metricas
covid
Buscar en
Gastroenterología y Hepatología
Toda la web
Inicio Gastroenterología y Hepatología El esófago de Barrett: la realidad biológica de una metaplasia columnar premal...
Información de la revista
Vol. 25. Núm. 4.
Páginas 254-266 (enero 2002)
Compartir
Compartir
Descargar PDF
Más opciones de artículo
Vol. 25. Núm. 4.
Páginas 254-266 (enero 2002)
Acceso a texto completo
El esófago de Barrett: la realidad biológica de una metaplasia columnar premaligna
Visitas
17872
P. Sánchez-Fayos*, M.J. Martín, A. González, O. Bosch, B. Polo, C. Arocena, J.C. Porres
Servicio de Aparato Digestivo. Fundación Jiménez Díaz. Facultad de Medicina. Universidad Autónoma de Madrid
Este artículo ha recibido
Información del artículo
El Texto completo está disponible en PDF
Bibliografía
[1.]
N.R. Barrett.
Chronic peptic ulcer of the aesophagus.
Br J Surg, 38 (1950), pp. 175-182
[2.]
N.R. Barrett.
The lower esophagus lined by columnar epithelium.
Surgery, 41 (1957), pp. 881-894
[3.]
W. Tileston.
Peptic ulcer of esophagus.
Am J Med Sci, 132 (1906), pp. 240-265
[4.]
S.J. Spechler, R.K. Goyal.
Barrett's esophagus.
N Engl J Med, 315 (1986), pp. 362-371
[5.]
S.C. Polepalle, R.W. McCallum.
Barrett's esophagus. Current assessment and future perspectives.
Gastroenterol Clin North Am, 19 (1990), pp. 733-744
[6.]
R.W. Phillips, R.K.H. Wong.
Barrett's esophagus. Natural history, incidence, etiology and complications.
Gastroenterol Clin North Am, 20 (1999), pp. 791-816
[7.]
B.J. Reid.
Barrett's esophagus and esophageal adenocarcinoma.
Gastroenterol Clin North Am, 20 (1991), pp. 7-34
[8.]
S.J. Spechler.
Barrett's esophagus.
Sem in Oncol, 21 (1994), pp. 431-437
[9.]
C.J. Bremner, R.M. Bremner.
Barrett's esophagus.
Surg Clin North Am, 77 (1997), pp. 1115-1137
[10.]
M.B. Fennerty.
Barrett's esophagus: what do we really know about this disease?.
Am J Gastroenterol, 92 (1997), pp. 1-3
[11.]
G.W. Falk, J.E. Richter.
Reflux disease and Barrett's esophagus.
Endoscopy, 30 (1998), pp. 61-72
[12.]
M. Pera, A. Duranceau, A. Pera, J. Rodés, J.R. Malagelada, J.M. Pajares, et al.
Esófago de Barrett.
Enfermedades digestivas Tomo I, pp. 351-365
[13.]
D.O. Castell, D.A. Katzka.
Barrett's esophagus: continuing questions and controversy.
Gastrointest Endosc, 49 (1999), pp. 5-8
[14.]
W. Polkowsky, J.J.B. Van Lanschot, G.J.A. Offerhaus.
Barrett's esophagus and cancer: pathogenesis, carcinogenesis and diagnostic dilemmas.
Histol Histopathol, 14 (1999), pp. 927-944
[15.]
A. Ertan, M. Younes.
Barrett's esophagus.
Dig Dis Sci, 63 (2000), pp. 1670-1673
[16.]
G.B. Salis, J.C. Chiocca, A. García, S. Mazzadi.
Epitelio de Barrett: revisión clínica.
Acta Gastroenterol Latinoamer, 30 (2000), pp. 127-139
[17.]
P. Van Eyken.
Definition of Barrett's esophagus.
Acta Gastrenterol Belg, 63 (2000), pp. 10-12
[18.]
S.J. Spechler.
