Información del artículo
Resumen
La estomatitis aftosa récurrente es una patologia oral común que todavía muestra muchos aspectos controvertidos. En este trabajo revisamos los principales aspectos diagnósticos de esta enfermedad, asi como las terapéuticas que se han utilizado en los íltimos tiempos, y sus diferentes niveles de éxito. A pesar de la existencia de algunos tratamientos sintomáticos eficaces, todavía no disponemos de un terapia curativa para esta enfermedad.
Palabras clave:
Estomatitis
aftas
recurrente
Summary
Recurrent aphtous stomatitis is a common oral pathology with a great amount of features in controversy. In this paper we make a review of the principal features for the diagnosis of this disease and of the therapies used in these last years with different degree of success. Although there are some effective treatments to get an improvement of the symptoms, there is not a definitive healing therapy for this disease.
Key words:
Stomatitis
aphtae
recurrent
Laburpena
“Estomatitis aftosa recurrente” deritzon aho patologia arrunta oraindik estabaidagarri diren aspektu asko erakusten dizkigu. Lan honetan gaixotasun honen aspektu diagnostiko garraintsitsuenak, hala nola azken boladan erabili diren terapeutikoak eta beraren exito maila ezberdinak berrikusten ditugu. Nahiz eta tratamendu sintomatiko eraginkor batzuk egon, oraindik es dugu gaixotasun honentzat sendagarria den terapiarik.
Gako hitzak:
estomatitis
aftak
baliatzaile
El Texto completo está disponible en PDF
Referencias bibliográficas
[1.]
Ship J.A..
Recurrent aphtous stomatitisAn update.
Oral Surg Oral Med Oral Pathol Oral Radiol Endod, 81 (1996), pp. 141-147
[2.]
Woo S.B., Sonis S.T..
Recurrent aphtous ulcers: a review of diagnosis and treatment.
J Am Dent Assoc, 127 (1996), pp. 1202-1213
[3.]
Esparza G., Cerero R., Moreno L.A..
Estomatitis aftosa recurrente.
Gac Dent, 104 (2000), pp. 44-52
[4.]
Piantanida E.W., Samlaska C.P..
Recurrent aphtous stomatitis. Oral Surg Oral Med Oral Pathol.
Oral Radiol Endod, 82 (1996), pp. 472
[5.]
Rees T.D., Binnie W.H..
Recurrent aphtous stomatitis.
Dermatol Clin, 21 (1996), pp. 36-47
[6.]
Katz J., Chauschu G., Peretz B..
Recurrent oral ulceration associated with recurrent herpes labialis. Two distinct entities?.
Community Dent Oral Epidemiol, 29 (2001), pp. 260-263
[7.]
Baughman R.A..
Recurrent aphtous stomatitis vs recurrent herpes: do you know the diference?.
J Ala Dent Assoc, 80 (1996), pp. 26-32
[8.]
Greenberg M.S., Brightman V.J., Ship I.I..
Clinical and laboratory differentiation of recurrent intraoral herpes simplex infection following fever.
J Dent Res, 48 (1969), pp. 385-391
[9.]
Helm T.N., Camisa C., Allen C., Lowder C..
Clinical features of Behçet's disease. Report of four cases.
Oral Surg Oral Med Oral Pathol Radiol Endod, 72 (1991), pp. 30-34
[10.]
Sakane T., Takeno M..
Current therapy in Behçet's disease.
Skin Therapy Lett, 5 (2000), pp. 3-5
[11.]
Zouboulois C.C..
Epidemiology of Adamantiades-Behçet's disease.
Ann Med Interne, 150 (1999), pp. 488-498
[12.]
Rogers R.S..
Recurrent aphtous stomatitis in the diagnosis of Behçets disease.
Yonsei Med J, 38 (1997), pp. 370-379
[15.]
Jorizzo J.L., Taylor R.S., Schmaltiesg F.C..
Complex aphtosis: a forme fruste of Behçet's syndrome?.
J Am Acad Dermatol, 13 (1985), pp. 80-84
[16.]
Gurler A., Boybat A., Tursen U..
Clinical manifestations of Behçet's disease: an analysis of 2147 patients.
Yonsei Med J, 38 (1997), pp. 423-427
[17.]
Eldem B., Onur C., Ozen S..
