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"documento" => "simple-article" "crossmark" => 1 "subdocumento" => "cor" "cita" => "Med Clin. 2023;160:278" "abierto" => array:3 [ "ES" => false "ES2" => false "LATM" => false ] "gratuito" => false "lecturas" => array:1 [ "total" => 0 ] "en" => array:10 [ "idiomaDefecto" => true "cabecera" => "<span class="elsevierStyleTextfn">Letter to the Editor</span>" "titulo" => "Reply" "tienePdf" => "en" "tieneTextoCompleto" => "en" "paginas" => array:1 [ 0 => array:1 [ "paginaInicial" => "278" ] ] "titulosAlternativos" => array:1 [ "es" => array:1 [ "titulo" => "Respuesta" ] ] "contieneTextoCompleto" => array:1 [ "en" => true ] "contienePdf" => array:1 [ "en" => true ] "autores" => array:1 [ 0 => array:2 [ "autoresLista" => "Pilar Brito-Zerón, Roberto Pérez-Álvarez, Manuel Ramos-Casals" "autores" => array:3 [ 0 => array:2 [ "nombre" => "Pilar" "apellidos" => "Brito-Zerón" ] 1 => array:2 [ "nombre" => "Roberto" "apellidos" => "Pérez-Álvarez" ] 2 => array:2 [ "nombre" => "Manuel" "apellidos" => "Ramos-Casals" ] ] ] ] ] "idiomaDefecto" => "en" "Traduccion" => array:1 [ "es" => array:9 [ "pii" => "S0025775322006728" "doi" => "10.1016/j.medcli.2022.11.017" "estado" => "S300" "subdocumento" => "" "abierto" => array:3 [ "ES" => false "ES2" => false "LATM" => false ] "gratuito" => false "lecturas" => array:1 [ "total" => 0 ] "idiomaDefecto" => "es" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0025775322006728?idApp=UINPBA00004N" ] ] "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S2387020623000967?idApp=UINPBA00004N" "url" => "/23870206/0000016000000006/v1_202303262137/S2387020623000967/v1_202303262137/en/main.assets" ] ] "en" => array:13 [ "idiomaDefecto" => true "cabecera" => "<span class="elsevierStyleTextfn">Letter to the Editor</span>" "titulo" => "Sarcoidosis and lymphoma" "tieneTextoCompleto" => true "saludo" => "Dear Editor," "paginas" => array:1 [ 0 => array:1 [ "paginaInicial" => "277" ] ] "autores" => array:1 [ 0 => array:4 [ "autoresLista" => "Jose Luis Callejas Rubio, Noberto Ortego Centeno" "autores" => array:2 [ 0 => array:4 [ "nombre" => "Jose Luis" "apellidos" => "Callejas Rubio" "email" => array:1 [ 0 => "jlcalleja@telefonica.net" ] "referencia" => array:2 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "aff0005" ] 1 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">*</span>" "identificador" => "cor0005" ] ] ] 1 => array:3 [ "nombre" => "Noberto" "apellidos" => "Ortego Centeno" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">b</span>" "identificador" => "aff0010" ] ] ] ] "afiliaciones" => array:2 [ 0 => array:3 [ "entidad" => "Unidad de Enfermedades Sistémicas, Servicio de Medicina Interna, Hospital Clínico Universitario San Cecilio, IBS Granada, Granada, Spain" "etiqueta" => "a" "identificador" => "aff0005" ] 1 => array:3 [ "entidad" => "Cátedra de Medicina, Departamento de Medicina, Universidad de Granada, IBS Granada, Granada, Spain" "etiqueta" => "b" "identificador" => "aff0010" ] ] "correspondencia" => array:1 [ 0 => array:3 [ "identificador" => "cor0005" "etiqueta" => "⁎" "correspondencia" => "Corresponding author." ] ] ] ] "titulosAlternativos" => array:1 [ "es" => array:1 [ "titulo" => "Sarcoidosis y linfoma" ] ] "textoCompleto" => "<span class="elsevierStyleSections"><p id="par0005" class="elsevierStylePara elsevierViewall">We have read with interest the excellent review on sarcoidosis recently published in your journal by Brito-Zerón et al.<a class="elsevierStyleCrossRef" href="#bib0005"><span class="elsevierStyleSup">1</span></a> We would like to make a few comments on an aspect that concerns us as physicians who monitor patients with this pathology, namely the so-called sarcoidosis–lymphoma syndrome, which is not described in the review.</p><p id="par0010" class="elsevierStylePara elsevierViewall">In the section on lymph node sarcoidosis, the authors refer to the differential diagnosis with other diseases such as tuberculosis, metastasis and, above all, lymphoma, pointing to the lymph node diameter, over or under 3 cm, as indicative of the latter possibility. In the section on imaging tests, they highlight the role of positron emission tomography (PET–CT) in cases in which a systemic evaluation of the disease is necessary.</p><p id="par0015" class="elsevierStylePara elsevierViewall">The association of sarcoidosis and lymphoma is known and was named sarcoidosis–lymphoma syndrome by Brincker.<a class="elsevierStyleCrossRef" href="#bib0010"><span class="elsevierStyleSup">2</span></a> Patients with sarcoidosis have up to an 11-fold increased risk of developing lymphoma, usually Hodgkin’s lymphoma, which can occur simultaneously or within years of disease diagnosis, which is an even more challenging issue.<a class="elsevierStyleCrossRef" href="#bib0015"><span class="elsevierStyleSup">3</span></a> In the absence of clinical markers, PET–CT could probably be the best tool in the follow-up of patients in whom this complication is suspected.