Estadísticas

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      "titulo" => "Últimos avances en pancreatitis aguda"
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          "autoresLista" => "J. Enrique Domínguez Muñoz"
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        "autoresLista" => "José Lariño Noia"
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        "titulo" => "Resumen"
        "resumen" => "<span id="abst0005" class="elsevierStyleSection elsevierViewall"><p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">El c&#225;ncer de p&#225;ncreas contin&#250;a siendo una entidad de p&#233;simo pron&#243;stico&#46; Apenas existen avances terap&#233;uticos en los &#250;ltimos a&#241;os&#44; por lo que la mayor parte del esfuerzo se centra en tratar de diagnosticar la enfermedad en un estadio precoz&#46; En este sentido&#44; la ultrasonograf&#237;a endosc&#243;pica y diferentes herramientas asociadas a esta&#44; como la elastograf&#237;a o el uso de contrastes intravenosos&#44; contin&#250;an siendo la piedra angular en el diagn&#243;stico diferencial&#46; Los tumores qu&#237;sticos del p&#225;ncreas&#44; en especial el tumor papilar mucinoso intraductal&#44; con su conocido potencial de malignidad&#44; inundan de trabajos esta &#250;ltima edici&#243;n de la Digestive Disease Week&#46; Adem&#225;s de incidir en los problemas para su caracterizaci&#243;n preoperatoria&#44; tanto por la evaluaci&#243;n citol&#243;gica por ultrasonograf&#237;a endosc&#243;pica&#44; incluso con la presencia de pat&#243;logo &#8220;en la sala&#8221;&#44; como por el estudio de marcadores intraqu&#237;sticos&#44; se potencia el papel de otras t&#233;cnicas como la endomicroscopia l&#225;ser confocal o el uso de contrastes intravenosos para la caracterizaci&#243;n del n&#243;dulo mural&#46; Abundan los trabajos acerca de la historia natural del tumor papilar mucinoso intraductal&#44; que en mayor medida validan el esp&#237;ritu&#44; cada vez m&#225;s conservador&#44; de las recientes gu&#237;as internacionales de Fukuoka&#46; Ciertos aspectos&#44; como las comorbilidades&#44; a la hora de considerar la cirug&#237;a o el ritmo de crecimiento de la neoplasia se ponen de relieve&#46; En el campo del tratamiento comienza a tomar relevancia&#44; en casos concretos&#44; la inyecci&#243;n mediante ultrasonograf&#237;a endosc&#243;pica de gemcitabina y paclitaxel sin necesidad de alcohol como tratamiento ablativo de las neoplasias qu&#237;sticas mucinosas</p></span>"
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        "resumen" => "<span id="abst0010" class="elsevierStyleSection elsevierViewall"><p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">Pancreatic cancer continues to have an extremely poor prognosis&#46; There have been hardly any therapeutic advances in the last few years and consequently attention is focussed on early diagnosis&#46; In this regard&#44; endoscopic ultrasonography and several associated techniques&#44; such as electrography or the use of intravenous contrast agents&#44; continue to be the cornerstone of differential diagnosis&#46; In the latest Digestive Diseases Week&#44; numerous presentations were made on cystic pancreatic tumours&#44; especially intraductal papillary mucinous tumours&#44; with their well-known potential for malignant transformation&#46; In addition to the problems of the preoperative characterization of these entities&#44; by both endoscopic ultrasound cytological evaluation-even with the presence of an on-site pathologist &#8211;and by intracystic markers&#44; the role of other techniques was also mentioned&#44; such as confocal laser endomicroscopy or the use of intravenous contrast agents to characterize the wall nodule&#46; There were numerous studies on the natural history of intraductal papillary mucinous tumours&#44; which mainly supported the increasingly conservative approach adopted by the recent Fukuoka international guidelines&#46; Certain aspects were highlighted&#44; such as comorbidities&#44; when considering surgery&#44; or the growth rate of the tumour&#46; In treatment&#44; endoscopic ultrasound-guided injection of gemcitabine and paclitaxel&#44; without the need for alcohol as an ablative treatment of mucinous cystic tumours&#44; is gaining ground in specific cases&#46;</p></span>"
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