Información del artículo
Resumen
Es necesaria una inhibición muy potente del ácido gástrico para el tratamiento de la hemorragia digestiva por úlcera péptica. Un ensayo clínico controlado con placebo publicado recientemente ha demostrado claramente la eficacia del tratamiento con esomeprazol en perfusión para prevenir la recidiva hemorrágica en este contexto. Asimismo, la perfusión de un inhibidor de la bomba de protones antes de la endoscopia diagnóstica disminuye la necesidad de tratamiento endoscópico y acorta la estancia media de los pacientes.
Palabras clave:
Hemorragia digestiva por úlcera péptica
Inhibidor de la bomba de protones
Esomeprazol
Tratamiento endoscópico
Abstract
Gastric pH should be maintained at very high values to prevent peptic ulcer rebleeding. A recent randomized trial, however, has confirmed that intravenous infusion of esomeprazole decreases the rebleeding rate after endoscopic therapy. In addition, the use of proton pump inhibitor perfusion at admission before diagnostic endoscopy reduces the need for endoscopic therapy and shortens the mean length of hospital stay.
Keywords:
Peptic ulcer hemorrhage
Proton pump inhibitor
Esomeprazole
Endoscopic treatment
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