Clinical features of Behcet's disease.
J Pediatr Ophthalmol Strabismus, 35 (1998), pp. 159-161
[19.]
Krause I., Rosen Y., Kaplan I., Milo G., Guedj D., Molad Y., Weinberger A..
Recurrent aphtous stomatitis in Behçet's disease: clinical features and correlation with systemic disease expression and severity.
J Oral Pathol Med, 28 (1999), pp. 193-196
[20.]
Singh A., Thappa D.M., Hamide A..
The spectrum of mucocutaneus manifestations during the evolutionary phases of HIV disease:an emerging indian scenario.
J Dermatol, 26 (1999), pp. 294-304
[21.]
Magalhaes M.G., Bueno D.F., Serra E., Goncalves R..
Oral manifestations of VIH positiva children.
J Clin Pediatr Dent, 42 (2001), pp. 22-59
[22.]
MacPhail L.A., Greenspan D., Greenspan J.S..
Recurrent aphtous ulcers in asociation with HIV infection. Diagnosis and treatment.
Oral Surg Oral Med Oral Pathol Oral Radiol Endod, 73 (1992), pp. 283-288
[23.]
Phelan J.A., Eisig S., Freedman P.D., Newsome N., Klein R.S..
Major aphtous like ulcers in patients with AIDS.
Oral Surg Oral Med Oral Pathol Oral Radiol Endod, 71 (1991), pp. 68-72
[25.]
Muzyka B.C., Glick M..
Major aphtous ulcers in patients with HIV disease.
Oral Surg Oral Med Oral Pathol Oral Radiol Endod, 75 (1993), pp. 76-85
[25.]
MacPhail L.A., Greenspan D., Feigan D.W., Lanette E.T., Greenspan J.S..
Recurrent aphtous ulcers in association with HIV infection. Description of ulcer types and analysis of Tlymphocyte subsets.
Oral Surg Oral Med Oral Pathol Oral Radiol Endod, 71 (1991), pp. 678-683
[26.]
Aprikyan A.A., Dale D.C..
Mutations in the neutrophil elastase gene in cyclic and congenital neutropenia.
Curr Opin Immunol, 13 (2001), pp. 53-58
[27.]
Hirase N., Abe Y., Muta K., Ishihura H., Umemura T., Nawata H., Nishimura H..
Autoimmune neutropenia with cyclic oscillation of neutrophil count after steroid administration.
Int J Hematol, 73 (2001), pp. 346-350
[28.]
Aprikyan A.A., Liles W.C., Rodger E., Jonas M., Chi E.Y., Dale D.C..
Imapired survival of bone marrow hematopoietic progenitor cells in cyclic neutropenia.
Blood, 97 (2001), pp. 147-153
[29.]
Wright D.G., Dale D.C., Fauci A.S., Wolff S.M..
Human cyclic neutropenia: clinical review and lon term follow up patients.
Med, 60 (1981), pp. 1-13
[30.]
Charon J.A., Mergenhagen S.E., Gallin J.L..
Gingivitis and oral ulceration in patients with neutrophil dysfunction.
J Oral Pathol, 14 (1985), pp. 150-155
[31.]
Tursi A., Giorgetti G., Brandimarte G., Rubino E., Lombardi D., Gasbarrini G..
Prevalence and clinical presentation of subclinical/silent celiac disease in adults: an analysis on a 12 year observation.
Hepatogastroenterology, 48 (2001), pp. 462-464
[32.]
Corazza G.R., Gasbarrini G..
Coeliac disease in adults.
Baillieres Clin Gastroenterol, 9 (1995), pp. 329-350
[33.]
Ferguson N.M., Wray D., Carmichael H.A..
Celiac disease with recurrent aphtae.
Gut, 21 (1980), pp. 223-226
[34.]
Veloso F.T., Saleiro J.V..
Small bowel changes in recurrent ulceration of the mouth.
Hepatogastroenterology, 24 (1987), pp. 36-37
[35.]
Pittock S., Drumm B., Flemming P., McDermott M., Imrie C., Flint S., Bourke B..
The oral cavity in Crohn's disease.
J Pediatr, 138 (2001), pp. 767-771
[36.]
Rudolph I., Goldstein F., DiMarino A.J..
Crohn's disease of the esofagus. Three cases and literature review.
