleItalic">2</span>&#46; Predicci&#243;n de CIR&#58; sensibilidad del 46&#44;15&#37;&#59; especificidad del 73&#44;72&#37;&#59; VPPdel 13&#44;48&#37;&#59; VPN del 93&#44;1&#37;&#44; y OR de 2&#44;40 &#40;IC del 95&#37;&#44; 0&#44;99-5&#44;81&#41;&#46;</p><p id="spar0065" class="elsevierStyleSimplePara elsevierViewall"><span class="elsevierStyleItalic">3</span>&#46; Predicci&#243;n de parto pret&#233;rmino&#58; sensibilidad del 54&#44;54&#37;&#59; especificidad del 74&#44;07&#37;&#59; VPP del 13&#44;48&#37;&#59; VPN del 95&#44;65&#37;&#44; y OR de 3&#44;42 &#40;IC de 95&#37;&#44; 1&#44;31-8&#44;97&#41;&#46;</p><p id="spar0070" class="elsevierStyleSimplePara elsevierViewall">Se propone su uso habitual como prueba de cribado aprovechando la ecograf&#237;a ordinaria protocolizada de la semana 20&#46;</p>"
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ISSN: 0210573X
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