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array:23 [ "pii" => "S0025775300715636" "issn" => "00257753" "doi" => "10.1016/S0025-7753(00)71563-6" "estado" => "S300" "fechaPublicacion" => "2000-01-01" "aid" => "71563" "copyright" => "Elsevier España, S.L.. Todos los derechos reservados" "copyrightAnyo" => "2000" "documento" => "article" "crossmark" => 0 "subdocumento" => "fla" "cita" => "Med Clin. 2000;115:370-4" "abierto" => array:3 [ "ES" => false "ES2" => false "LATM" => false ] "gratuito" => false "lecturas" => array:2 [ "total" => 1363 "formatos" => array:3 [ "EPUB" => 6 "HTML" => 1270 "PDF" => 87 ] ] "itemSiguiente" => array:18 [ "pii" => "S0025775300715648" "issn" => "00257753" "doi" => "10.1016/S0025-7753(00)71564-8" "estado" => "S300" "fechaPublicacion" => "2000-01-01" "aid" => "71564" "copyright" => "Elsevier España, S.L." "documento" => "article" "crossmark" => 0 "subdocumento" => "fla" "cita" => "Med Clin. 2000;115:375-6" "abierto" => array:3 [ "ES" => false "ES2" => false "LATM" => false ] "gratuito" => false "lecturas" => array:2 [ "total" => 2259 "formatos" => array:3 [ "EPUB" => 6 "HTML" => 2121 "PDF" => 132 ] ] "es" => array:10 [ "idiomaDefecto" => true "titulo" => "Seroprevalencia de la toxoplasmosis en mujeres en edad fértil (1992-1999)" "tienePdf" => "es" "tieneTextoCompleto" => 0 "tieneResumen" => array:2 [ 0 => "es" 1 => "en" ] "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "375" "paginaFinal" => "376" ] ] "titulosAlternativos" => array:1 [ "en" => array:1 [ "titulo" => "Seroprevalence of toxoplasmosis in women of childbearing age (1992-1999)." ] ] "contieneResumen" => array:2 [ "es" => true "en" => true ] "contienePdf" => array:1 [ "es" => true ] "autores" => array:2 [ 0 => array:2 [ "autoresLista" => "Marc Pujol-Riqué, Cristina Danés, M. Eugenia Valls, M. Teresa Jiménez de Anta" "autores" => array:4 [ 0 => array:2 [ "nombre" => "Marc" "apellidos" => "Pujol-Riqué" ] 1 => array:2 [ "nombre" => "Cristina" "apellidos" => "Danés" ] 2 => array:2 [ "nombre" => "M." "apellidos" => "Eugenia Valls" ] 3 => array:2 [ "nombre" => "M." "apellidos" => "Teresa Jiménez de Anta" ] ] ] 1 => array:2 [ "autoresLista" => "Llorenç Quintó, Oriol Coll" "autores" => array:2 [ 0 => array:2 [ "nombre" => "Llorenç" "apellidos" => "Quintó" ] 1 => array:2 [ "nombre" => "Oriol" "apellidos" => "Coll" ] ] ] ] ] "idiomaDefecto" => "es" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0025775300715648?idApp=UINPBA00004N" "url" => "/00257753/0000011500000010/v1_201307291743/S0025775300715648/v1_201307291743/es/main.assets" ] "itemAnterior" => array:18 [ "pii" => "S0025775300715624" "issn" => "00257753" "doi" => "10.1016/S0025-7753(00)71562-4" "estado" => "S300" "fechaPublicacion" => "2000-01-01" "aid" => "71562" "copyright" => "Elsevier España, S.L." "documento" => "article" "crossmark" => 0 "subdocumento" => "fla" "cita" => "Med Clin. 2000;115:366-9" "abierto" => array:3 [ "ES" => false "ES2" => false "LATM" => false ] "gratuito" => false "lecturas" => array:2 [ "total" => 4412 "formatos" => array:3 [ "EPUB" => 6 "HTML" => 3773 "PDF" => 633 ] ] "es" => array:10 [ "idiomaDefecto" => true "titulo" => "Utilidad de la mielografía mediante resonancia magnética en el diagnóstico de las enfermedades de la columna vertebral" "tienePdf" => "es" "tieneTextoCompleto" => 0 "tieneResumen" => array:2 [ 0 => "es" 1 => "en" ] "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "366" "paginaFinal" => "369" ] ] "titulosAlternativos" => array:1 [ "en" => array:1 [ "titulo" => "Value of MR myelography In the diagnosis of the spine disorders" ] ] "contieneResumen" => array:2 [ "es" => true "en" => true ] "contienePdf" => array:1 [ "es" => true ] "autores" => array:1 [ 0 => array:2 [ "autoresLista" => "Pilar Ferrer, Luis Martí-Bonmatí, Enrique Mollá, Carlos Casillas" "autores" => array:4 [ 0 => array:2 [ "nombre" => "Pilar" "apellidos" => "Ferrer" ] 1 => array:2 [ "nombre" => "Luis" "apellidos" => "Martí-Bonmatí" ] 2 => array:2 [ "nombre" => "Enrique" "apellidos" => "Mollá" ] 3 => array:2 [ "nombre" => "Carlos" "apellidos" => "Casillas" ] ] ] ] ] "idiomaDefecto" => "es" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0025775300715624?idApp=UINPBA00004N" "url" => "/00257753/0000011500000010/v1_201307291743/S0025775300715624/v1_201307291743/es/main.assets" ] "es" => array:15 [ "idiomaDefecto" => true "titulo" => "Agregación entre hermanos de factores de riesgo cardiovascular: estudio de Cuenca" "tieneTextoCompleto" => 0 "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "370" "paginaFinal" => "374" ] ] "autores" => array:2 [ 0 => array:4 [ "autoresLista" => "Vicente Martínez Vizcaíno, Ricardo Franquelo Gutiérrez" "autores" => array:2 [ 0 => array:4 [ "nombre" => "Vicente" "apellidos" => "Martínez Vizcaíno" "email" => array:1 [ 0 => "vmvizcai@enf-cu.uclm.es" ] "referencia" => array:2 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "aff0005" ] 1 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">*</span>" "identificador" => "cor0005" ] ] ] 1 => array:3 [ "nombre" => "Ricardo" "apellidos" => "Franquelo Gutiérrez" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">b</span>" "identificador" => "aff0010" ] ] ] ] "afiliaciones" => array:2 [ 0 => array:3 [ "entidad" => "Área de Salud Pública. EU de Enfermería. Universidad de Castilla-La Mancha. Cuenca." "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "aff0005" ] 1 => array:3 [ "entidad" => "Laboratorio Hospital Virgen de la Luz. Cuenca." "etiqueta" => "<span class="elsevierStyleSup">b</span>" "identificador" => "aff0010" ] ] "correspondencia" => array:1 [ 0 => array:3 [ "identificador" => "cor0005" "etiqueta" => "*" "correspondencia" => "Correspondencia: Dr. V. Martínez Vizcaíno. Universidad de Castilla-La Mancha. EU de Enfermería. Área de Salud Pública. Edificio Melchor Cano. Camino de Pozuelo, s/n. 16071 Cuenca." ] ] ] 1 => array:3 [ "autoresLista" => "Ana Lozano Muńoz, Fernando Salcedo Aguilar, Alberto Morant Sánchez, Amparo Contreras Herráiz" "autores" => array:4 [ 0 => array:2 [ "nombre" => "Ana" "apellidos" => "Lozano Muńoz" ] 1 => array:2 [ "nombre" => "Fernando" "apellidos" => "Salcedo Aguilar" ] 2 => array:2 [ "nombre" => "Alberto" "apellidos" => "Morant Sánchez" ] 3 => array:2 [ "nombre" => "Amparo" "apellidos" => "Contreras Herráiz" ] ] "afiliaciones" => array:1 [ 0 => array:1 [ "entidad" => "Centro de Salud Cuenca I. Unidad Docente de Medicina de Familia y Comunitaria. Cuenca.Cuenca" ] ] ] ] "titulosAlternativos" => array:1 [ "en" => array:1 [ "titulo" => "Sib-sib correlations of cardiovascular risk factors: the Cuenca study (Spain)" ] ] "pdfFichero" => "main.pdf" "tienePdf" => true "fechaRecibido" => "2000-03-13" "fechaAceptado" => "2000-07-25" "PalabrasClave" => array:1 [ "es" => array:1 [ 0 => array:4 [ "clase" => "keyword" "titulo" => "Palabras clave" "identificador" => "xpalclavsec223081" "palabras" => array:5 [ 0 => "Colesterol" 1 => "Lipoproteínas" 2 => "Escolares" 3 => "Apolipoproteínas" 4 => "Agregación familiar" ] ] ] ] "tieneResumen" => true "resumen" => array:2 [ "es" => array:1 [ "resumen" => "<span class="elsevierStyleSectionTitle">Fundamento</span><p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">Estimar la agregación entre hermanos de los factores de riesgo cardiovascular.</p> <span class="elsevierStyleSectionTitle">Sujetos y método</span><p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">Segundo estudio transversal incluido en un seguimiento de factores de riesgo cardiovascular en escolares. Se incluyeron 115 parejas de hermanos seleccionadas entre los escolares de la cohorte del estudio de Cuenca y sus hermanos en edad escolar. Se determinaron variables sociodemogrÁficas, peso, talla, índice de masa corporal, presión arterial sistólica y diastólica, concentración plasmÁtica en ayunas de colesterol total, cLDL, cHDL, triglicéridos, apolipoproteínas A-I y B 100 y lipoproteína (a).