Can J Gastroenterol, 15 (2001), pp. 117-122
[37.]
Masumoto T., Iida M., Nakamura S., Hizawa K., Yao T., Fujishima M..
Crohn's disease of aphtous type: serial changes in intestinal lesions.
Br J Radiol, 73 (2000), pp. 1046-1051
[38.]
Sartor R.B..
Current concepts of the etiology and pathogenesis of ulcerative colitis and Crohn's disease.
Gastroenterol Clin North Am, 24 (1995), pp. 475-507
[39.]
Weinstein T.A., Sciubba J.J., Levine J..
Thalidomide for the treatment of oral aphtous ulcers in Crohn's disease.
J Pediatr Gastroenterol Nutr, 28 (1999), pp. 214-216
[40.]
Marshall G.S., Edwards K.M., Butler J., Lawton A.R..
Syndrome of periodic fever, pharyngitis and aphtous stomatitis.
J Pediatr, 100 (1987), pp. 43-46
[41.]
Feder H.M..
Cimetidine treatment for periodic fever associated with aphtous stomatitis, pharyngitis and cervical adenitis.
Pediatr Infect Dis J, 87 (1992), pp. 1-17
[43.]
Feder H.M..
Periodic fever, aphtous stomatitis, pharingitis, adenitis: a clinical review of a new síndrome.
Curr Opin Pediatr, 12 (2000), pp. 253-256
[44.]
Lee W.I., Yang M.H., Lee K.F., Chen L.C., Lin S.J., Yeh K.W., Huang J.L..
PFAPA síndrome (periodic fever, aphtous stomatitis, pharyngitis, adenitis).
Clin Reumatol, 18 (1999), pp. 207-213
[45.]
Thomas K.T., Feder H.M., Lawton A.R., Edwards K.M..
Periodic fever syndrome in children.
J Pediatr, 135 (1999), pp. 15-21
[46.]
Firestein G.S., Gruber H.E., Wisman M.H., Zvailer N.J., Barber J., O'Duffy J.D..
Mouth and genital ulcers with inflamed cartilage: MAGIC syndrome.
Am J Med, 79 (1985), pp. 65-72
[47.]
Imai H., Motegi M., Mizuki N., Ohtani H., Komatsuda A., Hamai K., Miura A.B..
Mouth and genital ulcers with inflamed cartilage (MAGIC síndrome): a case report and literature review.
Am J Med Sci, 314 (1997), pp. 330-332
[48.]
Gamboa F., Rivera J.M., Mayoral L., Grilo A..
Enfermedad de Behçet y policondritis recidivante (syndrome MAGIC) asociado a syndrome antifosfolípido.
Med Clin Barc, 110 (1998), pp. 678-679
[49.]
Fernandez-Monras F., Fornos C., Argimon J., Pujadas R..
Aortitis aneurismática en el sin-drome de MAGIC.
Med Clin Barc, 109 (1997), pp. 684-685
[50.]
Le Thi Huong D., Weschler B., Piette J.C., Papo T., Jaccard A., Jault F., Gandjbakhch I..
Aortic insufficiency and recurrent valva prothesis dehiscence in MAGIC syndrome.
J Reumathol, 20 (1993), pp. 397-398
[51.]
Mignogna M.D., Muzio L.L., Favia G., Ruoppo E., Sammartino G., Zarrelli C., Bucci E..
Oral tuberculosis: a clinical evaluation of 42 cases.
Oral Dis, 6 (2000), pp. 25-30
[52.]
Anil S., Ellepola A.N., Saramanayake L.P., Beena V.T..
Tuberculous ulcer of the tongue as presenting feature of pulmonary tuberculosis and VIH infection.
Gent Dent, 48 (2000), pp. 458-461
[53.]
De Aguiar M.C., Arrais M.J., Mato M.J., De Araujo V.C..
Tuberculosis of the oral cavity: a case report.
Quintessence Int, 28 (1997), pp. 745-747
[54.]
Kolokotronis A., Antoniadis D., Trignonidis G..
Oral tuberculosis.
Oral Dis, 2 (1996), pp. 242-243
[55.]
Gomes-Ferreira O., Vieira-Fernandes A., Sebastiao-Borges A., Simao-Ferreira M., Mota-Loyola A..
