Actualización en el tratamiento de la alopecia androgénica | Piel. Formación continuada en dermatología

array:22 ["pii" => "S0213925120303087" "issn" => "02139251" "doi" => "10.1016/j.piel.2020.05.012" "estado" => "S300" "fechaPublicacion" => "2021-06-01" "aid" => "2104" "copyrightAnyo" => "2020" "documento" => "article" "crossmark" => 1 "subdocumento" => "sco" "cita" => "Piel. 2021;36:408-18" "abierto" => array:3 [ "ES" => false "ES2" => false "LATM" => false ] "gratuito" => false "lecturas" => array:1 [ "total" => 0 ] "itemSiguiente" => array:17 [ "pii" => "S0213925120303701" "issn" => "02139251" "doi" => "10.1016/j.piel.2020.06.014" "estado" => "S300" "fechaPublicacion" => "2021-06-01" "aid" => "2141" "documento" => "article" "crossmark" => 1 "subdocumento" => "crp" "cita" => "Piel. 2021;36:419-20" "abierto" => array:3 [ "ES" => false "ES2" => false "LATM" => false ] "gratuito" => false "lecturas" => array:1 [ "total" => 0 ] "es" => array:11 [ "idiomaDefecto" => true "cabecera" => "Carta clínica" "titulo" => "Neuroma solitario circunscrito en el glande" "tienePdf" => "es" "tieneTextoCompleto" => "es" "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "419" "paginaFinal" => "420" ] ] "titulosAlternativos" => array:1 [ "en" => array:1 [ "titulo" => "Solitary circumscribed neuroma in glans penis" ] ] "contieneTextoCompleto" => array:1 [ "es" => true ] "contienePdf" => array:1 [ "es" => true ] "resumenGrafico" => array:2 [ "original" => 0 "multimedia" => array:8 [ "identificador" => "f0005" "etiqueta" => "Figura 1" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr1.jpeg" "Alto" => 1691 "Ancho" => 1614 "Tamanyo" => 240948 ] ] "detalles" => array:1 [ 0 => array:3 [ "identificador" => "al0005" "detalle" => "Figura " "rol" => "short" ] ] "descripcion" => array:1 [ "es" => "Pápula color piel aislada en el glande." ] ] ] "autores" => array:1 [ 0 => array:2 [ "autoresLista" => "Alba López Valle, Daniel Falkenhain López, María Concepción Garrido Ruiz, Verónica Monsálvez Honrubia" "autores" => array:4 [ 0 => array:2 [ "nombre" => "Alba" "apellidos" => "López Valle" ] 1 => array:2 [ "nombre" => "Daniel" "apellidos" => "Falkenhain López" ] 2 => array:2 [ "nombre" => "María Concepción" "apellidos" => "Garrido Ruiz" ] 3 => array:2 [ "nombre" => "Verónica" "apellidos" => "Monsálvez Honrubia" ] ] ] ] ] "idiomaDefecto" => "es" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0213925120303701?idApp=UINPBA00004N" "url" => "/02139251/0000003600000006/v1_202106100533/S0213925120303701/v1_202106100533/es/main.assets" ] "itemAnterior" => array:17 [ "pii" => "S021392512030472X" "issn" => "02139251" "doi" => "10.1016/j.piel.2020.12.003" "estado" => "S300" "fechaPublicacion" => "2021-06-01" "aid" => "2193" "documento" => "article" "crossmark" => 1 "subdocumento" => "crp" "cita" => "Piel. 2021;36:406-7" "abierto" => array:3 [ "ES" => false "ES2" => false "LATM" => false ] "gratuito" => false "lecturas" => array:1 [ "total" => 0 ] "es" => array:10 [ "idiomaDefecto" => true "cabecera" => "Caso para el diagnóstico. Solución" "titulo" => "Placas necróticas en los miembros inferiores. Diagnóstico y comentario" "tienePdf" => "es" "tieneTextoCompleto" => "es" "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "406" "paginaFinal" => "407" ] ] "titulosAlternativos" => array:1 [ "en" => array:1 [ "titulo" => "Necrotic plaques on thighs. Diagnosis and comment" ] ] "contieneTextoCompleto" => array:1 [ "es" => true ] "contienePdf" => array:1 [ "es" => true ] "autores" => array:1 [ 0 => array:2 [ "autoresLista" => "Nicolás Silvestre Torner, Hirune Cembrero Saralegui, María Dorado Fernández" "autores" => array:3 [ 0 => array:2 [ "nombre" => "Nicolás" "apellidos" => "Silvestre Torner" ] 1 => array:2 [ "nombre" => "Hirune" "apellidos" => "Cembrero Saralegui" ] 2 => array:2 [ "nombre" => "María" "apellidos" => "Dorado Fernández" ] ] ] ] ] "idiomaDefecto" => "es" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S021392512030472X?idApp=UINPBA00004N" "url" => "/02139251/0000003600000006/v1_202106100533/S021392512030472X/v1_202106100533/es/main.assets" ] "es" => array:13 [ "idiomaDefecto" => true "cabecera" => "Terapéutica dermatológica" "titulo" => "Actualización en el tratamiento de la alopecia androgénica" "tieneTextoCompleto" => true "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "408" "paginaFinal" => "418" ] ] "autores" => array:1 [ 0 => array:4 [ "autoresLista" => "Alfonso Mogedas-Vegara, Eugènia Agut-Busquet, Miquel Ribera Pibernat" "autores" => array:3 [ 0 => array:4 [ "nombre" => "Alfonso" "apellidos" => "Mogedas-Vegara" "email" => array:1 [ 0 => "alfonso.mogedas@gmail.com" ] "referencia" => array:2 [ 0 => array:2 [ "etiqueta" => "a" "identificador" => "af0005" ] 1 => array:2 [ "etiqueta" => "*" "identificador" => "cr0005" ] ] ] 1 => array:3 [ "nombre" => "Eugènia" "apellidos" => "Agut-Busquet" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "b" "identificador" => "af0010" ] ] ] 2 => array:3 [ "nombre" => "Miquel" "apellidos" => "Ribera Pibernat" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "c" "identificador" => "af0015" ] ] ] ] "afiliaciones" => array:3 [ 0 => array:3 [ "entidad" => "Servicio de Cirugía Oral y Maxilofacial, Hospital Universitari Parc Taulí, Universidad Autónoma de Barcelona, Sabadell, España" "etiqueta" => "a" "identificador" => "af0005" ] 1 => array:3 [ "entidad" => "Servicio de Dermatología, Hospital de la Santa Creu i Sant Pau, Universidad Autónoma de Barcelona, Barcelona, España" "etiqueta" => "b" "identificador" => "af0010" ] 2 => array:3 [ "entidad" => "Servicio de Dermatología, Hospital Universitari Parc Taulí, Universidad Autónoma de Barcelona, Sabadell, España" "etiqueta" => "c" "identificador" => "af0015" ] ] "correspondencia" => array:1 [ 0 => array:3 [ "identificador" => "cr0005" "etiqueta" => "⁎" "correspondencia" => "Autor para correspondencia." ] ] ] ] "titulosAlternativos" => array:1 [ "en" => array:1 [ "titulo" => "Update on the treatment of androgenic alopecia" ] ] "textoCompleto" => "IntroducciónLa alopecia androgénica (AGA) es la forma más frecuente de pérdida de cabello. La edad de aparición es variable, aunque lo más frecuente es que aparezca durante la pubertad en los hombres y un poco más tarde en las mujeres. Su prevalencia y severidad suele ir aumentando con la edad en ambos sexos, estimándose en las series publicadas que aproximadamente afecta a un 70% de los varones caucásicos y entre el 30 y 50% de las mujeres<a class="elsevierStyleCrossRefs" href="#bb0005">1,2</a>.Se considera un trastorno multifactorial causado por la interacción de múltiples genes, hormonas y factores medioambientales y cuya fisiopatología se encuentra influida por las alteraciones en el metabolismo de los andrógenos<a class="elsevierStyleCrossRefs" href="#bb0015">3,4</a>.Histopatológicamente se produce una miniaturización progresiva del folículo en la que los pelos terminales gruesos y pigmentados se van transformando en pelos vellosos. Encontramos una seudohiperplasia de las glándulas sebáceas que parecen de mayor tamaño al compararlas con los folículos miniaturizados. Debido al incremento de los niveles de dihidrotestosterona, se produce una disminución de la fase de anágeno y un incremento de la de telógeno<a class="elsevierStyleCrossRefs" href="#bb0025">5,6</a>.Puede afectar tanto a la vertiente cosmética como a la esfera psicosocial de las personas, pudiendo llegar a deteriorar su calidad de vida. Por este motivo los pacientes tienden a buscar alguna solución<a class="elsevierStyleCrossRefs" href="#bb0035">7,8</a>.Existe en la actualidad una gran variedad de tratamientos para la AGA, pero al día de hoy no se dispone de una cura definitiva<a class="elsevierStyleCrossRefs" href="#bb0045">9,10</a>.El objetivo de este trabajo es realizar una actualización de los últimos artículos publicados relativos al tratamiento de la AGA con el fin de determinar la eficacia de las diferentes técnicas, así como de las complicaciones asociadas.Material y métodosEn esta revisión se realizó una búsqueda en MEDLINE (PubMed) de los estudios publicados en los años 2018 y 2019. La revisión se actualizó con fecha de 21 de septiembre de 2019. En la estrategia de búsqueda se utilizaron las siguientes palabras claves: ((«alopecia»[MeSH Terms] OR «alopecia»[All Fields] OR «baldness»[All Fields]) OR «hair loss»[All Fields] AND ((«male»[MeSH Terms] OR «male»[All Fields]) OR («female»[MeSH Terms] OR «female»[All Fields]) OR («men»[MeSH Terms] OR «men»[All Fields]) OR («men»[MeSH Terms] OR «men»[All Fields] OR «man»[All Fields]) OR («women»[MeSH Terms] OR «women»[All Fields] OR «woman»[All Fields]) OR («women»[MeSH Terms] OR «women»[All Fields])) AND androgenetic[All Fields]) OR (androgenetic[All Fields] AND («alopecia»[MeSH Terms] OR «alopecia»[All Fields])).Para controlar los posibles sesgos, 2 revisores independientes (Alfonso Mogedas Vegara y Eugènia Agut Busquets) evaluaron los títulos y los resúmenes de los artículos. Si no se tenía la seguridad si el artículo podía cumplir los criterios de inclusión, se revisó el artículo completo. Se excluyeron las opiniones de los expertos. Cuando se identificaron resultados duplicados del mismo estudio, solo se incluyeron los más recientes. Se evaluaron los artículos completos y las diferencias entre ambos revisores se resolvieron mediante discusión hasta que se llegó a un acuerdo.Los criterios de inclusión fueron: a) Estudios con series de pacientes que presentan AGA, y b) Estudios que determinan la eficacia de tratamientos médicos o quirúrgicos para el tratamiento de la AGA; y los de exclusión: a) Estudios sobre otro tipo de alopecia distinta de la AGA, b) Estudios sobre el tratamiento de la AGA pero que no reflejen la eficacia de las técnicas empleadas, c) Revisiones de la literatura, revisiones sistemáticas y metaanálisis, d) Estudios duplicados, e) Estudios realizados en animales, f) Estudios experimentales en laboratorio, g) Estudios de cohortes con menos de 10 pacientes, h) Artículos publicados en otras lenguas distintas al inglés, alemán, francés, italiano y español, i) Cartas y abstracts, j) Encuestas y k) Libros y capítulos de libros.La información recogida en cada artículo fue la siguiente: a) Primer autor, b) Tipo de tratamiento o intervención realizada, c) Número de pacientes tratados, d) Grado de alopecia masculina (escala de Hamilton-Norwood) o femenina (escala de Ludwig), e) Tiempo de seguimiento. Herramientas para medir la respuesta, f) Resultados estadísticamente significativos (p < 0,05) y g) Efectos secundarios o complicaciones.ResultadosLa búsqueda inicial en MEDLINE tuvo como resultado 207 artículos. El estudio inicial de títulos y abstracts permitió eliminar 140 artículos, dejando 67 artículos para ser examinados en profundidad. Un total de 31 artículos cumplían los criterios y fueron incluidos para la revisión final.Los artículos fueron clasificados en 4 grupos: 1.) Medicina oral y tópica (10 artículos), 2.) Medicina regenerativa (plasma rico en plaquetas [PRP] y células madre) (13 artículos), 3.) Aparatología (7 artículos) y 4.) Trasplante capilar (1 artículo).Los 10 artículos (32,25%) sobre los tratamientos orales o tópicos para el manejo de la AGA<a class="elsevierStyleCrossRefs" href="#bb0055">11–20</a> se resumen en la <a class="elsevierStyleCrossRefs" href="#t0005">tablas 1 y 2</a>. Los 13 artículos (41,93%) que versaban sobre tratamientos regenerativos con PRP y células madre se presentan en las <a class="elsevierStyleCrossRefs" href="#t0015">tablas 3 y 4</a> respectivamente<a class="elsevierStyleCrossRefs" href="#bb0105">21–33</a>. Los 7 artículos (22,58%) se incluyeron en el grupo de tratamientos de la AGA mediante aparatología médica<a class="elsevierStyleCrossRefs" href="#bb0170">34–40</a> y sus resultados se exponen en la <a class="elsevierStyleCrossRef" href="#t0025">tabla 5</a>. Un artículo (3,22%) estaba relacionado con el trasplante capilar<a class="elsevierStyleCrossRef" href="#bb0205">41</a> y se muestra en la <a class="elsevierStyleCrossRef" href="#t0030">tabla 6</a>.<elsevierMultimedia ident="t0005"></elsevierMultimedia><elsevierMultimedia ident="t0010"></elsevierMultimedia><elsevierMultimedia ident="t0015"></elsevierMultimedia><elsevierMultimedia ident="t0020"></elsevierMultimedia><elsevierMultimedia ident="t0025"></elsevierMultimedia><elsevierMultimedia ident="t0030"></elsevierMultimedia>DiscusiónEn la actualidad los únicos tratamientos aprobados por la Food and drug administration (FDA) para el tratamiento de la AGA son el minoxidil tópico (MT), la finasterida oral (FO) y la terapia con láser de baja potencia (LLLT), siendo la FO, para hombres, y el MT, para hombres y mujeres, los que ofrecen el mayor nivel de evidencia en términos de eficacia y seguridad<a class="elsevierStyleCrossRef" href="#bb0210">42</a>.El minoxidil aplicado tópicamente en concentraciones del 2-5% es un fármaco aprobado por la FDA para el tratamiento de la AGA de patrón masculino y femenino. Además, se emplea de forma off-label para el tratamiento de otros tipos de alopecia<a class="elsevierStyleCrossRef" href="#bb0220">44</a>. Su mecanismo de acción no ha sido aclarado, aunque se le atribuye su efecto a un estímulo sobre la neoangiogénesis que produce un aumento de la fase anágena y una disminución de la telógena<a class="elsevierStyleCrossRefs" href="#bb0080">16,43</a>.La respuesta a la terapia tópica puede ser lenta y se suelen necesitar de 3 a 6 meses para objetivar las mejorías. Cuando cesa el tratamiento, no solo deja de crecer el cabello, sino que se suele producir un efluvio telógeno de los cabellos dependientes de minoxidil a los 4-6 meses<a class="elsevierStyleCrossRef" href="#bb0225">45</a>.Se ha evaluado la eficacia y la seguridad del MT al 10% en comparación al 5% para el tratamiento de la AGA en hombres, concluyendo que el MT al 5% es moderadamente superior al MT al 10% en el incremento del crecimiento capilar, además de presentar menos efectos secundarios<a class="elsevierStyleCrossRef" href="#bb0090">18</a>.La respuesta al MT puede predecirse mediante el test de respuesta a la sulfotransferasa, que es la enzima que se encarga de activar al minoxidil en su forma activa (sulfato de minoxidil). Debe tenerse en cuenta a los pacientes que toman aspirina, ya que a dosis de 75 mg puede disminuir la eficacia del MT por inhibir la actividad de la sulfotransferasa<a class="elsevierStyleCrossRef" href="#bb0230">46</a>. Por el contrario, el tratamiento con retinoides como la tretinoína tópica es capaz de potenciar la actividad de la sulfotransferasa<a class="elsevierStyleCrossRef" href="#bb0235">47</a>.En cuanto al minoxidil administrado por vía oral (MO) diversos autores han intentado esclarecer su utilidad en el tratamiento de la AGA. En cuanto a las dosis propuestas para los hombres, varían entre los 0,25 mg hasta los 5 mg, presentando un perfil de seguridad similar<a class="elsevierStyleCrossRefs" href="#bb0240">48,49</a>. También se ha estudiado su efecto a dosis de 0,25 mg al día combinado con 25 mg de espironolactona para el tratamiento de la AGA en las mujeres<a class="elsevierStyleCrossRef" href="#bb0250">50</a>. Ramos et al. no encuentran diferencias estadísticamente significativas en la eficacia y el perfil de seguridad cuando comparan en un grupo de 50 mujeres con AGA, el tratamiento con 1 mg de MO o con MT al 5%<a class="elsevierStyleCrossRef" href="#bb0255">51</a>.La finasterida es un antagonista selectivo de los receptores tipo 2 de la 5-alfa-reductasa y está aprobada por la FDA para el tratamiento de la AGA en hombres. Inhibe la conversión de testosterona en dihidrotestosterona, la cual está relacionada con la miniaturización del folículo. Su uso a largo plazo puede incrementar en un 30% el número de cabellos, pese a asociarse a un 1,5% de riesgo de disfunción eréctil<a class="elsevierStyleCrossRef" href="#bb0260">52</a>. Los estudios recogidos en la literatura muestran una mejoría a largo plazo del 93-100% de los pacientes, lo que sugiere que puede ser empleada para prevenir la progresión de la AGA en la mayoría de los casos<a class="elsevierStyleCrossRef" href="#bb0065">13</a>. Otros autores no encuentran relación entre su uso y la aparición de alteraciones sexuales<a class="elsevierStyleCrossRef" href="#bb0265">53</a>.En cuanto a su uso en mujeres, no está aprobada por la FDA ya que se clasifica como un fármaco de categoría X por el riesgo de desarrollar en mujeres en edad fértil, alteraciones en los genitales de los fetos masculinos. Por este motivo su uso para el tratamiento de la AGA de patrón femenino se considera off-label y las mujeres que lo tomen deben de estar informadas sobre el riesgo teratogénico que implica<a class="elsevierStyleCrossRefs" href="#bb0270">54,55</a>. Se discute qué dosis es la más eficaz y parece que con 2,5 mg al día se consigue la misma eficacia que con 5 mg diarios, presentando un perfil de seguridad similar<a class="elsevierStyleCrossRef" href="#bb0070">14</a>.La dutasterida es otro antagonista de la 5-alfa-reductasa de tipo 1 y 2 el cual parece presentar mejor eficacia con un perfil de seguridad similar a la finasterida<a class="elsevierStyleCrossRef" href="#bb0280">56</a>.En la revisión sistemática efectuada por Lee et al. se plantea como alternativa el uso tópico de la finasterida, la cual presenta un perfil de seguridad y resultados preliminares buenos, pero estos deben de ser confirmados con más estudios para poder esclarecer su utilidad<a class="elsevierStyleCrossRef" href="#bb0285">57</a>.Con el fin de conseguir la máxima eficacia y satisfacción del paciente, encontramos estudios en los que se aplican terapias combinadas por vía tópica, oral e inyectable como el de Tanaka et al. sobre 18.918 varones, en el que emplea 1 mg diario de finasterida por vía oral, 2,5 mg de MO y una solución de MT al 5%, ambas administradas 2 veces al día junto a inyecciones mensuales sobre el cuero cabelludo de un concentrado variado durante más de 6 meses, obteniendo una mejoría clínica significativa y un grado de satisfacción a los 6 y 12 meses postratamiento del 90 y 86% respectivamente. Sus resultados están limitados al no emplear un grupo control y no comparar diferentes dosis<a class="elsevierStyleCrossRef" href="#bb0060">12</a>.En cuanto a los tratamientos tópicos para el tratamiento de la AGA se presenta un estudio sobre 67 pacientes tratados con cetirizina, un inhibidor de la prostaglandina D2 (PGD2), presentando un incremento en la densidad total del cabello, la densidad del cabello terminal y el diámetro, junto con una reducción del pelo velloso sin presentar efectos adversos. Se ha relacionado a las prostaglandinas E y F2-α (PGE, PGF2-α) con un papel positivo en el crecimiento capilar, mientras que la PGD2 parece que tiene un efecto inhibitorio del mismo<a class="elsevierStyleCrossRef" href="#bb0100">20</a>. El latanoprost es un análogo de la PGF2-α empleado para favorecer el crecimiento de las pestañas<a class="elsevierStyleCrossRef" href="#bb0290">58</a>. Se ha presentado un preparado tópico para el tratamiento de la AGA que presenta un componente que es el ácido dihomo-γ-linolénico el cual se ha visto que puede incrementar los niveles de PDG1 y PGE2<a class="elsevierStyleCrossRef" href="#bb0080">16</a>.La cafeína funciona disminuyendo la actividad local de la fosfodiesterasa e incrementando el aporte de oxígeno al folículo. Los champús y soluciones con cafeína se han empleado con mínimos efectos adversos para el tratamiento de la AGA con resultados prometedores<a class="elsevierStyleCrossRefs" href="#bb0085">17,59</a>.La hipótesis de que los suplementos probióticos pueden favorecer el riego sanguíneo del cuero cabelludo y por ello promover el crecimiento capilar ha sido publicada por el grupo de Park et al.<a class="elsevierStyleCrossRef" href="#bb0055">11</a>.El mecanismo de acción de los champús empleados para el tratamiento de la AGA como el CG210, parece relacionado con el incremento del Bcl-2 y del colágeno perifolicular<a class="elsevierStyleCrossRef" href="#bb0095">19</a>, mientras que otros artículos lo atribuyen al incremento de células de Langerhans CD1A+, Ki-67 y Bcl-2<a class="elsevierStyleCrossRef" href="#bb0300">60</a>.En cuanto al PRP, la literatura lo define como un procedimiento off-label y mínimamente invasivo para el tratamiento de la AGA que puede realizarse en la consulta. Es un producto biológico constituido por plaquetas autólogas en un pequeño volumen de plasma y contiene más de 20 factores de crecimiento. Los más importantes que se han relacionado con el crecimiento capilar son el factor de crecimiento derivado de las plaquetas, el factor de crecimiento transformante beta, el factor de crecimiento vascular endotelial, el factor de crecimiento insulínico tipo 1 y el factor de crecimiento de fibroblastos (FGF)<a class="elsevierStyleCrossRefs" href="#bb0130">26–28</a>.La mayoría de los estudios hipotetizan sobre las relaciones que existen entre el crecimiento capilar y los factores de crecimiento que son liberados por las plaquetas, asumiendo que estos inducen la diferenciación de las células madre, prolongan la supervivencia de las células de la papila dérmica y estimulan tanto la neoangiogénesis como la transición de la fase de telógeno a la de anágeno<a class="elsevierStyleCrossRefs" href="#bb0110">22–24,27,61,62</a>.Existe contradicción en cuanto a la relación entre los factores de crecimiento, las plaquetas y la eficacia del PRP. Mientras que algunos autores han relacionado a los pacientes con mayor recuento plaquetario en la preparación de PRP con una mejor respuesta clínica en comparación con los pacientes que presentaban un recuento plaquetario menor<a class="elsevierStyleCrossRef" href="#bb0135">27</a>, otros autores por el contrario no encuentran relación entre la mejoría clínica y los niveles del factor de crecimiento epidérmico (EGF), el factor de crecimiento derivado de las plaquetas, el factor de crecimiento vascular endotelial y el número de plaquetas<a class="elsevierStyleCrossRef" href="#bb0105">21</a>.Diversos autores han descrito el poder antiinflamatorio y la capacidad de disminuir el sebo del PRP como posibles factores determinantes de su eficacia. Esta última característica estaría relacionada con la regulación positiva de la vía de las Wnt/β-cateninas<a class="elsevierStyleCrossRefs" href="#bb0140">28,63</a>.Gentile et al. muestran su experiencia con el sistema de inyección mecánico para el PRP, empleando una pistola y concluyen que es una técnica reproducible, que produce menos dolor en comparación con la técnica de inyección manual pero que requiere de cierta experiencia y prolonga la duración del procedimiento<a class="elsevierStyleCrossRef" href="#bb0125">25</a>.En la bibliografía consultada se relaciona la mejor respuesta al tratamiento con PRP a los pacientes que presentan menor severidad y duración de la AGA<a class="elsevierStyleCrossRefs" href="#bb0120">24,28</a>. Incluso en estadios avanzados podría ser inefectivo<a class="elsevierStyleCrossRef" href="#bb0320">64</a>. La efectividad del PRP se pone en entredicho en algunos artículos en los que se equipara la mejoría con la del grupo que recibió placebo<a class="elsevierStyleCrossRef" href="#bb0130">26</a>.La mayoría de los estudios de AGA y PRP presentan buena satisfacción por parte del paciente y mejoras objetivas en relación al incremento del diámetro y de la densidad capilar<a class="elsevierStyleCrossRefs" href="#bb0325">65–67</a>. Es una técnica asociada a una baja tasa de complicaciones. Las más frecuentes son el dolor y el sangrado leve<a class="elsevierStyleCrossRefs" href="#bb0115">23,24,26–28,30</a>. En la revisión realizada encontramos que varios artículos no recogen las complicaciones de los pacientes pudiendo llegar a infravalorarlas<a class="elsevierStyleCrossRefs" href="#bb0105">21,22,25</a>.La mayoría de los artículos publicados al respecto del tratamiento de la AGA con PRP no son ensayos clínicos aleatorizados, tienen tamaños muestrales pequeños, los pacientes presentan diferentes grados de intensidad en la escala de Hamilton-Norwood o Ludwig y encontramos diferentes métodos de preparación del PRP. Algunos permiten que los pacientes continúen con su tratamiento habitual para la alopecia y otros no. Los resultados en ocasiones se valoran de forma cuantitativa y en otras de forma cualitativa. La metodología y la composición final de los preparados de PRP es inconsistente e insuficiente para comparar los estudios y su eficacia<a class="elsevierStyleCrossRefs" href="#bb0105">21–30,68</a>.Se debería establecer un sistema de nomenclatura definido y validado para caracterizar las diferentes composiciones del PRP para así facilitar la comunicación, la interpretación y la comparación de los resultados. Algunos autores precisan que según la FDA, para poder cuantificar el crecimiento capilar, se debería realizar un recuento tricográfico, y exponen que actualmente no existen estudios bien elaborados al respecto, con lo que no se puede valorar la eficacia de la técnica<a class="elsevierStyleCrossRefs" href="#bb0345">69,70</a>.En general, para poder consolidar la utilización del PRP en el tratamiento de la AGA y determinar su verdadera eficacia, se necesitaría la realización de más ensayos clínicos aleatorizados, mejorar el diseño de los mismos incluyendo un mayor número de pacientes, realizando determinaciones objetivas con periodos de seguimiento de mayor duración<a class="elsevierStyleCrossRef" href="#bb0105">21</a>.Recientemente encontramos estudios sobre el uso de las células madre para el tratamiento de la AGA. Elmaadawi et al. presentan un estudio en el que infiltran células mononucleares derivadas de la médula ósea a 10 pacientes y células madre foliculares a otros 10 pacientes. A los 6 meses los 2 tratamientos produjeron un incremento del diámetro capilar y de la densidad por cm<a class="elsevierStyleCrossRef" href="#bb0010">2</a> sin diferencias significativas entre ellos. Concluyen que la terapia con células madre es un tratamiento prometedor, pero todavía presenta inconvenientes como el precio, el tiempo de procesado, y la necesidad de unas instalaciones específicas con profesionales especializados en su manejo<a class="elsevierStyleCrossRef" href="#bb0160">32</a>.Gentile et al. evalúan la efectividad del PRP y los microinjertos con células madre mesenquimales foliculares en un grupo de 78 pacientes y revisan las vías biomoleculares implicadas. Concluyen que el incremento de la señalización en la vía de las Wnt en las células de la papila dérmica es uno de los principales implicados en el crecimiento capilar. Las células de la papila dérmica cuando se cultivan en un medio de crecimiento suplementado con PRP muestran niveles incrementados de Bcl-2 y FGF-7, de proteínas ERK (quinasas reguladas por señales extracelulares) y Akt activadas, y permiten una regulación positiva de las β-catenina. Todo esto se ha relacionado positivamente con el crecimiento y la proliferación capilar<a class="elsevierStyleCrossRef" href="#bb0165">33</a>.Se pueden dividir los láseres que se emplean para el tratamiento de la AGA en fotobiomoduladores o LLLT y en láseres fraccionales.Dentro de los fotobiomoduladores encontramos el Hair Max Lasercomb ® (aprobado por la FDA), el láser de He-Ne y el láser excímer. Los LLLT están aprobados por la FDA para el tratamiento de la AGA de patrón masculino y femenino desde 2007 y 2011 respectivamente. Habitualmente emplean una luz roja con longitudes de onda que van de 