La miositis o miopatía inflamatoria es una manifestación frecuente de la acromegalia, aunque poco estudiada. Se caracteriza por debilidad de predominio proximal que puede acompañarse de dolor muscular. El incremento de las enzimas musculares, la alteración en el electromiograma y la biopsia compatible son hallazgos que apoyan el diagnóstico. Presentamos el caso de una paciente que consultó por debilidad muscular. Los estudios complementarios confirmaron la miositis y, tras descartar otras causas, se llegó al diagnóstico de acromegalia. La miositis como manifestación predominante de una acromegalia es excepcional.
Myositis or inflammatory myopathy is a common but little-studied feature of acromegaly, characterized by predominantly proximal weakness that can be accompanied by muscle pain. Findings supporting a diagnosis of myositis are an increase in muscle enzymes, altered electromyography and characteristic biopsy results. We report the case of a patient who presented with muscle weakness. Complementary investigations revealed myositis and, after other causes were ruled out, a diagnosis of acromegaly was established. Myositis as the main manifestation of acromegaly is exceptional.