Orofacial manifestations of histoplasmosis in HIV positive patients: a cas report.
Med Oral, 6 (2001), pp. 101-105
[56.]
Biclho R.N., Santo M.F., De Aguiar M.C., Santos V.R..
Oral paracoccidiodomycosis: a retrospective study of 62 brazilian patients.
Oral Dis, 7 (2001), pp. 56-60
[57.]
Alamillos-Granados F.J., Dean-Ferrer A., García-Lopez A., Lopez-Rubio F..
Actinomycotic ulcer of the oral mucosa: an unusual presentation of oral actinomycosis.
Br J Oral Maxillofac Surg, 38 (2000), pp. 121-123
[58.]
Piluso S., Ficara G., Lucatorno F.M., Orsi A., Dionisio D., Stenardi L., Eversole L.R..
Cause of oral ulcers in HIV infected patients: a study of 19 cases.
Oral Surg Oral Med Oral Pathol Oral Radiol Endod, 82 (1996), pp. 166-172
[59.]
Shotts R.H., Scully C., Avery C.M., Porter S.R..
Nicorandil-induced severe oral ulceration: a newly recognized drug reaction.
Oral Surg Oral Med Oral Pathol Oral Radiol Endod, 87 (1999), pp. 706-707
[60.]
Gonzalez-Moles M.A., Bag´n J.V..
Alendronate related oral mucosal ulcerations.
J Oral Pathol Med, 29 (2000), pp. 514-518
[61.]
Demerjian N., Bolla G., Spreux A..
Severe oral ulceration induced by alendronate.
Clin Rheumatol, 18 (1999), pp. 349-350
[62.]
Edres MAG, Scully C., Gelbier M..
Use of pro-pietary agents to relieve recurrent aphtous stomatitis.
Br Dent J, 182 (1997), pp. 144-146
[63.]
Vincent S.D., Lilly G.E..
Clinical, historic, and therapeutic features of aphtous stomatitis. Literature review and open clinical trial employing steroids.
Oral Surg Oral Med Oral Pathol Oral Radiol Endod, 74 (1992), pp. 79-86
[64.]
Lozada-Nur F., Huang M.Z., Zhou G.A..
Open preliminary clinical trial of clobetasol propionate oinment in adhesiva paste for treatment of chronic oral vesiculoerosive diseases.
Oral Surg Oral Med Oral Pathol, 71 (1991), pp. 283-287
[65.]
Muzio L.L., Della Valle A., Mignogna M.D., Pannone G., Bucci P., Bucci E., Sciubba J..
The treattment of oral aphtous stomatitis or erosive lichen planus with topical clobetasol propionate in three preparations: a clinical and pilot study on 54 patients.
J Oral Pathol Med, 30 (2001), pp. 611-617
[66.]
Eisen D., Ellis C.N..
Topical clyclosporine for oral mucosal disorders.
J Am Acad Dermatol, 23 (1990), pp. 1259-1263
[67.]
Miles D.A., Bricker S.L., Razmus T.F., Potter R.H..
Triamcinolone acetonide versus chlorhexidine for treatment of recurrent aphtous stomatitis.
Oral Surg Oral Med Oral Pathol, 75 (1993), pp. 397-402
[68.]
Skaare A.B., Herlofson B.B., Barkvoll P..
Mouthrinses containing triclosan reduce the incidence of recurrent aphtous ulcers.
J Clin Periodontol, 23 (1996), pp. 778-781
[69.]
Graykowski E.A., Kingman A.K..
Double-blind trial of tetracycline in recurrent aphtous ulceration.
J Oral Pathol, 7 (1978), pp. 376-382
[70.]
Ylikontiola L., Sorsa T., Harynen Imonnen R., Salo T..
Doxymicine cyanoacrilate treatment of recurrent aphtous ulcers.
Oral Surg Oral Med Oral Pathol Oral Radiol Endod, 83 (1997), pp. 329-333
[71.]
Greer R.O., Lindenmuth J.E., Juarez T., Hhandwala A..
A double blind study of topically applied 5 percent amlexanox in the treatment of aphtous ulcers.
J Oral Maxillofac Surg, 51 (1993), pp. 243-248
[72.]
Eisen D., Lynch D.P..
Selecting topical and systemic agents for recurrent aphtous stomatitis.