635 a 678 nm y contienen entre 51 y 272 láseres de diodo, con una potencia que varía de 2 a 20 mW por diodo. Los protocolos que se recomiendan para su uso varían entre 10 y 30 min y de 2 a 7 sesiones semanales<a class="elsevierStyleCrossRef" href="#bb0355">71</a>. Actualmente se especula que los mecanismos por los que se estimula el crecimiento capilar pueden ser a través de la activación de las Wnt/β-cateninas y la vía del ERK. El incremento del diámetro capilar podría deberse al incremento de la producción de adenosina trifosfato, reduciendo la inflamación local y mejorando la vascularización de la zona<a class="elsevierStyleCrossRef" href="#bb0225">45</a>. Pachchaprateep et al. realizan un estudio proteinómico para medir la respuesta biológica de la papila dérmica en 4 pacientes afectos de AGA antes y después de ser tratados mediante LLLT, obtienen una mejoría estadísticamente significativa en el incremento de cabellos terminales y totales y del índice de masa capilar tras 24 semanas de tratamiento, demostrando el efecto estimulante del LLLT en la papila dérmica<a class="elsevierStyleCrossRef" href="#bb0360">72</a>. Los estudios que encontramos en la bibliografía concluyen que puede ser un método eficaz para el tratamiento de la AGA tanto en monoterapia como coadyuvante con otros tratamientos, sin encontrar diferencias de efectividad entre hombres y mujeres<a class="elsevierStyleCrossRefs" href="#bb0170">34,37</a>.Por otro lado, encontramos los láseres fraccionales como el láser 1550 nm Erbium-glass (Er-glass), el láser 2940 nm Erbium:YAG y el láser de CO2. Pese a que no se conoce su exacto mecanismo de funcionamiento, se postula que puede ser debido al proceso de cicatrización tras el trauma inducido y a un incremento en la vía de las Wnt/β-catenina. Se han empleado como tratamientos eficaces y seguros para varios tipos de alopecia incluyendo la AGA<a class="elsevierStyleCrossRef" href="#bb0365">73</a>. Los resultados del tratamiento con el láser Er-glass y MT al 5% en comparación con MT 5% en monoterapia son superiores en cuanto al incremento de la densidad y del diámetro capilar. Esto puede ser debido a que el láser Er-glass favorece el crecimiento capilar y por otro lado facilita la penetración transdérmica del MT al 5%<a class="elsevierStyleCrossRef" href="#bb0195">39</a>. Meephansan et al. no encuentran relación tras la utilización del láser de Er-glass para el tratamiento de la AGA en los niveles de IGF-1 y los de Wnt104 mRNA 24 h después de la irradiación, por lo que debe de haber otros factores relacionados con su efecto sobre el crecimiento capilar<a class="elsevierStyleCrossRef" href="#bb0180">36</a>. Todavía encontramos pocos estudios, por lo que sería deseable la realización de ensayos clínicos aleatorizados, con mayores tiempos de seguimiento para poder establecer los parámetros óptimos de tratamiento y sus indicaciones<a class="elsevierStyleCrossRefs" href="#bb0365">73,74</a>.La radiofrecuencia fraccionada es otro de los dispositivos basados en la energía que se ha empleado para el tratamiento de la AGA. Se postula que su posible mecanismo de acción es a través de la activación de FC como el IGF-1 (factor de crecimiento similar a la insulina), FGF 5 y 7 o a través de la activación de la vía de las proteínas Wnt<a class="elsevierStyleCrossRef" href="#bb0190">38</a>.El microneedling podría ser de utilidad en casos refractarios, presentando escasos efectos secundarios y podría facilitar la penetración transdérmica de diversos fármacos<a class="elsevierStyleCrossRef" href="#bb0200">40</a>.La carboxiterapia puede ser de utilidad como tratamiento adyuvante de la AGA. En el estudio de Doghaim et al. durante el seguimiento la mayoría de los pacientes muestran empeoramiento después de suspender las sesiones, aunque estaban mejor que al principio del tratamiento<a class="elsevierStyleCrossRef" href="#bb0175">35</a>.El trasplante capilar es la opción quirúrgica para el tratamiento de la AGA que se fundamenta en extraer las unidades foliculares de la zona occipital y temporal y colocarlas en aquellas zonas que necesiten una mayor densidad. Es importante realizar una correcta selección de los pacientes candidatos a este tipo de procedimientos, así como de las unidades foliculares de la zona donante y una técnica de disección folicular exquisita. Li KT et al. muestran su experiencia en sesiones de follicular unit extraction de 3000-6000 unidades foliculares en una muestra de 273 hombres, con unas tasas de supervivencia del 93,5-96,6% y una tasa de satisfacción del 81%<a class="elsevierStyleCrossRef" href="#bb0205">41</a>.ConclusionesLos únicos tratamientos aprobados por la FDA para el tratamiento de la AGA son el MT, la FO y los LLLT, siendo la FO, para los hombres, y el MT, para los hombres y las mujeres, los que ofrecen el mayor nivel de evidencia en términos de eficacia y seguridad.Disponemos en la literatura de otros tratamientos como el PRP, la terapia con células madre, diversos tratamientos tópicos y orales y diversa aparatología. En su mayoría parecen ser técnicas eficaces y seguras para el tratamiento de la AGA, pero se necesita la realización de más estudios y ensayos clínicos aleatorizados con periodos de seguimiento más prolongados para poder concluir su eficacia y seguridad, y poder establecer protocolos estandarizados de tratamiento.FinanciaciónLa realización de este trabajo de fin de máster no ha recibido ningún tipo de financiación.Conflicto de interesesEl autor declara no tener conflicto de intereses." "textoCompletoSecciones" => array:1 [ "secciones" => array:8 [ 0 => array:2 [ "identificador" => "s0005" "titulo" => "Introducción" ] 1 => array:2 [ "identificador" => "s0010" "titulo" => "Material y métodos" ] 2 => array:2 [ "identificador" => "s0015" "titulo" => "Resultados" ] 3 => array:2 [ "identificador" => "s0020" "titulo" => "Discusión" ] 4 => array:2 [ "identificador" => "s0025" "titulo" => "Conclusiones" ] 5 => array:2 [ "identificador" => "s0030" "titulo" => "Financiación" ] 6 => array:2 [ "identificador" => "s0035" "titulo" => "Conflicto de intereses" ] 7 => array:1 [ "titulo" => "Bibliografía" ] ] ] "pdfFichero" => "main.pdf" "tienePdf" => true "multimedia" => array:6 [ 0 => array:8 [ "identificador" => "t0005" "etiqueta" => "Tabla 1" "tipo" => "MULTIMEDIATABLA" "mostrarFloat" => true "mostrarDisplay" => false "detalles" => array:1 [ 0 => array:3 [ "identificador" => "al0005" "detalle" => "Tabla " "rol" => "short" ] ] "tabla" => array:2 [ "leyenda" => "BASP: basic and specific classification; Ca: casos; Co: controles; H: hombres; HN: Hamilton-Norwood; IGA: investigator's global assessment; L: Ludwig; M: mujeres; N: número de pacientes; TSS: triple scope system; vo: vía oral; X: no recogido." "tablatextoimagen" => array:1 [ 0 => array:2 [ "tabla" => array:1 [ 0 => """ <table border="0" frame="\n \t\t\t\t\tvoid\n \t\t\t\t" class=""><thead title="thead"><tr title="table-row"><th class="td" title="\n \t\t\t\t\ttable-head\n \t\t\t\t " align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t" scope="col" style="border-bottom: 2px solid black">Autor \t\t\t\t\t\t\n \t\t\t\t\t\t</th><th class="td" title="\n \t\t\t\t\ttable-head\n \t\t\t\t " align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t" scope="col" style="border-bottom: 2px solid black">Medicación/intervención \t\t\t\t\t\t\n \t\t\t\t\t\t</th><th class="td" title="\n \t\t\t\t\ttable-head\n \t\t\t\t " align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t" scope="col" style="border-bottom: 2px solid black">Pacientes/escala/seguimiento \t\t\t\t\t\t\n \t\t\t\t\t\t</th><th class="td" title="\n \t\t\t\t\ttable-head\n \t\t\t\t " align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t" scope="col" style="border-bottom: 2px solid black">Evaluación \t\t\t\t\t\t\n \t\t\t\t\t\t</th><th class="td" title="\n \t\t\t\t\ttable-head\n \t\t\t\t " align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t" scope="col" style="border-bottom: 2px solid black">P < 0,05 \t\t\t\t\t\t\n \t\t\t\t\t\t</th><th class="td" title="\n \t\t\t\t\ttable-head\n \t\t\t\t " align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t" scope="col" style="border-bottom: 2px solid black">Efectos secundariosn (%) \t\t\t\t\t\t\n \t\t\t\t\t\t</th></tr></thead><tbody title="tbody"><tr title="table-row"><td class="td-with-role" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t ; entry_with_role_rowhead rowgroup " rowspan="4" align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">Park DW, et al.<a class="elsevierStyleCrossRef" href="#bb0055">11</a></td><td class="td-with-role" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t ; entry_with_role_rowgroup " rowspan="4" align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">-Mogut 80 ml</td><td class="td-with-role" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t ; entry_with_role_rowgroup " rowspan="2" align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">-n = 46 (23 H, 23 M)</td><td class="td-with-role" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t ; entry_with_role_rowgroup " rowspan="4" align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">-TSS</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">Al 4 mes: \t\t\t\t\t\t\n \t\t\t\t</td><td class="td-with-role" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t ; entry_with_role_rowgroup " rowspan="4" align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">-No</td></tr><tr title="table-row"><td class="td-with-role" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t ; entry_with_role_rowgroup " rowspan="3" align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">-Incremento en el recuento y el grosor</td></tr><tr title="table-row"><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">-HN: II-V, L: I-III \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">-4 meses \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t ; entry_with_role_rowhead rowgroup " rowspan="11" align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">Tanaka Y, et al.<a class="elsevierStyleCrossRef" href="#bb0060">12</a></td><td class="td-with-role" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t ; entry_with_role_rowgroup " rowspan="11" align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">-Finasteride 1 mg vo + Minoxidil 2,5 mg vo y tópico al 5% + tratamiento inyectable</td><td class="td-with-role" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t ; entry_with_role_rowgroup " rowspan="3" align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">-n = 18.918 H-X</td><td class="td-with-role" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t ; entry_with_role_rowgroup " rowspan="2" align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">-Fotografía digital</td><td class="td-with-role" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t ; entry_with_role_rowgroup " rowspan="11" align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">-X</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">-n = 802 (4,2%) \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t ; entry_with_role_rowgroup " rowspan="3" align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">-Dolor leve: n = 651 (3,4%)</td></tr><tr title="table-row"><td class="td-with-role" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t ; entry_with_role_rowgroup " rowspan="9" align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">-Autoevaluación</td></tr><tr title="table-row"><td class="td-with-role" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t ; entry_with_role_rowgroup " rowspan="7" align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t"></td></tr><tr title="table-row"><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">-Sangrado leve: n = 56 (0,3%) \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">-Edema: n = 42 (0,22%) \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">-Mareos: n = 28 (0,15%) \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">-Picor: n = 7 (0,04%) \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">-Eritema: n = 4 (0,02%) \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t ; entry_with_role_rowgroup " rowspan="2" align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">-Disfunción eréctil: n = 14 (0,07%)</td></tr><tr title="table-row"><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">-Mínimo 18 meses \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t ; entry_with_role_rowhead rowgroup " rowspan="9" align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">Shin JW, et al.<a class="elsevierStyleCrossRef" href="#bb0065">13</a></td><td class="td-with-role" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t ; entry_with_role_rowgroup " rowspan="9" align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">-Finasteride 1 mg vo</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">-n = 126 H \t\t\t\t\t\t\n \t\t\t\t</td><td class="td-with-role" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t ; entry_with_role_rowgroup " rowspan="2" align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">-Fotografías</td><td class="td-with-role" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t ; entry_with_role_rowgroup " rowspan="5" align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">IGA score después de 6 meses, 1 y 2 años:-Tipo V presenta más mejora que F y el tipo básico</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">-n = 12 (9,5%) \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t ; entry_with_role_rowgroup " rowspan="2" align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">-BASP</td><td class="td-with-role" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t ; entry_with_role_rowgroup " rowspan="3" align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">-Disminución libido: n = 4 (3,1%)</td></tr><tr title="table-row"><td class="td-with-role" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t ; entry_with_role_rowgroup " rowspan="7" align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">-Evaluación dermatólogos</td></tr><tr title="table-row"><td class="td-with-role" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t ; entry_with_role_rowgroup " rowspan="6" align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">-5 años</td></tr><tr title="table-row"><td class="td-with-role" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t ; entry_with_role_rowgroup " rowspan="2" align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">-Disminución semen: n = 3 (2,4%)</td></tr><tr title="table-row"><td class="td-with-role" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t ; entry_with_role_rowgroup " rowspan="4" align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t"></td></tr><tr title="table-row"><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">-Disfunción eréctil: n = 3 (2,4%) \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">-Disfunción hepática: n = 1 (0,8%), \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">Problemas gastrointestinales: n = 1 (0,8%) \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t ; entry_with_role_rowhead rowgroup " rowspan="5" align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">Won YY, et al.<a class="elsevierStyleCrossRef" href="#bb0070">14</a></td><td class="td-with-role" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t ; entry_with_role_rowgroup " rowspan="5" align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">-Finasteride 2,5 mg vo</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">-n = 112 M \t\t\t\t\t\t\n \t\t\t\t</td><td class="td-with-role" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t ; entry_with_role_rowgroup " rowspan="2" align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">-Fotografías-Escala</td><td class="td-with-role" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t ; entry_with_role_rowgroup " rowspan="3" align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">-Asociación negativa entre la duración y la mejoría</td><td class="td-with-role" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t ; entry_with_role_rowgroup " rowspan="5" align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">-No</td></tr><tr title="table-row"><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">-L: I-III \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t ; entry_with_role_rowgroup " rowspan="3" align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">-17,6 ± 12,9 meses</td><td class="td-with-role" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t ; entry_with_role_rowgroup " rowspan="3" align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t"></td></tr><tr title="table-row"><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">-Asociación positiva entre la edad de aparición, la duración del tratamiento y la mejoría del scalp \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">-A menor Ludwig, mayor crecimiento capilar \t\t\t\t\t\t\n \t\t\t\t</td></tr></tbody></table> """ ] "imagenFichero" => array:1 [ 0 => "xTab2618528.png" ] ] ] ] "descripcion" => array:1 [ "es" => "Artículos seleccionados de tratamiento oral de la alopecia androgénica" ] ] 1 => array:8 [ "identificador" => "t0010" "etiqueta" => "Tabla 2" "tipo" => "MULTIMEDIATABLA" "mostrarFloat" => true "mostrarDisplay" => false "detalles" => array:1 [ 0 => array:3 [ "identificador" => "al0010" "detalle" => "Tabla " "rol" => "short" ] ] "tabla" => array:2 [ "leyenda" => "Ca: casos; Co: controles; DLQI: quality of life evaluation; H: hombres; HN: Hamilton-Norwood; L: Ludwig; M: mujeres; MT: minoxidil tópico; N: número de pacientes; X: no recogido." "tablatextoimagen" => array:1 [ 0 => array:2 [ "tabla" => array:1 [ 0 => """ <table border="0" frame="\n \t\t\t\t\tvoid\n \t\t\t\t" class=""><thead title="thead"><tr title="table-row"><th class="td" title="\n \t\t\t\t\ttable-head\n \t\t\t\t " align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t" scope="col" style="border-bottom: 2px solid black">Autor \t\t\t\t\t\t\n \t\t\t\t\t\t</th><th class="td" title="\n \t\t\t\t\ttable-head\n \t\t\t\t " align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t" scope="col" style="border-bottom: 2px solid black">Medicación/intervención \t\t\t\t\t\t\n \t\t\t\t\t\t</th><th class="td" title="\n \t\t\t\t\ttable-head\n \t\t\t\t " align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t" scope="col" style="border-bottom: 2px solid black">Pacientes/escala/seguimiento \t\t\t\t\t\t\n \t\t\t\t\t\t</th><th class="td" title="\n \t\t\t\t\ttable-head\n \t\t\t\t " align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t" scope="col" style="border-bottom: 2px solid black">Evaluación \t\t\t\t\t\t\n \t\t\t\t\t\t</th><th class="td" title="\n \t\t\t\t\ttable-head\n \t\t\t\t " align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t" scope="col" style="border-bottom: 2px solid black">P < 0,05 \t\t\t\t\t\t\n \t\t\t\t\t\t</th><th class="td" title="\n \t\t\t\t\ttable-head\n \t\t\t\t " align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t" scope="col" style="border-bottom: 2px solid black">Efectos secundariosn (%) \t\t\t\t\t\t\n \t\t\t\t\t\t</th></tr></thead><tbody title="tbody"><tr title="table-row"><td class="td-with-role" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t ; entry_with_role_rowhead rowgroup " rowspan="8" align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">Blume-Peytavi U, et al.<a class="elsevierStyleCrossRef" href="#bb0075">15</a></td><td class="td-with-role" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t ; entry_with_role_rowgroup " rowspan="6" align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">-Minoxidil 5%DC0120 vs. Alostil®</td><td class="td-with-role" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t ; entry_with_role_rowgroup " rowspan="4" align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">-220 H-HN: III-V-16 semanas</td><td class="td-with-role" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t ; entry_with_role_rowgroup " rowspan="3" align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">-Fototricograma (TrichoScan®)</td><td class="td-with-role" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t ; entry_with_role_rowgroup " rowspan="8" align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">-Mismo perfil de eficacia y seguridad</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">-Prurito \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">-Eritema \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t ; entry_with_role_rowgroup " rowspan="6" align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">-Sensación de quemazón-Descamación</td></tr><tr title="table-row"><td class="td-with-role" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t ; entry_with_role_rowgroup " rowspan="2" align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">-Fotografía digital</td></tr><tr title="table-row"><td class="td-with-role" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t ; entry_with_role_rowgroup " rowspan="2" align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t"></td></tr><tr title="table-row"><td class="td-with-role" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t ; entry_with_role_rowgroup " rowspan="2" align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">-Frecuencia cardíaca</td></tr><tr title="table-row"><td class="td-with-role" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t ; entry_with_role_rowgroup " rowspan="2" align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t"></td><td class="td-with-role" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t ; entry_with_role_rowgroup " rowspan="2" align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t"></td></tr><tr title="table-row"><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">-Tensión arterial \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t ; entry_with_role_rowhead rowgroup " rowspan="8" align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">Brotzu G, et al.<a class="elsevierStyleCrossRef" href="#bb0080">16</a></td><td class="td-with-role" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t ; entry_with_role_rowgroup " rowspan="8" align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">-Trinov 1 ml</td><td class="td-with-role" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t ; entry_with_role_rowgroup " rowspan="2" align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">-n = 69 (30 H, -29 M)</td><td class="td-with-role" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t ; entry_with_role_rowgroup " rowspan="3" align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">-Fototricograma (Fotofinder-Trichoscan)</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">A los 6 meses: \t\t\t\t\t\t\n \t\t\t\t</td><td class="td-with-role" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t ; entry_with_role_rowgroup " rowspan="8" align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">-Sensación de quemazón leve: n = 1</td></tr><tr title="table-row"><td class="td-with-role" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t ; entry_with_role_rowgroup " rowspan="2" align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">-Incremento anágeno/telógeno</td></tr><tr title="table-row"><td class="td-with-role" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t ; entry_with_role_rowgroup " rowspan="3" align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">-HN: II-IV, L: I-II-6 meses</td></tr><tr title="table-row"><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">-Pull test \t\t\t\t\t\t\n \t\t\t\t</td><td class="td-with-role" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t ; entry_with_role_rowgroup " rowspan="5" align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">-Mejoría pull test y wash test</td></tr><tr title="table-row"><td class="td-with-role" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t ; entry_with_role_rowgroup " rowspan="2" align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">-Microscopia electrónica</td></tr><tr title="table-row"><td class="td-with-role" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t ; entry_with_role_rowgroup " rowspan="3" align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t"></td></tr><tr title="table-row"><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">-Encuesta pacientes \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">-Valoración dermatólogo \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t ; entry_with_role_rowhead rowgroup " rowspan="6" align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">Bussoletti C, et al.<a class="elsevierStyleCrossRef" href="#bb0085">17</a></td><td class="td-with-role" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t ; entry_with_role_rowgroup " rowspan="6" align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">-Champú (B70011) (con cafeína) vs. Champú (B70012)</td><td class="td-with-role" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t ; entry_with_role_rowgroup " rowspan="3" align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">-n = 140 M (70 Ca, 70 Co)</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">-Pull test \t\t\t\t\t\t\n \t\t\t\t</td><td class="td-with-role" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t ; entry_with_role_rowgroup " rowspan="2" align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">-Mejoría pull test</td><td class="td-with-role" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t ; entry_with_role_rowgroup " rowspan="6" align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">-No</td></tr><tr title="table-row"><td class="td-with-role" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t ; entry_with_role_rowgroup " rowspan="5" align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">-Comentarios investigadores y pacientes</td></tr><tr title="table-row"><td class="td-with-role" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t ; entry_with_role_rowgroup " rowspan="3" align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">-Incremento grosor, disminución eritema</td></tr><tr title="table-row"><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">-L: I-III \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t ; entry_with_role_rowgroup " rowspan="2" align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">-6 meses</td></tr><tr title="table-row"><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">-Pacientes satisfechos \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t ; entry_with_role_rowhead rowgroup " rowspan="13" align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">Ghonemy S, et al.