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Inicio Endocrinología y Nutrición Transformación anaplásica tardía de dos bocios multinodulares
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Vol. 53. Núm. 8.
Páginas 515-518 (octubre 2006)
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Vol. 53. Núm. 8.
Páginas 515-518 (octubre 2006)
Notas clínicas
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Transformación anaplásica tardía de dos bocios multinodulares
Late anaplastic transformation of two multinodular goiters
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4478
Elena García Fernández
Autor para correspondencia
elenagarciafer@terra.es

Correspondencia: Dra. E. García Fernández. Servicio de Endocrinología y Nutrición. Hospital Universitario 12 de Octubre. Av. de Córdoba, s/n. 28041 Madrid. España.
, Helena Requejo Salinas, Sharona Azriel Mira, Federico Hawkins Carranza
Servicio de Endocrinología y Nutrición. Hospital Universitario 12 de Octubre. Madrid. España
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El carcinoma anaplásico de tiroides es un tumor muy agresivo con una supervivencia media de 3 a 7 meses. El 50% se desarrolla a partir de bocios multinodulares de larga evolución y el 20-30% coexiste con carcinomas diferenciados. Presentamos los casos de 2 pacientes ancianas con bocio multinodular en seguimiento durante años que sufrieron, de forma brusca, una transformación anaplásica. Ante esta posibilidad, y dado el pronóstico infausto de este tipo de carcinoma, se aconseja realizar un seguimiento de por vida en estos pacientes.

Palabras clave:
Bocio multinodular
Carcinoma anaplásico
Masa cervical

Anaplastic thyroid carcinoma is a highly aggressive tumor with a mean survival of 3-7 months. Up to one half of patients have long-standing multinodular goiter and 20-30% have a coexisting differentiated carcinoma. We present two elderly patients under follow-up for multinodular goiters that suddenly showed anaplastic transformation many years after the initial diagnosis. Given the possibility of malignant transformation and the fatal prognosis of this carcinoma, life-long surveillance of these patients is advisable.

Key words:
Multinodular goiter
Anaplastic thyroid carcinoma
Cervical mass
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Copyright © 2006. Sociedad Española de Endocrinología y Nutrición
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