Profilaxis de la infección por citomegalovirus en el trasplante renal
Prophylaxis of cytomegalovirus infection in renal transplantation
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"documento" => "article" "crossmark" => 0 "subdocumento" => "fla" "cita" => "Enferm Infecc Microbiol Clin. 2011;29 Supl 6:33-7" "abierto" => array:3 [ "ES" => false "ES2" => false "LATM" => false ] "gratuito" => false "lecturas" => array:2 [ "total" => 4093 "formatos" => array:3 [ "EPUB" => 9 "HTML" => 2660 "PDF" => 1424 ] ] "es" => array:10 [ "idiomaDefecto" => true "titulo" => "Esquemas de prevención de la infección por citomegalovirus: terapia anticipada frente a profilaxis universal" "tienePdf" => "es" "tieneTextoCompleto" => 0 "tieneResumen" => array:2 [ 0 => "es" 1 => "en" ] "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "33" "paginaFinal" => "37" ] ] "titulosAlternativos" => array:1 [ "en" => array:1 [ "titulo" => "Prevention of cytomegalovirus infection: preemptive therapy versus universal prophylaxis" ] ] "contieneResumen" => array:2 [ "es" => true "en" => true ] "contienePdf" => array:1 [ "es" => true ] "autores" => array:1 [ 0 => array:2 [ "autoresLista" => "Elisa Cordero Matía, Óscar Len" "autores" => array:2 [ 0 => array:2 [ "nombre" => "Elisa" "apellidos" => "Cordero Matía" ] 1 => array:2 [ "nombre" => "Óscar" "apellidos" => "Len" ] ] ] ] ] "idiomaDefecto" => "es" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0213005X11700556?idApp=UINPBA00004N" "url" => "/0213005X/00000029000000S6/v1_201305090319/S0213005X11700556/v1_201305090319/es/main.assets" ] "es" => array:12 [ "idiomaDefecto" => true "titulo" => "Profilaxis de la infección por citomegalovirus en el trasplante renal" "tieneTextoCompleto" => 0 "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "38" "paginaFinal" => "41" ] ] "autores" => array:1 [ 0 => array:4 [ "autoresLista" => "José María Aguado, Salvador Gil Vernet" "autores" => array:2 [ 0 => array:4 [ "nombre" => "José María" "apellidos" => "Aguado" "email" => array:1 [ 0 => "jaguadog@medynet.com" ] "referencia" => array:2 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "aff0005" ] 1 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">¿</span>" "identificador" => "cor0005" ] ] ] 1 => array:3 [ "nombre" => "Salvador" "apellidos" => "Gil Vernet" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">b</span>" "identificador" => "aff0010" ] ] ] ] "afiliaciones" => array:2 [ 0 => array:3 [ "entidad" => "Unidad de Enfermedades Infecciosas, Hospital Universitario 12 de Octubre, Madrid, España" "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "aff0005" ] 1 => array:3 [ "entidad" => "Servicio de Nefrología, Hospital Universitario de Bellvitge, L’Hospitalet de Llobregat, Barcelona, España" "etiqueta" => "<span class="elsevierStyleSup">b</span>" "identificador" => "aff0010" ] ] "correspondencia" => array:1 [ 0 => array:3 [ "identificador" => "cor0005" "etiqueta" => "⁎" "correspondencia" => "Autor para correspondencia." ] ] ] ] "titulosAlternativos" => array:1 [ "en" => array:1 [ "titulo" => "Prophylaxis of cytomegalovirus infection in renal transplantation" ] ] "pdfFichero" => "main.pdf" "tienePdf" => true "PalabrasClave" => array:2 [ "es" => array:1 [ 0 => array:4 [ "clase" => "keyword" "titulo" => "Palabras clave" "identificador" => "xpalclavsec138809" "palabras" => array:3 [ 0 => "Citomegalovirus" 1 => "Profilaxis" 2 => "Trasplante renal" ] ] ] "en" => array:1 [ 0 => array:4 [ "clase" => "keyword" "titulo" => "Keywords" "identificador" => "xpalclavsec138810" "palabras" => array:3 [ 0 => "Cytomegalovirus" 1 => "Prophylaxis" 2 => "Renal transplantation" ] ] ] ] "tieneResumen" => true "resumen" => array:2 [ "es" => array:2 [ "titulo" => "Resumen" "resumen" => "<p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">La infección por citomegalovirus (CMV) sigue representando un problema muy importante para los pacientes con trasplante renal y condiciona no sólo enfermedad visceral o síndromes febriles, sino que colabora en el desarrollo de rechazo agudo y fallo crónico del injerto. La profilaxis con valganciclovir ha supuesto un avance muy notable en el control de esta infección, pero todavía se producen casos de infección tardía por CMV, especialmente cuando se utiliza profilaxis universal. La utilización de profilaxis con valganciclovir durante 200 días es más eficaz que la profilaxis durante 100 días, pero no evita por completo este problema. La profilaxis basada en la detección de viremia por CMV (profilaxis anticipada o <span class="elsevierStyleItalic">preemptive therapy</span>) podría evitar el desarrollo de enfermedad por CMV tardía, pero tiene como inconveniente que exige una monitorización más estrecha del paciente, y que no evita el desarrollo de viremia y sus posibles consecuencias a largo plazo. En este artículo se revisan las recomendaciones actuales de profilaxis de la enfermedad por CMV en el trasplante renal.</p>" ] "en" => array:2 [ "titulo" => "Abstract" "resumen" => "<p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">Cytomegalovirus (CMV) infection remains a major problem in renal transplant recipients. CMV produces not only febrile syndromes and/or visceral disease but also contributes to the development of acute rejection and chronic graft failure. Valganciclovir prophylaxis has represented a major advance in controlling this infection, but late CMV infection after prophylaxis can occur, especially when universal prophylaxis is used. The use of valganciclovir prophylaxis for 200 days is more effective than prophylaxis for 100 days but does not completely prevent this problem. Prophylaxis based on the detection of CMV viremia (early prophylaxis or preemptive therapy) may prevent the development of delayed CMV disease, but has the disadvantage of requiring more intensive monitoring of viremia and does not prevent the development of viremia and its potential consequences in the long term. This article reviews current recommendations for prophylaxis of CMV disease in renal transplantation.</p>" ] ] "bibliografia" => array:2 [ "titulo" => "Bibliografía" "seccion" => array:1 [ 0 => array:2 [ "identificador" => "bibs0005" "bibliografiaReferencia" => array:25 [ 0 => array:3 [ "identificador" => "bib1" "etiqueta" => "1." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Cytomegalovirus in solid organ transplant recipients" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:2 [ 0 => "A. Humar" 1 => "D. 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| año/Mes | Html | Total | |
|---|---|---|---|
| 2024 Noviembre | 14 | 2 | 16 |
| 2024 Octubre | 106 | 12 | 118 |
| 2024 Septiembre | 80 | 11 | 91 |
| 2024 Agosto | 51 | 15 | 66 |
| 2024 Julio | 71 | 11 | 82 |
| 2024 Junio | 73 | 22 | 95 |
| 2024 Mayo | 104 | 18 | 122 |
| 2024 Abril | 78 | 15 | 93 |
| 2024 Marzo | 78 | 14 | 92 |
| 2024 Febrero | 140 | 15 | 155 |
| 2024 Enero | 82 | 11 | 93 |
| 2023 Diciembre | 67 | 13 | 80 |
| 2023 Noviembre | 105 | 19 | 124 |
| 2023 Octubre | 145 | 18 | 163 |
| 2023 Septiembre | 92 | 9 | 101 |
| 2023 Agosto | 88 | 10 | 98 |
| 2023 Julio | 101 | 17 | 118 |
| 2023 Junio | 90 | 11 | 101 |
| 2023 Mayo | 97 | 10 | 107 |
| 2023 Abril | 97 | 13 | 110 |
| 2023 Marzo | 137 | 29 | 166 |
| 2023 Febrero | 131 | 19 | 150 |
| 2023 Enero | 104 | 15 | 119 |