<a class="elsevierStyleCrossRef" href="#bb0090">18</a></td><td class="td-with-role" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t ; entry_with_role_rowgroup " rowspan="3" align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">-Minoxidil 10% vs.minoxidil 5% vs. placebo</td><td class="td-with-role" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t ; entry_with_role_rowgroup " rowspan="5" align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">-n = 63 H (n = 27 MT5%, n = 24 MT10%, n = 12 placebo)</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">-Pull test \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">A favor MT5%: \t\t\t\t\t\t\n \t\t\t\t</td><td class="td-with-role" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t ; entry_with_role_rowgroup " rowspan="2" align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">MT 10% vs. MT 5%</td></tr><tr title="table-row"><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">-Fotografías \t\t\t\t\t\t\n \t\t\t\t</td><td class="td-with-role" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t ; entry_with_role_rowgroup " rowspan="6" align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">-Mayor recuento total de pelos terminales en el vértex pero inferior de intermedios en comparación al 10%</td></tr><tr title="table-row"><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">-Tricoscopio \t\t\t\t\t\t\n \t\t\t\t</td><td class="td-with-role" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t ; entry_with_role_rowgroup " rowspan="2" align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">-Dermatitis de contacto 100% vs. 22,2%</td></tr><tr title="table-row"><td class="td-with-role" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t ; entry_with_role_rowgroup " rowspan="10" align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t"></td><td class="td-with-role" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t ; entry_with_role_rowgroup " rowspan="10" align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">-Escala de satisfacción</td></tr><tr title="table-row"><td class="td-with-role" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t ; entry_with_role_rowgroup " rowspan="4" align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">-Erosiones 25% vs. 11,1%</td></tr><tr title="table-row"><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">-HN: III-VII \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t ; entry_with_role_rowgroup " rowspan="7" align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">-36 semanas</td></tr><tr title="table-row"><td class="td-with-role" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t ; entry_with_role_rowgroup " rowspan="2" align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">-Mayor grosor en vértex</td></tr><tr title="table-row"><td class="td-with-role" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t ; entry_with_role_rowgroup " rowspan="3" align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">-Hipertricosis 9 pacientes vs. 6 pacientes</td></tr><tr title="table-row"><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">-Mayor número UF de un cabello y de 3 cabellos en vértex \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t ; entry_with_role_rowgroup " rowspan="3" align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">-Mayor número de UF de 2 cabellos en zona frontal</td></tr><tr title="table-row"><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">-Cefalea 25% vs. 11,1% \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">-Caída cabello al inicio 100% vs 55% \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t ; entry_with_role_rowhead rowgroup " rowspan="6" align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">Katoulis AC, et al.<a class="elsevierStyleCrossRef" href="#bb0095">19</a></td><td class="td-with-role" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t ; entry_with_role_rowgroup " rowspan="6" align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">-CG210® vs. placebo</td><td class="td-with-role" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t ; entry_with_role_rowgroup " rowspan="3" align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">-n = 39 M (26 Ca, 13 Co)</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">-Examen clínico \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">A los 6 meses: \t\t\t\t\t\t\n \t\t\t\t</td><td class="td-with-role" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t ; entry_with_role_rowgroup " rowspan="6" align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">-No</td></tr><tr title="table-row"><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">-Fotografías \t\t\t\t\t\t\n \t\t\t\t</td><td class="td-with-role" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t ; entry_with_role_rowgroup " rowspan="5" align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">-Incremento ratio anágeno/telógeno, mejor DLQI y percepción personal</td></tr><tr title="table-row"><td class="td-with-role" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t ; entry_with_role_rowgroup " rowspan="2" align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">-Evaluación DLQI</td></tr><tr title="table-row"><td class="td-with-role" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t ; entry_with_role_rowgroup " rowspan="2" align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">-L: I-III</td></tr><tr title="table-row"><td class="td-with-role" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t ; entry_with_role_rowgroup " rowspan="2" align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">-Tricograma</td></tr><tr title="table-row"><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">-24 semanas \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t ; entry_with_role_rowhead rowgroup " rowspan="3" align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">Rossi A, et al.<a class="elsevierStyleCrossRef" href="#bb0100">20</a></td><td class="td-with-role" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t ; entry_with_role_rowgroup " rowspan="3" align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">-Cetirizina 1% vs. placebo</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">-n = 85 (67 Ca, 18 Co) \t\t\t\t\t\t\n \t\t\t\t</td><td class="td-with-role" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t ; entry_with_role_rowgroup " rowspan="2" align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">-Fotografías (Trichoscon Dermoscope Fotofinder®)</td><td class="td-with-role" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t ; entry_with_role_rowgroup " rowspan="3" align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">-X</td><td class="td-with-role" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t ; entry_with_role_rowgroup " rowspan="3" align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">-No</td></tr><tr title="table-row"><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">-X \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">-6 meses \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">-Evaluación por dermatólogos \t\t\t\t\t\t\n \t\t\t\t</td></tr></tbody></table> """ ] "imagenFichero" => array:1 [ 0 => "xTab2618531.png" ] ] ] ] "descripcion" => array:1 [ "es" => "Artículos seleccionados de tratamiento tópico de la alopecia androgénica" ] ] 2 => array:8 [ "identificador" => "t0015" "etiqueta" => "Tabla 3" "tipo" => "MULTIMEDIATABLA" "mostrarFloat" => true "mostrarDisplay" => false "detalles" => array:1 [ 0 => array:3 [ "identificador" => "al0015" "detalle" => "Tabla " "rol" => "short" ] ] "tabla" => array:2 [ "leyenda" => "A-PRP: plasma rico en plaquetas autógeno no activado; Ca: casos; Co: controles; H: hombres; HN: Hamilton-Norwood; L: Ludwig; M: mujeres; MT: minoxidil tópico; N: número de pacientes; PRP: plasma rico en plaquetas; X: no recogido." "tablatextoimagen" => array:1 [ 0 => array:2 [ "tabla" => array:1 [ 0 => """ <table border="0" frame="\n \t\t\t\t\tvoid\n \t\t\t\t" class=""><thead title="thead"><tr title="table-row"><th class="td" title="\n \t\t\t\t\ttable-head\n \t\t\t\t " align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t" scope="col" style="border-bottom: 2px solid black">Autor \t\t\t\t\t\t\n \t\t\t\t\t\t</th><th class="td" title="\n \t\t\t\t\ttable-head\n \t\t\t\t " align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t" scope="col" style="border-bottom: 2px solid black">Modelo PRP/intervención \t\t\t\t\t\t\n \t\t\t\t\t\t</th><th class="td" title="\n \t\t\t\t\ttable-head\n \t\t\t\t " align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t" scope="col" style="border-bottom: 2px solid black">Pacientes/escalas/ seguimiento \t\t\t\t\t\t\n \t\t\t\t\t\t</th><th class="td" title="\n \t\t\t\t\ttable-head\n \t\t\t\t " align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t" scope="col" style="border-bottom: 2px solid black">Evaluación \t\t\t\t\t\t\n \t\t\t\t\t\t</th><th class="td" title="\n \t\t\t\t\ttable-head\n \t\t\t\t " align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t" scope="col" style="border-bottom: 2px solid black">P < 0.05 \t\t\t\t\t\t\n \t\t\t\t\t\t</th><th class="td" title="\n \t\t\t\t\ttable-head\n \t\t\t\t " align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t" scope="col" style="border-bottom: 2px solid black">Efectos secundarios n (%) \t\t\t\t\t\t\n \t\t\t\t\t\t</th></tr></thead><tbody title="tbody"><tr title="table-row"><td class="td-with-role" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t ; entry_with_role_rowhead rowgroup " rowspan="4" align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">Rodrigues B, et al.<a class="elsevierStyleCrossRef" href="#bb0105">21</a></td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">-X \t\t\t\t\t\t\n \t\t\t\t</td><td class="td-with-role" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t ; entry_with_role_rowgroup " rowspan="2" align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">-n = 26 H (15 Ca, 11 Co)</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">-TrichoScan \t\t\t\t\t\t\n \t\t\t\t</td><td class="td-with-role" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t ; entry_with_role_rowgroup " rowspan="4" align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">-Incremento en el recuento y densidad de cabellos y en el % de pelos en anágeno a los 3 meses de la última inyección</td><td class="td-with-role" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t ; entry_with_role_rowgroup " rowspan="4" align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">-X</td></tr><tr title="table-row"><td class="td-with-role" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t ; entry_with_role_rowgroup " rowspan="3" align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">-PRP vs. suero</td><td class="td-with-role" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t ; entry_with_role_rowgroup " rowspan="3" align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">-Siemens Advia2120 I (técnica Luminex)</td></tr><tr title="table-row"><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">-HN III vértex \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">-3 meses \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t ; entry_with_role_rowhead rowgroup " rowspan="8" align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">Butt G, et al.<a class="elsevierStyleCrossRef" href="#bb0110">22</a></td><td class="td-with-role" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t ; entry_with_role_rowgroup " rowspan="3" align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">-Tray Life Tube Gel</td><td class="td-with-role" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t ; entry_with_role_rowgroup " rowspan="4" align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">-n = 30 (20 H, 10 M)</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">-Fotografías \t\t\t\t\t\t\n \t\t\t\t</td><td class="td-with-role" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t ; entry_with_role_rowgroup " rowspan="2" align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">A los 6 meses:</td><td class="td-with-role" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t ; entry_with_role_rowgroup " rowspan="8" align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">-X</td></tr><tr title="table-row"><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">-Pull test \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t ; entry_with_role_rowgroup " rowspan="3" align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">-Tricoscopic Photomicrographs</td><td class="td-with-role" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t ; entry_with_role_rowgroup " rowspan="5" align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">-Mejoría en el pull test, evaluación médica y satisfacción del paciente</td></tr><tr title="table-row"><td class="td-with-role" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t ; entry_with_role_rowgroup " rowspan="5" align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">-PRP</td></tr><tr title="table-row"><td class="td-with-role" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t ; entry_with_role_rowgroup " rowspan="2" align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">-HN: II, IV, VI, L: I-III</td></tr><tr title="table-row"><td class="td-with-role" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t ; entry_with_role_rowgroup " rowspan="3" align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">-Evaluación médica y escala de satisfacción del paciente</td></tr><tr title="table-row"><td class="td-with-role" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t ; entry_with_role_rowgroup " rowspan="2" align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">-6 meses</td></tr><tr title="table-row"><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">-Aumento de la densidad capilar \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t ; entry_with_role_rowhead rowgroup " rowspan="5" align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">Schiavone G, et al.<a class="elsevierStyleCrossRef" href="#bb0115">23</a></td><td class="td-with-role" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t ; entry_with_role_rowgroup " rowspan="2" align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">-GLO PRP blood separation kit</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">-n = 168 (102 H, 66 M) \t\t\t\t\t\t\n \t\t\t\t</td><td class="td-with-role" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t ; entry_with_role_rowgroup " rowspan="5" align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">-Fotografías evaluadas por expertos</td><td class="td-with-role" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t ; entry_with_role_rowgroup " rowspan="5" align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">-Mejoría clínica con respecto al grupo control</td><td class="td-with-role" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t ; entry_with_role_rowgroup " rowspan="5" align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">-Hematomas</td></tr><tr title="table-row"><td class="td-with-role" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t ; entry_with_role_rowgroup " rowspan="2" align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">(139 Ca, 29 Co)</td></tr><tr title="table-row"><td class="td-with-role" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t ; entry_with_role_rowgroup " rowspan="3" align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">-iL-PRF vs. nada</td></tr><tr title="table-row"><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">-HN: II-V, L: I-II \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">-X \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t ; entry_with_role_rowhead rowgroup " rowspan="12" align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">Hausauer A, et al.<a class="elsevierStyleCrossRef" href="#bb0120">24</a></td><td class="td-with-role" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t ; entry_with_role_rowgroup " rowspan="2" align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">-Eclipse PRP kit</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">-n = 39 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">-Folioscopio \t\t\t\t\t\t\n \t\t\t\t</td><td class="td-with-role" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t ; entry_with_role_rowgroup " rowspan="5" align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">A los 6 meses en ambos grupos:</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">-n = 39 \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t ; entry_with_role_rowgroup " rowspan="2" align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">PRP 1: 20 (17 H, 3 M)</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">-Fotografías \t\t\t\t\t\t\n \t\t\t\t</td><td class="td-with-role" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t ; entry_with_role_rowgroup " rowspan="3" align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">-Dolor/molestias:</td></tr><tr title="table-row"><td class="td-with-role" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t ; entry_with_role_rowgroup " rowspan="10" align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">-PRP 1 vs. PRP 2</td><td class="td-with-role" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t ; entry_with_role_rowgroup " rowspan="10" align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">-Encuestas de satisfacción</td></tr><tr title="table-row"><td class="td-with-role" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t ; entry_with_role_rowgroup " rowspan="6" align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">PRP 2: 19 (12 H, 7 M)</td></tr><tr title="table-row"><td class="td-with-role" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t ; entry_with_role_rowgroup " rowspan="2" align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">n = 12 (30,7%)</td></tr><tr title="table-row"><td class="td-with-role" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t ; entry_with_role_rowgroup " rowspan="5" align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">-Mejoría en el recuento capilar (más rápido y clínicamente relevante en el grupo 1)</td></tr><tr title="table-row"><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">-Cefalea: n = 5 (12,8%), \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">-Picor: n = 8 \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t ; entry_with_role_rowgroup " rowspan="4" align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">(15,4%)</td></tr><tr title="table-row"><td class="td-with-role" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t ; entry_with_role_rowgroup " rowspan="2" align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">-HN: II-V, L: I2-II1</td></tr><tr title="table-row"><td class="td-with-role" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t ; entry_with_role_rowgroup " rowspan="2" align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">-Mejoría en el calibre</td></tr><tr title="table-row"><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">-6 meses \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t ; entry_with_role_rowhead rowgroup " rowspan="4" align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">Gentile P, et al.<a class="elsevierStyleCrossRef" href="#bb0125">25</a></td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">-X \t\t\t\t\t\t\n \t\t\t\t</td><td class="td-with-role" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t ; entry_with_role_rowgroup " rowspan="2" align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">-n = 23 (18 H, 5 M)</td><td class="td-with-role" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t ; entry_with_role_rowgroup " rowspan="4" align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">-Tricoscopio</td><td class="td-with-role" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t ; entry_with_role_rowgroup " rowspan="4" align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">-X</td><td class="td-with-role" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t ; entry_with_role_rowgroup " rowspan="4" align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">-X</td></tr><tr title="table-row"><td class="td-with-role" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t ; entry_with_role_rowgroup " rowspan="3" align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">-A-PRP vs. suero</td></tr><tr title="table-row"><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">-HN: II-V,L: I-II \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">-5 meses \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t ; entry_with_role_rowhead rowgroup " rowspan="6" align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">Dicle Ö, et al.<a class="elsevierStyleCrossRef" href="#bb0130">26</a></td><td class="td-with-role" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t ; entry_with_role_rowgroup " rowspan="2" align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">-Genesis PRP kit</td><td class="td-with-role" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t ; entry_with_role_rowgroup " rowspan="4" align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">-n = 25 H (10 Ca, 15 Co)</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">-TrichoScan \t\t\t\t\t\t\n \t\t\t\t</td><td class="td-with-role" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t ; entry_with_role_rowgroup " rowspan="6" align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">-Recuento capilar total superior en el grupo placebo cuando se comparó M4 vs M9 y M0 vs M9</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">-Dolor local \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t ; entry_with_role_rowgroup " rowspan="2" align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">-2 dermatólogos</td><td class="td-with-role" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t ; entry_with_role_rowgroup " rowspan="5" align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">-Edema transitorio</td></tr><tr title="table-row"><td class="td-with-role" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t ; entry_with_role_rowgroup " rowspan="4" align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">-PRP vs. placebo</td></tr><tr title="table-row"><td class="td-with-role" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t ; entry_with_role_rowgroup " rowspan="3" align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">-Recuento manual con el software ImageJ</td></tr><tr title="table-row"><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">-HN: IIIv-V \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">-4 meses \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t ; entry_with_role_rowhead rowgroup " rowspan="8" align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">Verma K, et al.<a class="elsevierStyleCrossRef" href="#bb0135">27</a></td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">-X \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">-n = 30 H \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">-Fotografías \t\t\t\t\t\t\n \t\t\t\t</td><td class="td-with-role" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t ; entry_with_role_rowgroup " rowspan="4" align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">A los 6 meses a favor del PRP:</td><td class="td-with-role" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t ; entry_with_role_rowgroup " rowspan="8" align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">-Dolor: 4 pacientes del grupo del PRP dejan el estudio por el dolor provocado por las inyecciones</td></tr><tr title="table-row"><td class="td-with-role" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t ; entry_with_role_rowgroup " rowspan="7" align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">-PRP vs. MT 5%</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">-PRP: 16 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">-Pull Test \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">-MT5%: 14 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td-with-role" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t ; entry_with_role_rowgroup " rowspan="3" align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">-Cuestionario de crecimiento capilar</td></tr><tr title="table-row"><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">-HN: II-V \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t ; entry_with_role_rowgroup " rowspan="4" align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">-6 meses</td><td class="td-with-role" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t ; entry_with_role_rowgroup " rowspan="3" align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">-Mejoría en 2 preguntas del cuestionario de crecimiento capilar</td></tr><tr title="table-row"><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">-Encuesta de satisfacción \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t ; entry_with_role_rowgroup " rowspan="2" align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">-Recuento plaquetario en el PRP</td></tr><tr title="table-row"><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">-Mejores resultados en la encuesta de satisfacción \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t ; entry_with_role_rowhead rowgroup " rowspan="8" align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">Qu Q, et al.<a class="elsevierStyleCrossRef" href="#bb0140">28</a></td><td class="td-with-role" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t ; entry_with_role_rowgroup " rowspan="3" align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">-Tricell kit</td><td class="td-with-role" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t ; entry_with_role_rowgroup " rowspan="4" align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">-n = 93 (51 H, 42 M)</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">-Pull test \t\t\t\t\t\t\n \t\t\t\t</td><td class="td-with-role" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t ; entry_with_role_rowgroup " rowspan="2" align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">A los 6 meses:</td><td class="td-with-role" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t ; entry_with_role_rowgroup " rowspan="2" align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">-n = 53 (30 H, 23 M)</td></tr><tr title="table-row"><td class="td-with-role" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t ; entry_with_role_rowgroup " rowspan="3" align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">-Fototricograma</td></tr><tr title="table-row"><td class="td-with-role" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t ; entry_with_role_rowgroup " rowspan="3" align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">-Incremento de grosor y densidad</td><td class="td-with-role" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t ; entry_with_role_rowgroup " rowspan="4" align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">-Dolor leve, picor leve: n = 2 (H)</td></tr><tr title="table-row"><td class="td-with-role" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t ; entry_with_role_rowgroup " rowspan="5" align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">-PRP</td></tr><tr title="table-row"><td class="td-with-role" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t ; entry_with_role_rowgroup " rowspan="3" align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">-HN: II-V, L: I-III</td><td class="td-with-role" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t ; entry_with_role_rowgroup " rowspan="2" align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">-Fotografías</td></tr><tr title="table-row"><td class="td-with-role" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t ; entry_with_role_rowgroup " rowspan="3" align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">-Mejoría en la inflamación del scalp, la secreción grasa y el hair-pull test</td></tr><tr title="table-row"><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">-Cuestionarios de satisfacción \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">-Cefalea: n = 1 (M) \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">-6 meses \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">-TrichoScan \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">-Sensación de lagrimeo: n = 1 (M) \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t ; entry_with_role_rowhead rowgroup " rowspan="4" align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">Starace M, et al.