Cutis, 68 (2001), pp. 201-206
[73.]
Binnie W.H., Curro F.A., Khandwala A., Van Inwegan I..
Amlexanox oral paste: a novel treatment that accelerates the healing of aphtous ulcers.
Compend Contin Educ Dent, 18 (1997), pp. 1116-1124
[74.]
Collier P.M., Neill S.M., Copeman P.W..
Topical 5-aminosalicylic acid: a treatment for aphtous ulcers.
Br J Dermatol, 126 (1992), pp. 185-188
[75.]
Saxen M.A., Ambrosius W.T., Rehemtula-Al K.F., Russell A.L., Eckert G.J..
Sustained relief of oral aphtous ulcer pain from topical diclofenac in hyaluronan.
Oral Surg Oral Med Oral Pathol Oral Radiol Endod, 84 (1997), pp. 356-361
[76.]
Wu-Wang C.Y., Patel M., Feng J., Milles M., Wang L..
Decreased levels of salivary prostaglandin E2 and epidermal growth factor in recurrent aphtous stomatitis.
Archs Oral Biol, 40 (1995), pp. 1093-1098
[77.]
Taylor L.J., Walker D.M..
A clinical trial of prostaglandin E2 in recurrent aphtous stomatitis.
Br Dent J, 175 (1993), pp. 125-129
[78.]
Donatsky O., Worsaae N., Schiodt M., Johusen T..
Effect of Sendium toothpaste on recurrent aphtous stomatitis.
Scand J Dent Res, 91 (1983), pp. 376-380
[79.]
Hoogendoom H., Piessens J.P..
Treatment of aphtous patients by enhancement of the salivary peroxidase system.
J Oral Pathol Med, 16 (1987), pp. 425-427
[80.]
Rattan J., Schneider M., Arber N., Gorsky M., Dayan D..
Sucralfate suspension as a treatment of recurrent aphtous stomatitis.
J Intern Med, 236 (1994), pp. 341-343
[81.]
Mahdi A.B., Coulter W.A., Woolfson A.D., Lamey P.J..
Efficacy of bioadhesive patches in the treatment of recurrent aphtous stomatitis.
J Oral Pathol Med, 25 (1996), pp. 416-419
[82.]
Wormster G.P., Mack L., Lenox T., et al.
Lack of effect of oral acyclovir on prevention of aphtous stomatitis.
Otolaryngol Head Neck Surg, 98 (1988), pp. 14-17
[83.]
Pedersen A..
Acyclovir in the prevention of severe aphtous ulcers.
Ach Dermatol, 128 (1992), pp. 119-120
[84.]
Dorado C., Chimenos E., Puy D..
Estomatitis aftosa recidivante 2-parte: tratamientos sistémicos.
Rev Eur Odont Estomatol, 6 (1997), pp. 385-392
[85.]
Saenz A, Ausejo M, Shea B, Wells G, Welch V, Tugwell P. Pharmacotherapy for Behçet's syndrome. Cochrane Database Syst Rev 2000;2: CD001084.
[86.]
Wormser G.P., Mack L., Lenox T., Hewlett D., Goldfarb J., Yarrish R.L., Reitano M..
Lack of effect of oral acyclovir on prevention of aphtous stomatitis.
Otolaryngol Head Neck Surg, 98 (1988), pp. 14-17
[87.]
Burgess J.A., Johnson B.D., Sommers E..
Pharmacological management of recurrent oral mucosal ulcerations.
Drugs, 39 (1990), pp. 54-65
[88.]
Torras E..
Tratamiento de la aftosis y de la estomatitis aftosa.
Piel, 8 (1993), pp. 302-305
[89.]
Sanchis J.M., Jimenez Y..
Estomatitis aftosa recidivante: revisión terapéutica.
Oris, 41 (1991), pp. 83-92
[90.]
Sun A., Chinag C.P., Chiang C.P., Chiou P.S., Wang J.T., Liu B.Y., Wu Y.C..
Immunomodulation by levamisole in patients with recurrent aphtous ulcers and oral lichen planus.
J Oral Pathol Med, 23 (1994), pp. 172-177
[91.]
Barrons R.W..
Treatment strategies for recurrent oral aphtous ulcers.
Am J Health Syst Pharm, 58 (2001), pp. 41-53
[93.]
