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Inicio Clínica e Investigación en Ginecología y Obstetricia Feocromocitoma y gestación
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Vol. 29. Núm. 5.
Páginas 181-192 (enero 2002)
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Vol. 29. Núm. 5.
Páginas 181-192 (enero 2002)
Acceso a texto completo
Feocromocitoma y gestación
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9120
A. Tejerizo-Garcíaa, L.C. Tejerizo-Lópeza, A.I. Teijeloa, M.M. Sánchez-Sáncheza, R.M. García-Roblesa, A. Leivaa, J.A. Pérez-Escanillaa, J.M. Benaventea, F. Correderaa, F. Jiménez-Vicente1
1 Servicio de Medicina Interna. Hospital Virgen de la Vega. Salamanca. España.
a Servicio de Obstetricia y Ginecología.
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Información del artículo
Resumen

La asociación feocromocitoma y gestación es rara,lo que explica la dificultad de su diagnóstico, teniendo en cuenta que el feocromocitoma puede manifestarse como una hipertensión arterial gravídica banal.

El pronóstico maternofetal está condicionado porun diagnóstico temprano y la puesta en práctica deuna atención médica multidisciplinaria que prepare laexéresis del tumor. La certidumbre diagnóstica vienedada por los tests biológicos que son simples y fiablesa condición de pensar en el cuadro.

El tumor es localizado por ecografía o por resonancia magnética nuclear. La preparación por bloqueadores alfa permite elegir, en función del término, el momento de extirpar el tumor antes o después del parto. Esta estrategia permite reducir una mortalidad materna y fetal que es muy elevada cuando el diagnósticoes desconocido.

Summary

Phaeochromocytoma is rarely observed during pregnancy, and is not easily diagnosed since the clinical finding may be mild hypertension.

Maternal and foetal prognosis depend on early diagnosis and multidisciplinary management, in preparation for tumour resection. Positive diagnosis is made using simple reliable biological tests, once the condition has been considered.

The tumour is localised using ultrasonography or magnetic resonance imaging. The use of alpha-blockers makes it possible to choice the best resection time, before or after delivery. This strategy reduces maternal and foetal mortality, which is high if the phaeochromocytoma goes undiagnosed.