<a class="elsevierStyleCrossRef" href="#bb0145">29</a></td><td class="td-with-role" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t ; entry_with_role_rowgroup " rowspan="3" align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">-My Cells ®system</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">-n = 10 M \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">-Pull test \t\t\t\t\t\t\n \t\t\t\t</td><td class="td-with-role" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t ; entry_with_role_rowgroup " rowspan="2" align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">A las 12 y 24 semanas:</td><td class="td-with-role" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t ; entry_with_role_rowgroup " rowspan="4" align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">-No efectos adversos severos registrados</td></tr><tr title="table-row"><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">-L: I-III \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">-Fotografías \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t ; entry_with_role_rowgroup " rowspan="2" align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">-24 semanas</td><td class="td-with-role" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t ; entry_with_role_rowgroup " rowspan="2" align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">-Trichoscan (FotoFinder dermatoscope®)</td><td class="td-with-role" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t ; entry_with_role_rowgroup " rowspan="2" align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">-Incremento del diámetro en la zona frontal</td></tr><tr title="table-row"><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">-PRP \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t ; entry_with_role_rowhead rowgroup " rowspan="4" align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">Bayat M, et al.<a class="elsevierStyleCrossRef" href="#bb0150">30</a></td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">-X \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">-n = 19 H \t\t\t\t\t\t\n \t\t\t\t</td><td class="td-with-role" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t ; entry_with_role_rowgroup " rowspan="3" align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">-Fotografía digital y dermatoscópica</td><td class="td-with-role" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t ; entry_with_role_rowgroup " rowspan="4" align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">-Incremento del grosor capilar después de la primera inyección en comparación con el resto</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">-Dolor leve y localizado \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t ; entry_with_role_rowgroup " rowspan="3" align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">-PRP</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">-HN: IIIv-V \t\t\t\t\t\t\n \t\t\t\t</td><td class="td-with-role" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t ; entry_with_role_rowgroup " rowspan="3" align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">-Sangrado leve</td></tr><tr title="table-row"><td class="td-with-role" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t ; entry_with_role_rowgroup " rowspan="2" align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">-5 meses</td></tr><tr title="table-row"><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">-Evaluación por dermatólogos \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t ; entry_with_role_rowhead rowgroup " rowspan="6" align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">Jha AK, et al.<a class="elsevierStyleCrossRef" href="#bb0155">31</a></td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">-X \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">-n = 93 H \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">-Fotografías \t\t\t\t\t\t\n \t\t\t\t</td><td class="td-with-role" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t ; entry_with_role_rowgroup " rowspan="2" align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">A los 3 meses:</td><td class="td-with-role" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t ; entry_with_role_rowgroup " rowspan="6" align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">-Dolor transitorio en B) y C)</td></tr><tr title="table-row"><td class="td-with-role" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t ; entry_with_role_rowgroup " rowspan="2" align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">-A) MT5% vs.</td><td class="td-with-role" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t ; entry_with_role_rowgroup " rowspan="3" align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">-A (n = 31, B n= 31, C n= 31)</td><td class="td-with-role" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t ; entry_with_role_rowgroup " rowspan="2" align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">-Dermatoscopio</td></tr><tr title="table-row"><td class="td-with-role" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t ; entry_with_role_rowgroup " rowspan="4" align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">-Mejores resultados en C) en: hair pull test, ratio terminal/velloso y escala de satisfacción</td></tr><tr title="table-row"><td class="td-with-role" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t ; entry_with_role_rowgroup " rowspan="2" align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">B) MT5% + PRP vs.</td><td class="td-with-role" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t ; entry_with_role_rowgroup " rowspan="2" align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">-Hair pull test</td></tr><tr title="table-row"><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">-HN: I-V \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">C) PRP + microneedling \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">-3 meses \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">-Escala de satisfacción \t\t\t\t\t\t\n \t\t\t\t</td></tr></tbody></table> """ ] "imagenFichero" => array:1 [ 0 => "xTab2618527.png" ] ] ] ] "descripcion" => array:1 [ "es" => "Artículos seleccionados de tratamiento de la alopecia androgénica con plasma rico en plaquetas" ] ] 3 => array:8 [ "identificador" => "t0020" "etiqueta" => "Tabla 4" "tipo" => "MULTIMEDIATABLA" "mostrarFloat" => true "mostrarDisplay" => false "detalles" => array:1 [ 0 => array:3 [ "identificador" => "al0020" "detalle" => "Tabla " "rol" => "short" ] ] "tabla" => array:2 [ "leyenda" => "A-PRP: plasma rico en plaquetas autógeno no activado; BMMC: células mononucleares derivadas de la médula ósea; FSC: células madre foliculares; H: hombres; HF-MSC: microinjertos que contienen células madre mesenquimales del folículo humano; HN: Hamilton-Norwood; L: Ludwig; LLLT: láser de baja potencia; M: mujeres; N: número de pacientes; X: no recogido." "tablatextoimagen" => array:1 [ 0 => array:2 [ "tabla" => array:1 [ 0 => """ <table border="0" frame="\n \t\t\t\t\tvoid\n \t\t\t\t" class=""><thead title="thead"><tr title="table-row"><th class="td" title="\n \t\t\t\t\ttable-head\n \t\t\t\t " align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t" scope="col" style="border-bottom: 2px solid black">Autor \t\t\t\t\t\t\n \t\t\t\t\t\t</th><th class="td" title="\n \t\t\t\t\ttable-head\n \t\t\t\t " align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t" scope="col" style="border-bottom: 2px solid black">Intervención \t\t\t\t\t\t\n \t\t\t\t\t\t</th><th class="td" title="\n \t\t\t\t\ttable-head\n \t\t\t\t " align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t" scope="col" style="border-bottom: 2px solid black">Pacientes/escalas/ seguimiento \t\t\t\t\t\t\n \t\t\t\t\t\t</th><th class="td" title="\n \t\t\t\t\ttable-head\n \t\t\t\t " align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t" scope="col" style="border-bottom: 2px solid black">Evaluación \t\t\t\t\t\t\n \t\t\t\t\t\t</th><th class="td" title="\n \t\t\t\t\ttable-head\n \t\t\t\t " align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t" scope="col" style="border-bottom: 2px solid black">P < 0,05 \t\t\t\t\t\t\n \t\t\t\t\t\t</th><th class="td" title="\n \t\t\t\t\ttable-head\n \t\t\t\t " align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t" scope="col" style="border-bottom: 2px solid black">Efectos secundarios (n/%) \t\t\t\t\t\t\n \t\t\t\t\t\t</th></tr></thead><tbody title="tbody"><tr title="table-row"><td class="td-with-role" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t ; entry_with_role_rowhead rowgroup " rowspan="10" align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">Elmaadawi IH, et al.<a class="elsevierStyleCrossRef" href="#bb0160">32</a></td><td class="td-with-role" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t ; entry_with_role_rowgroup " rowspan="10" align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">-BMMC vs. FSC</td><td class="td-with-role" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t ; entry_with_role_rowgroup " rowspan="4" align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">-n = 20 (10 = BMMC [3 H, 7 M] 10 FSC [5 H, 5 M])</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">-Fotografías \t\t\t\t\t\t\n \t\t\t\t</td><td class="td-with-role" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t ; entry_with_role_rowgroup " rowspan="2" align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">A los 6 meses:</td><td class="td-with-role" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t ; entry_with_role_rowgroup " rowspan="6" align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">-Fatiga inducida por el factor estimulante de colonias de granulocitos</td></tr><tr title="table-row"><td class="td-with-role" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t ; entry_with_role_rowgroup " rowspan="2" align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">-Estudio histopatológico</td></tr><tr title="table-row"><td class="td-with-role" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t ; entry_with_role_rowgroup " rowspan="8" align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">-Incremento del diámetro capilar y de la densidad por cm2 en ambos grupos sin diferencias significativas entre ellos</td></tr><tr title="table-row"><td class="td-with-role" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t ; entry_with_role_rowgroup " rowspan="2" align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">-Encuesta de satisfacción</td></tr><tr title="table-row"><td class="td-with-role" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t ; entry_with_role_rowgroup " rowspan="3" align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">-X</td></tr><tr title="table-row"><td class="td-with-role" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t ; entry_with_role_rowgroup " rowspan="5" align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">-Dermatoscopia</td></tr><tr title="table-row"><td class="td-with-role" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t ; entry_with_role_rowgroup " rowspan="2" align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">-Síntomas gripales</td></tr><tr title="table-row"><td class="td-with-role" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t ; entry_with_role_rowgroup " rowspan="3" align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">-6 meses</td></tr><tr title="table-row"><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">-Dolor óseo y hematoma \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">-Dermatitis del scalp en FSC \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t ; entry_with_role_rowhead rowgroup " rowspan="7" align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">Gentile P, et al.<a class="elsevierStyleCrossRef" href="#bb0165">33</a></td><td class="td-with-role" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t ; entry_with_role_rowgroup " rowspan="5" align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">-A-PRP + LLLT vs. - HF-MSC + LLLT vs. placebo</td><td class="td-with-role" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t ; entry_with_role_rowgroup " rowspan="2" align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">-n = 78 (57 A-PRP, 21 HF-MSC), 56 H, 22 M</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">-Fotografías \t\t\t\t\t\t\n \t\t\t\t</td><td class="td-with-role" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t ; entry_with_role_rowgroup " rowspan="3" align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">A las 12 semanas tras el último tratamiento:</td><td class="td-with-role" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t ; entry_with_role_rowgroup " rowspan="7" align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">-X</td></tr><tr title="table-row"><td class="td-with-role" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t ; entry_with_role_rowgroup " rowspan="6" align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">-Evaluación médica y de los pacientes</td></tr><tr title="table-row"><td class="td-with-role" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t ; entry_with_role_rowgroup " rowspan="4" align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">-HN: II-V, L: I-II</td></tr><tr title="table-row"><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">-Incremento del recuento y de la densidad \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t ; entry_with_role_rowgroup " rowspan="3" align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">-Incremento en la densidad capilar</td></tr><tr title="table-row"><td class="td-with-role" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t ; entry_with_role_rowgroup " rowspan="2" align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t"></td></tr><tr title="table-row"><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">-221 días \t\t\t\t\t\t\n \t\t\t\t</td></tr></tbody></table> """ ] "imagenFichero" => array:1 [ 0 => "xTab2618532.png" ] ] ] ] "descripcion" => array:1 [ "es" => "Artículos seleccionados de tratamiento con células madre de la alopecia androgénica" ] ] 4 => array:8 [ "identificador" => "t0025" "etiqueta" => "Tabla 5" "tipo" => "MULTIMEDIATABLA" "mostrarFloat" => true "mostrarDisplay" => false "detalles" => array:1 [ 0 => array:3 [ "identificador" => "al0025" "detalle" => "Tabla " "rol" => "short" ] ] "tabla" => array:2 [ "leyenda" => "Ca: casos; Co: controles; H: hombres; HN: Hamilton-Norwood; L: Ludwig; LF: láser fraccionado; LLLT: láser de baja potencia; M: mujeres; N: número de pacientes; RF: radiofrecuencia fraccionada; X: no recogido." "tablatextoimagen" => array:1 [ 0 => array:2 [ "tabla" => array:1 [ 0 => """ <table border="0" frame="\n \t\t\t\t\tvoid\n \t\t\t\t" class=""><thead title="thead"><tr title="table-row"><th class="td" title="\n \t\t\t\t\ttable-head\n \t\t\t\t " align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t" scope="col" style="border-bottom: 2px solid black">Autor \t\t\t\t\t\t\n \t\t\t\t\t\t</th><th class="td" title="\n \t\t\t\t\ttable-head\n \t\t\t\t " align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t" scope="col" style="border-bottom: 2px solid black">Aparatología \t\t\t\t\t\t\n \t\t\t\t\t\t</th><th class="td" title="\n \t\t\t\t\ttable-head\n \t\t\t\t " align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t" scope="col" style="border-bottom: 2px solid black">Pacientes/ escalas/ Seguimiento \t\t\t\t\t\t\n \t\t\t\t\t\t</th><th class="td" title="\n \t\t\t\t\ttable-head\n \t\t\t\t " align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t" scope="col" style="border-bottom: 2px solid black">Evaluación \t\t\t\t\t\t\n \t\t\t\t\t\t</th><th class="td" title="\n \t\t\t\t\ttable-head\n \t\t\t\t " align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t" scope="col" style="border-bottom: 2px solid black">P < 0.05 \t\t\t\t\t\t\n \t\t\t\t\t\t</th><th class="td" title="\n \t\t\t\t\ttable-head\n \t\t\t\t " align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t" scope="col" style="border-bottom: 2px solid black">Efectos adversos \t\t\t\t\t\t\n \t\t\t\t\t\t</th></tr></thead><tbody title="tbody"><tr title="table-row"><td class="td-with-role" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t ; entry_with_role_rowhead rowgroup " rowspan="6" align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">Suchonwanit P, et al.<a class="elsevierStyleCrossRef" href="#bb0170">34</a></td><td class="td-with-role" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t ; entry_with_role_rowgroup " rowspan="6" align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">-RAMACAP (LLLT)</td><td class="td-with-role" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t ; entry_with_role_rowgroup " rowspan="2" align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">-n = 36 (19 Ca [10 H, 9 M], 17Co [9 H, 8 M])</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">-Fotografía con tricoscopio (Follioscope®) \t\t\t\t\t\t\n \t\t\t\t</td><td class="td-with-role" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t ; entry_with_role_rowgroup " rowspan="4" align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">A las 24 semanas:</td><td class="td-with-role" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t ; entry_with_role_rowgroup " rowspan="5" align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">-Aumento de la caída capilar (n = 1)</td></tr><tr title="table-row"><td class="td-with-role" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t ; entry_with_role_rowgroup " rowspan="5" align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">-Fotografías valoradas por dermatólogos</td></tr><tr title="table-row"><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">-HN: IIIv, IV, V, L: I-III \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t ; entry_with_role_rowgroup " rowspan="3" align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">-24 semanas</td></tr><tr title="table-row"><td class="td-with-role" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t ; entry_with_role_rowgroup " rowspan="2" align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">-Incremento en la densidad y en el diámetro, mejor encuesta de satisfacción y valoración fotográfica de los investigadores</td></tr><tr title="table-row"><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">-Picor leve (n = 3)(2 Ca, 1 Co) \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t ; entry_with_role_rowhead rowgroup " rowspan="8" align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">Doghaim NN, et al.<a class="elsevierStyleCrossRef" href="#bb0175">35</a></td><td class="td-with-role" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t ; entry_with_role_rowgroup " rowspan="8" align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">-Carboxiterapia vs. placebo</td><td class="td-with-role" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t ; entry_with_role_rowgroup " rowspan="6" align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">-n = 40 H (20 Ca, 20 Co)</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">-Fotografías \t\t\t\t\t\t\n \t\t\t\t</td><td class="td-with-role" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t ; entry_with_role_rowgroup " rowspan="5" align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">A las 22 semanas:</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">-Dolor leve \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">-Dermatoscopia \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">-Sensación de quemazón \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t ; entry_with_role_rowgroup " rowspan="6" align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">-Autoevaluación</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">-Eritema \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">-Edema \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t ; entry_with_role_rowgroup " rowspan="4" align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">-Cefalea (n = 8)</td></tr><tr title="table-row"><td class="td-with-role" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t ; entry_with_role_rowgroup " rowspan="3" align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">Mejoría clínica de los casos, pero regresión tras el cese del tratamiento</td></tr><tr title="table-row"><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">-HN: I-V \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">-22 semanas \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t ; entry_with_role_rowhead rowgroup " rowspan="11" align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">Meephansan J, et al.<a class="elsevierStyleCrossRef" href="#bb0180">36</a></td><td class="td-with-role" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t ; entry_with_role_rowgroup " rowspan="11" align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">-Er:Glass (LF)</td><td class="td-with-role" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t ; entry_with_role_rowgroup " rowspan="4" align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">-n = 23 (16 H, 7 M)</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">-Fotografías \t\t\t\t\t\t\n \t\t\t\t</td><td class="td-with-role" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t ; entry_with_role_rowgroup " rowspan="2" align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">A los 6 meses:</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">-n = 23 \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t ; entry_with_role_rowgroup " rowspan="2" align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">-Punch</td><td class="td-with-role" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t ; entry_with_role_rowgroup " rowspan="4" align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">-Dolor y picor tolerable durante la primera sesión</td></tr><tr title="table-row"><td class="td-with-role" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t ; entry_with_role_rowgroup " rowspan="4" align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">-Incremento en la densidad y el diámetro</td></tr><tr title="table-row"><td class="td-with-role" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t ; entry_with_role_rowgroup " rowspan="2" align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">-Biopsia scalp</td></tr><tr title="table-row"><td class="td-with-role" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t ; entry_with_role_rowgroup " rowspan="3" align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">-HN: III, IIIv, IV, L: II</td></tr><tr title="table-row"><td class="td-with-role" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t ; entry_with_role_rowgroup " rowspan="3" align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">-Valoración por un dermatólogo</td><td class="td-with-role" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t ; entry_with_role_rowgroup " rowspan="6" align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">-Eritema en algunos pacientes</td></tr><tr title="table-row"><td class="td-with-role" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t ; entry_with_role_rowgroup " rowspan="3" align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">-Incremento de los pelos terminales (a los 5 meses) y no de los vellosos</td></tr><tr title="table-row"><td class="td-with-role" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t ; entry_with_role_rowgroup " rowspan="4" align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">-6 meses</td></tr><tr title="table-row"><td class="td-with-role" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t ; entry_with_role_rowgroup " rowspan="3" align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">-Encuestas de satisfacción</td></tr><tr title="table-row"><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">-Reducción del ratio velloso / no vello \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">-Aumento del diámetro \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t ; entry_with_role_rowhead rowgroup " rowspan="7" align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">Faghihi G, et al.<a class="elsevierStyleCrossRef" href="#bb0185">37</a></td><td class="td-with-role" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t ; entry_with_role_rowgroup " rowspan="7" align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">-LLLT + MT5% vs. MT5%</td><td class="td-with-role" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t ; entry_with_role_rowgroup " rowspan="3" align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">-n = 45 (23 Ca, 22 Co)</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">-Tricograma \t\t\t\t\t\t\n \t\t\t\t</td><td class="td-with-role" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t ; entry_with_role_rowgroup " rowspan="5" align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">A los 12 meses</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">-Cefalea \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t ; entry_with_role_rowgroup " rowspan="6" align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">-Encuesta satisfaccion</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">-Picor \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t ; entry_with_role_rowgroup " rowspan="2" align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">-Quemazón</td></tr><tr title="table-row"><td class="td-with-role" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t ; entry_with_role_rowgroup " rowspan="2" align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">-HN: III-VI, L: II-III</td></tr><tr title="table-row"><td class="td-with-role" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t ; entry_with_role_rowgroup " rowspan="3" align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">-Eritema (más prevalente en controles)</td></tr><tr title="table-row"><td class="td-with-role" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t ; entry_with_role_rowgroup " rowspan="2" align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">-12 meses</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">-Ca vs. Co: \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">Mayor recuperación del grado de alopecia, grado de satisfacción, recuento y diámetro capilar \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t ; entry_with_role_rowhead rowgroup " rowspan="5" align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">Verner I, et al.