Bacteriemias por Acinetobacter baumannii: características clínicas y pronósticas
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Perea" "autores" => array:8 [ 0 => array:3 [ "nombre" => "Jesús" "apellidos" => "Rodríguez-Baño" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "aff0005" ] ] ] 1 => array:3 [ "nombre" => "Álvaro" "apellidos" => "Pascual" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">b</span>" "identificador" => "aff0010" ] ] ] 2 => array:3 [ "nombre" => "Juan" "apellidos" => "Gálvez" "referencia" => array:2 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "aff0005" ] 1 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">c</span>" "identificador" => "cor0005" ] ] ] 3 => array:3 [ "nombre" => "Miguel" "apellidos" => "Ángel Muniain" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "aff0005" ] ] ] 4 => array:3 [ "nombre" => "M.ª José" "apellidos" => "Ríos" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "aff0005" ] ] ] 5 => array:3 [ "nombre" => "Luis" "apellidos" => "Martínez-Martínez" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">b</span>" "identificador" => "aff0010" ] ] ] 6 => array:3 [ "nombre" => "Ramón" "apellidos" => "Pérez-Cano" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "aff0005" ] ] ] 7 => array:3 [ "nombre" => "Evelio" "apellidos" => "J. Perea" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">b</span>" "identificador" => "aff0010" ] ] ] ] "afiliaciones" => array:2 [ 0 => array:3 [ "entidad" => "Servicio de Medicina Interna, Sección de Enfermedades Infecciosas" "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "aff0005" ] 1 => array:3 [ "entidad" => "Departamento de Microbiología. Hospital Universitario Virgen Macarena. Sevilla. España" "etiqueta" => "<span class="elsevierStyleSup">b</span>" "identificador" => "aff0010" ] ] "correspondencia" => array:1 [ 0 => array:3 [ "identificador" => "cor0005" "etiqueta" => "c" "correspondencia" => "Dr. J. Gálvez. Sección de Enfermedades Infecciosas. Hospital Universitario Virgen Macarena. Avda. Dr. Fedriani, 3. 41071 Sevilla. España" ] ] ] ] "pdfFichero" => "main.pdf" "tienePdf" => true "fechaRecibido" => "2002-10-21" "fechaAceptado" => "2003-02-15" "PalabrasClave" => array:2 [ "es" => array:1 [ 0 => array:4 [ "clase" => "keyword" "titulo" => "Palabras clave" "identificador" => "xpalclavsec205121" "palabras" => array:3 [ 0 => "Acinetobacter baumannii" 1 => "Bacteriemia" 2 => "Infección nosocomial" ] ] ] "en" => array:1 [ 0 => array:4 [ "clase" => "keyword" "titulo" => "Key words" "identificador" => "xpalclavsec205120" "palabras" => array:3 [ 0 => "Acinetobacter baumannii" 1 => "Bacteriemia" 2 => "Nosocomial infection" ] ] ] ] "tieneResumen" => true "resumen" => array:2 [ "es" => array:1 [ "resumen" => "<span class="elsevierStyleSectionTitle">Objetivo</span><p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">Análisis de la incidencia, características clínicas y pronóstico de las bacteriemias por Acinetobacter baumannii</p> <span class="elsevierStyleSectionTitle">Métodos</span><p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">Estudio prospectivo de la cohorte de bacteriemias por A. baumannii detectadas entre enero de 1995 y diciembre de 1998. A. baumannii se identificó según las recomendaciones más recientes</p> <span class="elsevierStyleSectionTitle">Resultados</span><p id="spar0015" class="elsevierStyleSimplePara elsevierViewall">Se incluyeron 133 bacteriemias, todas de adquisición nosocomial. La densidad de incidencia fue de 2,02 episodios/10.000 pacientes-día y descendió a 0,40 episodios/10.000 pacientes-día con la aplicación del programa de control. El 70% de los pacientes estaba o había estado en la unidad de cuidados intensivos. El 85% padecía enfermedades crónicas concomitantes y el 62% un índice de gravedad de Hilf superior a 4. El 78% de las cepas eran multirresistentes y el 28% resistentes a imipenem. La mortalidad atribuible fue del 25,6%. El análisis multivariado mostró que el tratamiento antibiótico inapropiado, el shock séptico y un mayor índice de gravedad de Hilf fueron factores independientes de mal pronóstico</p> <span class="elsevierStyleSectionTitle">Conclusión</span><p id="spar0020" class="elsevierStyleSimplePara elsevierViewall">La bacteriemia por A. baumannii afecta fundamentalmente a pacientes graves sometidos a múltiples procedimientos invasivos, en los que la morbimortalidad puede ser elevada. El tratamiento antimicrobiano inadecuado se asoció, entre otros factores, a un peor pronóstico</p>" ] "en" => array:1 [ "resumen" => "<span class="elsevierStyleSectionTitle">Objective</span><p id="spar0025" class="elsevierStyleSimplePara elsevierViewall">The incidence, clinical features, and prognosis of bacteremia due to Acinetobacter baumannii were investigated</p> <span class="elsevierStyleSectionTitle">Methods</span><p id="spar0030" class="elsevierStyleSimplePara elsevierViewall">Prospective study of all episodes of A. baumanii bacteremia detected during the period of January 1995 to December 1998. A. baumannii was identified using recent standard methods</p> <span class="elsevierStyleSectionTitle">Results</span><p id="spar0035" class="elsevierStyleSimplePara elsevierViewall">A total of 133 episodes of bacteremia due to A. baumannii were studied, all of them nosocomial-acquired. The incidence-density diminished from 2.02 episodes per 10,000 patient-days to 0.40 episodes per 10,000 patient-days after the implementation of a control program. Most of the patients (70%) were, or had been, in the ICU when bacteremia occurred. Some 80% of patients had a chronic illness and 62% had a Hilf’s severity score >4. Among the strains identified, 74% were multidrug-resistant and 28% were imipenem-resistant. Attributable mortality was 25.6%. Multivariate analysis showed that inappropriate antibiotic treatment, septic shock, and high Hilf’s severity score were associated with poorer prognosis</p> <span class="elsevierStyleSectionTitle">Conclusion</span><p id="spar0040" class="elsevierStyleSimplePara elsevierViewall">A. baumannii bacteremia mainly affects severely ill patients who have undergone several invasive procedures, and who may have relevant associated morbidity and mortality. Among other variables, inappropriate antibiotic treatment was a risk factor for increased mortalilty</p>" ] ] "bibliografia" => array:2 [ "titulo" => "Bibliografía" "seccion" => array:1 [ 0 => array:2 [ "identificador" => "bibs0005" "bibliografiaReferencia" => array:43 [ 0 => array:3 [ "identificador" => "bib0005" "etiqueta" => "1." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "The increasing significance of Acinetobacter spp.: The need for control and new agents" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:1 [ 0 => "E. Bergone-Berezéin" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:7 [ "tituloSerie" => "J Hosp Infect" "fecha" => "1995" "volumen" => "30" "numero" => "Suppl" "paginaInicial" => "441" "paginaFinal" => "442" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/7560983" "web" => "Medline" ] ] ] ] ] ] ] ] 1 => array:3 [ "identificador" => "bib0010" "etiqueta" => "2." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Acinetobacter spp. As nosocomial pathogens: Microbiological, clinical and epidemiological features" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:2 [ 0 => "E. Bergone-Berezéin" 1 => "K.J. Towner" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "Clin Microb Rev" "fecha" => "1996" "volumen" => "9" "paginaInicial" => "148" "paginaFinal" => "155" ] ] ] ] ] ] 2 => array:3 [ "identificador" => "bib0015" "etiqueta" => "3." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Bacteremia due to Acinetobacter baumannii: epidemiology, clinical findings and prognostics features" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:6 [ 0 => "J.M. Cisneros" 1 => "M.J. Reyes" 2 => "J. Pachón" 3 => "B. Becerril" 4 => "F.J. Caballero" 5 => "J.L. García-Garmendia" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Clin Infect Dis" "fecha" => "1996" "volumen" => "22" "paginaInicial" => "1026" "paginaFinal" => "1032" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/8783704" "web" => "Medline" ] ] ] ] ] ] ] ] 3 => array:3 [ "identificador" => "bib0020" "etiqueta" => "4." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Mortality due to ventilator-associated pneumonia or colonization with Pseudomonas aeruginosa or Acinetobacter species: Assessment by quantitative culture of samples obtained by protected specimen brush" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:5 [ 0 => "J.Y. Fagon" 1 => "J. Chastre" 2 => "Y. Domart" 3 => "J.L. Trouillet" 4 => "C. Gibert" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Clin Infect Dis" "fecha" => "1996" "volumen" => "23" "paginaInicial" => "538" "paginaFinal" => "542" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/8879777" "web" => "Medline" ] ] ] ] ] ] ] ] 4 => array:3 [ "identificador" => "bib0025" "etiqueta" => "5." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Endemic nosocomial Acinetobacter calcoaceticus bacteraemia. Clinical significance, treatment, and prognosis" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:1 [ 0 => "R.A. Smego" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Arch Intern Med" "fecha" => "1985" "volumen" => "145" "paginaInicial" => "2174" "paginaFinal" => "2179" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/4074029" "web" => "Medline" ] ] ] ] ] ] ] ] 5 => array:3 [ "identificador" => "bib0030" "etiqueta" => "6." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Bacteremia with Acinetobacter species: Risk factors and prognosis in different clinical settings" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:2 [ 0 => "P.A.G. Tilley" 1 => "F.J. Roberts" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Clin Infect Dis" "fecha" => "1994" "volumen" => "18" "paginaInicial" => "896" "paginaFinal" => "900" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/8086549" "web" => "Medline" ] ] ] ] ] ] ] ] 6 => array:3 [ "identificador" => "bib0035" "etiqueta" => "7." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Taxonomy of the genus Acinetobacter with the recognition of Acinetobacter baumannii sp. nov., Acinetobacter haemolyticus sp. nov., Acinetobacter johnsonii sp. nov., and Acinetobacter junii sp. nov. and emendeded descriptions of Acinetobacter calcoaceticus and Acinetobacter lwofii" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:2 [ 0 => "P.J.M. Bouvet" 1 => "P.A.D. Grimont" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "Inter J Sys Bacteriol" "fecha" => "1986" "volumen" => "36" "paginaInicial" => "228" "paginaFinal" => "240" ] ] ] ] ] ] 7 => array:3 [ "identificador" => "bib0040" "etiqueta" => "8." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Bacteremia due to Acinetobacter spp. others than Acinetobacter baumannii" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:4 [ 0 => "H. Seifert" 1 => "A. Strate" 2 => "A. Schultze" 3 => "G. Pulverer" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "Infection" "fecha" => "1994" "volumen" => "6" "paginaInicial" => "379" "paginaFinal" => "385" ] ] ] ] ] ] 8 => array:3 [ "identificador" => "bib0045" "etiqueta" => "9." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Distribution of Acinetobacter species on skin of healthty human" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:4 [ 0 => "J. Berlau" 1 => "H. Aucken" 2 => "H. Malmick" 3 => "T. Pitt" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Eur J Clin Microbiol Infect Dis" "fecha" => "1999" "volumen" => "18" "paginaInicial" => "179" "paginaFinal" => "183" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/10357050" "web" => "Medline" ] ] ] ] ] ] ] ] 9 => array:3 [ "identificador" => "bib0050" "etiqueta" => "10." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Nosocomial bacteremia due to Acinetobacter baumannii. Clinical features, epidemiology, and presdictors of mortality" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:3 [ 0 => "H. Seifert" 1 => "A. Strate" 2 => "G. Pulverer" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "Medicine (Baltimore)" "fecha" => "1995" "volumen" => "74" "paginaInicial" => "340" "paginaFinal" => "349" ] ] ] ] ] ] 10 => array:3 [ "identificador" => "bib0055" "etiqueta" => "11." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:1 [ "titulo" => "American College of Chest Physichians/Society of Critical Care Medicine. Consensus conference committee. Definitions for sepsis and organ failure and guidelines for use of innovative therapies in sepsis" ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Crit Care Med" "fecha" => "1992" "volumen" => "20" "paginaInicial" => "864" "paginaFinal" => "874" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/1597042" "web" => "Medline" ] ] ] ] ] ] ] ] 11 => array:3 [ "identificador" => "bib0060" "etiqueta" => "12." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Gram negative bacteremia I. Etiology and ecology" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:2 [ 0 => "W.R. McCabe" 1 => "G.G. Jackson" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "Crit Care Med" "fecha" => "1992" "volumen" => "110" "paginaInicial" => "847" "paginaFinal" => "855" ] ] ] ] ] ] 12 => array:3 [ "identificador" => "bib0065" "etiqueta" => "13." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Antibiotic therapy for Pseudomonas aeruginosa bacteremia: Outcome correlations in a prospective study of 200 patients" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:6 [ 0 => "M. Hilf" 1 => "V.L. Yu" 2 => "J. Sharp" 3 => "J.J. Zuravleff" 4 => "J.A. Korvick" 5 => "M.M. Muder" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Am J Med" "fecha" => "1989" "volumen" => "87" "paginaInicial" => "540" "paginaFinal" => "546" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/2816969" "web" => "Medline" ] ] ] ] ] ] ] ] 13 => array:3 [ "identificador" => "bib0070" "etiqueta" => "14." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Prospective observational study of Klebsiella bacteremia in 230 patients: Outcome for antibiotic combinations versus monotherapy" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:6 [ 0 => "J.A. Korvicks" 1 => "C.S. Bryan" 2 => "B. Farber" 3 => "T.R. Beam" 4 => "R. Schenfeld" 5 => "R.R. Muder" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "Antimicrob Agents Chemotherapy" "fecha" => "1992" "volumen" => "36" "paginaInicial" => "2639" "paginaFinal" => "2644" ] ] ] ] ] ] 14 => array:3 [ "identificador" => "bib0075" "etiqueta" => "15." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "APACHE II: A severity of disease classification system" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:3 [ 0 => "W.A. Knaus" 1 => "E.A. Draper" 2 => "J.E. Zimmerman" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Crit Care Med" "fecha" => "1985" "volumen" => "13" "paginaInicial" => "818" "paginaFinal" => "829" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/3928249" "web" => "Medline" ] ] ] ] ] ] ] ] 15 => array:3 [ "identificador" => "bib0080" "etiqueta" => "16." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "CDC definitions for nosocomial infections" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:5 [ 0 => "J.S. Garner" 1 => "W.R. Jarvis" 2 => "T.G. Emori" 3 => "T.C. Horan" 4 => "J.M. Hughes" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Am J Infect Control" "fecha" => "1988" "volumen" => "16" "paginaInicial" => "128" "paginaFinal" => "140" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/2841893" "web" => "Medline" ] ] ] ] ] ] ] ] 16 => array:3 [ "identificador" => "bib0085" "etiqueta" => "17." "referencia" => array:1 [ 0 => array:1 [ "referenciaCompleta" => "Rodríguez-Baño J, Ramírez, Santos J, Martínez-Martínez L, Munigin MA, Joyanes P, et al. Risk factors for colonization with Acinetobacter baumannii in the intensive care unit. En: Abstract of the 37th Interscience Conference on Antimicrobial Agents and Chemotherapy (ICAAC), Toronto, Canada, September 28-October 1, 1997 (abstract J-9)" ] ] ] 17 => array:3 [ "identificador" => "bib0090" "etiqueta" => "18." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Epidemiologycal significance of cutaneous, pharyngeal, and digestive tract colonization by multiresistant Acinetobacter baumannii in ICU patients" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:6 [ 0 => "J. Ayats" 1 => "X. Corbella" 2 => "C. Ardanuy" 3 => "M.A. Domínguez" 4 => "A. Ricart" 5 => "J. Liñares" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "J Hosp Infect" "fecha" => "1997" "volumen" => "37" "paginaInicial" => "287" "paginaFinal" => "295" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/9457606" "web" => "Medline" ] ] ] ] ] ] ] ] 18 => array:3 [ "identificador" => "bib0095" "etiqueta" => "19." "referencia" => array:1 [ 0 => array:1 [ "referenciaCompleta" => "National Committee for Clinical Laboratory Standard. Methods for dilution antimicrobial susceptibility test for bacteria that grow aerobically approved standard M7-A5. NCCLS, Wayne. PA 2000" ] ] ] 19 => array:3 [ "identificador" => "bib0100" "etiqueta" => "20." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Delineatio of new proteolytic genospecies in the genus Acinetobacter" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:2 [ 0 => "P.J.M. Bouvet" 1 => "S. Jeajean" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Res Microbiol" "fecha" => "1989" "volumen" => "140" "paginaInicial" => "291" "paginaFinal" => "299" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/2799067" "web" => "Medline" ] ] ] ] ] ] ] ] 20 => array:3 [ "identificador" => "bib0105" "etiqueta" => "21." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Identification of Acinetobacter species" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:2 [ 0 => "R.E. Weaver" 1 => "L.E. Actis" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:4 [ "tituloSerie" => "J Clin Microb" "fecha" => "1994" "volumen" => "32" "paginaInicial" => "1833" ] ] ] ] ] ] 21 => array:3 [ "identificador" => "bib0110" "etiqueta" => "22." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Significado clínico de las bacteriemias por Acinetobacter calcoaceticus" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:2 [ 0 => "J.L. Gómez Garcés" 1 => "M.L. Fernández Guerrero" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "Enf Infecc Microb Clin" "fecha" => "1990" "volumen" => "8" "paginaInicial" => "606" "paginaFinal" => "609" ] ] ] ] ] ] 22 => array:3 [ "identificador" => "bib0115" "etiqueta" => "23." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "The clinical significance of positive blood cultures in the 1990s: A prospective comprehensive of microbiology, epidemiology, and outcome of bacteremia and funguemia in adults" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:6 [ 0 => "M.P. Weinstein" 1 => "M.l. Towns" 2 => "S.M. Quartey" 3 => "S. Mirrett" 4 => "L.G. Reimar" 5 => "G. Parmigiani" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Clin Infect Dis" "fecha" => "1997" "volumen" => "24" "paginaInicial" => "584" "paginaFinal" => "602" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/9145732" "web" => "Medline" ] ] ] ] ] ] ] ] 23 => array:3 [ "identificador" => "bib0120" "etiqueta" => "24." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Analysis of bacteremias: Importance of stratification of microbial susceptibilities by source of patients" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:4 [ 0 => "A.M. Yinnon" 1 => "Y. Schelesinger" 2 => "D. Gabbay" 3 => "B. Rudensky" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "J Infect" "fecha" => "1997" "volumen" => "35" "paginaInicial" => "17" "paginaFinal" => "23" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/9279719" "web" => "Medline" ] ] ] ] ] ] ] ] 24 => array:3 [ "identificador" => "bib0125" "etiqueta" => "25." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Six-year prospective study of risk and prognostic factors in patients with nosocomial sepsis caused by Acinetobacter baumannii" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:6 [ 0 => "J. Gómez" 1 => "E. Simarro" 2 => "V. Baños" 3 => "L. Requena" 4 => "J. Ruiz" 5 => "F. García" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Eur J Clin Microbiol Infect Dis" "fecha" => "1999" "volumen" => "18" "paginaInicial" => "358" "paginaFinal" => "361" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/10421044" "web" => "Medline" ] ] ] ] ] ] ] ] 25 => array:3 [ "identificador" => "bib0130" "etiqueta" => "26." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Nosocomial bloodstream infections caused by Acinetobacter species in united States Hospitals: Clinical features, molecular epidemiology, and antimicrobial susceptibility" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:6 [ 0 => "H. Wisplinghoff" 1 => "M.B. Edmond" 2 => "M.A. Pfaller" 3 => "R.N. Jones" 4 => "R.P. Wenzel" 5 => "H. Seifert" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1086/314040" "Revista" => array:6 [ "tituloSerie" => "Clin Infect Dis" "fecha" => "2000" "volumen" => "31" "paginaInicial" => "690" "paginaFinal" => "697" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/11017817" "web" => "Medline" ] ] ] ] ] ] ] ] 26 => array:3 [ "identificador" => "bib0135" "etiqueta" => "27." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Jarvis WR and the National Nosocomial Infections Surveillance System. Seasonal variatio of Acinetobacter infections: 1987-1996" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:2 [ 0 => "L.C. McDonald" 1 => "S.N. Banerje" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1086/313441" "Revista" => array:6 [ "tituloSerie" => "Clin Infect Dis" "fecha" => "1999" "volumen" => "29" "paginaInicial" => "1133" "paginaFinal" => "1137" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/10524953" "web" => "Medline" ] ] ] ] ] ] ] ] 27 => array:3 [ "identificador" => "bib0140" "etiqueta" => "28." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Risk factors, clinical features and outcome of Acinetobacter bacteremia in adults" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:3 [ 0 => "S.M. Poutanen" 1 => "M. Loui" 2 => "A.E. Simor" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "Eur J Clin Microb Infect Dis" "fecha" => "1997" "volumen" => "16" "paginaInicial" => "737" "paginaFinal" => "740" ] ] ] ] ] ] 28 => array:3 [ "identificador" => "bib0145" "etiqueta" => "29." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Risk factors for Acinetobacter baumannii nosocomial bacteremia in critically ill patients: a cohort study" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:6 [ 0 => "J.L. García-Garmendia" 1 => "C. Ortiz-Leyba" 2 => "J. Garnacho-Montero" 3 => "F.J. Jiménez-Jiménez" 4 => "C. Paredes-Paredes" 5 => "A.E. Barrero-Almodóvar" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1086/322584" "Revista" => array:6 [ "tituloSerie" => "Clin Infect Dis" "fecha" => "2001" "volumen" => "33" "paginaInicial" => "939" "paginaFinal" => "946" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/11528563" "web" => "Medline" ] ] ] ] ] ] ] ] 29 => array:3 [ "identificador" => "bib0150" "etiqueta" => "30." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Colonization by Acinetobacter baumannii in intensive-care patients" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:5 [ 0 => "O. Lortholary" 1 => "J.Y. Fagon" 2 => "A.B. Hoi" 3 => "G. Mahieu" 4 => "L. Gutman" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Infect Control Hosp Epidemiol" "fecha" => "1998" "volumen" => "19" "paginaInicial" => "188" "paginaFinal" => "190" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/9552188" "web" => "Medline" ] ] ] ] ] ] ] ] 30 => array:3 [ "identificador" => "bib0155" "etiqueta" => "31." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Relelevance of digestive tract colonization in the epidemiology of nosocomial infections due to multirresistant Acinetobacter baumanni" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:6 [ 0 => "X. Corbella" 1 => "M. Pujol" 2 => "J. Ayats" 3 => "M. Sendra" 4 => "C. Ardanuy" 5 => "M.A. Domínguez" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Clin Infect Dis" "fecha" => "1996" "volumen" => "23" "paginaInicial" => "329" "paginaFinal" => "334" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/8842272" "web" => "Medline" ] ] ] ] ] ] ] ] 31 => array:3 [ "identificador" => "bib0160" "etiqueta" => "32." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Risk factors for nosocomial bloodstream infections due to Acinetobacter baumannii: case-control study of adult burn patients" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:3 [ 0 => "H. Wispinghoff" 1 => "W. Perbix" 2 => "H. Seifert" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1086/515067" "Revista" => array:6 [ "tituloSerie" => "Clin Infect Dis" "fecha" => "1999" "volumen" => "28" "paginaInicial" => "59" "paginaFinal" => "66" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/10028073" "web" => "Medline" ] ] ] ] ] ] ] ] 32 => array:3 [ "identificador" => "bib0165" "etiqueta" => "33." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Bacteremia nosocomial por Acinetobacter" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:5 [ 0 => "S. Moreno" 1 => "T. Vivente" 2 => "M. Armas" 3 => "J.C.L. Bernaldo de Quirós" 4 => "Bouza E. Rodríguez-Creixems" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "Enf Infecc Microb Clin" "fecha" => "1990" "volumen" => "8" "paginaInicial" => "606" "paginaFinal" => "609" ] ] ] ] ] ] 33 => array:3 [ "identificador" => "bib0170" "etiqueta" => "34." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Nosocomial bacteremia due to Acinetobacter calcoaceticus" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:3 [ 0 => "R. Raz" 1 => "J. Alroy" 2 => "J.D. Sobel" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Infection" "fecha" => "1982" "volumen" => "10" "paginaInicial" => "168" "paginaFinal" => "171" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/7107014" "web" => "Medline" ] ] ] ] ] ] ] ] 34 => array:3 [ "identificador" => "bib0175" "etiqueta" => "35." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Nosocomial bacteremia due to Acinetobacter baumannii" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:1 [ 0 => "J. Rodríguez-Baño" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "Rev Medical Microbiology" "fecha" => "1999" "volumen" => "10" "paginaInicial" => "67" "paginaFinal" => "77" ] ] ] ] ] ] 35 => array:3 [ "identificador" => "bib0180" "etiqueta" => "36." "referencia" => array:1 [ 0 => array:1 [ "referenciaCompleta" => "Cisneros JM, Martín D, Becerril B, Ortiz-Leyba C, Bernabeu-Wittel M, Prados MT, et al. Attributable mortality of nosocomial Acinetobacter baumannii bacteremia. Toronto, 40th Interscience Conference on Antimicrobial Agents and Chemotherapy (Abstract 1713)" ] ] ] 36 => array:3 [ "identificador" => "bib0185" "etiqueta" => "37." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Worldwide emergence of carbapenem-resistant Acinetobacter spp" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:2 [ 0 => "M. Afzal-Sha" 1 => "D.M. Livermore" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "J Antimicrob Chemother" "fecha" => "1999" "volumen" => "41" "paginaInicial" => "576" "paginaFinal" => "577" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/9630416" "web" => "Medline" ] ] ] ] ] ] ] ] 37 => array:3 [ "identificador" => "bib0190" "etiqueta" => "38." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Effect of sulbactam on infections caused by imipenem-resistant Acinetobacter calcoaceticus biotype anitratus" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:6 [ 0 => "C. Urban" 1 => "E. Go" 2 => "N. Mariano" 3 => "B.J. Berger" 4 => "I. Arraham" 5 => "D. Rubin" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "J Infect Dis" "fecha" => "1993" "volumen" => "167" "paginaInicial" => "448" "paginaFinal" => "451" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/8421178" "web" => "Medline" ] ] ] ] ] ] ] ] 38 => array:3 [ "identificador" => "bib0195" "etiqueta" => "39." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Treatment of multidrug-resistant Acinetobacter baumannii meningitis with ampicilin/sulbactam" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:6 [ 0 => "M.E. Jiménez-Mejías" 1 => "J. Pachón" 2 => "B. Becerril" 3 => "J. Palomino-Nicas" 4 => "A. Rodríguez Cobacho" 5 => "M. Revuelta" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "J Antimicrob Chemother" "fecha" => "1997" "volumen" => "24" "paginaInicial" => "932" "paginaFinal" => "935" ] ] ] ] ] ] 39 => array:3 [ "identificador" => "bib0200" "etiqueta" => "40." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Efficacy of sulbactam alone and in combination with ampicilin in nosocomial infections caused by multirresistant Acinetobacter baumannii" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:6 [ 0 => "X. Corbella" 1 => "J. Ariza" 2 => "C. Ardanuy" 3 => "M. Vuelta" 4 => "F. Tubau" 5 => "M. Sora" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "J Antimicrob Chemother" "fecha" => "1998" "volumen" => "42" "paginaInicial" => "793" "paginaFinal" => "802" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/10052904" "web" => "Medline" ] ] ] ] ] ] ] ] 40 => array:3 [ "identificador" => "bib0205" "etiqueta" => "41." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Intravenous colistin as therapy for nosocomial infections caused by multidrug-resistant Pseudomonas aeruginosa and Acinetobacter baumannii" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:6 [ 0 => "A.S. Levin" 1 => "A.A. Barone" 2 => "Penço J." 3 => "M.V. Santos" 4 => "I.S. Marinho" 5 => "E.A. Arruda" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1086/514732" "Revista" => array:6 [ "tituloSerie" => "Clin Infect Dis" "fecha" => "1999" "volumen" => "28" "paginaInicial" => "1008" "paginaFinal" => "1011" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/10452626" "web" => "Medline" ] ] ] ] ] ] ] ] 41 => array:3 [ "identificador" => "bib0210" "etiqueta" => "42." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Nosocomial respiratory tract infection and colonization with Acinetobacter calcoaceticus: epidemiologic characteristics" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:4 [ 0 => "A.E. Buxton" 1 => "R.L. Anderson" 2 => "D. Werdegard" 3 => "E. Atlas" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Am J Med" "fecha" => "1978" "volumen" => "65" "paginaInicial" => "507" "paginaFinal" => "513" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/362918" "web" => "Medline" ] ] ] ] ] ] ] ] 42 => array:3 [ "identificador" => "bib0215" "etiqueta" => "43." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Nosocomial respiratory tract colonization and infection with aminoglycoside-resistant Acinetobacter calcoaceticus var. anitratus: epidemiologic characteristics and clinical significance" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:5 [ 0 => "J.E. Peacok" 1 => "L. Sorrel" 2 => "F.D. Sottile" 3 => "L.E. Price" 4 => "W.A. Rutala" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "Infect Control Hosp Epidemiol" "fecha" => "1988" "volumen" => "7" "paginaInicial" => "302" "paginaFinal" => "308" ] ] ] ] ] ] ] ] ] ] ] "idiomaDefecto" => "es" "url" => "/0213005X/0000002100000005/v1_201307121319/S0213005X03729309/v1_201307121319/es/main.assets" "Apartado" => array:4 [ "identificador" => "15249" "tipo" => "SECCION" "es" => array:2 [ "titulo" => "Originales" "idiomaDefecto" => true ] "idiomaDefecto" => "es" ] "PDF" => "https://static.elsevier.es/multimedia/0213005X/0000002100000005/v1_201307121319/S0213005X03729309/v1_201307121319/es/main.pdf?idApp=UINPBA00004N&text.app=https://www.elsevier.es/" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0213005X03729309?idApp=UINPBA00004N" ]