Barnadas M.A..
Aftosis oral recidivante.
Piel, 3 (1986), pp. 111-118
[94.]
Del Rio J., Pozo de la Camara A..
Aftosis crónica recidivante.
Estomodeo, 4 (1984), pp. 123-127
[95.]
Sinz D.E., Kaugars G.E..
Corticoesteroid therapy in general dental practice.
Gen Dent, (1992), pp. 298-300
[96.]
Brown R.S., Bottomley W.K..
Combination immunodepresant a topical steroid therapy for treatment of recurrent major aphtae.
Oral Surg Oral Med Oral Pathol, 69 (1990), pp. 42-44
[97.]
Lozada F., Silverman S., Migliorati C..
Adverse side effects associated with prednisone in the treatment of patients with oral inflammatory ulcerative diseases.
JADA, 109 (1984), pp. 269-270
[98.]
Bousvaros A., Mueller B..
Thalidomide in gastrointestinal disorders.
Drugs, 61 (2001), pp. 777-787
[99.]
Calabrese L., Fleischer A.B..
Thalidomide: current and potential clinical aplications.
Am J Med, 108 (2000), pp. 487-495
[100.]
Ravot E., Lisziewicz J., Liori F..
New uses for old drugs in HIV infection: the role of hydroxyurea, cyclosporin and thalidomide.
Drugs, 58 (1999), pp. 953-963
[101.]
Revuz J., Guillaume J.C., Janier M., Hans P., Marchand C., Souteryand P..
Crossover study of thalidomide vs placebo in severe recurrent aphtous stomatitis.
Arch Dermatol, 126 (1990), pp. 923-927
[102.]
Grinspan D., Fernandez G., Agüeros S..
Treatment of aphtae with thalidomide.
J Am Acad Dermatol, 20 (1989), pp. 1060-1063
[103.]
Jacoson J.M., Greenspan J.S., Splitter J., Ketter N., Fahey J.L., Jacobson J.B., Fox L..
Thalidomide for the treatment of oral aphtous ulcers in patiente with human immunodeficiency virus infection. National Institute of Allergy and Infectious Diseases AIDS Clinical Trials Group.
N Engl J Med, 336 (1997), pp. 1487-1493
[104.]
Ramirez-Amador V.A., Esquivel-Pedraza L., Ponce de Leon S., Reyes-Teran G., Gonzalez-Guevara M., Ponce de Leon S., Sierra-Madero J.C..
Thalidomide as therapy for human immunodeficiency virus-related oral ulcers: a double-blind placebo-controled clinical trial.
Clin Infect Dis, 28 (1999), pp. 892-894
[105.]
Strazzi S., Lebbe C., Geoffray C., Albon G., Morel P., Verola O..
Aphtous ulcers in VIH infected patiens treatment with thalidomide.
Genitourinary Med, 68 (1992), pp. 424-425
[106.]
Paterson D.L., Georghiou P.R., Allworth A.M., Kemp R.J..
Thalidomide as treatment of refractary aphtous ulceration related to human immunodeficiency virus infection.
Clin Infect Dis, 20 (1995), pp. 250-254
[107.]
Gunzler V..
Thalidomide in human immunodeficiency virus (HIV) patients. A review of safety considerations.
Drug Saf, 7 (1992), pp. 116-134
[108.]
Herranz P., Fernandes M.L., De Lucas R., Navarro A.J., Ferrer M., Donado M..
Aftosis oral tipo major en pacientes infectados por el VIH.
Actas Dermosifilog, 85 (1994), pp. 628-632
[109.]
Chandrasekar J., Liem A.A., Cox N.H., Paterso A.W..
Oxypentifilllyne in the management of recurrent aphtous ulcers: an open clinical trial.
Oral Surg Oral Med Oral Pathol Oral Radiol Endod, 87 (1999), pp. 564-567
[110.]
Blanch-Falp J., García-Pont X., Torne-Cachot J., Moner-Coromina L., Baucells-Azcona J.M..
Pentoxifilina y aftosis oral en paciente con infección VIH.
An Med Interna, 14 (1997), pp. 102
[111.]
Garcia Callejo F.J., Orts M.H., et al.
Estomatitis aftosa recurrente y la respuesta clínica a la pentoxifilina.
