covid
Buscar en
Endocrinología y Nutrición
Toda la web
Inicio Endocrinología y Nutrición Feocromocitoma con metástasis vertebral
Información de la revista
Vol. 51. Núm. 10.
Páginas 557-561 (diciembre 2004)
Compartir
Compartir
Descargar PDF
Más opciones de artículo
Vol. 51. Núm. 10.
Páginas 557-561 (diciembre 2004)
Acceso a texto completo
Feocromocitoma con metástasis vertebral
Visitas
5100
D. Peñalver
Autor para correspondencia
dpenalver@hotmail.com

Correspondencia: Dr. D. Peñalver Talavera. Valle Inclán, 14, 3.° A. 28044 Madrid. España
, I. Pavón de paz, T. Montoya, S. Monereo-Megías
Hospital Universitario de Getafe. Getafe. Madrid. España
Este artículo ha recibido
Información del artículo
Resumen
Bibliografía
Descargar PDF
Estadísticas

Pheochromocytoma is a tumour that can recur quite frequently. This can happen after many years of monitoring and it can be either adrenal or extraadrenal. We show the case of a woman of fifty years old who presented a recurrence of her disease in a lumbar vertebrae after being diagnosed and operated of a pheochromocytoma located in the left adrenal nine years ago.

Later she underwent surgery in that level, previously carrying out selective arterial embolization.

We also discusse about the different therapeutics choices and the long-term monitoring of the malignant pheochromocytoma.

Key words:
Pheochromocytoma
Metastases
Vertebra
Malignant

El feocromocitoma es un tumor que recurre con cierta frecuencia. Puede ocurrir tras muchos años de seguimiento, con localización adrenal o extraadrenal.

Presentamos el caso de una mujer de 50 años que, tras haber sido diagnosticada e intervenida de un feocromocitoma localizado en la suprarrenal izquierda, presentó una recurrencia de la enfermedad 9 años después en la zona vertebral lumbar. Posteriormente, se intervino quirúrgicamente en esta zona, previa realización de una embolización arterial selectiva. Se discute también acerca de las diferentes opciones terapéuticas y de seguimiento a largo plazo del feocromocitoma maligno.