<a class="elsevierStyleCrossRef" href="#bb0190">38</a></td><td class="td-with-role" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t ; entry_with_role_rowgroup " rowspan="5" align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">-Hairlux ® (RF)</td><td class="td-with-role" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t ; entry_with_role_rowgroup " rowspan="2" align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">-n = 25 (7 H, 18 M)</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">-Fotografías \t\t\t\t\t\t\n \t\t\t\t</td><td class="td-with-role" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t ; entry_with_role_rowgroup " rowspan="5" align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">-X</td><td class="td-with-role" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t ; entry_with_role_rowgroup " rowspan="5" align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">-Leve hormigueo y sensibilidad hasta 24 h postratamiento</td></tr><tr title="table-row"><td class="td-with-role" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t ; entry_with_role_rowgroup " rowspan="3" align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">-Dermatoscopia (10 pacientes)</td></tr><tr title="table-row"><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">-X \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t ; entry_with_role_rowgroup " rowspan="2" align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">-7 meses</td></tr><tr title="table-row"><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">-Encuestas de satisfacción \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t ; entry_with_role_rowhead rowgroup " rowspan="11" align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">Suchonwanit P, et al.<a class="elsevierStyleCrossRef" href="#bb0195">39</a></td><td class="td-with-role" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t ; entry_with_role_rowgroup " rowspan="11" align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">-Er:Glass (LF) + MT5% vs. MT 5%</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">-n = 29 H \t\t\t\t\t\t\n \t\t\t\t</td><td class="td-with-role" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t ; entry_with_role_rowgroup " rowspan="5" align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">-Fotografía con tricoscopio (Follioscope®)</td><td class="td-with-role" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t ; entry_with_role_rowgroup " rowspan="3" align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">Ca vs. Co a las 24 semanas:</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">Ca: \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">-HN: III-VI \t\t\t\t\t\t\n \t\t\t\t</td><td class="td-with-role" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t ; entry_with_role_rowgroup " rowspan="3" align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">-Dolor + quemazón (n = 9)</td></tr><tr title="table-row"><td class="td-with-role" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t ; entry_with_role_rowgroup " rowspan="9" align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">-24 semanas</td></tr><tr title="table-row"><td class="td-with-role" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t ; entry_with_role_rowgroup " rowspan="8" align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">-Mejoría de la densidad, el diámetro, la valoración por dermatólogos y la satisfacción de los participantes</td></tr><tr title="table-row"><td class="td-with-role" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t ; entry_with_role_rowgroup " rowspan="2" align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">-Eritema (n = 6)</td></tr><tr title="table-row"><td class="td-with-role" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t ; entry_with_role_rowgroup " rowspan="2" align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">-Fotografías</td></tr><tr title="table-row"><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">-Picor (n = 4) \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t ; entry_with_role_rowgroup " rowspan="4" align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">-Valoración por dermatólogos</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">-Descamación (n = 2) \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">Co: \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">-Picor (n = 5) \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">-Descamación (n = 3) \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t ; entry_with_role_rowhead rowgroup " rowspan="9" align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">Starace M, et al.<a class="elsevierStyleCrossRef" href="#bb0200">40</a></td><td class="td-with-role" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t ; entry_with_role_rowgroup " rowspan="9" align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">-Microneedling</td><td class="td-with-role" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t ; entry_with_role_rowgroup " rowspan="4" align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">-n = 43 (14 H, 29 M)</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">-Fotografías \t\t\t\t\t\t\n \t\t\t\t</td><td class="td-with-role" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t ; entry_with_role_rowgroup " rowspan="9" align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">-X</td><td class="td-with-role" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t ; entry_with_role_rowgroup " rowspan="2" align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">-Dolor bien tolerado</td></tr><tr title="table-row"><td class="td-with-role" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t ; entry_with_role_rowgroup " rowspan="2" align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">-Tricoscopia</td></tr><tr title="table-row"><td class="td-with-role" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t ; entry_with_role_rowgroup " rowspan="3" align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">-Escaso sangrado</td></tr><tr title="table-row"><td class="td-with-role" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t ; entry_with_role_rowgroup " rowspan="3" align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">(TrichoScan®)</td></tr><tr title="table-row"><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">-X \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t ; entry_with_role_rowgroup " rowspan="4" align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">-6 meses</td><td class="td-with-role" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t ; entry_with_role_rowgroup " rowspan="2" align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">-Eritema</td></tr><tr title="table-row"><td class="td-with-role" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t ; entry_with_role_rowgroup " rowspan="2" align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">-Pull test</td></tr><tr title="table-row"><td class="td-with-role" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t ; entry_with_role_rowgroup " rowspan="2" align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">-Aumento del tamaño de adenopatías (n = 8)</td></tr><tr title="table-row"><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">-Autoevaluación \t\t\t\t\t\t\n \t\t\t\t</td></tr></tbody></table> """ ] "imagenFichero" => array:1 [ 0 => "xTab2618530.png" ] ] ] ] "descripcion" => array:1 [ "es" => "Artículos seleccionados de tratamiento con aparataje de la alopecia androgénica" ] ] 5 => array:8 [ "identificador" => "t0030" "etiqueta" => "Tabla 6" "tipo" => "MULTIMEDIATABLA" "mostrarFloat" => true "mostrarDisplay" => false "detalles" => array:1 [ 0 => array:3 [ "identificador" => "al0030" "detalle" => "Tabla " "rol" => "short" ] ] "tabla" => array:2 [ "leyenda" => "FUE: Follicular Unit Extraction; H: hombres; UF: unidades foliculares." "tablatextoimagen" => array:1 [ 0 => array:2 [ "tabla" => array:1 [ 0 => """ <table border="0" frame="\n \t\t\t\t\tvoid\n \t\t\t\t" class=""><thead title="thead"><tr title="table-row"><th class="td" title="\n \t\t\t\t\ttable-head\n \t\t\t\t " align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t" scope="col" style="border-bottom: 2px solid black">Autor \t\t\t\t\t\t\n \t\t\t\t\t\t</th><th class="td" title="\n \t\t\t\t\ttable-head\n \t\t\t\t " align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t" scope="col" style="border-bottom: 2px solid black">Intervención/ Estudio \t\t\t\t\t\t\n \t\t\t\t\t\t</th><th class="td" title="\n \t\t\t\t\ttable-head\n \t\t\t\t " align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t" scope="col" style="border-bottom: 2px solid black">Pacientes/ escalas \t\t\t\t\t\t\n \t\t\t\t\t\t</th><th class="td" title="\n \t\t\t\t\ttable-head\n \t\t\t\t " align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t" scope="col" style="border-bottom: 2px solid black">Evaluación \t\t\t\t\t\t\n \t\t\t\t\t\t</th><th class="td" title="\n \t\t\t\t\ttable-head\n \t\t\t\t " align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t" scope="col" style="border-bottom: 2px solid black">Resultados \t\t\t\t\t\t\n \t\t\t\t\t\t</th></tr></thead><tbody title="tbody"><tr title="table-row"><td class="td-with-role" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t ; entry_with_role_rowhead rowgroup " rowspan="5" align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">Li KT, et al.<a class="elsevierStyleCrossRef" href="#bb0205">41</a></td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">-FUE \t\t\t\t\t\t\n \t\t\t\t</td><td class="td-with-role" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t ; entry_with_role_rowgroup " rowspan="5" align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">-n = 273 H</td><td class="td-with-role" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t ; entry_with_role_rowgroup " rowspan="5" align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">-Encuesta de satisfacción</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">-3000-6000 UF/6-12 h \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t ; entry_with_role_rowgroup " rowspan="4" align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">-Megasesiones de implantación de 3000-6000 UF</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">-Tasas de supervivencia del 93,5-96,6% \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">-Satisfacción del 81% \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">-Necesidad de un segundo procedimiento en un 19% de los pacientes \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">-No infecciones \t\t\t\t\t\t\n \t\t\t\t</td></tr></tbody></table> """ ] "imagenFichero" => array:1 [ 0 => "xTab2618529.png" ] ] ] ] "descripcion" => array:1 [ "es" => "Artículos seleccionados de tratamiento de la alopecia androgénica con trasplante capilar" ] ] ] "bibliografia" => array:2 [ "titulo" => "Bibliografía" "seccion" => array:1 [ 0 => array:2 [ "identificador" => "bs0005" "bibliografiaReferencia" => array:74 [ 0 => array:3 [ "identificador" => "bb0005" "etiqueta" => "1" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Estudio transversal acerca de los hábitos de prescripción en alopecia androgénica de los dermatólogos en España en 2017" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:3 [ 0 => "C. Ortega-Pindado" 1 => "D. Saceda-Corralo" 2 => "D. Buendía-Castaño" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "Actas Dermosifiliogr." "fecha" => "2018" "volumen" => "109" "paginaInicial" => "536" "paginaFinal" => "542" ] ] ] ] ] ] 1 => array:3 [ "identificador" => "bb0010" "etiqueta" => "2" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Androgenetic alopecia: a review" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:3 [ 0 => "F. Lolli" 1 => "F. Pallotti" 2 => "A. Rossi" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1007/s12020-017-1280-y" "Revista" => array:6 [ "tituloSerie" => "Endocrine" "fecha" => "2017" "volumen" => "57" "paginaInicial" => "9" "paginaFinal" => "17" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/28349362" "web" => "Medline" ] ] ] ] ] ] ] ] 2 => array:3 [ "identificador" => "bb0015" "etiqueta" => "3" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Confirmation of the association between male pattern baldness and the androgen receptor gene" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:4 [ 0 => "E. Levy-Nissenbaum" 1 => "M. Bar-Natan" 2 => "M. Frydman" 3 => "E. Pras" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Eur J Dermatol." "fecha" => "2005" "volumen" => "15" "paginaInicial" => "339" "paginaFinal" => "340" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/16172040" "web" => "Medline" ] ] ] ] ] ] ] ] 3 => array:3 [ "identificador" => "bb0020" "etiqueta" => "4" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Methods of treatment patients with androgenetic alopecia based on reference of department of dermatology in cracow" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:4 [ 0 => "K. Kozicka" 1 => "A. Łukasik" 2 => "M. Pastuszczak" 3 => "A. Wojas-Pelc" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "Pol Merkuriusz Lek." "fecha" => "2019" "volumen" => "46" "paginaInicial" => "80" "paginaFinal" => "83" ] ] ] ] ] ] 4 => array:3 [ "identificador" => "bb0025" "etiqueta" => "5" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Histopatología de las alopecias. Parte I: alopecias no cicatriciales" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:3 [ 0 => "C. Bernárdez" 1 => "A.M. Molina-Ruiz" 2 => "L. Requena" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1016/j.ad.2014.07.006" "Revista" => array:6 [ "tituloSerie" => "Actas Dermosifiliogr." "fecha" => "2015" "volumen" => "106" "paginaInicial" => "158" "paginaFinal" => "167" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/25444580" "web" => "Medline" ] ] ] ] ] ] ] ] 5 => array:3 [ "identificador" => "bb0030" "etiqueta" => "6" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Teloptosis, a turning point in hair shedding biorhythms" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:2 [ 0 => "C. Piérard-Franchimont" 1 => "G.E. Piérard" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1159/000051723" "Revista" => array:6 [ "tituloSerie" => "Dermatology" "fecha" => "2001" "volumen" => "203" "paginaInicial" => "115" "paginaFinal" => "117" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/11586007" "web" => "Medline" ] ] ] ] ] ] ] ] 6 => array:3 [ "identificador" => "bb0035" "etiqueta" => "7" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "The psychological impact of alopecia" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:2 [ 0 => "N. Hunt" 1 => "S. McHale" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1136/bmj.331.7522.951" "Revista" => array:6 [ "tituloSerie" => "BMJ" "fecha" => "2005" "volumen" => "331" "paginaInicial" => "951" "paginaFinal" => "953" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/16239692" "web" => "Medline" ] ] ] ] ] ] ] ] 7 => array:3 [ "identificador" => "bb0040" "etiqueta" => "8" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Quality of life assessment in male patients with androgenetic alopecia: result of a prospective, multicenter study" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:3 [ 0 => "S.H. Han" 1 => "J.W. Byun" 2 => "W.S. Lee" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.5021/ad.2012.24.3.311" "Revista" => array:7 [ "tituloSerie" => "Ann Dermatol." "fecha" => "2012" "volumen" => "24" "paginaInicial" => "311" "paginaFinal" => "318" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/22879715" "web" => "Medline" ] ] "itemHostRev" => array:3 [ "pii" => "S0213911105747816" "estado" => "S300" "issn" => "02139111" ] ] ] ] ] ] ] 8 => array:3 [ "identificador" => "bb0045" "etiqueta" => "9" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Novedades terapéuticas en tricología" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:2 [ 0 => "S. Vañó-Galván" 1 => "F. Camacho" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "Actas Dermosifiliogr." "fecha" => "2017" "volumen" => "108" "paginaInicial" => "221" "paginaFinal" => "228" ] ] ] ] ] ] 9 => array:3 [ "identificador" => "bb0050" "etiqueta" => "10" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "The effectiveness of treatments for androgenetic alopecia: a systematic review and meta-analysis" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:2 [ 0 => "A. Adil" 1 => "M. Godwin" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1016/j.jaad.2017.02.054" "Revista" => array:6 [ "tituloSerie" => "J Am Acad Dermatol." "fecha" => "2017" "volumen" => "77" "paginaInicial" => "136" "paginaFinal" => "141" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/28396101" "web" => "Medline" ] ] ] ] ] ] ] ] 10 => array:3 [ "identificador" => "bb0055" "etiqueta" => "11" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Do kimchi and cheonggukjang probiotics as a functional food improve androgenetic alopecia? A clinical pilot study" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:5 [ 0 => "D.W. Park" 1 => "H.S. Lee" 2 => "M.S. Shim" 3 => "K.J. Yum" 4 => "J.T. Seo" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.5534/wjmh.180119" "Revista" => array:6 [ "tituloSerie" => "World J Mens Health." "fecha" => "2020" "volumen" => "38" "paginaInicial" => "95" "paginaFinal" => "102" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/31385480" "web" => "Medline" ] ] ] ] ] ] ] ] 11 => array:3 [ "identificador" => "bb0060" "etiqueta" => "12" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Androgenetic alopecia treatment in asian men" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:5 [ 0 => "Y. Tanaka" 1 => "T. Aso" 2 => "J. Ono" 3 => "R. Hosoi" 4 => "T. Kaneko" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "J Clin Aesthet Dermatol." "fecha" => "2018" "volumen" => "11" "paginaInicial" => "32" "paginaFinal" => "35" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/30319729" "web" => "Medline" ] ] ] ] ] ] ] ] 12 => array:3 [ "identificador" => "bb0065" "etiqueta" => "13" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Evaluation of long-term efficacy of finasteride in Korean men with androgenetic alopecia using the basic and specific classification system" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:6 [ 0 => "J.W. Shin" 1 => "E.H. Chung" 2 => "M.B. Kim" 3 => "T.O. Kim" 4 => "W.I. Kim" 5 => "C.H. Huh" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "J Dermatol." "fecha" => "2019" "volumen" => "46" "paginaInicial" => "139" "paginaFinal" => "143" ] ] ] ] ] ] 13 => array:3 [ "identificador" => "bb0070" "etiqueta" => "14" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Clinical efficacy of oral administration of finasteride at a dose of 2.5 mg/day in women with female pattern hair loss" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:3 [ 0 => "Y.Y. Won" 1 => "B.L. Lew" 2 => "W.Y. Sim" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:4 [ "tituloSerie" => "Dermatol Ther." "fecha" => "2018" "volumen" => "31" "itemHostRev" => array:3 [ "pii" => "S0300289615304877" "estado" => "S300" "issn" => "03002896" ] ] ] ] ] ] ] 14 => array:3 [ "identificador" => "bb0075" "etiqueta" => "15" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Efficacy and safety of once-daily minoxidil foam 5% versus twice-daily minoxidil solution 2% in female pattern hair loss: a phase III, randomized, investigator-blinded study" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:3 [ 0 => "U. Blume-Peytavi" 1 => "J. Shapiro" 2 => "A.G. Messenger" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "J Drugs Dermatol." "fecha" => "2016" "volumen" => "15" "paginaInicial" => "883" "paginaFinal" => "889" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/27391640" "web" => "Medline" ] ] ] ] ] ] ] ] 15 => array:3 [ "identificador" => "bb0080" "etiqueta" => "16" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "A liposome-based formulation containing equol, dihomo-γ-linolenic acid and propionyl-l-carnitine to prevent and treat hair loss: a prospective investigation" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:3 [ 0 => "G. Brotzu" 1 => "A.M. Fadda" 2 => "M.L. Manca" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:3 [ "tituloSerie" => "Dermatol Ther." "fecha" => "2019" "volumen" => "32" ] ] ] ] ] ] 16 => array:3 [ "identificador" => "bb0085" "etiqueta" => "17" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Efficacy of a cosmetic phyto-caffeine shampoo in female androgenetic alopecia" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:3 [ 0 => "C. Bussoletti" 1 => "M.V. Tolaini" 2 => "L. Celleno" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:2 [ "tituloSerie" => "G Ital Dermatol Venereol." "fecha" => "2018" ] ] ] ] ] ] 17 => array:3 [ "identificador" => "bb0090" "etiqueta" => "18" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Efficacy and safety of a new 10% topical minoxidil versus 5% topical minoxidil and placebo in the treatment of male androgenetic alopecia: a trichoscopic evaluation" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:3 [ 0 => "S. Ghonemy" 1 => "H. Bessar" 2 => "A. Alarawi" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "J Dermatol Treat." "fecha" => "2019" "volumen" => "12" "paginaInicial" => "1" "paginaFinal" => "24" ] ] ] ] ] ] 18 => array:3 [ "identificador" => "bb0095" "etiqueta" => "19" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Efficacy and safety of a topical botanical in female androgenetic alopecia: a randomized, single-blinded, vehicle-controlled study" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:3 [ 0 => "A.C. Katoulis" 1 => "A.I. Liakou" 2 => "A. Alevizou" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1159/000480024" "Revista" => array:7 [ "tituloSerie" => "Skin Appendage Disord." "fecha" => "2018" "volumen" => "4" "paginaInicial" => "160" "paginaFinal" => "165" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/30197894" "web" => "Medline" ] ] "itemHostRev" => array:3 [ "pii" => "S0025775312007154" "estado" => "S300" "issn" => "00257753" ] ] ] ] ] ] ] 19 => array:3 [ "identificador" => "bb0100" "etiqueta" => "20" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "A preliminary study on topical cetirizine in the therapeutic management of androgenetic alopecia" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:3 [ 0 => "A. Rossi" 1 => "D. Campo" 2 => "M.C. Fortuna" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "J Dermatol Treat." "fecha" => "2018" "volumen" => "29" "paginaInicial" => "149" "paginaFinal" => "151" ] ] ] ] ] ] 20 => array:3 [ "identificador" => "bb0105" "etiqueta" => "21" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Treatment of male pattern alopecia with platelet-rich plasma: a double-blind controlled study with analysis of platelet number and growth factor levels" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:3 [ 0 => "B.L. Rodrigues" 1 => "S.A.L. Montalvão" 2 => "R.B.B. Cancela" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "J Am Acad Dermatol." "fecha" => "2019" "volumen" => "80" "paginaInicial" => "694" "paginaFinal" => "700" ] ] ] ] ] ] 21 => array:3 [ "identificador" => "bb0110" "etiqueta" => "22" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Efficacy of platelet-rich plasma in androgenetic alopecia patients" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:4 [ 0 => "G. Butt" 1 => "I. Hussain" 2 => "F.J. Ahmed" 3 => "M.S. Choudhery" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1111/jocd.12810" "Revista" => array:6 [ "tituloSerie" => "J Cosmet Dermatol." "fecha" => "2019" "volumen" => "18" "paginaInicial" => "996" "paginaFinal" => "1000" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/30393988" "web" => "Medline" ] ] ] ] ] ] ] ] 22 => array:3 [ "identificador" => "bb0115" "etiqueta" => "23" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Injectable platelet-, leukocyte-, and fibrin-rich plasma (iL-PRF) in the management of androgenetic alopecia" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:4 [ 0 => "G. Schiavone" 1 => "A. Paradisi" 2 => "F. Ricci" 3 => "D. Abeni" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1097/DSS.0000000000001584" "Revista" => array:6 [ "tituloSerie" => "Dermatol Surg." "fecha" => "2018" "volumen" => "44" "paginaInicial" => "1183" "paginaFinal" => "1190" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/30045107" "web" => "Medline" ] ] ] ] ] ] ] ] 23 => array:3 [ "identificador" => "bb0120" "etiqueta" => "24" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Evaluating the efficacy of different platelet-rich plasma regimens for management of androgenetic alopecia: a single-center, blinded, randomized clinical trial" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:2 [ 0 => "A.K. Hausauer" 1 => "D.H. Jones" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1097/DSS.0000000000001567" "Revista" => array:6 [ "tituloSerie" => "Dermatol Surg." "fecha" => "2018" "volumen" => "44" "paginaInicial" => "1191" "paginaFinal" => "1200" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/30141776" "web" => "Medline" ] ] ] ] ] ] ] ] 24 => array:3 [ "identificador" => "bb0125" "etiqueta" => "25" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Mechanical and controlled PRP injections in patients affected by androgenetic alopecia" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:6 [ 0 => "P. Gentile" 1 => "S. Garcovich" 2 => "M.G. Scioli" 3 => "A. Bielli" 4 => "A. Orlandi" 5 => "V. Cervelli" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "J Vis Exp." "fecha" => "2018" "volumen" => "7" "paginaInicial" => "131" "itemHostRev" => array:3 [ "pii" => "S1699258X14000813" "estado" => "S300" "issn" => "1699258X" ] ] ] ] ] ] ] 25 => array:3 [ "identificador" => "bb0130" "etiqueta" => "26" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Platelet-rich plasma injections in the treatment of male androgenetic alopecia: a randomized placebo-controlled crossover study" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:3 [ 0 => "Ö. Dicle" 1 => "A. Bilgic Temel" 2 => "K.H. Gülkesen" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "J Cosmet Dermatol." "fecha" => "2019" "volumen" => "19" "paginaInicial" => "1071" "paginaFinal" => "1077" ] ] ] ] ] ] 26 => array:3 [ "identificador" => "bb0135" "etiqueta" => "27" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "A study to compare the efficacy of platelet-rich plasma and minoxidil therapy for the treatment of androgenetic alopecia" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:6 [ 0 => "K. Verma" 1 => "G.R. Tegta" 2 => "G. Verma" 3 => "M. Gupta" 4 => "A. Negi" 5 => "R. Sharma" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "Int J Trichol." "fecha" => "2019" "volumen" => "11" "paginaInicial" => "68" "paginaFinal" => "79" ] ] ] ] ] ] 27 => array:3 [ "identificador" => "bb0140" "etiqueta" => "28" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Efficacy of platelet-rich plasma for treating androgenic alopecia of varying grades" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:3 [ 0 => "Q. Qu" 1 => "P. Shi" 2 => "Y. Yi" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "Clin Drug Invest." "fecha" => "2019" "volumen" => "39" "paginaInicial" => "865" "paginaFinal" => "872" ] ] ] ] ] ] 28 => array:3 [ "identificador" => "bb0145" "etiqueta" => "29" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Platelet-rich plasma on female androgenetic alopecia: tested on 10 patients" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:3 [ 0 => "M. Starace" 1 => "A. Alessandrini" 2 => "C. D'Acunto" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1111/jocd.12550" "Revista" => array:6 [ "tituloSerie" => "J Cosmet Dermatol." "fecha" => "2019" "volumen" => "18" "paginaInicial" => "59" "paginaFinal" => "64" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/29707872" "web" => "Medline" ] ] ] ] ] ] ] ] 29 => array:3 [ "identificador" => "bb0150" "etiqueta" => "30" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "The effect of platelet-rich plasma injection in the treatment of androgenetic alopecia" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:5 [ 0 => "M. Bayat" 1 => "M.J. Yazdanpanah" 2 => "D. Hamidi Alamdari" 3 => "M. Banihashemi" 4 => "M. Salehi" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "J Cosmet Dermatol." "fecha" => "2019" "volumen" => "18" "paginaInicial" => "1624" "paginaFinal" => "1628" ] ] ] ] ] ] 30 => array:3 [ "identificador" => "bb0155" "etiqueta" => "31" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Platelet-rich plasma and microneedling improves hair growth in patients of androgenetic alopecia when used as an adjuvant to minoxidil" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:6 [ 0 => "A.K. Jha" 1 => "K. Vinay" 2 => "M. Zeeshan" 3 => "P.K. Roy" 4 => "R.K.P. Chaudhary" 5 => "A. Priya" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:2 [ "tituloSerie" => "J Cosmet Dermatol." "fecha" => "2019" ] ] ] ] ] ] 31 => array:3 [ "identificador" => "bb0160" "etiqueta" => "32" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Stem cell therapy as a novel therapeutic intervention for resistant cases of alopecia areata and androgenetic alopecia" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:3 [ 0 => "I.H. Elmaadawi" 1 => "B.M. Mohamed" 2 => "Z.A.S. Ibrahim" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "J Dermatol Treat." "fecha" => "2018" "volumen" => "29" "paginaInicial" => "431" "paginaFinal" => "440" ] ] ] ] ] ] 32 => array:3 [ "identificador" => "bb0165" "etiqueta" => "33" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Platelet-rich plasma and micrografts enriched with autologous human follicle mesenchymal stem cells improve hair re-growth in androgenetic alopecia" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:3 [ 0 => "P. Gentile" 1 => "M.G. Scioli" 2 => "A. Bielli" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:4 [ "tituloSerie" => "Biomedicines" "fecha" => "2019" "volumen" => "8" "paginaInicial" => "7" ] ] ] ] ] ] 33 => array:3 [ "identificador" => "bb0170" "etiqueta" => "34" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Low-level laser therapy for the treatment of androgenetic alopecia in Thai men and women: a 24-week, randomized, double-blind, sham device-controlled trial" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:3 [ 0 => "P. Suchonwanit" 1 => "N. Chalermroj" 2 => "S. Khunkhet" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1007/s10103-018-02699-9" "Revista" => array:6 [ "tituloSerie" => "Lasers Med Sci." "fecha" => "2019" "volumen" => "34" "paginaInicial" => "1107" "paginaFinal" => "1114" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/30569416" "web" => "Medline" ] ] ] ] ] ] ] ] 34 => array:3 [ "identificador" => "bb0175" "etiqueta" => "35" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Study of the efficacy of carboxytherapy in alopecia" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:4 [ 0 => "N.N. Doghaim" 1 => "R.A. El-Tatawy" 2 => "Y.M.E. Neinaa" 3 => "M.M. Abd El-Samd" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1111/jocd.12501" "Revista" => array:6 [ "tituloSerie" => "J Cosmet Dermatol." "fecha" => "2018" "volumen" => "17" "paginaInicial" => "1275" "paginaFinal" => "1285" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/29460509" "web" => "Medline" ] ] ] ] ] ] ] ] 35 => array:3 [ "identificador" => "bb0180" "etiqueta" => "36" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Efficacy of 1550-nm erbium-glass fractional laser treatment and its effect on the expression of insulin-like growth factor 1 and Wnt/β-catenin in androgenetic alopecia" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:5 [ 0 => "J. Meephansan" 1 => "N. Ungpraphakorn" 2 => "S. Ponnikorn" 3 => "P. Suchonwanit" 4 => "Y. Poovorawan" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1097/DSS.0000000000001619" "Revista" => array:6 [ "tituloSerie" => "Dermatol Surg." "fecha" => "2018" "volumen" => "44" "paginaInicial" => "1295" "paginaFinal" => "1303" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/30096107" "web" => "Medline" ] ] ] ] ] ] ] ] 36 => array:3 [ "identificador" => "bb0185" "etiqueta" => "37" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "The effectiveness of adding low-level light therapy to minoxidil 5% solution in the treatment of patients with androgenetic alopecia" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:3 [ 0 => "G. Faghihi" 1 => "S. Mozafarpoor" 2 => "A. Asilian" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "Indian J Dermatol Venereol Leprol." "fecha" => "2018" "volumen" => "84" "paginaInicial" => "547" "paginaFinal" => "553" ] ] ] ] ] ] 37 => array:3 [ "identificador" => "bb0190" "etiqueta" => "38" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Clinical evaluation of a novel fractional radiofrequency device for hair growth: fractional radiofrequency for hair growth stimulation" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:2 [ 0 => "I. Verner" 1 => "T. Lotti" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:3 [ "tituloSerie" => "Dermatol Ther." "fecha" => "2018" "volumen" => "31" ] ] ] ] ] ] 38 => array:3 [ "identificador" => "bb0195" "etiqueta" => "39" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "A randomized, investigator-blinded, controlled, split-scalp study of the efficacy and safety of a 1550-nm fractional erbium-glass laser, used in combination with topical 5% minoxidil versus 5% minoxidil alone, for the treatment of androgenetic alopecia" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:3 [ 0 => "P. Suchonwanit" 1 => "S. Rojhirunsakool" 2 => "S. Khunkhet" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1007/s10103-019-02783-8" "Revista" => array:6 [ "tituloSerie" => "Lasers Med Sci." "fecha" => "2019" "volumen" => "34" "paginaInicial" => "1857" "paginaFinal" => "1864" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/30982177" "web" => "Medline" ] ] ] ] ] ] ] ] 39 => array:3 [ "identificador" => "bb0200" "etiqueta" => "40" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Preliminary results of the use of scalp microneedling in different types of alopecia" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:4 [ 0 => "M. Starace" 1 => "A. Alessandrini" 2 => "N. Brandi" 3 => "B.M. Piraccini" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1111/jocd.13061" "Revista" => array:7 [ "tituloSerie" => "J Cosmet Dermatol." "fecha" => "2019" "volumen" => "19" "paginaInicial" => "646" "paginaFinal" => "650" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/31254437" "web" => "Medline" ] ] "itemHostRev" => array:3 [ "pii" => "S0213911117303151" "estado" => "S300" "issn" => "02139111" ] ] ] ] ] ] ] 40 => array:3 [ "identificador" => "bb0205" "etiqueta" => "41" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Clinical experience on follicular unit extraction megasession for severe androgenetic alopecia" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:3 [ 0 => "K.T. Li" 1 => "Q. Qu" 2 => "Z.X. Fan" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1111/jocd.13458" "Revista" => array:4 [ "tituloSerie" => "J Cosmet Dermatol." "fecha" => "2019" "volumen" => "19" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/32449835" "web" => "Medline" ] ] ] ] ] ] ] ] 41 => array:3 [ "identificador" => "bb0210" "etiqueta" => "42" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Androgenetic alopecia: an evidence-based treatment update" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:2 [ 0 => "S. Varothai" 1 => "W.F. Bergfeld" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1007/s40257-014-0077-5" "Revista" => array:7 [ "tituloSerie" => "Am J Clin Dermatol." "fecha" => "2014" "volumen" => "15" "paginaInicial" => "217" "paginaFinal" => "230" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/24848508" "web" => "Medline" ] ] "itemHostRev" => array:3 [ "pii" => "S0213911118301638" "estado" => "S300" "issn" => "02139111" ] ] ] ] ] ] ] 42 => array:3 [ "identificador" => "bb0215" "etiqueta" => "43" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Minoxidil in the treatment of androgenetic alopecia" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:2 [ 0 => "A. Goren" 1 => "T. Naccarato" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:3 [ "tituloSerie" => "Dermatol Ther." "fecha" => "2018" "volumen" => "31" ] ] ] ] ] ] 43 => array:3 [ "identificador" => "bb0220" "etiqueta" => "44" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Minoxidil and its use in hair disorders: a review" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:3 [ 0 => "P. Suchonwanit" 1 => "S. Thammarucha" 2 => "K. Leerunyakul" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.2147/DDDT.S214907" "Revista" => array:6 [ "tituloSerie" => "Drug Des Devel Ther." "fecha" => "2019" "volumen" => "13" "paginaInicial" => "2777" "paginaFinal" => "2786" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/31496654" "web" => "Medline" ] ] ] ] ] ] ] ] 44 => array:3 [ "identificador" => "bb0225" "etiqueta" => "45" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Laser-assisted drug delivery for the treatment of androgenetic alopecia: ablative laser fractional photothermolysis to enhance cutaneous topical delivery of platelet-rich plasma - with or without concurrent bimatoprost and/or minoxidil" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:1 [ 0 => "P.R. Cohen" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:4 [ "tituloSerie" => "Dermatol Online J." "fecha" => "2019" "volumen" => "15" "paginaInicial" => "25" ] ] ] ] ] ] 45 => array:3 [ "identificador" => "bb0230" "etiqueta" => "46" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Low-dose daily aspirin reduces topical minoxidil efficacy in androgenetic alopecia patients" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:3 [ 0 => "A. Goren" 1 => "A. Sharma" 2 => "R. Dhurat" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:3 [ "tituloSerie" => "Dermatol Ther." "fecha" => "2018" "volumen" => "31" ] ] ] ] ] ] 46 => array:3 [ "identificador" => "bb0235" "etiqueta" => "47" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Tretinoin enhances minoxidil response in androgenetic alopecia patients by upregulating follicular sulfotransferase enzymes" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:3 [ 0 => "A. Sharma" 1 => "A. Goren" 2 => "R. Dhurat" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:3 [ "tituloSerie" => "Dermatol Ther." "fecha" => "2019" "volumen" => "32" ] ] ] ] ] ] 47 => array:3 [ "identificador" => "bb0240" "etiqueta" => "48" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Reply to «Very low dose oral minoxidil in male androgenetic alopecia: a study with quantitative trichoscopic documentation»" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:6 [ 0 => "J. Jimenez-Cauhe" 1 => "D. Saceda-Corralo" 2 => "O.M. Moreno-Arrones" 3 => "D. Ortega-Quijano" 4 => "D. Fernandez-Nieto" 5 => "S. Vaño-Galvan" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1016/j.jaad.2019.08.085" "Revista" => array:6 [ "tituloSerie" => "J Am Acad Dermatol." "fecha" => "2020" "volumen" => "82" "paginaInicial" => "e23" "paginaFinal" => "e24" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/31520659" "web" => "Medline" ] ] ] ] ] ] ] ] 48 => array:3 [ "identificador" => "bb0245" "etiqueta" => "49" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Very low dose oral minoxidil in male androgenetic alopecia: a study with quantitative trichoscopic documentation" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:2 [ 0 => "R. Pirmez" 1 => "C.I. Salas-Callo" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1016/j.jaad.2019.08.084" "Revista" => array:6 [ "tituloSerie" => "J Am Acad Dermatol." "fecha" => "2020" "volumen" => "82" "paginaInicial" => "e21" "paginaFinal" => "e22" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/31520662" "web" => "Medline" ] ] ] ] ] ] ] ] 49 => array:3 [ "identificador" => "bb0250" "etiqueta" => "50" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Female pattern hair loss: a pilot study investigating combination therapy with low-dose oral minoxidil and spironolactone" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:1 [ 0 => "R.D. Sinclair" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1111/ijd.13838" "Revista" => array:6 [ "tituloSerie" => "Int J Dermatol." "fecha" => "2018" "volumen" => "57" "paginaInicial" => "104" "paginaFinal" => "109" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/29231239" "web" => "Medline" ] ] ] ] ] ] ] ] 50 => array:3 [ "identificador" => "bb0255" "etiqueta" => "51" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:1 [ "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:4 [ 0 => "P.M. Ramos" 1 => "R.D. Sinclair" 2 => "M. Kasprzak" 3 => "H.A. Miot" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1016/j.jaad.2019.08.060" "Revista" => array:6 [ "tituloSerie" => "J Am Acad Dermatol." "fecha" => "2020" "volumen" => "82" "paginaInicial" => "252" "paginaFinal" => "253" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/31473295" "web" => "Medline" ] ] ] ] ] ] ] ] 51 => array:3 [ "identificador" => "bb0260" "etiqueta" => "52" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Efficacy and safety of finasteride therapy for androgenetic alopecia: a systematic review" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:5 [ 0 => "J.M. Mella" 1 => "M.C. Perret" 2 => "M. Manzotti" 3 => "H.N. Catalano" 4 => "G. Guyatt" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1001/archdermatol.2010.256" "Revista" => array:6 [ "tituloSerie" => "Arch Dermatol." "fecha" => "2010" "volumen" => "146" "paginaInicial" => "1141" "paginaFinal" => "1150" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/20956649" "web" => "Medline" ] ] ] ] ] ] ] ] 52 => array:3 [ "identificador" => "bb0265" "etiqueta" => "53" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Finasteride for androgenetic alopecia is not associated with sexual dysfunction: a survey-based, single-centre, controlled study" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:5 [ 0 => "R.S. Haber" 1 => "A.K. Gupta" 2 => "E. Epstein" 3 => "J.L. Carviel" 4 => "K.A. Foley" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1111/jdv.15548" "Revista" => array:6 [ "tituloSerie" => "J Eur Acad Dermatol Venereol." "fecha" => "2019" "volumen" => "33" "paginaInicial" => "1393" "paginaFinal" => "1397" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/30835851" "web" => "Medline" ] ] ] ] ] ] ] ] 53 => array:3 [ "identificador" => "bb0270" "etiqueta" => "54" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Adverse effects and safety of 5-alpha reductase inhibitors (Finasteride, Dutasteride): a systematic review" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:5 [ 0 => "J.M. Hirshburg" 1 => "P.A. Kelsey" 2 => "C.A. Therrien" 3 => "A.C. Gavino" 4 => "J.S. Reichenberg" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "J Clin Aesthet Dermatol." "fecha" => "2016" "volumen" => "9" "paginaInicial" => "56" "paginaFinal" => "62" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/27672412" "web" => "Medline" ] ] ] ] ] ] ] ] 54 => array:3 [ "identificador" => "bb0275" "etiqueta" => "55" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "The efficacy and use of finasteride in women: a systematic review" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:3 [ 0 => "A.C. Hu" 1 => "L.W. Chapman" 2 => "N.A. Mesinkovska" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1111/ijd.14370" "Revista" => array:7 [ "tituloSerie" => "Int J Dermatol." "fecha" => "2019" "volumen" => "58" "paginaInicial" => "759" "paginaFinal" => "776" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/30604525" "web" => "Medline" ] ] "itemHostRev" => array:3 [ "pii" => "S0213911111000872" "estado" => "S300" "issn" => "02139111" ] ] ] ] ] ] ] 55 => array:3 [ "identificador" => "bb0280" "etiqueta" => "56" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "The efficacy and safety of dutasteride compared with finasteride in treating men with androgenetic alopecia: a systematic review and meta-analysis" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:6 [ 0 => "Z. Zhou" 1 => "S. Song" 2 => "Z. Gao" 3 => "J. Wu" 4 => "J. Ma" 5 => "Y. Cui" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.2147/CIA.S192435" "Revista" => array:6 [ "tituloSerie" => "Clin Interv Aging." "fecha" => "2019" "volumen" => "14" "paginaInicial" => "399" "paginaFinal" => "406" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/30863034" "web" => "Medline" ] ] ] ] ] ] ] ] 56 => array:3 [ "identificador" => "bb0285" "etiqueta" => "57" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "A systematic review of topical finasteride in the treatment of androgenetic alopecia in men and women" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:5 [ 0 => "S.W. Lee" 1 => "M. Juhasz" 2 => "P. Mobasher" 3 => "C. Ekelem" 4 => "N.A. Mesinkovska" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "J Drugs Dermatol." "fecha" => "2018" "volumen" => "17" "paginaInicial" => "457" "paginaFinal" => "463" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/29601622" "web" => "Medline" ] ] ] ] ] ] ] ] 57 => array:3 [ "identificador" => "bb0290" "etiqueta" => "58" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "The efficacy of latanoprost in the treatment of alopecia areata of eyelashes and eyebrows" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:3 [ 0 => "G. Faghihi" 1 => "F. Andalib" 2 => "A. Asilian" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1684/ejd.2009.0766" "Revista" => array:6 [ "tituloSerie" => "Eur J Dermatol." "fecha" => "2009" "volumen" => "19" "paginaInicial" => "586" "paginaFinal" => "587" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/19620039" "web" => "Medline" ] ] ] ] ] ] ] ] 58 => array:3 [ "identificador" => "bb0295" "etiqueta" => "59" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "The use of phosphodiesterase inhibitors for the treatment of alopecia" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:2 [ 0 => "M.L.W. Juhász" 1 => "N.A. Mesinkovska" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "J Dermatol Treat." "fecha" => "2019" "volumen" => "2" "paginaInicial" => "1" "paginaFinal" => "8" ] ] ] ] ] ] 59 => array:3 [ "identificador" => "bb0300" "etiqueta" => "60" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Cellium® GC: evaluation of a new natural active ingredient in 210 mg/ml topical solution through scalp biopsy" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:3 [ 0 => "L.C. Cucé" 1 => "C.J. Rodrigues" 2 => "R.C.R. Patriota" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "Sug Cosmet Dermatol." "fecha" => "2011" "volumen" => "3" "paginaInicial" => "123" "paginaFinal" => "128" ] ] ] ] ] ] 60 => array:3 [ "identificador" => "bb0305" "etiqueta" => "61" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Platelet-rich plasma peptides: key for regeneration" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:3 [ 0 => "D.J. Sánchez-González" 1 => "E. Méndez-Bolaina" 2 => "N.I. Trejo-Bahena" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:4 [ "tituloSerie" => "Int J Pept." "fecha" => "2012" "volumen" => "5" "paginaInicial" => "519" ] ] ] ] ] ] 61 => array:3 [ "identificador" => "bb0310" "etiqueta" => "62" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "The role of platelet growth factors in male pattern baldness surgery" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:4 [ 0 => "C.O. Uebel" 1 => "J.B. Da Silva" 2 => "D. Cantarelli" 3 => "P. Martins" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1097/01.prs.0000239560.29172.33" "Revista" => array:6 [ "tituloSerie" => "Plast Reconstr Surg." "fecha" => "2006" "volumen" => "118" "paginaInicial" => "1458" "paginaFinal" => "1466" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/17051119" "web" => "Medline" ] ] ] ] ] ] ] ] 62 => array:3 [ "identificador" => "bb0315" "etiqueta" => "63" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "The effect of plasma rich in growth factors on a pattern hair loss: a pilot study" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:5 [ 0 => "E. Anitua" 1 => "A. Pino" 2 => "N. Martinez" 3 => "G. Orive" 4 => "D. Berridi" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1097/DSS.0000000000001049" "Revista" => array:6 [ "tituloSerie" => "Dermatol Surg." "fecha" => "2017" "volumen" => "43" "paginaInicial" => "658" "paginaFinal" => "670" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/28221183" "web" => "Medline" ] ] ] ] ] ] ] ] 63 => array:3 [ "identificador" => "bb0320" "etiqueta" => "64" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Efficacy of platelet-rich plasma in the treatment of androgenetic (male-patterned) alopecia: a pilot randomized controlled trial" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:3 [ 0 => "M.A. Mapar" 1 => "S. shahriari" 2 => "M.H. Haghighizadeh" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1080/14764172.2016.1225963" "Revista" => array:6 [ "tituloSerie" => "J Cosmet Laser Ther." "fecha" => "2016" "volumen" => "18" "paginaInicial" => "452" "paginaFinal" => "455" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/27593381" "web" => "Medline" ] ] ] ] ] ] ] ] 64 => array:3 [ "identificador" => "bb0325" "etiqueta" => "65" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Platelet-rich for treating androgenic alopecia: a systematic review" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:3 [ 0 => "G. Mao" 1 => "G. Zhang" 2 => "W. Fan" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "Aesthetic Plast Surg." "fecha" => "2019" "volumen" => "43" "paginaInicial" => "1326" "paginaFinal" => "1336" ] ] ] ] ] ] 65 => array:3 [ "identificador" => "bb0330" "etiqueta" => "66" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:1 [ "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:6 [ 0 => "A. Gupta" 1 => "S. Versteeg" 2 => "J. Rapaport" 3 => "A. Hausauer" 4 => "N. Shear" 5 => "V. Piguet" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1177/1203475418818073" "Revista" => array:6 [ "tituloSerie" => "J Cutan Med Surg." "fecha" => "2019" "volumen" => "23" "paginaInicial" => "185" "paginaFinal" => "203" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/30606055" "web" => "Medline" ] ] ] ] ] ] ] ] 66 => array:3 [ "identificador" => "bb0335" "etiqueta" => "67" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Platelet-rich plasma and its utilities in alopecia: a systematic review" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:2 [ 0 => "M.J. Hesseler" 1 => "N. Shyam" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1097/DSS.0000000000001965" "Revista" => array:6 [ "tituloSerie" => "Dermatol Surg." "fecha" => "2020" "volumen" => "46" "paginaInicial" => "93" "paginaFinal" => "102" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/31211715" "web" => "Medline" ] ] ] ] ] ] ] ] 67 => array:3 [ "identificador" => "bb0340" "etiqueta" => "68" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Platelet-rich plasma for the treatment of androgenic alopecia: a systematic review" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:3 [ 0 => "J. Chen" 1 => "N. Justicz" 2 => "L. Lee" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1055/s-0038-1660845" "Revista" => array:6 [ "tituloSerie" => "Facial Plast Surg." "fecha" => "2018" "volumen" => "34" "paginaInicial" => "631" "paginaFinal" => "640" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/29954021" "web" => "Medline" ] ] ] ] ] ] ] ] 68 => array:3 [ "identificador" => "bb0345" "etiqueta" => "69" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Systematic review of platelet-rich plasma (PRP) preparation and composition for the treatment of androgenic alopecia" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:2 [ 0 => "M.J. Kramer" 1 => "T. Keaney" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1111/jocd.12679" "Revista" => array:6 [ "tituloSerie" => "J Cosmet Dermatol." "fecha" => "2018" "volumen" => "17" "paginaInicial" => "666" "paginaFinal" => "671" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/29790267" "web" => "Medline" ] ] ] ] ] ] ] ] 69 => array:3 [ "identificador" => "bb0350" "etiqueta" => "70" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Platelet rich plasma in androgenetic alopecia: a systematic review" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:5 [ 0 => "T. Lotti" 1 => "A. Goren" 2 => "I. Verner" 3 => "A. D'Alessio Patrizia" 4 => "K. Franca" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:3 [ "tituloSerie" => "Dermatol Ther." "fecha" => "2019" "volumen" => "32" ] ] ] ] ] ] 70 => array:3 [ "identificador" => "bb0355" "etiqueta" => "71" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Shedding light on the FDA's 510(k) approvals process: low-level laser therapy devices used in the treatment of androgenetic alopecia" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:3 [ 0 => "S. Wang" 1 => "D. Seth" 2 => "H. Ezaldein" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "J Dermatol Treat." "fecha" => "2019" "volumen" => "30" "paginaInicial" => "489" "paginaFinal" => "491" ] ] ] ] ] ] 71 => array:3 [ "identificador" => "bb0360" "etiqueta" => "72" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Quantitative proteomic analysis of dermal papilla from male androgenetic alopecia comparing before and after treatment with low-level laser therapy" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:3 [ 0 => "R. Panchaprateep" 1 => "T. Pisitkun" 2 => "N. Kalpongnukul" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1002/lsm.23074" "Revista" => array:6 [ "tituloSerie" => "Lasers Surg Med." "fecha" => "2019" "volumen" => "51" "paginaInicial" => "600" "paginaFinal" => "608" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/30843235" "web" => "Medline" ] ] ] ] ] ] ] ] 72 => array:3 [ "identificador" => "bb0365" "etiqueta" => "73" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Efficacy of fractional lasers in treating alopecia: a literature review" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:5 [ 0 => "M. Perper" 1 => "A.S. Aldahan" 2 => "R.A. Fayne" 3 => "C.P. Emerson" 4 => "K. Nouri" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "Lasers Med Sci." "fecha" => "2017" "volumen" => "32" "paginaInicial" => "1919" "paginaFinal" => "1925" ] ] ] ] ] ] 73 => array:3 [ "identificador" => "bb0370" "etiqueta" => "74" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Fractional laser-assisted hair regrowth and microneedling for the treatment of alopecia areata: a review" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:5 [ 0 => "R.J. Dabek" 1 => "D.S. Roh" 2 => "D. Ozdemir" 3 => "W.G. Austen Jr." 4 => "B. Bojovic" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:3 [ "tituloSerie" => "Cureus" "fecha" => "2019" "volumen" => "11" ] ] ] ] ] ] ] ] ] ] ] "idiomaDefecto" => "es" "url" => "/02139251/0000003600000006/v1_202106100533/S0213925120303087/v1_202106100533/es/main.assets" "Apartado" => array:4 [ "identificador" => "8169" "tipo" => "SECCION" "en" => array:2 [ "titulo" => "Terapéutica dermatológica" "idiomaDefecto" => true ] "idiomaDefecto" => "en" ] "PDF" => "https://static.elsevier.es/multimedia/02139251/0000003600000006/v1_202106100533/S0213925120303087/v1_202106100533/es/main.pdf?idApp=UINPBA00004N&text.app=https://www.elsevier.es/" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0213925120303087?idApp=UINPBA00004N"]