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Bibliografía
[1.]
J.G. Schlenker, I. Chowers.
Pheochromocytoma and pregnancy. Review of 89 cases.
Obstet Gynecol Surv, 26 (1971), pp. 739-747
[2.]
T.L. Fudge, W.N. Mckinnon, W.L. Geary.
Current surgical management of pheochromocytoma during pregnancy.
Arch Surg, 115 (1980), pp. 1224-1225
[3.]
J.G. Schenker, M. Granat.
Pheochromocytoma and pregnancy. An updated appraisal.
Aust N Z J Obstet Gynecol, 22 (1982), pp. 1-10
[4.]
J.P. Holt.
Alteraciones de las glándulas en el embarazo.
Medicina clínica en obstetricia, pp. 263-293
[5.]
L. Landsberg.
Pheochromocytoma complicating pregnancy.
Eur J Endocrinol, 30 (1994), pp. 2215-2216
[6.]
R. Barhmi, M. El Haddoury, B. Ghrab, A. Elbouhali, R. Tachi-nante, S. Nabil, et al.
Phéochromocytome et grossesse.
J Gynecol Obstet Biol Reprod, 24 (1995), pp. 543-548
[7.]
T.F. Ferris.
Hipertensión y preeclampsia.
Complicaciones médicas durante el embarazo, 4.a, pp. 1-28
[8.]
P.R. Garner.
Trastornos hipofisarios y suprarrenales.
Complicaciones médicas durante el embarazo, 4.a, pp. 187-208
[9.]
V. Castaigne, R. Afriat, S. Cambouris-Perrine, S. Radu, J. Des-dovit, M. Freund.
Association phéochromocytome et gros-sese. A propos de 2 cas et revue de la littérature.
J Gynecol Obstet Biol Reprod, 27 (1998), pp. 622-624
[10.]
L. Landsberg, J.B. Young.
Feocromocitoma.
Harrison. Principios de medicina interna, 14, pp. 2337-2341
[11.]
P.A. Daly, L. Landsberg.
Pheochromocytoma: diagnosis and management.
Baillieres Clin Endocrinol Metab, 6 (1992), pp. 143-166
[12.]
G. Stenström, K. Swolin.
Pheochromocytoma in pregnancy. Experience of treatment with phenoxybenzamine in three patients.
Acta Obstet Gynecol Scand, 64 (1985), pp. 357-361
[13.]
A.G. Juimo, A.S. Dohh, I. Gaggni.
Phéochromocytome et grossesse. A propos d’un cas.
J Radiol, 668 (1987), pp. 643-646
[14.]
C. Avril, P.H. Brouchard.
Phéochromocytome.
Pathologies matternelles et grossesse, pp. 192-193
[15.]
M.E. Molitch.
Phéochromocytome.
Medecine de la femme enceinte, (1990), pp. 130-133
[16.]
R. Doumith, B. Wechsler, Y. Le Charpentier.
Confrontation anatomoclinique.
Ann Med Intern, 143 (1993), pp. 323-327
[17.]
K.L. Melmon.
The endocrinologic function of selected autacoids: Catecholamines, acetylcholine, serotonin, and histamine.
Textbook of endocrinologyl, pp. 515-542
[18.]
A.E. Hendee, R.D. Martin, W.C. Walters.
Hypertension in pregnancy: toxemia or pheochromocytoma?.
Am J Obstest Gynecol, 105 (1989), pp. 64-70
[19.]
W.E. Brenner, S.S.C. yen, J.R. Dingfelder.
Pheocromocytoma: serial studies during pregnancy.
Am J Obstest Gynecol, 113 (1972), pp. 779-788
[20.]
M.I. Griffith, J.H. Felts, F.H. James.
Succesful control of pheochromocytoma in pregnancy.
JAMA, 229 (1974), pp. 437-439
[21.]
M. Greenberg, A.H. Moawad, B.M. Wieties, L.I. Goldberg, E.I. Ka-plan, B. Greenberg, et al.
Extra-adrenal pheochromocyto-ma: detection during pregnancy using MRI.
Radiology, 161 (1982), pp. 475-476
[22.]
J.A. Durham.
A noradrenaline secreting phaechromocytoma complicating pregnancy.
Aust NZ J Obstet Gynaecol, 17 (1977), pp. 53-55
[23.]
Y.N. Bakri, S.E. Ingemansson, A. Ali, S. Parkih.
Pheochromocytoma and pregnancy: report of three cases.
Acta Obs-tet Gynecol Scand, 71 (1992), pp. 301-304
[24.]
D. Rabin, T.J. McKenna.
Clinical endocrinology and metabolism.
Principles and practice, (1982), pp. 430-477
[25.]
R.B. Jaffe, T.S. Harroson, J.C. Cerny.
Localization of metasta-tic pheochromocytoma in pregnancy by caval catheterisation.
Am J Obstest Gynecol, 104 (1969), pp. 939-944
[26.]
E. Paloyan.
Familial pheochromocytoma medullary thyroid carcinoma, and parathyroid adenomas. JAMA.
pp. 1443-1447
[27.]
J. Simanis, J.R. Amerson, A.E. Hendee.
Unresectable pheochromocytoma in pregnancy, pharmacology, and biochemistry.
Am J Med, 53 (1972), pp. 381-385
[28.]
G.T. Ellison, J.A. Mansberger, A.R. Mansberger.