Barrett's esophagus: an overrated cancer risk factor.
Gastroenterology, 119 (2000), pp. 587-589
[19.]
T.G. Morales, R.E. Sampliner, A. Bhattacharyya.
Intestinal metaplasia of the gastric cardia.
Am J Gastroenterol, 92 (1997), pp. 414-418
[20.]
S.R. De Meester, G.M.R. Campos, T.R. De Meester, C.G. Bremner.
The impact of an antireflux procedure on intestinal metaplasia of the cardia.
Am Surgery, 228 (1998), pp. 547-556
[21.]
J.R. Goldblum, J.J. Vicari, G.W. Falk, T.M. Rice, R.M. Peek, K. Easley.
Inflamation and intestinal metaplasia of the gastric cardia: the role of gastroesofageal reflux and H. pylori infection.
Gastroenterology, 114 (1998), pp. 633-639
[22.]
S.J. Spechler.
The role of gasrtric carditis in metaplasia and neoplasia at the gastroesophageal junction.
Gastroenterology, 117 (1999), pp. 218-228
[23.]
D.A. Kazka.
Barrett's esophagus: detection and management.
Gastroenterol Clin North Am, 18 (1989), pp. 339-357
[24.]
A.T. Prach, T.A. Mac Donald, D.A. Horwood, D.A. Johnston.
Increasing incidence of Barrett's esophagus: education or epidemiology.
Lancet, 350 (1997), pp. 933
[25.]
A.J. Cameron, A.R. Zinsmeister, D.J. Ballard, et al.
Prevalence of columnar-lined (Barrett's) esophagus.
Gastroenterology, 99 (1990), pp. 918-922
[26.]
A.P. Naef, M. Savary, L. Ozzello.
Columnar-lined lower esophagus: an adquired lesion with malignant predisposition.
J Thoracic Cardiovasc Surg, 70 (1975), pp. 826-835
[27.]
A.J. Cameron, B.J. Otto, W.S. Payne.
The incidence of adenocarcinoma in columnarlined (Barrett's) esophagus.
N Engl J Med, 313 (1985), pp. 857-863
[28.]
A.J. Cameron.
Barrett's esophagus and adenocarcinoma: from the family to the gene.
Gastroenterology, 102 (1992), pp. 1421-1424
[29.]
R.C. Haggitt.
Adenocarcinoma in Barett's oesophagus: a new epidemie?.
Human Pathol, 23 (1992), pp. 475-476
[30.]
W.J. Blot, S.S. Devesa, J.F. Fraumeni.
Continuing climb in rates of esophageal adenocarcinoma: an update.
JAMA, 270 (1993), pp. 1320
[31.]
A.J. Cameron, C.T. Lomboy, M. Pera, A. Carpenter.
Adenocarcinoma of the esophagogastric junction and Barrett's esophagus.
Gastroenterology, 109 (1995), pp. 1541-1546
[32.]
D.J. Drowitz, R.E. Sanpliner, H.S. Garewal.
The incidence of adenocarcinoma in Barrett's esophagus: a prospective study of 170 patients followed 4.8 years.
Am J Gastroenterol, 92 (1997), pp. 212-215
[33.]
W. Shahin, J.A. Murray.
Esophageal cancer and Barrett's esophagus.
Postgraduate Medicine, 7 (1999), pp. 111-117
[34.]
W.J. Blot, S.S. Devesa, R.W. Kneller, et al.
Rising incidence of adenocarcinoma of the esophagus and gastric cardia.
JAMA, 265 (1991), pp. 1287-1289
[35.]
G.W. Falk.
Unresolved issues in Barrett's esophagus in the new millenium.
Dig Dis, 18 (2000), pp. 27-42
[36.]
R.E. Sampliner.
Detecting, measuring and managing Barrett's esophagus: the complete endoscopist's dilemma.
Gastrointest Endoscopy, 45 (1997), pp. 533-535
[37.]