Estadísticas

Terapéutica dermatológica

Actualización en el tratamiento de la alopecia androgénica

Update on the treatment of androgenic alopecia

Alfonso Mogedas-Vegaraa,

Autor para correspondencia

alfonso.mogedas@gmail.com

Autor para correspondencia.

, Eugènia Agut-Busquetb, Miquel Ribera Pibernatc

a Servicio de Cirugía Oral y Maxilofacial, Hospital Universitari Parc Taulí, Universidad Autónoma de Barcelona, Sabadell, España

b Servicio de Dermatología, Hospital de la Santa Creu i Sant Pau, Universidad Autónoma de Barcelona, Barcelona, España

c Servicio de Dermatología, Hospital Universitari Parc Taulí, Universidad Autónoma de Barcelona, Sabadell, España

Leído

434

Veces
se ha leído el artículo

158

Total PDF

276

Total HTML

Compartir estadísticas

 array:22 [
  "pii" => "S0213925120303087"
  "issn" => "02139251"
  "doi" => "10.1016/j.piel.2020.05.012"
  "estado" => "S300"
  "fechaPublicacion" => "2021-06-01"
  "aid" => "2104"
  "copyrightAnyo" => "2020"
  "documento" => "article"
  "crossmark" => 1
  "subdocumento" => "sco"
  "cita" => "Piel. 2021;36:408-18"
  "abierto" => array:3 [
    "ES" => false
    "ES2" => false
    "LATM" => false
  ]
  "gratuito" => false
  "lecturas" => array:1 [
    "total" => 0
  ]
  "itemSiguiente" => array:17 [
    "pii" => "S0213925120303701"
    "issn" => "02139251"
    "doi" => "10.1016/j.piel.2020.06.014"
    "estado" => "S300"
    "fechaPublicacion" => "2021-06-01"
    "aid" => "2141"
    "documento" => "article"
    "crossmark" => 1
    "subdocumento" => "crp"
    "cita" => "Piel. 2021;36:419-20"
    "abierto" => array:3 [
      "ES" => false
      "ES2" => false
      "LATM" => false
    ]
    "gratuito" => false
    "lecturas" => array:1 [
      "total" => 0
    ]
    "es" => array:11 [
      "idiomaDefecto" => true
      "cabecera" => "<span class="elsevierStyleTextfn">Carta cl&#237;nica</span>"
      "titulo" => "Neuroma solitario circunscrito en el glande"
      "tienePdf" => "es"
      "tieneTextoCompleto" => "es"
      "paginas" => array:1 [
        0 => array:2 [
          "paginaInicial" => "419"
          "paginaFinal" => "420"
        ]
      ]
      "titulosAlternativos" => array:1 [
        "en" => array:1 [
          "titulo" => "Solitary circumscribed neuroma in glans penis"
        ]
      ]
      "contieneTextoCompleto" => array:1 [
        "es" => true
      ]
      "contienePdf" => array:1 [
        "es" => true
      ]
      "resumenGrafico" => array:2 [
        "original" => 0
        "multimedia" => array:8 [
          "identificador" => "f0005"
          "etiqueta" => "Figura 1"
          "tipo" => "MULTIMEDIAFIGURA"
          "mostrarFloat" => true
          "mostrarDisplay" => false
          "figura" => array:1 [
            0 => array:4 [
              "imagen" => "gr1.jpeg"
              "Alto" => 1691
              "Ancho" => 1614
              "Tamanyo" => 240948
            ]
          ]
          "detalles" => array:1 [
            0 => array:3 [
              "identificador" => "al0005"
              "detalle" => "Figura "
              "rol" => "short"
            ]
          ]
          "descripcion" => array:1 [
            "es" => "<p id="sp7854" class="elsevierStyleSimplePara elsevierViewall">P&#225;pula color piel aislada en el glande&#46;</p>"
          ]
        ]
      ]
      "autores" => array:1 [
        0 => array:2 [
          "autoresLista" => "Alba L&#243;pez Valle, Daniel Falkenhain L&#243;pez, Mar&#237;a Concepci&#243;n Garrido Ruiz, Ver&#243;nica Mons&#225;lvez Honrubia"
          "autores" => array:4 [
            0 => array:2 [
              "nombre" => "Alba"
              "apellidos" => "L&#243;pez Valle"
            ]
            1 => array:2 [
              "nombre" => "Daniel"
              "apellidos" => "Falkenhain L&#243;pez"
            ]
            2 => array:2 [
              "nombre" => "Mar&#237;a Concepci&#243;n"
              "apellidos" => "Garrido Ruiz"
            ]
            3 => array:2 [
              "nombre" => "Ver&#243;nica"
              "apellidos" => "Mons&#225;lvez Honrubia"
            ]
          ]
        ]
      ]
    ]
    "idiomaDefecto" => "es"
    "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0213925120303701?idApp=UINPBA00004N"
    "url" => "/02139251/0000003600000006/v1_202106100533/S0213925120303701/v1_202106100533/es/main.assets"
  ]
  "itemAnterior" => array:17 [
    "pii" => "S021392512030472X"
    "issn" => "02139251"
    "doi" => "10.1016/j.piel.2020.12.003"
    "estado" => "S300"
    "fechaPublicacion" => "2021-06-01"
    "aid" => "2193"
    "documento" => "article"
    "crossmark" => 1
    "subdocumento" => "crp"
    "cita" => "Piel. 2021;36:406-7"
    "abierto" => array:3 [
      "ES" => false
      "ES2" => false
      "LATM" => false
    ]
    "gratuito" => false
    "lecturas" => array:1 [
      "total" => 0
    ]
    "es" => array:10 [
      "idiomaDefecto" => true
      "cabecera" => "<span class="elsevierStyleTextfn">Caso para el diagn&#243;stico&#46; Soluci&#243;n</span>"
      "titulo" => "Placas necr&#243;ticas en los miembros inferiores&#46; Diagn&#243;stico y comentario"
      "tienePdf" => "es"
      "tieneTextoCompleto" => "es"
      "paginas" => array:1 [
        0 => array:2 [
          "paginaInicial" => "406"
          "paginaFinal" => "407"
        ]
      ]
      "titulosAlternativos" => array:1 [
        "en" => array:1 [
          "titulo" => "Necrotic plaques on thighs&#46; Diagnosis and comment"
        ]
      ]
      "contieneTextoCompleto" => array:1 [
        "es" => true
      ]
      "contienePdf" => array:1 [
        "es" => true
      ]
      "autores" => array:1 [
        0 => array:2 [
          "autoresLista" => "Nicol&#225;s Silvestre Torner, Hirune Cembrero Saralegui, Mar&#237;a Dorado Fern&#225;ndez"
          "autores" => array:3 [
            0 => array:2 [
              "nombre" => "Nicol&#225;s"
              "apellidos" => "Silvestre Torner"
            ]
            1 => array:2 [
              "nombre" => "Hirune"
              "apellidos" => "Cembrero Saralegui"
            ]
            2 => array:2 [
              "nombre" => "Mar&#237;a"
              "apellidos" => "Dorado Fern&#225;ndez"
            ]
          ]
        ]
      ]
    ]
    "idiomaDefecto" => "es"
    "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S021392512030472X?idApp=UINPBA00004N"
    "url" => "/02139251/0000003600000006/v1_202106100533/S021392512030472X/v1_202106100533/es/main.assets"
  ]
  "es" => array:13 [
    "idiomaDefecto" => true
    "cabecera" => "<span class="elsevierStyleTextfn">Terap&#233;utica dermatol&#243;gica</span>"
    "titulo" => "Actualizaci&#243;n en el tratamiento de la alopecia androg&#233;nica"
    "tieneTextoCompleto" => true
    "paginas" => array:1 [
      0 => array:2 [
        "paginaInicial" => "408"
        "paginaFinal" => "418"
      ]
    ]
    "autores" => array:1 [
      0 => array:4 [
        "autoresLista" => "Alfonso Mogedas-Vegara, Eug&#232;nia Agut-Busquet, Miquel Ribera Pibernat"
        "autores" => array:3 [
          0 => array:4 [
            "nombre" => "Alfonso"
            "apellidos" => "Mogedas-Vegara"
            "email" => array:1 [
              0 => "alfonso.mogedas@gmail.com"
            ]
            "referencia" => array:2 [
              0 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">a</span>"
                "identificador" => "af0005"
              ]
              1 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">&#42;</span>"
                "identificador" => "cr0005"
              ]
            ]
          ]
          1 => array:3 [
            "nombre" => "Eug&#232;nia"
            "apellidos" => "Agut-Busquet"
            "referencia" => array:1 [
              0 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">b</span>"
                "identificador" => "af0010"
              ]
            ]
          ]
          2 => array:3 [
            "nombre" => "Miquel"
            "apellidos" => "Ribera Pibernat"
            "referencia" => array:1 [
              0 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">c</span>"
                "identificador" => "af0015"
              ]
            ]
          ]
        ]
        "afiliaciones" => array:3 [
          0 => array:3 [
            "entidad" => "Servicio de Cirug&#237;a Oral y Maxilofacial&#44; Hospital Universitari Parc Taul&#237;&#44; Universidad Aut&#243;noma de Barcelona&#44; Sabadell&#44; Espa&#241;a"
            "etiqueta" => "a"
            "identificador" => "af0005"
          ]
          1 => array:3 [
            "entidad" => "Servicio de Dermatolog&#237;a&#44; Hospital de la Santa Creu i Sant Pau&#44; Universidad Aut&#243;noma de Barcelona&#44; Barcelona&#44; Espa&#241;a"
            "etiqueta" => "b"
            "identificador" => "af0010"
          ]
          2 => array:3 [
            "entidad" => "Servicio de Dermatolog&#237;a&#44; Hospital Universitari Parc Taul&#237;&#44; Universidad Aut&#243;noma de Barcelona&#44; Sabadell&#44; Espa&#241;a"
            "etiqueta" => "c"
            "identificador" => "af0015"
          ]
        ]
        "correspondencia" => array:1 [
          0 => array:3 [
            "identificador" => "cr0005"
            "etiqueta" => "&#8270;"
            "correspondencia" => "Autor para correspondencia&#46;"
          ]
        ]
      ]
    ]
    "titulosAlternativos" => array:1 [
      "en" => array:1 [
        "titulo" => "Update on the treatment of androgenic alopecia"
      ]
    ]
    "textoCompleto" => "<span class="elsevierStyleSections"><span id="s0005" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="st0015">Introducci&#243;n</span><p id="p0010" class="elsevierStylePara elsevierViewall">La alopecia androg&#233;nica &#40;AGA&#41; es la forma m&#225;s frecuente de p&#233;rdida de cabello&#46; La edad de aparici&#243;n es variable&#44; aunque lo m&#225;s frecuente es que aparezca durante la pubertad en los hombres y un poco m&#225;s tarde en las mujeres&#46; Su prevalencia y severidad suele ir aumentando con la edad en ambos sexos&#44; estim&#225;ndose en las series publicadas que aproximadamente afecta a un 70&#37; de los varones cauc&#225;sicos y entre el 30 y 50&#37; de las mujeres<a class="elsevierStyleCrossRefs" href="#bb0005"><span class="elsevierStyleSup">1&#44;2</span></a>&#46;</p><p id="p0015" class="elsevierStylePara elsevierViewall">Se considera un trastorno multifactorial causado por la interacci&#243;n de m&#250;ltiples genes&#44; hormonas y factores medioambientales y cuya fisiopatolog&#237;a se encuentra influida por las alteraciones en el metabolismo de los andr&#243;genos<a class="elsevierStyleCrossRefs" href="#bb0015"><span class="elsevierStyleSup">3&#44;4</span></a>&#46;</p><p id="p0020" class="elsevierStylePara elsevierViewall">Histopatol&#243;gicamente se produce una miniaturizaci&#243;n progresiva del fol&#237;culo en la que los pelos terminales gruesos y pigmentados se van transformando en pelos vellosos&#46; Encontramos una seudohiperplasia de las gl&#225;ndulas seb&#225;ceas que parecen de mayor tama&#241;o al compararlas con los fol&#237;culos miniaturizados&#46; Debido al incremento de los niveles de dihidrotestosterona&#44; se produce una disminuci&#243;n de la fase de an&#225;geno y un incremento de la de tel&#243;geno<a class="elsevierStyleCrossRefs" href="#bb0025"><span class="elsevierStyleSup">5&#44;6</span></a>&#46;</p><p id="p0025" class="elsevierStylePara elsevierViewall">Puede afectar tanto a la vertiente cosm&#233;tica como a la esfera psicosocial de las personas&#44; pudiendo llegar a deteriorar su calidad de vida&#46; Por este motivo los pacientes tienden a buscar alguna soluci&#243;n<a class="elsevierStyleCrossRefs" href="#bb0035"><span class="elsevierStyleSup">7&#44;8</span></a>&#46;</p><p id="p0030" class="elsevierStylePara elsevierViewall">Existe en la actualidad una gran variedad de tratamientos para la AGA&#44; pero al d&#237;a de hoy no se dispone de una cura definitiva<a class="elsevierStyleCrossRefs" href="#bb0045"><span class="elsevierStyleSup">9&#44;10</span></a>&#46;</p><p id="p0035" class="elsevierStylePara elsevierViewall">El objetivo de este trabajo es realizar una actualizaci&#243;n de los &#250;ltimos art&#237;culos publicados relativos al tratamiento de la AGA con el fin de determinar la eficacia de las diferentes t&#233;cnicas&#44; as&#237; como de las complicaciones asociadas&#46;</p></span><span id="s0010" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="st0020">Material y m&#233;todos</span><p id="p0040" class="elsevierStylePara elsevierViewall">En esta revisi&#243;n se realiz&#243; una b&#250;squeda en MEDLINE &#40;PubMed&#41; de los estudios publicados en los a&#241;os 2018 y 2019&#46; La revisi&#243;n se actualiz&#243; con fecha de 21 de septiembre de 2019&#46; En la estrategia de b&#250;squeda se utilizaron las siguientes palabras claves&#58; &#40;&#40;&#171;alopecia&#187;&#91;MeSH Terms&#93; OR &#171;alopecia&#187;&#91;All Fields&#93; OR &#171;baldness&#187;&#91;All Fields&#93;&#41; OR &#171;hair loss&#187;&#91;All Fields&#93; AND &#40;&#40;&#171;male&#187;&#91;MeSH Terms&#93; OR &#171;male&#187;&#91;All Fields&#93;&#41; OR &#40;&#171;female&#187;&#91;MeSH Terms&#93; OR &#171;female&#187;&#91;All Fields&#93;&#41; OR &#40;&#171;men&#187;&#91;MeSH Terms&#93; OR &#171;men&#187;&#91;All Fields&#93;&#41; OR &#40;&#171;men&#187;&#91;MeSH Terms&#93; OR &#171;men&#187;&#91;All Fields&#93; OR &#171;man&#187;&#91;All Fields&#93;&#41; OR &#40;&#171;women&#187;&#91;MeSH Terms&#93; OR &#171;women&#187;&#91;All Fields&#93; OR &#171;woman&#187;&#91;All Fields&#93;&#41; OR &#40;&#171;women&#187;&#91;MeSH Terms&#93; OR &#171;women&#187;&#91;All Fields&#93;&#41;&#41; AND androgenetic&#91;All Fields&#93;&#41; OR &#40;androgenetic&#91;All Fields&#93; AND &#40;&#171;alopecia&#187;&#91;MeSH Terms&#93; OR &#171;alopecia&#187;&#91;All Fields&#93;&#41;&#41;&#46;</p><p id="p0045" class="elsevierStylePara elsevierViewall">Para controlar los posibles sesgos&#44; 2 revisores independientes &#40;Alfonso Mogedas Vegara y Eug&#232;nia Agut Busquets&#41; evaluaron los t&#237;tulos y los res&#250;menes de los art&#237;culos&#46; Si no se ten&#237;a la seguridad si el art&#237;culo pod&#237;a cumplir los criterios de inclusi&#243;n&#44; se revis&#243; el art&#237;culo completo&#46; Se excluyeron las opiniones de los expertos&#46; Cuando se identificaron resultados duplicados del mismo estudio&#44; solo se incluyeron los m&#225;s recientes&#46; Se evaluaron los art&#237;culos completos y las diferencias entre ambos revisores se resolvieron mediante discusi&#243;n hasta que se lleg&#243; a un acuerdo&#46;</p><p id="p0050" class="elsevierStylePara elsevierViewall">Los criterios de inclusi&#243;n fueron&#58; a&#41; Estudios con series de pacientes que presentan AGA&#44; y b&#41; Estudios que determinan la eficacia de tratamientos m&#233;dicos o quir&#250;rgicos para el tratamiento de la AGA&#59; y los de exclusi&#243;n&#58; a&#41; Estudios sobre otro tipo de alopecia distinta de la AGA&#44; b&#41; Estudios sobre el tratamiento de la AGA pero que no reflejen la eficacia de las t&#233;cnicas empleadas&#44; c&#41; Revisiones de la literatura&#44; revisiones sistem&#225;ticas y metaan&#225;lisis&#44; d&#41; Estudios duplicados&#44; e&#41; Estudios realizados en animales&#44; f&#41; Estudios experimentales en laboratorio&#44; g&#41; Estudios de cohortes con menos de 10 pacientes&#44; h&#41; Art&#237;culos publicados en otras lenguas distintas al ingl&#233;s&#44; alem&#225;n&#44; franc&#233;s&#44; italiano y espa&#241;ol&#44; i&#41; Cartas y <span class="elsevierStyleItalic">abstracts</span>&#44; j&#41; Encuestas y k&#41; Libros y cap&#237;tulos de libros&#46;</p><p id="p0055" class="elsevierStylePara elsevierViewall">La informaci&#243;n recogida en cada art&#237;culo fue la siguiente&#58; a&#41; Primer autor&#44; b&#41; Tipo de tratamiento o intervenci&#243;n realizada&#44; c&#41; N&#250;mero de pacientes tratados&#44; d&#41; Grado de alopecia masculina &#40;escala de Hamilton-Norwood&#41; o femenina &#40;escala de Ludwig&#41;&#44; e&#41; Tiempo de seguimiento&#46; Herramientas para medir la respuesta&#44; f&#41; Resultados estad&#237;sticamente significativos &#40;p&#8239;&#60;&#8239;0&#44;05&#41; y g&#41; Efectos secundarios o complicaciones&#46;</p></span><span id="s0015" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="st0025">Resultados</span><p id="p0060" class="elsevierStylePara elsevierViewall">La b&#250;squeda inicial en MEDLINE tuvo como resultado 207 art&#237;culos&#46; El estudio inicial de t&#237;tulos y <span class="elsevierStyleItalic">abstracts</span> permiti&#243; eliminar 140 art&#237;culos&#44; dejando 67 art&#237;culos para ser examinados en profundidad&#46; Un total de 31 art&#237;culos cumpl&#237;an los criterios y fueron incluidos para la revisi&#243;n final&#46;</p><p id="p0065" class="elsevierStylePara elsevierViewall">Los art&#237;culos fueron clasificados en 4 grupos&#58; 1&#46;&#41; Medicina oral y t&#243;pica &#40;10 art&#237;culos&#41;&#44; 2&#46;&#41; Medicina regenerativa &#40;plasma rico en plaquetas &#91;PRP&#93; y c&#233;lulas madre&#41; &#40;13 art&#237;culos&#41;&#44; 3&#46;&#41; Aparatolog&#237;a &#40;7 art&#237;culos&#41; y 4&#46;&#41; Trasplante capilar &#40;1 art&#237;culo&#41;&#46;</p><p id="p0070" class="elsevierStylePara elsevierViewall">Los 10 art&#237;culos &#40;32&#44;25&#37;&#41; sobre los tratamientos orales o t&#243;picos para el manejo de la AGA<a class="elsevierStyleCrossRefs" href="#bb0055"><span class="elsevierStyleSup">11&#8211;20</span></a> se resumen en la <a class="elsevierStyleCrossRefs" href="#t0005">tablas 1 y 2</a>&#46; Los 13 art&#237;culos &#40;41&#44;93&#37;&#41; que versaban sobre tratamientos regenerativos con PRP y c&#233;lulas madre se presentan en las <a class="elsevierStyleCrossRefs" href="#t0015">tablas 3 y 4</a> respectivamente<a class="elsevierStyleCrossRefs" href="#bb0105"><span class="elsevierStyleSup">21&#8211;33</span></a>&#46; Los 7 art&#237;culos &#40;22&#44;58&#37;&#41; se incluyeron en el grupo de tratamientos de la AGA mediante aparatolog&#237;a m&#233;dica<a class="elsevierStyleCrossRefs" href="#bb0170"><span class="elsevierStyleSup">34&#8211;40</span></a> y sus resultados se exponen en la <a class="elsevierStyleCrossRef" href="#t0025">tabla 5</a>&#46; Un art&#237;culo &#40;3&#44;22&#37;&#41; estaba relacionado con el trasplante capilar<a class="elsevierStyleCrossRef" href="#bb0205"><span class="elsevierStyleSup">41</span></a> y se muestra en la <a class="elsevierStyleCrossRef" href="#t0030">tabla 6</a>&#46;</p><elsevierMultimedia ident="t0005"></elsevierMultimedia><elsevierMultimedia