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Consultó por coxalgia progresiva de 2 años de evolución. En Rx de cadera (<a class="elsevierStyleCrossRef" href="#fig0005">fig. 1</a>) se evidenció la desaparición de la cabeza femoral, que en radiografías previas (<a class="elsevierStyleCrossRef" href="#fig0010">fig. 2</a>) se mostraba sin alteraciones. Completado el estudio radiológico con RMN y TAC (<a class="elsevierStyleCrossRef" href="#fig3">fig. 3</a>), estas informaron de lisis masiva de epífisis femoral y acetábulo. Previamente a la implantación de prótesis total de cadera se realizó una biopsia, en la que se evidenció tejido fibroso con proliferación vascular, sin datos de malignidad, que reafirmó la sospecha previa de enfermedad de Gorham.</p><elsevierMultimedia ident="fig0005"></elsevierMultimedia><elsevierMultimedia ident="fig0010"></elsevierMultimedia><elsevierMultimedia ident="fig3"></elsevierMultimedia><p id="par0010" class="elsevierStylePara elsevierViewall">La enfermedad de Gorham es una entidad rara e infrecuente. Es posible que tenga alguna relación con la linfangiomatosis. En ella se produce una destrucción progresiva de hueso por proliferación de tejido vascular y osteoclastos. La clínica más frecuente que suele producir es dolor y fractura patológica. 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