Estadísticas

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      "titulo" => "Estrategias de cardioprotección en radioterapia"
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        "resumen" => "La cardiotoxicidad despu&#233;s de la terapia sist&#233;mica en pacientes con c&#225;ncer se divide en temprana y tard&#237;a&#46; El mecanismo subyacente no es del todo comprendido&#59; ser&#225; distinto para quimioterapia&#44; radioterapia o para las terapias blanco y el da&#241;o ser&#225; diferente en la infancia o la vejez&#46; La cardiotoxicidad var&#237;a ampliamente y se incrementa de manera muy importante en pacientes ancianos&#46; El riesgo de insuficiencia cardiaca permanece durante el tratamiento y el seguimiento&#46; El da&#241;o cardiaco puede presentarse como entidad subcl&#237;nica&#44; a manera de anormalidades cardiacas en pacientes previamente sanos que han sobrevivido al c&#225;ncer&#44; o como una toxicidad cl&#237;nica&#44; definida con base en los s&#237;ntomas de insuficiencia cardiaca confirmada por estudios diagn&#243;sticos&#46; En este art&#237;culo veremos diferentes estrategias de cardioprotecci&#243;n en oncolog&#237;a y nuevos m&#233;todos de monitoreo de la fracci&#243;n de eyecci&#243;n del ventr&#237;culo izquierdo como el objetivo durante la quimioterapia y algunas terapias blanco&#44; as&#237; como posibles opciones futuras de prevenci&#243;n o tratamiento de la cardiotoxicidad inducida por antraciclinas como el dexrazoxane que previene la generaci&#243;n de radicales libres&#46; Es necesario realizar m&#225;s investigaci&#243;n sobre los inhibidores de la enzima convertidora de angiotensina para revertir el da&#241;o cardiaco y sobre nuevos m&#233;todos diagn&#243;sticos para identificar pacientes con alto riesgo de insuficiencia cardiaca congestiva antes de que el da&#241;o cardiaco se presente&#46;"
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