Estadísticas

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      "titulo" => "Métodos de valoración de pruebas diagnósticas en Enfermedades Infecciosas y Microbiología Clínica"
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          "titulo" => "Methods of evaluation of diagnostic tests in Enfermedades Infecciosas y Microbiología Clínica"
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      "titulo" => "Prevalencia de la infección por el virus de la inmunodeficiencia humana en drogodependientes atendidos desde 1991 a 1996 en un centro de desintoxicación de Castilla y León"
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          "titulo" => "The prevalence of infection by the human immunodeficiency virus in drug addicts attended in a detoxication center in Castilla and León (Spain) from 1991 to 1996"
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    "titulo" => "Aspergilosis pulmonar necrosante crónica: una forma infrecuente de infección por Aspergillus"
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        "resumen" => "<span class="elsevierStyleBold">Fundamento&#58;</span> La aspergilosis pulmonar necrosante cr&#243;nica es una infecci&#243;n de curso lento y progresivo&#44; causada por microorganismos del g&#233;nero Aspergillus que afecta a pacientes moderadamente inmunodeprimidos&#46; <br/>M&#233;todos&#58; Descripci&#243;n de 3 pacientes con s&#237;ndrome t&#243;xico de semanas o meses de evoluci&#243;n&#44; acompa&#241;ado de infiltrados pulmonares visibles en la radiograf&#237;a y la TC tor&#225;cica&#44; en los cuales se descart&#243; la posibilidad de una tuberculosis pulmonar &#40;investigaci&#243;n en esputo&#44; broncoaspirado&#44; cat&#233;ter de Barlett y punci&#243;n pulmonar transparietal en un caso&#41; y que no respondieron al tratamiento para anaerobios&#46; <br/>Resultados&#58; Los 3 casos &#40;2 varones y una mujer&#41; estaban afectados de una enfermedad respiratoria cr&#243;nica &#40;2 EPOC y un asma&#41;&#46; Un paciente hab&#237;a presentado 2 semanas antes una infecci&#243;n por Nocardia asteroides&#46; En los 3casos se aisl&#243; de los cultivos de las diferentes muestras de secreciones pulmonares A&#46; fumigatus&#46; <br/>Conclusiones&#58; Para el diagn&#243;stico de la aspergilosis pulmonar necrosante cr&#243;nica es indispensable un alto grado de sospecha cl&#237;nica&#46; El diagn&#243;stico diferencial debe realizarse con la tuberculosis y las infecciones por anaerobios&#46; No se debe caer en el error de considerar sistem&#225;ticamente el Aspergillus como saprofito de la v&#237;a a&#233;rea de estos pacientes&#44; cuando no se puede evidenciar la presencia de otros microorganismos causantes de la infecci&#243;n&#46;"
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        "resumen" => "<span class="elsevierStyleBold">Background&#58;</span> Chronic necrotizing pulmonary aspergillosis &#40;CNPA&#41; is a chronic pulmonary infection caused by the genus Aspergillus&#44; which usually involves moderately immunosuppressed patients&#46; <br/>Method&#58; We describe 3 patients with a toxic syndrome that had lasted several weeks or months&#44; with lung infiltrates in the chest X-ray and the CT scan&#46; Mycobacterium tuberculosis could not be isolated from different respiratory smears &#40;sputum&#44; bronchoaspiration&#44; Barlett catheter and pulmonary punction in the third case&#41;&#46; Moreover&#44; there was no response to anaerobic treatment&#46; <br/>Results&#58; All 3 patients were moderately immunosuppressed &#40;2 men were COPD and the woman was an asthmatic patient&#41;&#46; One of the men was being treated for a nocardiosis&#46; In all three cases&#44; A&#46; fumigatus was isolated from de different respiratory smears&#46; <br/> <span class="elsevierStyleBold">Conclusions&#46;</span>&#58; To diagnose a CPNA&#44; a high degree of clinical suspiction is needed&#46; The differential diagnose should be done with pulmonary tuberculosis and anaerobic infections&#46; The presence of a member of the genus Aspergillus in the tracheobronchial secretions of a patient should not be systematically considered a saprofit&#44; specially when other microorganisms can not be isolated"
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