H.J. Herlihy, R.O. Orlando, J.C. Bryson, E.M. Bozymski, C.N. Carney.
et al Barrett's esophagus: clinical, endoscopic, histologic, manometric and electrical potential difference characteristics.
Gastroenterology, 86 (1984), pp. 436-443
[38.]
Tytgat GN, Hameeteman W, Onstend R, et al. The spectrum of columnar-lined esophagus (Barrett's esophagus). Endoscopy 189;21:177-85.
[39.]
P.G. Ballinger, W.J. Hogan, A.G. Bohorfoush, et al.
Short segment Barrett's epithelium: prevalence and accuracy of endoscopic detection.
Gastrointest Endoscopy, 39 (1993), pp. 271A
[40.]
S.J. Spechler, J.M. Zeroogian, D.A. Antonioli, et al.
Prevalence of metaplasia at the gastroesophageal junction.
Lancet, 344 (1994), pp. 1533-1536
[41.]
D. Donahue, F. Navab.
Significance of short-segment Barrett's esophagus.
J Clin Gastroenterol, 25 (1997), pp. 480-484
[42.]
S. Nandurkar, N.J. Talley.
Barrett's esophagus: the long and the short of it.
Am J Gastroeterol, 94 (1999), pp. 30-40
[43.]
R. Mas, M. Krämer, E. Seifert, G. Rippin, M. Vieth, M. Stolte.
Short Barrett: prevalence and risk factors.
Scand J Gastroenterol, 34 (1999), pp. 1065-1070
[44.]
B.C. Morson, J.R. Belcher.
Adenocarcinoma of the esophagus and ectopic gastric mucosa.
Br J Cancer, 6 (1952), pp. 127-130
[45.]
P.R. Allison, A.S. Johnstone.
The oesophagus lined with gastric mucous membrane.
Thorax, 8 (1953), pp. 87-101
[46.]
A. Paull, J.S. Trier, M.D. Dalton, et al.
The histologic spectrum of Barrett's esophagus.
N Engl J Med, 295 (1976), pp. 476-480
[47.]
W.M. Weinstein, A.F. Ippoliti.
The diagnosis of Barrett's esophagus: goblets, goblets, goblets.
Gastrointest Endoscopy, 44 (1996), pp. 91-95
[48.]
S. Krishnamurthy, Y. Dayal.
Pancreatic metaplasia in Barrett's esophagus: an immunohistochemical study.
Am J Surg Pathol, 19 (1995), pp. 1172-1180
[49.]
S.J. Spechler, R.K. Goyal.
The columnar-lined esophagus, intestinal metaplasia and Norman Barrett.
Gastroenterology, 110 (1996), pp. 614-621
[50.]
R.E. Sampliner.
Practice guidelines on the diagnosis, surveillance and therapy of Barrett's esophagus.
Am J Gastroenterol, 93 (1998), pp. 1028-1032
[51.]
R.B. Ter, D.O. Castell.
Gastroesophageal reflux disease in patients with columnarlined esophagus.
Gastroenterol Clin North Am, 26 (1997), pp. 549-563
[52.]
K. Geboes.
Barrett's esophagus: the metaplasia-dysplasia-carcinoma sequence.
Acta Gastroenterol Belg, 63 (2000), pp. 13-17
[53.]
R.A.J. Ransford, J.A.Z. Jankowski.
Genetic versus environmental interactions in the oesophagitis –metaplasia–dysplasia-adenocarcinoma sequence of Barrett's esophagus.
Acta Gastroenterol Belg, 63 (2000), pp. 18-21
[54.]
R.N. Moersch, F.H. Ellis, J.R. McDonald.
Pathologic changes occurring in severe reflux esophagitis.
Surg Gynecol Obstet, 108 (1959), pp. 476-484
[55.]
M.C. Goldman, R.C. Boeckman.
Barrett's síndrome: case report with discussion about concepts of patogénesis.
Gastroenterology, 39 (1960), pp. 104-110
[56.]