| 2022 Diciembre | 87 | 23 | 110 |
| 2022 Noviembre | 117 | 27 | 144 |
| 2022 Octubre | 88 | 38 | 126 |
| 2022 Septiembre | 114 | 44 | 158 |
| 2022 Agosto | 70 | 32 | 102 |
| 2022 Julio | 81 | 16 | 97 |
| 2022 Junio | 64 | 17 | 81 |
| 2022 Mayo | 86 | 29 | 115 |
| 2022 Abril | 104 | 38 | 142 |
| 2022 Marzo | 130 | 27 | 157 |
| 2022 Febrero | 86 | 13 | 99 |
| 2022 Enero | 136 | 29 | 165 |
| 2021 Diciembre | 88 | 31 | 119 |
| 2021 Noviembre | 82 | 18 | 100 |
| 2021 Octubre | 56 | 21 | 77 |
| 2021 Septiembre | 40 | 22 | 62 |
| 2021 Agosto | 48 | 26 | 74 |
| 2021 Julio | 27 | 11 | 38 |
| 2021 Junio | 69 | 22 | 91 |
| 2021 Mayo | 45 | 12 | 57 |
| 2021 Abril | 110 | 41 | 151 |
| 2021 Marzo | 83 | 23 | 106 |
| 2021 Febrero | 40 | 23 | 63 |
| 2021 Enero | 57 | 20 | 77 |
| 2020 Diciembre | 54 | 22 | 76 |
| 2020 Noviembre | 89 | 23 | 112 |
| 2020 Octubre | 74 | 19 | 93 |
| 2020 Septiembre | 39 | 12 | 51 |
| 2020 Agosto | 40 | 12 | 52 |
| 2020 Julio | 45 | 23 | 68 |
| 2020 Junio | 44 | 19 | 63 |
| 2020 Mayo | 66 | 28 | 94 |
| 2020 Abril | 41 | 11 | 52 |
| 2020 Marzo | 35 | 12 | 47 |
| 2020 Febrero | 41 | 10 | 51 |
| 2020 Enero | 51 | 23 | 74 |
| 2019 Diciembre | 31 | 15 | 46 |
| 2019 Noviembre | 38 | 5 | 43 |
| 2019 Octubre | 60 | 21 | 81 |
| 2019 Septiembre | 48 | 17 | 65 |
| 2019 Agosto | 44 | 8 | 52 |
| 2019 Julio | 47 | 39 | 86 |
| 2019 Junio | 47 | 58 | 105 |
| 2019 Mayo | 59 | 96 | 155 |
| 2019 Abril | 80 | 73 | 153 |
| 2019 Marzo | 73 | 39 | 112 |
| 2019 Febrero | 48 | 26 | 74 |
| 2019 Enero | 33 | 22 | 55 |
| 2018 Diciembre | 31 | 26 | 57 |
| 2018 Noviembre | 55 | 46 | 101 |
| 2018 Octubre | 51 | 9 | 60 |
| 2018 Septiembre | 24 | 20 | 44 |
| 2018 Agosto | 19 | 28 | 47 |
| 2018 Julio | 21 | 20 | 41 |
| 2018 Junio | 49 | 14 | 63 |
| 2018 Mayo | 35 | 10 | 45 |
| 2018 Abril | 46 | 10 | 56 |
| 2018 Marzo | 37 | 6 | 43 |
| 2018 Febrero | 26 | 4 | 30 |
| 2018 Enero | 37 | 6 | 43 |
| 2017 Diciembre | 20 | 4 | 24 |
| 2017 Noviembre | 38 | 7 | 45 |
| 2017 Octubre | 45 | 5 | 50 |
| 2017 Septiembre | 39 | 12 | 51 |
| 2017 Agosto | 34 | 5 | 39 |
| 2017 Julio | 38 | 4 | 42 |
| 2017 Junio | 58 | 3 | 61 |
| 2017 Mayo | 74 | 1 | 75 |
| 2017 Abril | 82 | 6 | 88 |
| 2017 Marzo | 62 | 4 | 66 |
| 2017 Febrero | 78 | 1 | 79 |
| 2017 Enero | 57 | 4 | 61 |
| 2016 Diciembre | 54 | 5 | 59 |
| 2016 Noviembre | 66 | 3 | 69 |
| 2016 Octubre | 81 | 5 | 86 |
| 2016 Septiembre | 91 | 15 | 106 |
| 2016 Agosto | 85 | 15 | 100 |
| 2016 Julio | 59 | 6 | 65 |
| 2016 Junio | 60 | 13 | 73 |
| 2016 Mayo | 73 | 13 | 86 |
| 2016 Abril | 47 | 10 | 57 |
| 2016 Marzo | 64 | 14 | 78 |
| 2016 Febrero | 47 | 13 | 60 |
| 2016 Enero | 37 | 15 | 52 |
| 2015 Diciembre | 26 | 16 | 42 |
| 2015 Noviembre | 55 | 6 | 61 |
| 2015 Octubre | 77 | 25 | 102 |
| 2015 Septiembre | 51 | 24 | 75 |
| 2015 Agosto | 57 | 5 | 62 |
| 2015 Julio | 91 | 11 | 102 |
| 2015 Junio | 47 | 13 | 60 |
| 2015 Mayo | 42 | 21 | 63 |
| 2015 Abril | 50 | 12 | 62 |
| 2015 Marzo | 58 | 7 | 65 |
| 2015 Febrero | 48 | 4 | 52 |
| 2015 Enero | 46 | 4 | 50 |
| 2014 Diciembre | 50 | 8 | 58 |
| 2014 Noviembre | 41 | 8 | 49 |
| 2014 Octubre | 49 | 4 | 53 |
| 2014 Septiembre | 32 | 4 | 36 |
| 2014 Agosto | 23 | 3 | 26 |
| 2014 Julio | 42 | 5 | 47 |
| 2014 Junio | 29 | 10 | 39 |
| 2014 Mayo | 41 | 7 | 48 |
| 2014 Abril | 30 | 4 | 34 |
| 2014 Marzo | 20 | 2 | 22 |
| 2014 Febrero | 24 | 1 | 25 |
| 2014 Enero | 38 | 2 | 40 |
| 2013 Diciembre | 31 | 6 | 37 |
| 2013 Noviembre | 56 | 3 | 59 |
| 2013 Octubre | 45 | 5 | 50 |
| 2013 Septiembre | 26 | 3 | 29 |
| 2013 Agosto | 29 | 8 | 37 |
| 2013 Julio | 21 | 9 | 30 |
| 2011 Diciembre | 164 | 0 | 164 |
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