Palabras clave:
Feocromocitoma
Metástasis
Vértebra
Maligno
El Texto completo está disponible en PDF
Bibliografía
[1.]
H.P. Neumann, M. Reincke, B.U. Bender, R. Elsner, G. Janetschek.
Preserved adrenocortical function after laparoscopic bilateral adrenal sparing surgery for hereditary pheochromocytoma.
J Clin Endocrinol Metab, 84 (1999), pp. 2608-2610
[2.]
P.F. Plouin, G. Chatellier, I. Fofol, P. Corvol.
Tumor recurrence and hypertension persistence after successful pheochromocytoma operation.
Hypertension, 29 (1997), pp. 1133-1139
[3.]
R.E. Goldstein, J.A. O'Neill, G.W. Holcomb, W.M. Morgan, W.W. Neblett, J.A. Oatos, et al.
Clinical experience over 48 years with pheochromocytoma.
Ann Surg, 229 (1999), pp. 755-764
[4.]
F. Mantero, M. Terzolo, G. Arnaldi, G. Osella, A.M. Masini, A. Ali, et al.
A survey on adrenal incidentaloma in Italy. Study Group on adrenal tumors of the Italian Society of Endocrinology.
J Clin Endocrinol Metabolism, 85 (2000), pp. 637-644
[5.]
G.P. Bernini, M.S. Vivaldi, G.F. Argenio, A. Moretti, M. Sgro, A. Salvetti.
Frequency of pheochromocytoma in adrenal incidentalomas and utility of the glucagon test for diagnosis.
J Endocrinol Invest, 20 (1997), pp. 65-71
[6.]
A.M. Sawka, R. Jaeschke, R.J. Singh, W.F. Young Jr..
A comparison of biochemical tests for pheochromocytoma: measurement of fractioned plasma metanephrines compared with the combination of 24-hour urinary metanephrines and catecholaminas.
J Clin Endocrinol Metab, 88 (2003), pp. 553-558
[7.]
E.L. Bravo, R. Tagle.
Pheochromocytoma: state-of-the-art and future prospects.
J Clin Endocrinol Metab, 24 (2003), pp. 539-553
[8.]
J.P. Baguet, L. Hammer, T. Longo, O. Chabre, J.M. Mallion, N. Sturm, et al.
Circumstances of discovery of phaeochromocytoma: a retrospective study of 41 consecutive patients.
Eur J Endocrinol, 150 (2004), pp. 681-686
[9.]
E.L. Bravo.
Pheochromocytoma: new concepts and future tends.
Kidney Int, 40 (1991), pp. 544-546
[10.]
D.S. Goldstein, G. Eisenhofer, J.A. Flynn, G. Wand, K. Pacak.
Diagnosis and localization of pheochromocytoma.
Hypertension, 43 (2004), pp. 907-910
[11.]
G. Eisenhofer, D.S. Goldstein, M.M. Walther, P. Friberg, J.W.M. Lenders, H.R. Keiser, et al.
Biochemical diagnosis of pheochro-mocytoma: how to distinguish true-from false-positive test results.
J Clin Endocrinol Metab, 88 (2003), pp. 2656-2666
[12.]
I. Ilias, J. Yu, J.A. Carrasquillo, C.C. Chen, G. Eisenhofer, M. Whatley, et al.
Superiority of 6-[18F]-fluorodopamine positron emission tomography versus [131I]-metaiodobenzylguanidine scintigraphy in the localization of metastatic pheochromocytoma.
J Clin Endocrinol Metab, 88 (2003), pp. 4083-4087
[13.]
S.D. Averbuch, C.S. Steakley, R.C. Young, E.P. Gelmann, D.S. Goldstein, R. Stull, et al.
Malignant phaeochromocytoma: effective treatment with a combination of cyclophosphamide, vincristine and dacarbazine.
Ann Intern Med, 109 (1988), pp. 267-273
[14.]
K.C. Loh, P.A. Fitzgerald, K.K. Matthay, P.P.B. Yeo, D.C. Price.
The treatment of malignant pheochromocytoma with iodine-131 metaiodobenzylguanidine (131I-MIBG): a comprehensive review of 116 reported patients.
J Endocrinol Invest, 20 (1997), pp. 648-658
[15.]
A. Hartley, D. Spooner, A.M. Brunt.
Management of malignant phaeochromocytoma: a retrospective review of the use of MIBG and chemotherapy in the west Midlands.
Clin Oncology, 13 (2001), pp. 361-366
[16.]
J. Sisson, B. Shapiro, B. Shulkin, S. Urba, S. Zempel, S. Spaulding.
Treatment of malignant pheochromocytomas with 131-I metaiodobenzylguanidine and chemotherapy.
Am J Clin Oncol, 22 (1999), pp. 364-370
[17.]
R. Nader, B.T. Alford, H.J. Nauta, W. Crow, E. Van Sonnenberg, A.G. Hadjepavlou.
Preoperative embolization and intraoperative cryocoagulation as adjuncts in resection of hypervascular lesions of the thoracolumbar spine.
J Neurosurg Spine, 97 (2002), pp. 294-300
[18.]
J. Chiras, C. Cognard, M. Rose, C. Dessauge, N. Martin, L. Pierot, et al.
Percutaneous injection of an alcoholic embolizing emulsion as an alternative preoperative embolization for spine tumor.
Am J Neuroradiol, 14 (1993), pp. 113-117
[19.]
J. Berkefeld, D. Scale, J. Kirchner, T. Heinrich, J. Kollath.
Hypervascular spinal tumors: influence of the embolization technique on perioperative hemorrhage.
Am J Neuroradiol, 20 (1999), pp. 757-763
Copyright © 2004. Sociedad Española de Endocrinología y Nutrición
Opciones de artículo
es en pt

¿Es usted profesional sanitario apto para prescribir o dispensar medicamentos?

Are you a health professional able to prescribe or dispense drugs?

Você é um profissional de saúde habilitado a prescrever ou dispensar medicamentos