S.N. Mossberg.
The columnar-lined esophagus –an acquired condition?.
Gastroenterology, 50 (1966), pp. 671-676
[57.]
J.N. Burgess, W.S. Payne, H.A. Andersen, et al.
Barrett's esophagus: the columnar epithelial-lined lower esophagus.
Mayo Clin Proc, 46 (1971), pp. 728-734
[58.]
J. Borrie, L. Golwater.
Columnar cell-lined esophagus: assessment of etiology and treatment. A 22 year experience.
J Thorac Cardiovasc Surg, 71 (1976), pp. 825-834
[59.]
C.G. Bremner, V.P. Lynch, F.H. Ellis.
Barrett's esophagus: congenital or acquired? An experimental study of esophageal mucosa regeneration in the dog.
Surgery, 68 (1970), pp. 209-216
[60.]
S.R. Hamilton, J.H. Yardley.
Regeneration of cardiac type mucosa and adquisition of Barrett's mucosa after oesophagogastrostomy.
Gastroenterology, 72 (1997), pp. 669-675
[61.]
D.A. Katzka, A.K. Rustgi.
Gastroesophageal reflux disease and Barrett's esophagus.
Med Clin North Am, 84 (2000), pp. 1137-1161
[62.]
M. Meyer, F. Vollmar, W. Barr.
Barrett's esophagus following total gastrectomy.
Endoscopy, 2 (1979), pp. 121-126
[63.]
A.K. Sandvik, T.B. Halvorsen.
Barrett's esophagus after total gastrectomy.
J Clin Gastroenterol, 10 (1998), pp. 587-588
[64.]
W.K. Kauer, J.H. Peters, T.R. De Meester, A.P. Ireland.
Mixed reflux of gastric and duodenal juices is more harmful to the esophagus than gastric juice alone.
Ann Surg, 222 (1995), pp. 525-531
[65.]
M.F. Vaezi, J.E. Richter.
GERD, DGER or both in Barrett's esophagus?.
Gastroenterology, 111 (1996), pp. 1192-1199
[66.]
P. Gillen, P. Keeling, P.J. Byrne, et al.
Experimental columnar metaplasia in the canine oesophagus.
Br J Surg, 75 (1988), pp. 113-115
[67.]
M. Pera, A. Cardesa, J.A. Bombi, et al.
The influence of esophagojejunostomy on the induction of adenocarcinoma of the distalesophagus in Sprague-Dawley rats by subcutaneous injection of 2,6-dimethylnitrosomorpholine.
Cancer Res, 49 (1989), pp. 6303-6308
[68.]
N. Myneni, A. Minocha.
Bile acids and esophageal injury: a resolution to the controversy?.
Am J Gastroenterol, 94 (1999), pp. 3649
[69.]
A. Trush, T.W. Kensler.
An overview of the relationship between oxidative stress and chemical carcinogenesis.
Free Radical Biol Med, 10 (1991), pp. 201-209
[70.]
M. Olyaee, P. Sontag, W. Salman, et al.
Mucosal reactive oxygen species production in oesophagitis and Barrett's esophagus.
Gut, 37 (1995), pp. 168-173
[71.]
Z. Abbas, A.S. Hussainy, F. Ibrahim, et al.
Barrett's esophagus and Helicobacter pylori.
J Gastroenterol Hepatol, 10 (1995), pp. 331-333
[72.]
R.D.J. Henihan, R.C. Stuart, N. Nolan, et al.
Barrett's esophagus and the presence of Helicobacter pylori.
Am J Gastroenterol, 93 (1998), pp. 542-546
[73.]
B.F.M. Werdmuller, R.J.L.F. Loffeld.
Helicobacter pylori infection has no role in the pathogenesis of reflux esophagitis.
Dig Dis Sci, 42 (1997), pp. 103-105
[74.]
Y. Romero, G.R. Locke.
Is there a GERD gene?.