| año/Mes | Html | Total | |
|---|---|---|---|
| 2024 Octubre | 34 | 16 | 50 |
| 2024 Septiembre | 55 | 18 | 73 |
| 2024 Agosto | 47 | 21 | 68 |
| 2024 Julio | 53 | 27 | 80 |
| 2024 Junio | 40 | 41 | 81 |
| 2024 Mayo | 46 | 28 | 74 |
| 2024 Abril | 32 | 28 | 60 |
| 2024 Marzo | 55 | 42 | 97 |
| 2024 Febrero | 44 | 29 | 73 |
| 2024 Enero | 66 | 29 | 95 |
| 2023 Diciembre | 58 | 18 | 76 |
| 2023 Noviembre | 63 | 25 | 88 |
| 2023 Octubre | 107 | 62 | 169 |
| 2023 Septiembre | 66 | 20 | 86 |
| 2023 Agosto | 52 | 19 | 71 |
| 2023 Julio | 110 | 127 | 237 |
| 2023 Junio | 90 | 91 | 181 |
| 2023 Mayo | 102 | 29 | 131 |
| 2023 Abril | 70 | 8 | 78 |
| 2023 Marzo | 51 | 14 | 65 |
| 2023 Febrero | 50 | 12 | 62 |
| 2023 Enero | 49 | 7 | 56 |
| 2022 Diciembre | 47 | 20 | 67 |
| 2022 Noviembre | 79 | 6 | 85 |
| 2022 Octubre | 54 | 29 | 83 |
| 2022 Septiembre | 39 | 36 | 75 |
| 2022 Agosto | 66 | 50 | 116 |
| 2022 Julio | 31 | 25 | 56 |
| 2022 Junio | 32 | 29 | 61 |
| 2022 Mayo | 37 | 12 | 49 |
| 2022 Abril | 49 | 19 | 68 |
| 2022 Marzo | 63 | 16 | 79 |
| 2022 Febrero | 66 | 10 | 76 |
| 2022 Enero | 45 | 16 | 61 |
| 2021 Diciembre | 46 | 25 | 71 |
| 2021 Noviembre | 91 | 28 | 119 |
| 2021 Octubre | 88 | 19 | 107 |
| 2021 Septiembre | 66 | 16 | 82 |
| 2021 Agosto | 47 | 20 | 67 |
| 2021 Julio | 34 | 24 | 58 |
| 2021 Junio | 35 | 17 | 52 |
| 2021 Mayo | 47 | 13 | 60 |
| 2021 Abril | 109 | 16 | 125 |
| 2021 Marzo | 52 | 18 | 70 |
| 2021 Febrero | 69 | 21 | 90 |
| 2021 Enero | 62 | 24 | 86 |
| 2020 Diciembre | 47 | 12 | 59 |
| 2020 Noviembre | 45 | 21 | 66 |
| 2020 Octubre | 36 | 12 | 48 |
| 2020 Septiembre | 73 | 39 | 112 |
| 2020 Agosto | 47 | 22 | 69 |
| 2020 Julio | 33 | 9 | 42 |
| 2020 Junio | 35 | 5 | 40 |
| 2020 Mayo | 46 | 34 | 80 |
| 2020 Abril | 53 | 14 | 67 |
| 2020 Marzo | 61 | 15 | 76 |
| 2020 Febrero | 39 | 11 | 50 |
| 2020 Enero | 40 | 21 | 61 |
| 2019 Diciembre | 62 | 50 | 112 |
| 2019 Noviembre | 29 | 26 | 55 |
| 2019 Octubre | 52 | 25 | 77 |
| 2019 Septiembre | 64 | 32 | 96 |
| 2019 Agosto | 59 | 25 | 84 |
| 2019 Julio | 60 | 25 | 85 |
| 2019 Junio | 98 | 59 | 157 |
| 2019 Mayo | 200 | 142 | 342 |
| 2019 Abril | 86 | 83 | 169 |
| 2019 Marzo | 37 | 19 | 56 |
| 2019 Febrero | 48 | 47 | 95 |
| 2019 Enero | 31 | 27 | 58 |
| 2018 Diciembre | 51 | 28 | 79 |
| 2018 Noviembre | 65 | 42 | 107 |
| 2018 Octubre | 90 | 25 | 115 |
| 2018 Septiembre | 46 | 35 | 81 |
| 2018 Agosto | 16 | 89 | 105 |
| 2018 Julio | 21 | 58 | 79 |
| 2018 Junio | 17 | 49 | 66 |
| 2018 Mayo | 22 | 81 | 103 |
| 2018 Abril | 17 | 28 | 45 |
| 2018 Marzo | 31 | 22 | 53 |
| 2018 Febrero | 40 | 11 | 51 |
| 2018 Enero | 36 | 6 | 42 |
| 2017 Diciembre | 31 | 13 | 44 |
| 2017 Noviembre | 70 | 5 | 75 |
| 2017 Octubre | 82 | 12 | 94 |
| 2017 Septiembre | 48 | 16 | 64 |
| 2017 Agosto | 49 | 5 | 54 |
| 2017 Julio | 63 | 14 | 77 |
| 2017 Junio | 67 | 10 | 77 |
| 2017 Mayo | 71 | 13 | 84 |
| 2017 Abril | 84 | 12 | 96 |
| 2017 Marzo | 118 | 11 | 129 |
| 2017 Febrero | 60 | 3 | 63 |
| 2017 Enero | 40 | 5 | 45 |
| 2016 Diciembre | 103 | 9 | 112 |
| 2016 Noviembre | 166 | 9 | 175 |
| 2016 Octubre | 131 | 9 | 140 |
| 2016 Septiembre | 69 | 8 | 77 |
| 2016 Agosto | 50 | 8 | 58 |
| 2016 Julio | 89 | 5 | 94 |
| 2016 Junio | 137 | 16 | 153 |
| 2016 Mayo | 212 | 10 | 222 |
| 2016 Abril | 146 | 7 | 153 |
| 2016 Marzo | 150 | 10 | 160 |
| 2016 Febrero | 87 | 7 | 94 |
| 2016 Enero | 77 | 9 | 86 |
| 2015 Diciembre | 77 | 9 | 86 |
| 2015 Noviembre | 146 | 9 | 155 |
| 2015 Octubre | 128 | 8 | 136 |
| 2015 Septiembre | 105 | 7 | 112 |
| 2015 Agosto | 96 | 2 | 98 |
| 2015 Julio | 94 | 9 | 103 |
| 2015 Junio | 95 | 2 | 97 |
| 2015 Mayo | 105 | 5 | 110 |
| 2015 Abril | 66 | 11 | 77 |
| 2015 Marzo | 118 | 6 | 124 |
| 2015 Febrero | 91 | 2 | 93 |
| 2015 Enero | 48 | 1 | 49 |
| 2014 Diciembre | 56 | 4 | 60 |
| 2014 Noviembre | 55 | 2 | 57 |
| 2014 Octubre | 57 | 3 | 60 |
| 2014 Septiembre | 60 | 1 | 61 |
| 2014 Agosto | 40 | 4 | 44 |
| 2014 Julio | 59 | 4 | 63 |
| 2014 Junio | 56 | 2 | 58 |
| 2014 Mayo | 56 | 1 | 57 |
| 2014 Abril | 42 | 2 | 44 |
| 2014 Marzo | 59 | 1 | 60 |
| 2014 Febrero | 52 | 1 | 53 |
| 2014 Enero | 48 | 2 | 50 |
| 2013 Diciembre | 64 | 2 | 66 |
| 2013 Noviembre | 100 | 3 | 103 |
| 2013 Octubre | 96 | 6 | 102 |
| 2013 Septiembre | 88 | 6 | 94 |
| 2013 Agosto | 81 | 10 | 91 |
| 2013 Julio | 56 | 6 | 62 |
| 2003 Abril | 4500 | 0 | 4500 |
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