<a class="elsevierStyleCrossRefs" href="#bib0020"><span class="elsevierStyleSup">4,5</span></a></p><p id="par0020" class="elsevierStylePara elsevierViewall">There are several questions that we will have to address:<ul class="elsevierStyleList" id="lis0005"><li class="elsevierStyleListItem" id="lsti0005"><span class="elsevierStyleLabel">–</span><p id="par0025" class="elsevierStylePara elsevierViewall">Which patients are most at risk for sarcoidosis–lymphoma syndrome?</p></li><li class="elsevierStyleListItem" id="lsti0010"><span class="elsevierStyleLabel">–</span><p id="par0030" class="elsevierStylePara elsevierViewall">Is the degree of activity in the PET–CT a risk factor for its development?</p></li><li class="elsevierStyleListItem" id="lsti0015"><span class="elsevierStyleLabel">–</span><p id="par0035" class="elsevierStylePara elsevierViewall">In this case, even if the lymphadenopathies are asymptomatic, can their treatment prevent or delay progression to lymphoma?</p></li></ul></p><p id="par0040" class="elsevierStylePara elsevierViewall">Until answers are available, it is important never to forget this association and, in cases of suspected diagnosis, probably consider follow-up PET–CT scans and, of course, include biopsies of the most active lymph nodes.</p><span id="sec0005" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0005">Conflict of interests</span><p id="par0045" class="elsevierStylePara elsevierViewall">None.</p></span></span>" "textoCompletoSecciones" => array:1 [ "secciones" => array:2 [ 0 => array:2 [ "identificador" => "sec0005" "titulo" => "Conflict of interests" ] 1 => array:1 [ "titulo" => "References" ] ] ] "pdfFichero" => "main.pdf" "tienePdf" => true "bibliografia" => array:2 [ "titulo" => "References" "seccion" => array:1 [ 0 => array:2 [ "identificador" => "bibs0005" "bibliografiaReferencia" => array:5 [ 0 => array:3 [ "identificador" => "bib0005" "etiqueta" => "1" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Sarcoidosis" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:3 [ 0 => "P. Brito-Zerón" 1 => "R. Pérez-Álvarez" 2 => "M. Ramos-Casals" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1016/j.medcli.2022.03.009" "Revista" => array:6 [ "tituloSerie" => "Med Clin (Barc)" "fecha" => "2022" "volumen" => "159" "paginaInicial" => "195" "paginaFinal" => "204" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/35680449" "web" => "Medline" ] ] ] ] ] ] ] ] 1 => array:3 [ "identificador" => "bib0010" "etiqueta" => "2" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "The sarcoidosis-lymphoma syndrome" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:1 [ 0 => "H. Brincker" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1038/bjc.1986.199" "Revista" => array:6 [ "tituloSerie" => "Br J Cancer" "fecha" => "1986" "volumen" => "54" "paginaInicial" => "467" "paginaFinal" => "473" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/3756082" "web" => "Medline" ] ] ] ] ] ] ] ] 2 => array:3 [ "identificador" => "bib0015" "etiqueta" => "3" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Clinical differences in sarcoidosis patients with and without lymphoma: a single-centre retrospective cohort analysis" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:6 [ 0 => "S. Cerri" 1 => "M. Fontana" 2 => "S. Balduzzi" 3 => "L. Potenza" 4 => "P. Faverio" 5 => "M. Luppi" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1183/13993003.02470-2018" "Revista" => array:5 [ "tituloSerie" => "Eur Respir J" "fecha" => "2019" "volumen" => "54" "paginaInicial" => "1802470" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/31346006" "web" => "Medline" ] ] ] ] ] ] ] ] 3 => array:3 [ "identificador" => "bib0020" "etiqueta" => "4" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "The role of PET in the management of sarcoidosis" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:3 [ 0 => "R.J. Vender" 1 => "H. Aldahham" 2 => "R. Gupta" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1097/MCP.0000000000000892" "Revista" => array:6 [ "tituloSerie" => "Curr Opin Pulm Med" "fecha" => "2022" "volumen" => "28" "paginaInicial" => "485" "paginaFinal" => "491" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/35869739" "web" => "Medline" ] ] ] ] ] ] ] ] 4 => array:3 [ "identificador" => "bib0025" "etiqueta" => "5" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "In which patients with sarcoidosis is FDG PET/CT Indicated?" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:2 [ 0 => "R.G.M. Keijsers" 1 => "J.C. 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Journal Information
Vol. 160. Issue 6.
Pages 277 (March 2023)
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Vol. 160. Issue 6.
Pages 277 (March 2023)
Letter to the Editor
Sarcoidosis and lymphoma
Sarcoidosis y linfoma
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Med Clin. 2023;160:27810.1016/j.medcle.2022.11.008
Pilar Brito-Zerón, Roberto Pérez-Álvarez, Manuel Ramos-Casals
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