Am J Gastroenterol, 94 (1999), pp. 1127-1128
[75.]
P. Chandasoma.
Pathophysiology of Barrett's esophagus.
Sem Thorac Cardiovasc Surg, 9 (1997), pp. 270-278
[76.]
S. Oberg, G.W.B. Clark, T.R. De Meester.
Barrett's esophagus. Update pathophysiology and management.
Hepatol Gastroenterol, 45 (1998), pp. 1348-1356
[77.]
E.J. Schweitzer, B.L. Bass, S. Batzari, J.W. Harmon, P.M. Young.
Lipid solubilization during bile salt induced esophageal mucosal barrier disrumption in the rabbit.
J Lab Clin Med, 110 (1987), pp. 172-179
[78.]
P. Gillen, P. Keeling, P.J. Byrne.
Barrett's esophagus: pH profile.
Br J Surg, 74 (1987), pp. 774-776
[79.]
J. Jankowski, B. Tregaskis, G. Coghill, A. Grant.
Epidermal growth factor in oesophagus.
Gut, 33 (1992), pp. 1448-1453
[80.]
J. Jankowski, N.A. Wright.
Gene expression in the alimentary tract: the modulation of epithelial proliferation, differentiation and peptide transcription by growth regulatory peptides.
Eur J Gastroenterol Hepatol, 11 (1992), pp. 78-85
[81.]
J. Jankowski.
Gene expression in Barrett's mucosa: acute and chronic adaptative responses in the oesophagus.
Gut, 34 (1993), pp. 1649-1650
[82.]
J.J. Thompson, K.R. Zeinsser, H.T. Enterline.
Barrett's metaplasia and adenocarcinoma of the esophagus and gastroesophageal junction.
Hum Pathol, 14 (1983), pp. 42-46
[83.]
J. Salo, E. Kivilaakso, I. Virtanen.
Barrett's esophagus originates from the squamous esophageal epithelium as judged from its cytokeratin profile.
Gastoenterology, 100 (1991), pp. 153A
[84.]
H.M. Shields, F. Zwas, D.A. Antonioli, et al.
Detection by scanning electron microscopy of a distinctive esophagel surface at the junction of squamous and Barrett's epithelium.
Dig Dis Sci, 38 (1993), pp. 93-108
[85.]
J.A. Boch, H.P. Shields, D.A. Antonioli, et al.
Distribution of cytoqueratin markers in Barrett's specialized columnar epithelium.
Gastroenterology, 112 (1997), pp. 760-765
[86.]
J. Hayward.
The lower end of the oesophagus.
Thorax, 16 (1961), pp. 36-41
[87.]
P.C. Nowel.
The clonal evolution of tumor cell populations.
Science, 194 (1976), pp. 23-28
[88.]
A.B. Stoler.
Genes and cancer.
Br Med Bull, 47 (1991), pp. 64-75
[89.]
J.A. Jankowski, N.A. Wright, S.J. Meltzer, G. Triadafilopoulos, K. Geboes, A.G. Casson.
et al Molecular evolution of the metaplasia-dysplasia-adenocarcinoma sequence in the esophagus.
Am J Pathol, 154 (1999), pp. 965-973
[90.]
N. Werner, J. Mueller, A. Walch, H. Höfler.
The molecular pathology of Barrett's esophagus.
Histol Histopathol, 14 (1999), pp. 553-559
[91.]
M.J. McKinley, D.R. Budman, D. Grueneberg, et al.
DNA content in Barrett's esophagus and esophageal malignancy.
Am J Gastroenterol, 82 (1987), pp. 1012-1020
[92.]
B.J. Reid, P.L. Blount, C.E. Rubin, D.S. Levine.
Flow-cytometric and histological progression to malignancy in Barrett's esophagus.
Gastroenterology, 102 (1992), pp. 1212-1219
[93.]
M.R. Gray, P.A. Hall, J. Nash, B. Ansari, D.P. Lana, A.N. Wingsnorth.
