Estadísticas

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      "titulo" => "Diagnóstico de laboratorio de las micosis invasoras por hongos filamentosos en pacientes inmunodeprimidos"
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    "titulo" => "Estrongiloidiasis: epidemiología, manifestaciones clínicas y diagnóstico. Experiencia en una zona endémica: la comarca de La Safor (Valencia)"
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        "titulo" => "Strongyloidiasis&#58; epidemiology&#44; clinical manifestations and diagnosis&#46; Experience in an endemic area&#58; the region of La Safor &#40;Valencia&#44; Spain&#41;"
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        "resumen" => "Strongyloides stercoralis es un nematodo intestinal con un ciclo vital &#250;nico&#44; capaz de hacer persistir la parasitaci&#243;n durante d&#233;cadas gracias a procesos de autoinfecci&#243;n&#46; En el Servicio de Microbiolog&#237;a del Hospital Francesc de Borja de Gand&#237;a &#40;Valencia&#41; se han diagnosticado m&#225;s de mil casos aut&#243;ctonos en los &#250;ltimos 15 a&#241;os&#44; confirmando que se trata de una zona end&#233;mica&#46; Las estrongiloidiasis aguda y cr&#243;nica suelen cursar asintom&#225;ticas&#44; o se asocian con leves procesos gastrointestinales&#44; cut&#225;neos y respiratorios&#44; pero si se producen deficiencias en el sistema inmunitario del portador&#44; especialmente en la respuesta de tipo celular&#44; se pueden desencadenar fen&#243;menos acelerados de autoinfecci&#243;n y desembocar en un s&#237;ndrome de hiperinfestaci&#243;n&#44; con grav&#237;simas complicaciones que suelen resultar fatales&#46; El diagn&#243;stico etiol&#243;gico directo&#44; basado en el cultivo de heces en placa de agar&#44; ha conseguido&#44; en nuestro laboratorio&#44; una eficacia diagn&#243;stica semejante al m&#233;todo de concentraci&#243;n de Baermann&#44; considerado como referente&#44; si bien en poblaci&#243;n aut&#243;ctona la serolog&#237;a podr&#237;a utilizarse como m&#233;todo de cribado&#44; ya que no se conocen interferencias con otras parasitosis propias de nuestro medio&#46; La mejor opci&#243;n terap&#233;utica para el tratamiento de S&#46; stercoralis es la ivermectina&#44; aunque los problemas de disponibilidad propician que se sustituya por el albendazol con demasiada frecuencia&#46; Recomendamos que&#44; en todas las personas procedentes de zonas end&#233;micas o con antecedentes epidemiol&#243;gicos de riesgo&#44; se descarte la estrongiloidiasis antes de iniciar cualquier terapia inmunosupresora&#46;"
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