Malignant recurrent pheochromocytoma during pregnancy: case report and review of the literature.
Surgery, 103 (1988), pp. 484-488
[29.]
C.V.S. Ram, K. Engleman, Pheochromocytoma.
Recognition and management.
Problems in current in cardiology. Vol. 4, pp. 1-37
[30.]
B. Shapiro, M.D. Gross.
Endocrine crises. Pheochromocytoma.
Crit Care Clin, 7 (1991), pp. 1-21
[31.]
J.J. Rovinsky.
Disease complicating pregnancy.
Gynecology and obstetrics, pp. 697-729
[32.]
A. Botcham, R. Hauser, M. Kupferminc, D. Grisaru, M.R. Peyser, J.B. Lessing.
Pheochromocytoma in pregnancy: case report and review of the literature.
Obstet Gynecol Surv, 50 (1995), pp. 321-327
[33.]
A.M. Harper, G.A. Murnagham, L. Kennedy, D.R. Hadden, A.B. At-kinson.
Pheochromocytoma in pregnancy. Five cases and review of the literature.
Br J Obstet Gynaecol, 96 (1989), pp. 594-606
[34.]
R.M. Walker.
Phaechromocytoma in relation to pregnancy.
Br J Surg, 51 (1964), pp. 590-595
[35.]
D. Leak, J.J. Carroll, D.C. Robinson, E.J. Assworth.
Management of pheochromocytoma during pregnancy.
Can Med Assoc J, 116 (1977), pp. 371-375
[36.]
M. Bennet, G. Mather.
Phaeochromocytoma and pregnancy.
Lancet, 1 (1959), pp. 811-812
[37.]
J.M. Syigos, E.R. Strasburg.
Phaeochromocytoma and pregnancy.
S Afr Med J, 52 (1977), pp. 496-502
[38.]
A.A. Brown.
Maternal death associated with a paeochro-mocytoma.
J Obstet Gynaecol Br Commonw, 78 (1971), pp. 764-765
[39.]
A.M. Smith.
Phaeochromocytoma and pregnancy.
J Obstet Gynaecol Br Commonw, 80 (1973), pp. 848-851
[40.]
K. Benabed, M. Mohammadi, J. Belkhadir, H. Lachgar.
Pheochromocytoma et grossesse à propos d’un cs [abstract]. Fés (Maroc), Congrès National Medical.
pp. 321
[41.]
PF; Chatellier G Plovin, M.A. Rougeot, J.M. Duclos, J.Y. Pagny, P. Corvol, et al.
Recent developments in pheochromocytoma diagnosis and imaging.
Adv Nephrol, 17 (1988), pp. 275-286
[42.]
R. Venuto, P. Brustein, R. Schneider.
Pheochromocytoma: antepartum diagnosis and management with resection in the puerperium.
Am J Obstet Gynecol, 15 (1984), pp. 431-432
[43.]
L. Landsberg, J.B. Young.
Fisiología y farmacología del sistema nervioso autónomo.
Harrison. Principios de medicina interna. I, 14, pp. 488-501
[44.]
D.T. Freier, F.E. Eckhauser, T.S. Harrison.
Pheochromocytoma. A persistently problematic and potentially lethal disease.
Arch Surg, 115 (1980), pp. 388-391
[45.]
V.L. Katz, T. Jenkins, L. Haley, WA Jr. Bowes.
Catecholamine levels in pregnant physicians and nurses.
Obstet Ginecol, 77 (1991), pp. 338-342
[46.]
J.R. Crout, J.J. Pisano, A. Sjoerdsma.
Urinary excretion of ca-techolamines and their metabolites in pheocromocytoma.
Am heart J, 61 (1961), pp. 375-381
[47.]
J. Axelrod.
Purification and properties of phenylethanolamide N-Methyl transderase.
J Biol Chem, 237 (1962), pp. 1657-1660
[48.]
J.W. Reinig, J.L. Doppman.
Magnetic resonance imaging of the adrenal.
Radiology, 26 (1986), pp. 186-192
[49.]
M. Krempf, J. Lumbroso, R. Mornex, A.J. Brendel, J.L. Wemeau, M.J. Dlisle, et al.
Use of m-(131 I)iodobenzylguanidine in the treatment of malignant pheochromocytoma.
J Clin Endocrinol Metab, 72 (1991), pp. 455-461
[50.]
J.H. Stanley, F. Sánchez, D.G. Frey, S.I. Schabel.
Computed tomography evaluation of pheochromocytoma in pregnancy. J.
Computed Tomogr, 9 (1985), pp. 369-372
[51.]
National Radiological Protection Board..
Revised guidance on acceptable limits of exposure during nuclear magnetic resonance clinical imaging.
Br J Radiol, 56 (1983), pp. 974-977
[52.]
M.C. Powell, B.S. Worthington, J.M. Buckley, E.M. Symonds.
Magnetic resonance imaging (MRI) in obstetrics. I. Maternal anatomy.
Br J Obstet Gynaecol, 95 (1988), pp. 31-37
[53.]
E. Kanal.
An overview of electromagnetic safety considerations associated with magnetic resonance imaging.
Ann NY Acad Sci, 649 (1992), pp. 204-224
[54.]
M. Palot, A. Burde, C. Quéreux, J.B. Flament, H. Grulet.