Acta Otorrinolaringol Esp, 50 (1999), pp. 671-673
[112.]
Pizarro A..
Pentoxifilina: nuevas propiedades y aplicaciones terapéuticas.
Piel, 133 (1993), pp. 659-660
[113.]
Pizarro A., Navarro A..
Tratamiento de un caso de aftosis oral recurrente con pentoxifilina.
Rev Clin Esp, 192 (1993), pp. 96-97
[114.]
Wahba-Yahbah A.V..
Pentoxifillyne in intractable recurrent aphtous stomatitis: An open trial.
J Am Acad Dermatol, 33 (1995), pp. 680-682
[115.]
Pizarro A., Navarro A., Fonseca E., Vidaurrazaga C., Herranz P..
Treatment of rrecurrent aphtous stomatitis with pentoxifillyne.
Br J Dermatol, 133 (1995), pp. 659-660
[116.]
Santos J., Marquez M., Rivero A., Salgado F..
Pentoxifilina en pacientes con SIDA y aftas orales.
Med Clin Barc, 102 (1994), pp. 519
[117.]
Pizarro A., Herranz P., Ferrer M., Casado M..
Aftosis oral recurrente: tratamiento con pentoxifilina.
Med Clin Barc, 6 (1993), pp. 237
[118.]
Ueta E., Osaki T., Yoneda K., Yamamoto T., Kato I..
A clinical trial of azelastine in recurrent aphtous ulceration, with analysis of its actions on leukocytes.
J Oral Pathol Med, 23 (1994), pp. 123-129
[119.]
Bagan J.V., Milina A., Sanchis J.M., Peñarrocha M., Moragon M..
Tratamiento de la estomatitis aftosa recidivante con anapsis: resultados terapéuticos en 20 casos.
Acta Estomatologica Valenciana, 4 (1989), pp. 123-127
[120.]
Hutchinson V.A., Angened J.L., Mok W.L., Cummins J.M., Richards A.B..
Chronic recurrent aphtous stomatitis: oral treatment with low dose interferon alpha.
J Am Acad Dermatol, 12 (1985), pp. 85-90
[121.]
Camacho F., Ortega M., Elorza F..
Glicofosfopeptical en el tratamiento de la aftosis oral recurrente.
An Med Interna, 12 (1995), pp. 204
[122.]
Kaloyannides T.M..
Treatment of recurrent aphtous stomatitis with gammaglobulin: report of five cases.
J Can Dent Assoc, (1971), pp. 277-289
[123.]
Abad F..
Colchicina en aftas orales.
Farmacoterapia, 6 (1997), pp. 314-316
[124.]
Gatot A., Tovi F..
Colchicine therapy in recurrent oral ulcers.
Arch Dermatol, 120 (1984), pp. 994
[125.]
Katz J., Langevitz P., Shemer J..
Prevention of recurrent aphtous stomatitis with colchicine: an open trial.
J Am Acad Dermatol, 31 (1994), pp. 459-461
[127.]
Younger D.S., Mayer S.A., Weimer L.H., et al.
Colchicine induced myopathy and neuropathy.
Neurology, 41 (1991), pp. 943
[128.]
Jaimovich L..
Colchicina: su empleo en dermatología.
Med Cut, 68 (1992), pp. 424-425
[129.]
Izquierdo C., Isante C., Guillén A., Vecino R., Valles C..
Aftosis oral recidivante. Tratamiento con colchicina.
Atencion Primaria, 6 (1989), pp. 35-89
[130.]
Ruah C.B., Stram J.R., Werner D., Chasin M.D..
Treatment of severe recurrent aphtous stomatitis with colchicine.
Arch Otolaryngol Head Neck Surg, 114 (1988), pp. 671-675
[131.]
Velasco E., Machuca G., Martínez A., Rios B., Bullón P..
Influencia de los factores psíquicos sobre la cavidad oral (mecanismos directos).
Arch Odontoestomatol, 10 (1994), pp. 258-270
[132.]
Brice S.L..
Clinical evaluation of the use of low-intensity ultrasound in the treatment of recurrent aphtous stomatitis.
Oral Surg Oral Med Oral Pathol Oral Radiol Endod, 83 (1997), pp. 14-20
Copyright © 2003. Academia de Ciencias Médicas de Bilbao