L. Fernández-Salazar¹¹, Á. Pérez-Aísa², D. Vaira³, G. Fiorini³, I.M. Saracino³, L. Jonaitis⁴, B. Tepes⁵, D. Bordin⁶, A. Keco-Huerga⁷, M. Castro-Fernández⁷, A. Lucendo⁸, L. Vologzhanina⁹, L. Bujanda¹⁰, N. Brglez Jurecic¹¹, M. Denkovski¹¹, Á. Lanas¹², S. Martínez-Domínguez¹², E. Alfaro¹², M. Leja¹³, R. Bumane¹³, E. Mammadov¹⁴, G. Babayeva¹⁴, U. Mahmudov¹⁵, M. Caldas¹⁶, L. Rodrigo¹⁷, F. Lerang¹⁸, G. Fadieienko¹⁹, R. Abdulkhakov²⁰, J.M. Huguet Malavés²¹, O. Zaytsev²², T. Ilchishina²³, N. Alcaide²⁴, B. Velayos²⁴, A. Silkanovna Sarsenbaeva²⁵, I. Bakulin²⁶, A.G. Gravina²⁷, M. Romano²⁷, M. Perona²⁸, S. Alekseenko²⁹, J. Barrio³⁰, M. Areia³¹, Ó. Núñez³², P. Bogomolov³³, B.J. Gómez Rodríguez³⁴, M. Domínguez-Cajal³⁵, J. Gómez Camarero³⁶, M. Jiménez Moreno³⁶, S. Georgopoulos³⁷, P. Almela Notari³⁸, A. Tonkic³⁹, R. Pellicano⁴⁰, H. Simsek⁴¹, L. Kunovský⁴², A. Gasbarrini⁴³, J.M. Botargues Bote⁴⁴, M. Fernández-Bermejo⁴⁵, P. Phull⁴⁶, M. Venerito⁴⁷, P. Malfertheiner⁴⁷, R. Rosania⁴⁷, A. Link⁴⁷, E. Iyo⁴⁸, J. Kupinskas⁴, O. Shvets⁴⁹, R. Marcos Pinto⁵⁰, T. Rokkas⁵¹, I. Simsek⁵², S. Smith⁵³, D. Boltin⁵⁴, D. Lamarque⁵⁵, D. Dobru⁵⁶, W. Marlicz⁵⁷, V. Milivojevic⁵⁸, L. Boyanova⁵⁹, V. Lamy⁶⁰, M. Doulberis⁶¹, P. Bytzer⁶², L. Capelle⁶³, O. Gridnyev⁶⁴, A. Ristimaki⁶⁵, A. Cano⁶⁶, I. Puig⁶⁶, O.P. Nyssen¹⁶, F. Mégraud⁶⁷, C. O'Morain⁵³ y J.P. Gisbert, en nombre de los investigadores Hp-EuReg<sup>16

1</sup>Hospital Clínico Universitario de Valladolid, Universidad de Valladolid. ²Agencia Sanitaria Costa del Sol, Red de Investigación en Servicios de Salud en Enfermedades Crónicas (REDISSEC), Marbella. ³Department of Surgical and Medical Sciences, University of Bologna, Bologna, Italia. ⁴Lithuanian University of Health Sciences, Kaunas, Lituania. ⁵5AM DC Rogaska, Rogaska Slatina, Eslovenia. ⁶A.S. Loginov Moscow Clinical Scientific Center, Moscow, Rusia. ⁷Hospital de Valme, Sevilla. ⁸Hospital General de Tomelloso. ⁹Gastrocentr, Perm, Rusia. ¹⁰Hospital Donostia/Instituto Biodonostia, Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas (CIBERehd), Universidad del País Vasco (UPV/EHU), San Sebastián. ¹¹Interni oddelek, Diagnostic Centre, Bled, Eslovenia. ¹²Hospital Clínico Universitario Lozano Blesa, Zaragoza. ¹³Digestive Diseases Centre GASTRO, Institute of Clinical and Preventive Medicine & Faculty of Medicine, University of Latvia, Riga, Letonia. ¹⁴Department of Therapy, Azerbaijan State Advanced Training Institute for Doctors named after A.ALIYEV, Baku, Azerbaiyán. ¹⁵Modern Hospital, Baku, Azerbaiyán. ¹⁶Hospital Universitario de La Princesa, Instituto de Investigación Sanitaria Princesa (IIS-IP), Universidad Autónoma de Madrid (UAM), y Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas (CIBERehd), Madrid. ¹⁷Hospital de Asturias, Oviedo. ¹⁸Østfold Hospital Trust, Grålum, Noruega. ¹⁹Digestive Ukrainian Academy of Medical Sciences, Kyiv, Ucrania. ²⁰Kazan State Medical University, Rusia. ²¹Hospital General Universitario de Valencia. ²²First Clinical Medical Centre, Kovrov, Rusia. ²³SM-clinic, Saint-Petersburg, Rusia. ²⁴Hospital Clínico