Epithelial proliferation in Barrett's esophagus by proliferating cell nuclear antigen immunolocalization.
Gastroenterology, 103 (1992), pp. 1769-1776
[94.]
B.J. Reid, C.A. Sánchez, P.L. Blount, D.S. Levine.
Barrett's esophagus: cell cycle abnormalities in advancing stages of neoplastic progression.
Gastroenterology, 105 (1993), pp. 119-209
[95.]
M.B. Fennerty, R.E. Sampliner.
Flow cytometry in Barrett's esophagus: when all is said and done, more is said than done!.
Am J Gastroenterol, 88 (1993), pp. 319-320
[96.]
K. Neshat, C.A. Sánchez, P.C. Galipeau, et al.
Barrett's esophagus: the biology of neoplastic progression.
Gastroenterolog Clin Biol, 18 (1994), pp. 71-76
[97.]
J. Jankowski, M. Werner, D. Hopwood, et al.
Abnormal expression of growth regulatory factors in Barrett's esophagus.
Clin Sci, 81 (1991), pp. 663-668
[98.]
J. Jankowski, G. Coghill, D. Hopwood, K.G. Wormsley.
Oncogenes and onco-suppressor gene in adenocarcinoma of the esophagus.
Gut, 33 (1992), pp. 1033-1038
[99.]
J. Mueller, M. Werner, J.R. Siewert.
Malignant progression in Barrett's esophagus: pathology and molecular biology.
Recent Results Cancer Res, 155 (2000), pp. 29-41
[100.]
R.H. Hardwick, N.A. Shepherd, P. Moorghen, et al.
C-erb-B2 overexpression in the dysplasia –carcinoma sequence of Barrett's oesophagus.
J Clin Pathol, 48 (1995), pp. 129-132
[101.]
O.M. Abdelatif, F.W. Chandler, L.R. Mills, et al.
Differential expression of c-myc and H-ras oncogenes in Barrett's epithelium.
Arch Pathol Lab Med, 115 (1991), pp. 880-885
[102.]
N. Arber, M. Lighdale, H. Rotterdam, et al.
Increased expression of the cyclin D1 gene in Barrett's esophagus.
Cancer Epidemiol Biomarkers Prev, 5 (1996), pp. 457-459
[103.]
N. Rioux-Leclercq, B. Turlin, F. Sutherland, N. Heresbach, B. Laundis, J.P. Campion.
et al Analysis of Ki-67, p53 and bcl-2 expression in the dysplasia-carcinoma sequence of Barrett's esophagus.
Oncology Reports, 6 (1999), pp. 877-882
[104.]
D. Coppola, R.H. Schreiber, L. Mora, W. Dalton, R.C. Warl.
Significance of Fas and retinoblastoma protein expression during the progression of Barrett's metaplasia to adenocarcinoma.
Ann Surg Oncology, 6 (1999), pp. 298-304
[105.]
T. Bailey, L. Biddleston, N. Shefherd, H. Barr.
Altered cadherin– catenin complexes in the dysplasia-adenocarcinoma sequence: correlation with disease progression and dedifferentiation.
Am J Pathol, 152 (1998), pp. 135-144
[106.]
E. Castella, A. Ariza, J. Fernández-Vasalo, C. López-Larrea.
Expression of CD44H and CD44v3 in normal esophagus, Barrett's mucosa and esophageal carcinoma.
J Clin Pathol, 49 (1996), pp. 489-492
[107.]
M.V. González, M.L. Artimez, L. Rodríguez, C. López-Larrea.
Mutation analysis of p53, APC and p16 genes in Barrett's esophagus, dysplasia and adenocarcinoma.
J Clin Pathol, 50 (1997), pp. 212-217
[108.]
C.C. Harris, M. Hollstein.
Clinical implications of the p53 tumor-suppresor gene.
N Engl J Med, 329 (1993), pp. 1318-1327
[109.]
D.S. Levine.
Barrett's esophagus and p53.
