Información de la revista
Vol. 53. Núm. 6.
Páginas 363-365 (junio 2006)
Vol. 53. Núm. 6.
Páginas 363-365 (junio 2006)
Editorial
Acceso a texto completo
¿Qué sabemos de la función de la proinsulina en la vida embrionaria?
Visitas
12799
Catalina Hernández-Sánchez
, Alicia Mansilla
Autor para correspondencia
chernandez@cib.csic.es
Correspondencia: Dra. C. Hernández-Sánchez. Centro de Investigaciones Biológicas (CSIC). Ramiro de Maeztu, 9 E. 28040 Madrid. España.
Correspondencia: Dra. C. Hernández-Sánchez. Centro de Investigaciones Biológicas (CSIC). Ramiro de Maeztu, 9 E. 28040 Madrid. España.
Grupo de Factores de Crecimiento en el Desarrollo de Vertebrados. Centro de Investigaciones Biológicas (CSIC). Madrid. España
Este artículo ha recibido
Información del artículo
El Texto completo está disponible en PDF
Bibliografía
[1.]
F.G. Banting, C.H. Best.
The internal secretion of the pancreas.
J Lab Clin Med, 7 (1922), pp. 256-271
[2.]
F. Sanger.
Chemistry of insulin; determination of the structure of insulin opens the way to greater understanding of life processes.
Science, 129 (1959), pp. 1340-1344
[3.]
A.V. Morales, J. Serna, C. Alarcon, E.J. de la Rosa, F. de Pablo.
Role of prepancreatic (pro)insulin and the insulin receptor in prevention of embryonic apoptosis.
Endocrinology, 138 (1997), pp. 3967-3975
[4.]
P.B. Antin, T. Yatskievych, J.L. Dominguez, et al.
Regulation of avian precardiac mesoderm development by insulin and insulin- like growth factors.
J Cell Physiol, 168 (1996), pp. 42-50
[5.]
C. Vicario-Abejon, M.J. Yusta-Boyo, C. Fernandez-Moreno, F. de Pablo.
Locally born olfactory bulb stem cells proliferate in response to insulin-related factors and require endogenous insulin- like growth factor-I for differentiation into neurons and glia.
J Neurosci, 23 (2003), pp. 895-906
[6.]
C. Hernandez-Sanchez, A. Lopez-Carranza, C. Alarcon, E.J. de la Rosa, F. de Pablo.
Autocrine/paracrine role of insulin-related growth factors in neurogenesis: local expression and effects on cell proliferation and differentiation in retina.
Proc Natl Acad Sci U S A, 92 (1995), pp. 9834-9838
[7.]
C. Hernandez-Sanchez, E. Rubio, J. Serna, E.J. de la Rosa, F. de Pablo.
Unprocessed proinsulin promotes cell survival during neurulation in the chick embryo.
Diabetes, 51 (2002), pp. 770-777
[8.]
A. Mansilla, C. Lopez-Sanchez, E.J. de la Rosa, V. Garcia-Martinez, E. Martinez-Salas, F. de Pablo, et al.
Developmental regulation of a proinsulin messenger RNA generated by intron retention.
EMBO Rep, 6 (2005), pp. 1182-1187
[9.]
M. Garcia-de Lacoba, C. Alarcon, E.J. de la Rosa, F. de Pablo, et al.
Insulin/insulin-like growth factor-I hybrid receptors with high affinity for insulin are developmentally regulated during neurogenesis.
Endocrinology, 140 (1999), pp. 233-243
[10.]
C. Hernandez-Sanchez, O. Bartulos, F. De Pablo.
Proinsulin: much more than a hormone precursor in development.
Rev Endocr Metab Disord, 6 (2005), pp. 211-216
[11.]
C. Alarcon, J. Serna, B. Perez-Villamil, G.E. Pollerberg, E. Martinez- Salas, F. de Pablo, et al.
Synthesis and differentially regulated processing of proinsulin in developing chick pancreas, liver and neuroretina.
FEBS Lett, 436 (1998), pp. 361-366
[12.]
C. Hernandez-Sanchez, A. Mansilla, E.J. De la Rosa, et al.
Upstream AUGs in embryonic proinsulin mRNA control its low translation level.
EMBO J, 22 (2003), pp. 5582-5592
[13.]
F. De Pablo, E. Hernandez, F. Collia, J.A. Gomez.
Untoward effects of pharmacological doses of insulin in early chick embryos: through which receptor are they mediated?.
Diabetologia, 28 (1985), pp. 308-313
[14.]
M.R. Loeken.
Current perspectives on the causes of neural tube defects resulting from diabetic pregnancy.
Am J Med Genet C Semin Med Genet, 135 (2005), pp. 77-87
[15.]
A. Garcia-Patterson, L. Erdozain, G. Ginovart, J.M. Adelantado, J.M. Cubero, G. Gallo, et al.
In human gestational diabetes mellitus congenital malformations are related to pre-pregnancy body mass index and to severity of diabetes.
Diabetologia, 47 (2004), pp. 509-514
Copyright © 2006. Sociedad Española de Endocrinología y Nutrición