</p> <span class="elsevierStyleSectionTitle">Resultados</span><p id="spar0015" class="elsevierStyleSimplePara elsevierViewall">Los coeficientes de correlación parcial entre hermanos de las concentraciones plasmáticas de lípidos y lipoproteínas, ajustados por edad e índice de masa corporal, presentan valores positivos bastante elevados en general, con valores entre 0,27 para los triglicéridos y 0,48 para el cHDL, resultando estadísticamente significativos (p 0,005) todos ellos. Así mismo, el coeficiente de correlación intraclase ofrece valores moderadamente elevados (entre 0,20 y 0,48). Ambos coeficientes eran mucho más elevados en las parejas hermano-hermano que en las parejas hermana-hermana. El índice de Quetelet presentaba valores de los coeficientes ligeramente más bajos y sin diferencias relevantes entre los distintos tipos de parejas. Los coefi-cientes entre valores de presión arterial fueron bajos (p > 0,05).</p> <span class="elsevierStyleSectionTitle">Conclusiones</span><p id="spar0020" class="elsevierStyleSimplePara elsevierViewall">Se evidencia una notable asociación entre las concentraciones plasmáticas de lípidos entre hermanos, observándose diferencias según el sexo de las parejas, lo que lleva a pensar en una herencia genética ligada al sexo de estos valores lipídicos. También se aprecia una asociación, aunque más débil, de los valores del índice de masa corporal. Por último, la agregación entre hermanos de los valores de presión arterial en nuestro estudio se muestra bastante débil.</p>" ] "en" => array:1 [ "resumen" => "<span class="elsevierStyleSectionTitle">Background</span><p id="spar0025" class="elsevierStyleSimplePara elsevierViewall">To analyze the sib-sib correlation of the cardiovascular risk factors.</p> <span class="elsevierStyleSectionTitle">Subjects and method</span><p id="spar0030" class="elsevierStyleSimplePara elsevierViewall">A cross-sectional study was made in 115 sibling pairs. Sociodemographic variables, weight, height, body mass index, systolic blood pressure, diastolic blood pressure and fasting plasma total cholesterol, LDL-C, HDL-C, apo A-I, apo B 100 and Lp(a) concentra-tions.</p> <span class="elsevierStyleSectionTitle">Results</span><p id="spar0035" class="elsevierStyleSimplePara elsevierViewall">Partial correlation coefficients adjusted for age and body mass index for plasmatic lipid and lipoprotein levels in sibling pairs showed positive values range from 0.27 for triglyceri-de to 0.53 for apo B/apo A-I ratio (p 0.005). Likewise, the intraclass correlation coefficients ranged from 0.20 to 0.48. Both coefficient were higher in brother-brother pairs than in sister-sister pairs. The Quetelet index coefficients were slightly lower than lipid coefficients, and showed similar values among the different kinds of sibling pairs. Blood pressure coefficients were low (p > 0.05).</p> <span class="elsevierStyleSectionTitle">Conclusions</span><p id="spar0040" class="elsevierStyleSimplePara elsevierViewall">An association for lipid and lipoprotein plasma concentrations has been evidenced in sibling pairs. This association is stronger in brother-brother pairs than in sister-sister pairs. This fact could indicate a sex linked heredability of lipid and lipoprotein levels. A weaker association for boby mass index has been observed. Sib-sib aggregation of blood pressure levels is not significant.</p>" ] ] "NotaPie" => array:1 [ 0 => array:1 [ "nota" => "<p class="elsevierStyleNotepara">Trabajo financiado mediante beca de la Consejería de Sanidad de la Junta de Comunidades de Castilla-La Mancha</p>" ] ] "bibliografia" => array:2 [ "titulo" => "Referencias BibliogrÁFicas" "seccion" => array:1 [ 0 => array:2 [ "identificador" => "bibs0005" "bibliografiaReferencia" => array:40 [ 0 => array:3 [ "identificador" => "bib0005" "etiqueta" => "1." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Atherosclerosis of the aorta and coronary arteries and cardiovascular risk factors in persons aged 6 to 30 years and studied at necropsy (The Bogalusa Heart Study)" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:6 [ 0 => "G.S. Berenson" 1 => "W.A. Wattigney" 2 => "R.E. Tracy" 3 => "W.P. Newman III" 4 => "S.R. Srinivasan" 5 => "L.S. 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