The serum contents of glutathione peroxidase in umbilical cord blood of low born bodyweight babies and normally born bodyweight babies

Abstract

Objective

The research aimed at investigating the diversity of the enzymatic antioxidant serum contents of the glutathione peroxidase in the umbilical cord blood of the low born bodyweight babies and normal born bodyweight babies. This was the cross-sectional study research.

Methods

Samples were taken using the purposive sampling techniques namely the low born body weight baby group and normal born body weight baby group. Each group comprised 20 samples who were then taken blood sample of the umbilical cords having been cut off led to the placenta as much as 3 cc. The examination of the enzymatic antioxidant contents of the glutathione peroxidase serum used ELISA method. The research was conducted for 3 months. The data analysis used Chi-Square test and Mann–Whitney U test.

Results

The research results indicated that there is the significant diversity of the enzymatic antioxidant serum contents of the glutathione peroxidase between the low born bodyweight babies and normal born bodyweight babies with p value 0.001 < 0.05, in which the measurement of the glutathione peroxidase serum content of the low born body weight baby group is 17.24 ± SD 1.52 ng/mL, whereas the normal born body weight baby group is 20.30 ± SD 3.64 ng/mL.

Conclusion

It can be concluded that the average glutathione peroxidase serum content on the low born bodyweight babies is lower than the normal born bodyweight babies.