Información del artículo
Introducción
La enfermedad nodular tiroidea es un problema clínico frecuente. En la actualidad, la citología tiroidea obtenida por punción-aspiración constituye el elemento básico en la aproximación diagnóstica de la patología nodular tiroidea. Sin embargo, en numerosas ocasiones la información que esta técnica ofrece no es concluyente, como en los casos en los que el estudio citológico es sospechoso de malignidad. Sobre esta base, hemos realizado un estudio para conocer los resultados histológicos en nuestra serie de citologías tiroideas sospechosas de malignidad.
Material y métodosSe han estudiado 133 citologías tiroideas sospechosas de malignidad correspondientes a 115 pacientes (97 mujeres y 18 varones, edad media ± DE: 46,1 ± 14,8 años; intervalo: 17–81). Todos los pacientes fueron intervenidos quirúrgicamente obteniéndose un resultado histológico en cada caso.
ResultadosDe las 133 citologías estudiadas, en 33 de ellas (24,8%) el resultado histológico fue de malignidad (13 carcinomas foliculares, 10 carcinomas papilares, 6 carcinomas de células de Hürthle y 4 carcinomas medulares); mientras que en 100 casos (75,2%) fue de benignidad (52 hiperplasias nodulares, 29 adenomas foliculares, 10 tiroiditis de Hashimoto, 8 adenomas de células de Hürthle y un caso de enfermedad de Graves).
ConclusionesNuestros resultados demuestran que hallazgos citológicos indeterminados o sospechosos de malignidad pueden aparecer en una gran variedad de enfermedades tiroideas. La elevada proporción de carcinomas tiroideos encontrada en nuestra serie (24,8%) sugiere que la cirugía debe ser considerada como una alternativa terapéutica de
Palabras clave:
Punción-aspiración con aguja fina
Nódulo tiroideo
Carcinoma de tiroides
Neoplasia folicular
Introduction
Nodular thyroid disease is a common problem in clinical practice. Actually, fine-needle aspiration biopsy has become the principal test in the diagnosis of nodular thyroid disease. However, very often the information offered by this procedure is not definitive as in the cases where the cytologic specimens are suspicious. On this basis, we therefore undertook a study to investigate the histological results in our series of patients with thyroid cytology suspicious for malignancy.
Material and methodsOne hundred and thirty-three suspicious lesion specimens on FNA corresponding to 115 patients were studied (97 females and 18 males, mean age: 46.1 ± 14.8 years, range: 17-81). All cases were operated on and a pathological result was obtained in each case.
ResultsOf the 133 specimens, in thirty-three of them (24.8%) the pathological result was malignant (13 follicular carcinoma, 10 papillary carcinoma, 6 Hürthle cell carcinoma and 4 medullary carcinoma); while in the remaining one hundred (75.2%) the result was benign lesions (52 nodular hyperplasia, 29 follicular adenoma, 10 Hashimoto thyroiditis, 8 Hürthle cell adenoma and 1 case of Graves disease).
ConclusionsCytologic findings indeterminate or suspicious for malignancy can appear in different thyroid conditions. The high percentage of thyroid carcinoma found in our series (24,8%) suggests that the surgery must be considered as a therapeutic option of first line in these cases.
Key words:
Fine-needle aspiration
Thyroid nodule
Thyroid carcinoma
Follicular neoplasia
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