Brote hospitalario de Achromobacter denitrificans relacionado con el uso de clorhexidina contaminada

Información del artículo

Resumen

El objetivo de este artículo es describir una serie de casos de pacientes con pseudobacteriemia causada por Achromobacter denitrificans, germen aislado a partir de los hemocultivos de 14 pacientes hospitalizados en una institución de alta complejidad de Medellín. Los casos estuvieron asociados con el uso de clorhexidina al 4% en jabón contaminado. Todos los pacientes recibieron antibióticos con resultados favorables, posiblemente debido a la baja virulencia de este microorganismo y a las medidas oportunas adoptadas por el Grupo de Control de Infecciones del hospital.

Palabras clave:

Achromobacter denitrificans

bacteriemia

brote

clorhexidina

Abstract

The aim of this paper is to describe a case series of pseudobacteremia caused by Achromobacter denitrificans, isolated from blood cultures from 14 hospitalized patients in a tertiary care institution in Medellín. The cases were associated with the use of contaminated 4% chlorhexidine soap. All patients received antibiotic treatment and had favorable results, possibly because of the low virulence of this organism and the timely measures taken by the hospital infections control group.

Key words:

Achromobacter denitrificans

bacteremia

outbreak

chlorhexidine

El Texto completo está disponible en PDF

Referencias

[1.]

P. Schreckenberger, M. Daneshvar, D. Hollis.

Acinetobacter, Achromobacter, Chryseobacterium Moraxella, and other nonfermentative Gram-negative rods.

Manual of clinical microbiology., Ninth edition, pp. 770-802

[2.]

V. Eshwara, C. Mukhopadhyay, S. Mohan, R. Prakash, G. Pai.

Two unique presentations of Achromobacter xylosoxidans infections in clinical settings.

J Infect Dev Ctries, 5 (2011), pp. 134-141

[3.]

P. Pronovost, D. Needham, S. Berenholtz, D. Sinopoli, H. Chu, S. Cosgrove, et al.

An intervention to decrease catheter-related bloodstream infections in the ICU.

N Engl J Med, 355 (2006), pp. 2725-2732

http://dx.doi.org/10.1056/NEJMoa061115 | Medline

[4.]

D. Paulson.

Comparative evaluation of five surgical hand scrub preparations.

AORNJ Journal, 60 (1994), pp. 246-256

[5.]

E. Larson.

APIC guideline for handwashing and hand antisepsis in health care settings.

Am J Infect Control, 23 (1995), pp. 251-269

Medline

[6.]

J.P. Steinberg, E.M. Burd.

Other Gram-negative and Gram-variable bacilli.

Principles and practice of infectious diseases, Seventh edition, pp. 3015-3033

[7.]

J. Vu-Thien, D. Darbord, C. Moissenet, J. Dulot, P. Dufourcq, A. Marsol, et al.

Investigation of an outbreak of wound infections due to Alcaligenes xylosoxidans transmitted by chlorhexidine in a burns unit.

Eur J Clin Microbiol Infect Dis, 17 (1998), pp. 724-726

Medline

[8.]

K. Olshtain-Pops, C. Block, V. Temper, C. Hidalgo-Grass, I. Gross, A.E. Moses, et al.

An outbreak of Achromobacter xylosoxidans associated with ultrasound gel used during transrectal ultrasound guided prostate biopsy.

J Urol, 185 (2011), pp. 144-147

http://dx.doi.org/10.1016/j.juro.2010.08.093 | Medline

[9.]

E. Siebor, C. Llanes, I. Lafon, A. Ogier-Desserrey, J.M. Duez, A. Pechinot, et al.

Presumed pseudobacteremia outbreak resulting from contamination of proportional disinfectant dispenser.

Eur J Clin Microbiol Infect Dis, 26 (2006), pp. 195-198

http://dx.doi.org/10.1007/s10096-007-0260-1 | Medline

[10.]

K. McGann, M. Provencher, C. Hoegg, G. Talbot.

Achromobacter xylosoxidans bacteremia.

Infect Control Hosp Epidemiol, 11 (1990), pp. 539-541

Medline

[11.]

M. Ahmed, C. Nistal, R. Jayan, M. Kuduvalli, H. Anijeet.

Achromobacter xylosoxidans, an emerging pathogen in catheter-related infection in dialysis population causing prosthetic valve endocarditis: A case report and review of literature.

Clin Nephrol, 71 (2009), pp. 350-354

Medline

Indexada en:

Síguenos:

Indexada en:

Síguenos:

Suscríbase a la newsletter