Universitario, Valladolid. ²⁵Chelyabinsk Regional Clinical Hospital, Rusia. ²⁶North-western State Medical University St Petersburg, Rusia. ²⁷Università degli Studi della Campania "Luigi Vanvitelli", Napoli, Italia. ²⁸Hospital Quirón, Marbella. ²⁹Far Eastern State Medical University, Rusia. ³⁰Hospital Río Hortega, Valladolid. ³¹Portuguese Oncology Institute Coimbra, Portugal. ³²Hospital Universitario La Moraleja, Madrid. ³³Universal clinic-Private medical center, Moscow, Rusia. ³⁴Hospital Virgen Macarena, Sevilla. ³⁵Hospital San Jorge, Huesca. ³⁶Hospital Universitario de Burgos. ³⁷Athens Medical, P. Faliron General Hospital, Athens, Grecia. ³⁸Hospital General Universitario de Castellón. ³⁹University Hospital of Split, School of Medicine, University of Split, Croacia. ⁴⁰Outpatient clinic, Molinette-SGAS Hospital, University of Turin, Italia. ⁴¹Internal Medicine, Hacettepe, University School of Medicine, Ankara, Turquía. ⁴²Department of Gastroenterology and Internal Medicine and Department of Surgery, University Hospital Brno, Faculty of Medicine, Masaryk University, Brno, República Checa. ⁴³Medicina Interna, Fondazione Policlinico Universitario A. Gemelli IRCCS, Università Cattolica del Sacro Cuore, Roma, Italia. ⁴⁴Hospital Universitari de Bellvitge, L'Hospitalet de Llobregat. ⁴⁵Clínica San Francisco, Cáceres. ⁴⁶Aberdeen Royal Infirmary, Reino Unido. ⁴⁷Otto-von-Guericke University, Magdeburg, Alemania. ⁴⁸Hospital Comarcal de Inca, Mallorca. ⁴⁹Internal Medicine, National Medical University named after O.O.Bogomolets, Kyiv, Ucrania. ⁵⁰Centro Hospitalar do Porto Institute of Biomedical Sciences Abel Salazar, University of Porto, CINTESIS, University of Porto, Portugal. ⁵¹Henry Dunant Hospital, Athens, Grecia. ⁵²Dokuz Eylul University School of Medicine, Izmir, Turquía. ⁵³Trinity College Dublin, Dublin, Irlanda. ⁵⁴Rabin Medical Center, Beilinson Campus, Petah Tikva; Israel. ⁵⁵Hôpital Ambroise Paré,Université de Versailles St-Quentin en Yvelines, Boulogne Billancourt, Francia. ⁵⁶Targu Mures Emergency Hospital, Târgu Mure¿, Rumanía. ⁵⁷Pomeranian Medical University, Szczecin, Polonia. ⁵⁸Clinical Center of Serbia and School of Medicine, University of Belgrade, Belgrade, Serbia. ⁵⁹Medical Microbiology, Medical University of Sofia, Sofia, Bulgaria. ⁶⁰CHU de Charleroi, Charleroi, Bélgica. ⁶¹KSA Kantonsspital Aarau, Aarau, Suiza. ⁶²Clinical Medicine, Zealand University Hospital, Copenhagen University, Copenhagen, Dinamarca. ⁶³Meander Medical Center, Amersfoort, Países Bajos. ⁶⁴Government Institution 'L.T.Malaya Therapy National Institute of the National Academy of Medical Sciences of Ukraine', Kharkiv, Ucrania. ⁶⁵Department of Pathology, HUSLAB, HUS Diagnostic Center, Helsinki University Hospital; Medicum and Applied Tumor Genomics, Research Programs Unit, Faculty of Medicine, University of Helsinki, Helsinki, Finlandia. ⁶⁶Althaia Xarxa Assistencial Universitària de Manresa and Universitat de Vic-Universitat Central de Catalunya (UVicUCC), Manresa, SPAIN. ⁶⁷INSERM 1053, Université de Bordeaux, Bordeaux, Francia.