Anesthésie pour césarienne et exérèse d’un phéochromocytome dû au syndrome de Sipple.
Ann Franesth Réanim, 10 (1991), pp. 84-87
[55.]
C. Ponte.
Nouveaunés de mères atteintes d’endocrinopathies.
Pédiatrie, 44 (1989), pp. 603-611
[56.]
T.R. Easterling, K. Carlsn, TJ. Mancuso JJ. Benedetti.
Hemodynamics associated with the diagnosis and treatment of pheocromocytoma in pregnancy.
Am J Perinatol, 9 (1992), pp. 464-466
[57.]
H.R. Keiser, M.A. Beaven, J. Doppman, S Jr Well, L.M. Buja.
Sipple’s syndrome: medullary thyroid carcinoma, pheochro-mocytoma and parathyroid disease. Studies in a large family.
Ann Intern Med, 78 (1973), pp. 561-579
[58.]
T.W. Valk, L.S. Frager, M.D. Gross, J.C. Sisson, D.M. Wieland, D.I. Swanson, et al.
Spectrum of pheochromocytoma in multiple endocrine neoplasia.
Ann Intern Med, 94 (1981), pp. 762-767
[59.]
C.M. Chodankar, SC Deodhar KP Abhyankar, A.M. Shanbhag.
Sipple’s syndrome (multiple endocrine neoplasia) in pregnancy. Case report.
Aust NZ J Obstet Gynaecol, 22 (1982), pp. 243-244
[60.]
B. Shapiro, L.M. Fig.
The management of pheochromocyto-ma.
Medical therapy of endocrine tumors. Endocrinol Metab Clin North Am, pp. 443-492
[61.]
C.J. Falterman, R. Kreisberg.
Pheochromocytoma: clinical, diagnosis and management.
South Med J, 75- (1982), pp. 321-328
[62.]
S. Cambouris-Perrine.
Phéochromocytome et grossesse: à propos d’un cas et revue de la literature [tesis doctoral].
[63.]
M.H. Wheeler, M.J.B. Chare, T.R. Austin, J.H. Lazarus.
The management of the patient with catecholamine excess.
World J Surg, 6 (1982), pp. 735-747
[64.]
G.E. Burgess.
Alpha blockade and surgical intervention of pheochromocytoma in pregnancy.
Obstet Gynecol, 53 (1979), pp. 266-270
[65.]
R. Afriat, A. Villeneuve, F. Maitre, E. Bardaxoglou, J.P. Maurel, D. Grossetti.
Phéochromocytome du ligament large.
J Gynecol Obstet Biol Reprod, 22 (1993), pp. 383-384
[66.]
S.A. Awitti-Sunga, W. Ursell.
Phaechromocytoma in pregnancy. Case report.
Br J Obstet Gynaecol, 82 (1975), pp. 426-428
[67.]
G.B. Coombes.
Pheochromocytoma presenting in pregnancy.
Proc R Soc Med, 69 (1976), pp. 224-225
[68.]
I.M. Modlin, J.R. Farndon, A. Shepherd.
Phaechromocytoma in 72 patients: clinical and diagnosis features, treatment and long term results.
Br J Surg, 66 (1979), pp. 456-465
[69.]
T.K. Chatterjee.
Phaechromocytoma in pregnancy: report of two cases and review of the literature.
Med J Zambia, 11 (1978), pp. 167-169
[70.]
B Jr. Brown.
Anesthetic management of endocrine emergencies. Annual Refresher Course Lectures [abstract]. Am Soc Anesthesiol.
pp. 224
[71.]
E.J. Ross, B.N.C. Pritchard, L. Kaufman.
Preoperative and operative management of patients with pheochromocytoma.
BMJ, 1 (1967), pp. 191-198
[72.]
T.L. Fudge, W.M.P. McKinnon, W.L. Geary.
Current surgical management of pheochromocytoma during pregnancy.
Arch Surg, 115 (1980), pp. 1224-1225
[73.]
C.J. Hull.
Pheochromocytoma diagnosis, preoperative preparation management.
Br J Anaesth, 58 (1986), pp. 1453-1468
[74.]
J. Stouham, C. Wakefield.
Pheochromocytoma in pregnancy. Cesarean section under epidural analgesia.
Anesthesia, 38 (1983), pp. 654-658
[75.]
W.L. Dann, A. Hutchinson, D.P. Crtwright.
Maternal and neonatal reponses to alfantanil administred before induction of general anesthesia for cesarean section.
Br J Anaesth, 59 (1987), pp. 1392-1396
[76.]
T. Arai, Y. Hatano, H. Ishida, K. Mori.
Use of nicardipine in the anesthetic management of pheochromocytoma.
Anesth Analg, 65 (1986), pp. 706-708
[77.]
E.H. Shabanah, V. Tricomi, J.R. Suarz.
Effect of epinephrine onb fetal growth and lenght of gestation.
Surg Gynecol Obstet, 129 (1969), pp. 341-343
[78.]
FC Jr Gress, S.C. Anderson, L.C. King.
Uterine vascular bed: effects of acute hypoxia.
Am J Obstet Gynecol, 113 (1972), pp. 1057-1064
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