Lancet, 344 (1994), pp. 212-213
[110.]
B. Klump, C.J. Hsieh, K. Holzmann, F. Borchard, V. Gaco, A. Greschmidk, et al.
Diagnostic significance of nuclear p53 expression in the surveillance of Barrett's esophagus –a longitudinal study.
Z Gastroenterol, 37 (1999), pp. 1005-1011
[111.]
J.S. Hanas, M.R. Lerner, S.A. Lightfoot, C. Rackowscki, D.J. Wastens, D.V. Brackett, et al.
Expresión of the cyclin –dependant ki nase inhibitor p21 and p53 tumor supresor in dysplastic progression and adenocarcinoma in Barrett's esophagus.
Cancer, 86 (1999), pp. 756-763
[112.]
A.K. Kubba, N.A. Poole, A. Watson.
Role of p53 assessment in management of Barrett's esophagus.
Dig Dis Sci, 44 (1999), pp. 659-667
[113.]
S. Ramel, B.J. Reid, C.A. Sánchez, et al.
Evaluation of p53 protein expression in Barrett's esophagus by two-parameters flow cytometry.
Gastroenterology, 102 (1992), pp. 1220-1228
[114.]
M. Younes, L.M. Lebovits, L.V. Lechango, et al.
p53 protein accumulation in Barrett's metaplasia, dysplasia and carcinoma: a follow-up study.
Gastroenterology, 105 (1993), pp. 1637-1642
[115.]
P.L. Blount, J. Meltzer, J. Yin, Y. Huang, H.J. Wrasna, B.J. Reid.
Clonal ordering of p17 and 5q allelic losses in Barrett's dysplasia and adenocarcinoma.
Proc Natl Acad Sci, 90 (1993), pp. 3221-3225
[116.]
A. Giménez, L.M. Haro, P. Parrilla, J. Bermejo, M. Pérez-Guillermo, M.A. Ortiz.
Immunohistochemical detection of p53 protein could improve the management of some patients of Barrett's esophagus and mild histological alterations.
Arch Pathol Lab Med, 123 (1999), pp. 1260-1263
[117.]
B.N. Ames, L.S. Gold.
Too many rodent carcinogens: mitogenesis increases mutagenesis.
Science, 249 (1990), pp. 970-971
[118.]
P.L. Blount, S. Ramel, W.H. Raskind, et al.
17p allelic deletions and p53 protein overexpression in Barrett's adenocarcinoma.
Cancer Res, 52 (1991), pp. 5482-5486
[119.]
W.H. Raskind, T. Norwood, D.S. Levine, et al.
Persistent clonal areas and clonal expansion in Barrett's esophagus.
Cancer Res, 52 (1994), pp. 2946-2950
[120.]
J. Jankowski.
Clonality of esophageal carcinomas: genetic and epigenetics events leading to loss of genomic stability.
Dis Esophagus, 10 (1997), pp. 143-144
[121.]
F. Waridel, A. Estreicher, L. Bron, et al.
Field cancerisation and polyclonal p53 mutation in the upper aero-digestive tract.
Oncogenes, 14 (1997), pp. 163-169
[122.]
L.J. Prevo, C.A. Sánchez, P.C. Galipeau, J. Reid.
p-53 mutant clones and field effects in Barrett's esophagus.
Cancer Res, 59 (1999), pp. 4784-4787
[123.]
B.J. Reid, M.T. Barrett, P.C. Galipeau, et al.
Barrett's esophagus: ordering the events that lead to cancer.
Eur J Cancer Prev, 5 (1996), pp. 57-65
Copyright © 2002. Elsevier España, S.L.. Todos los derechos reservados
Descargar PDF
Opciones de artículo
es en pt

¿Es usted profesional sanitario apto para prescribir o dispensar medicamentos?

Are you a health professional able to prescribe or dispense drugs?

Você é um profissional de saúde habilitado a prescrever ou dispensar medicamentos