ident="t0010"></elsevierMultimedia><elsevierMultimedia ident="t0015"></elsevierMultimedia><elsevierMultimedia ident="t0020"></elsevierMultimedia><elsevierMultimedia ident="t0025"></elsevierMultimedia><elsevierMultimedia ident="t0030"></elsevierMultimedia></span><span id="s0020" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="st0030">Discusi&#243;n</span><p id="p0075" class="elsevierStylePara elsevierViewall">En la actualidad los &#250;nicos tratamientos aprobados por la <span class="elsevierStyleItalic">Food and drug administration</span> &#40;FDA&#41; para el tratamiento de la AGA son el minoxidil t&#243;pico &#40;MT&#41;&#44; la finasterida oral &#40;FO&#41; y la terapia con l&#225;ser de baja potencia &#40;LLLT&#41;&#44; siendo la FO&#44; para hombres&#44; y el MT&#44; para hombres y mujeres&#44; los que ofrecen el mayor nivel de evidencia en t&#233;rminos de eficacia y seguridad<a class="elsevierStyleCrossRef" href="#bb0210"><span class="elsevierStyleSup">42</span></a>&#46;</p><p id="p0080" class="elsevierStylePara elsevierViewall">El minoxidil aplicado t&#243;picamente en concentraciones del 2-5&#37; es un f&#225;rmaco aprobado por la FDA para el tratamiento de la AGA de patr&#243;n masculino y femenino&#46; Adem&#225;s&#44; se emplea de forma <span class="elsevierStyleItalic">off-label</span> para el tratamiento de otros tipos de alopecia<a class="elsevierStyleCrossRef" href="#bb0220"><span class="elsevierStyleSup">44</span></a>&#46; Su mecanismo de acci&#243;n no ha sido aclarado&#44; aunque se le atribuye su efecto a un est&#237;mulo sobre la neoangiog&#233;nesis que produce un aumento de la fase an&#225;gena y una disminuci&#243;n de la tel&#243;gena<a class="elsevierStyleCrossRefs" href="#bb0080"><span class="elsevierStyleSup">16&#44;43</span></a>&#46;</p><p id="p0085" class="elsevierStylePara elsevierViewall">La respuesta a la terapia t&#243;pica puede ser lenta y se suelen necesitar de 3 a 6&#8239;meses para objetivar las mejor&#237;as&#46; Cuando cesa el tratamiento&#44; no solo deja de crecer el cabello&#44; sino que se suele producir un efluvio tel&#243;geno de los cabellos dependientes de minoxidil a los 4-6&#8239;meses<a class="elsevierStyleCrossRef" href="#bb0225"><span class="elsevierStyleSup">45</span></a>&#46;</p><p id="p0090" class="elsevierStylePara elsevierViewall">Se ha evaluado la eficacia y la seguridad del MT al 10&#37; en comparaci&#243;n al 5&#37; para el tratamiento de la AGA en hombres&#44; concluyendo que el MT al 5&#37; es moderadamente superior al MT al 10&#37; en el incremento del crecimiento capilar&#44; adem&#225;s de presentar menos efectos secundarios<a class="elsevierStyleCrossRef" href="#bb0090"><span class="elsevierStyleSup">18</span></a>&#46;</p><p id="p0095" class="elsevierStylePara elsevierViewall">La respuesta al MT puede predecirse mediante el test de respuesta a la sulfotransferasa&#44; que es la enzima que se encarga de activar al minoxidil en su forma activa &#40;sulfato de minoxidil&#41;&#46; Debe tenerse en cuenta a los pacientes que toman aspirina&#44; ya que a dosis de 75&#8239;mg puede disminuir la eficacia del MT por inhibir la actividad de la sulfotransferasa<a class="elsevierStyleCrossRef" href="#bb0230"><span class="elsevierStyleSup">46</span></a>&#46; Por el contrario&#44; el tratamiento con retinoides como la tretino&#237;na t&#243;pica es capaz de potenciar la actividad de la sulfotransferasa<a class="elsevierStyleCrossRef" href="#bb0235"><span class="elsevierStyleSup">47</span></a>&#46;</p><p id="p0100" class="elsevierStylePara elsevierViewall">En cuanto al minoxidil administrado por v&#237;a oral &#40;MO&#41; diversos autores han intentado esclarecer su utilidad en el tratamiento de la AGA&#46; En cuanto a las dosis propuestas para los hombres&#44; var&#237;an entre los 0&#44;25&#8239;mg hasta los 5&#8239;mg&#44; presentando un perfil de seguridad similar<a class="elsevierStyleCrossRefs" href="#bb0240"><span class="elsevierStyleSup">48&#44;49</span></a>&#46; Tambi&#233;n se ha estudiado su efecto a dosis de 0&#44;25&#8239;mg al d&#237;a combinado con 25&#8239;mg de espironolactona para el tratamiento de la AGA en las mujeres<a class="elsevierStyleCrossRef" href="#bb0250"><span class="elsevierStyleSup">50</span></a>&#46; Ramos et al&#46; no encuentran diferencias estad&#237;sticamente significativas en la eficacia y el perfil de seguridad cuando comparan en un grupo de 50 mujeres con AGA&#44; el tratamiento con 1&#8239;mg de MO o con MT al 5&#37;<a class="elsevierStyleCrossRef" href="#bb0255"><span class="elsevierStyleSup">51</span></a>&#46;</p><p id="p0105" class="elsevierStylePara elsevierViewall">La finasterida es un antagonista selectivo de los receptores tipo 2 de la 5-alfa-reductasa y est&#225; aprobada por la FDA para el tratamiento de la AGA en hombres&#46; Inhibe la conversi&#243;n de testosterona en dihidrotestosterona&#44; la cual est&#225; relacionada con la miniaturizaci&#243;n del fol&#237;culo&#46; Su uso a largo plazo puede incrementar en un 30&#37; el n&#250;mero de cabellos&#44; pese a asociarse a un 1&#44;5&#37; de riesgo de disfunci&#243;n er&#233;ctil<a class="elsevierStyleCrossRef" href="#bb0260"><span class="elsevierStyleSup">52</span></a>&#46; Los estudios recogidos en la literatura muestran una mejor&#237;a a largo plazo del 93-100&#37; de los pacientes&#44; lo que sugiere que puede ser empleada para prevenir la progresi&#243;n de la AGA en la mayor&#237;a de los casos<a class="elsevierStyleCrossRef" href="#bb0065"><span class="elsevierStyleSup">13</span></a>&#46; Otros autores no encuentran relaci&#243;n entre su uso y la aparici&#243;n de alteraciones sexuales<a class="elsevierStyleCrossRef" href="#bb0265"><span class="elsevierStyleSup">53</span></a>&#46;</p><p id="p0110" class="elsevierStylePara elsevierViewall">En cuanto a su uso en mujeres&#44; no est&#225; aprobada por la FDA ya que se clasifica como un f&#225;rmaco de categor&#237;a X por el riesgo de desarrollar en mujeres en edad f&#233;rtil&#44; alteraciones en los genitales de los fetos masculinos&#46; Por este motivo su uso para el tratamiento de la AGA de patr&#243;n femenino se considera <span class="elsevierStyleItalic">off-label</span> y las mujeres que lo tomen deben de estar informadas sobre el riesgo teratog&#233;nico que implica<a class="elsevierStyleCrossRefs" href="#bb0270"><span class="elsevierStyleSup">54&#44;55</span></a>&#46; Se discute qu&#233; dosis es la m&#225;s eficaz y parece que con 2&#44;5&#8239;mg al d&#237;a se consigue la misma eficacia que con 5&#8239;mg diarios&#44; presentando un perfil de seguridad similar<a class="elsevierStyleCrossRef" href="#bb0070"><span class="elsevierStyleSup">14</span></a>&#46;</p><p id="p0115" class="elsevierStylePara elsevierViewall">La dutasterida es otro antagonista de la 5-alfa-reductasa de tipo 1 y 2 el cual parece presentar mejor eficacia con un perfil de seguridad similar a la finasterida<a class="elsevierStyleCrossRef" href="#bb0280"><span class="elsevierStyleSup">56</span></a>&#46;</p><p id="p0120" class="elsevierStylePara elsevierViewall">En la revisi&#243;n sistem&#225;tica efectuada por Lee et al&#46; se plantea como alternativa el uso t&#243;pico de la finasterida&#44; la cual presenta un perfil de seguridad y resultados preliminares buenos&#44; pero estos deben de ser confirmados con m&#225;s estudios para poder esclarecer su utilidad<a class="elsevierStyleCrossRef" href="#bb0285"><span class="elsevierStyleSup">57</span></a>&#46;</p><p id="p0125" class="elsevierStylePara elsevierViewall">Con el fin de conseguir la m&#225;xima eficacia y satisfacci&#243;n del paciente&#44; encontramos estudios en los que se aplican terapias combinadas por v&#237;a t&#243;pica&#44; oral e inyectable como el de Tanaka et al&#46; sobre 18&#46;918 varones&#44; en el que emplea 1&#8239;mg diario de finasterida por v&#237;a oral&#44; 2&#44;5&#8239;mg de MO y una soluci&#243;n de MT al 5&#37;&#44; ambas administradas 2 veces al d&#237;a junto a inyecciones mensuales sobre el cuero cabelludo de un concentrado variado durante m&#225;s de 6&#8239;meses&#44; obteniendo una mejor&#237;a cl&#237;nica significativa y un grado de satisfacci&#243;n a los 6 y 12&#8239;meses postratamiento del 90 y 86&#37; respectivamente&#46; Sus resultados est&#225;n limitados al no emplear un grupo control y no comparar diferentes dosis<a class="elsevierStyleCrossRef" href="#bb0060"><span class="elsevierStyleSup">12</span></a>&#46;</p><p id="p0130" class="elsevierStylePara elsevierViewall">En cuanto a los tratamientos t&#243;picos para el tratamiento de la AGA se presenta un estudio sobre 67 pacientes tratados con cetirizina&#44; un inhibidor de la prostaglandina D2 &#40;PGD2&#41;&#44; presentando un incremento en la densidad total del cabello&#44; la densidad del cabello terminal y el di&#225;metro&#44; junto con una reducci&#243;n del pelo velloso sin presentar efectos adversos&#46; Se ha relacionado a las prostaglandinas E y F2-&#945; &#40;PGE&#44; PGF2-&#945;&#41; con un papel positivo en el crecimiento capilar&#44; mientras que la PGD2 parece que tiene un efecto inhibitorio del mismo<a class="elsevierStyleCrossRef" href="#bb0100"><span class="elsevierStyleSup">20</span></a>&#46; El latanoprost es un an&#225;logo de la PGF2-&#945; empleado para favorecer el crecimiento de las pesta&#241;as<a class="elsevierStyleCrossRef" href="#bb0290"><span class="elsevierStyleSup">58</span></a>&#46; Se ha presentado un preparado t&#243;pico para el tratamiento de la AGA que presenta un componente que es el &#225;cido dihomo-&#947;-linol&#233;nico el cual se ha visto que puede incrementar los niveles de PDG1 y PGE2<a class="elsevierStyleCrossRef" href="#bb0080"><span class="elsevierStyleSup">16</span></a>&#46;</p><p id="p0135" class="elsevierStylePara elsevierViewall">La cafe&#237;na funciona disminuyendo la actividad local de la fosfodiesterasa e incrementando el aporte de ox&#237;geno al fol&#237;culo&#46; Los champ&#250;s y soluciones con cafe&#237;na se han empleado con m&#237;nimos efectos adversos para el tratamiento de la AGA con resultados prometedores<a class="elsevierStyleCrossRefs" href="#bb0085"><span class="elsevierStyleSup">17&#44;59</span></a>&#46;</p><p id="p0140" class="elsevierStylePara elsevierViewall">La hip&#243;tesis de que los suplementos probi&#243;ticos pueden favorecer el riego sangu&#237;neo del cuero cabelludo y por ello promover el crecimiento capilar ha sido publicada por el grupo de Park et al&#46;<a class="elsevierStyleCrossRef" href="#bb0055"><span class="elsevierStyleSup">11</span></a>&#46;</p><p id="p0145" class="elsevierStylePara elsevierViewall">El mecanismo de acci&#243;n de los champ&#250;s empleados para el tratamiento de la AGA como el CG210&#44; parece relacionado con el incremento del Bcl-2 y del col&#225;geno perifolicular<a class="elsevierStyleCrossRef" href="#bb0095"><span class="elsevierStyleSup">19</span></a>&#44; mientras que otros art&#237;culos lo atribuyen al incremento de c&#233;lulas de Langerhans CD1A<span class="elsevierStyleHsp" style=""></span>&#43;&#44; Ki-67 y Bcl-2<a class="elsevierStyleCrossRef" href="#bb0300"><span class="elsevierStyleSup">60</span></a>&#46;</p><p id="p0150" class="elsevierStylePara elsevierViewall">En cuanto al PRP&#44; la literatura lo define como un procedimiento <span class="elsevierStyleItalic">off-label</span> y m&#237;nimamente invasivo para el tratamiento de la AGA que puede realizarse en la consulta&#46; Es un producto biol&#243;gico constituido por plaquetas aut&#243;logas en un peque&#241;o volumen de plasma y contiene m&#225;s de 20 factores de crecimiento&#46; Los m&#225;s importantes que se han relacionado con el crecimiento capilar son el factor de crecimiento derivado de las plaquetas&#44; el factor de crecimiento transformante beta&#44; el factor de crecimiento vascular endotelial&#44; el factor de crecimiento insul&#237;nico tipo 1 y el factor de crecimiento de fibroblastos &#40;FGF&#41;<a class="elsevierStyleCrossRefs" href="#bb0130"><span class="elsevierStyleSup">26&#8211;28</span></a>&#46;</p><p id="p0155" class="elsevierStylePara elsevierViewall">La mayor&#237;a de los estudios hipotetizan sobre las relaciones que existen entre el crecimiento capilar y los factores de crecimiento que son liberados por las plaquetas&#44; asumiendo que estos inducen la diferenciaci&#243;n de las c&#233;lulas madre&#44; prolongan la supervivencia de las c&#233;lulas de la papila d&#233;rmica y estimulan tanto la neoangiog&#233;nesis como la transici&#243;n de la fase de tel&#243;geno a la de an&#225;geno<a class="elsevierStyleCrossRefs" href="#bb0110"><span class="elsevierStyleSup">22&#8211;24&#44;27&#44;61&#44;62</span></a>&#46;</p><p id="p0160" class="elsevierStylePara elsevierViewall">Existe contradicci&#243;n en cuanto a la relaci&#243;n entre los factores de crecimiento&#44; las plaquetas y la eficacia del PRP&#46; Mientras que algunos autores han relacionado a los pacientes con mayor recuento plaquetario en la preparaci&#243;n de PRP con una mejor respuesta cl&#237;nica en comparaci&#243;n con los pacientes que presentaban un recuento plaquetario menor<a class="elsevierStyleCrossRef" href="#bb0135"><span class="elsevierStyleSup">27</span></a>&#44; otros autores por el contrario no encuentran relaci&#243;n entre la mejor&#237;a cl&#237;nica y los niveles del factor de crecimiento epid&#233;rmico &#40;EGF&#41;&#44; el factor de crecimiento derivado de las plaquetas&#44; el factor de crecimiento vascular endotelial y el n&#250;mero de plaquetas<a class="elsevierStyleCrossRef" href="#bb0105"><span class="elsevierStyleSup">21</span></a>&#46;</p><p id="p0165" class="elsevierStylePara elsevierViewall">Diversos autores han descrito el poder antiinflamatorio y la capacidad de disminuir el sebo del PRP como posibles factores determinantes de su eficacia&#46; Esta &#250;ltima caracter&#237;stica estar&#237;a relacionada con la regulaci&#243;n positiva de la v&#237;a de las Wnt&#47;&#946;-cateninas<a class="elsevierStyleCrossRefs" href="#bb0140"><span class="elsevierStyleSup">28&#44;63</span></a>&#46;</p><p id="p0170" class="elsevierStylePara elsevierViewall">Gentile et al&#46; muestran su experiencia con el sistema de inyecci&#243;n mec&#225;nico para el PRP&#44; empleando una pistola y concluyen que es una t&#233;cnica reproducible&#44; que produce menos dolor en comparaci&#243;n con la t&#233;cnica de inyecci&#243;n manual pero que requiere de cierta experiencia y prolonga la duraci&#243;n del procedimiento<a class="elsevierStyleCrossRef" href="#bb0125"><span class="elsevierStyleSup">25</span></a>&#46;</p><p id="p0175" class="elsevierStylePara elsevierViewall">En la bibliograf&#237;a consultada se relaciona la mejor respuesta al tratamiento con PRP a los pacientes que presentan menor severidad y duraci&#243;n de la AGA<a class="elsevierStyleCrossRefs" href="#bb0120"><span class="elsevierStyleSup">24&#44;28</span></a>&#46; Incluso en estadios avanzados podr&#237;a ser inefectivo<a class="elsevierStyleCrossRef" href="#bb0320"><span class="elsevierStyleSup">64</span></a>&#46; La efectividad del PRP se pone en entredicho en algunos art&#237;culos en los que se equipara la mejor&#237;a con la del grupo que recibi&#243; placebo<a class="elsevierStyleCrossRef" href="#bb0130"><span class="elsevierStyleSup">26</span></a>&#46;</p><p id="p0180" class="elsevierStylePara elsevierViewall">La mayor&#237;a de los estudios de AGA y PRP presentan buena satisfacci&#243;n por parte del paciente y mejoras objetivas en relaci&#243;n al incremento del di&#225;metro y de la densidad capilar<a class="elsevierStyleCrossRefs" href="#bb0325"><span class="elsevierStyleSup">65&#8211;67</span></a>&#46; Es una t&#233;cnica asociada a una baja tasa de complicaciones&#46; Las m&#225;s frecuentes son el dolor y el sangrado leve<a class="elsevierStyleCrossRefs" href="#bb0115"><span class="elsevierStyleSup">23&#44;24&#44;26&#8211;28&#44;30</span></a>&#46; En la revisi&#243;n realizada encontramos que varios art&#237;culos no recogen las complicaciones de los pacientes pudiendo llegar a infravalorarlas<a class="elsevierStyleCrossRefs" href="#bb0105"><span class="elsevierStyleSup">21&#44;22&#44;25</span></a>&#46;</p><p id="p0185" class="elsevierStylePara elsevierViewall">La mayor&#237;a de los art&#237;culos publicados al respecto del tratamiento de la AGA con PRP no son ensayos cl&#237;nicos aleatorizados&#44; tienen tama&#241;os muestrales peque&#241;os&#44; los pacientes presentan diferentes grados de intensidad en la escala de Hamilton-Norwood o Ludwig y encontramos diferentes m&#233;todos de preparaci&#243;n del PRP&#46; Algunos permiten que los pacientes contin&#250;en con su tratamiento habitual para la alopecia y otros no&#46; Los resultados en ocasiones se valoran de forma cuantitativa y en otras de forma cualitativa&#46; La metodolog&#237;a y la composici&#243;n final de los preparados de PRP es inconsistente e insuficiente para comparar los estudios y su eficacia<a class="elsevierStyleCrossRefs" href="#bb0105"><span class="elsevierStyleSup">21&#8211;30&#44;68</span></a>&#46;</p><p id="p0190" class="elsevierStylePara elsevierViewall">Se deber&#237;a establecer un sistema de nomenclatura definido y validado para caracterizar las diferentes composiciones del PRP para as&#237; facilitar la comunicaci&#243;n&#44; la interpretaci&#243;n y la comparaci&#243;n de los resultados&#46; Algunos autores precisan que seg&#250;n la FDA&#44; para poder cuantificar el crecimiento capilar&#44; se deber&#237;a realizar un recuento tricogr&#225;fico&#44; y exponen que actualmente no existen estudios bien elaborados al respecto&#44; con lo que no se puede valorar la eficacia de la t&#233;cnica<a class="elsevierStyleCrossRefs" href="#bb0345"><span class="elsevierStyleSup">69&#44;70</span></a>&#46;</p><p id="p0195" class="elsevierStylePara elsevierViewall">En general&#44; para poder consolidar la utilizaci&#243;n del PRP en el tratamiento de la AGA y determinar su verdadera eficacia&#44; se necesitar&#237;a la realizaci&#243;n de m&#225;s ensayos cl&#237;nicos aleatorizados&#44; mejorar el dise&#241;o de los mismos incluyendo un mayor n&#250;mero de pacientes&#44; realizando determinaciones objetivas con periodos de seguimiento de mayor duraci&#243;n<a class="elsevierStyleCrossRef" href="#bb0105"><span class="elsevierStyleSup">21</span></a>&#46;</p><p id="p0200" class="elsevierStylePara elsevierViewall">Recientemente encontramos estudios sobre el uso de las c&#233;lulas madre para el tratamiento de la AGA&#46; Elmaadawi et al&#46; presentan un estudio en el que infiltran c&#233;lulas mononucleares derivadas de la m&#233;dula &#243;sea a 10 pacientes y c&#233;lulas madre foliculares a otros 10 pacientes&#46; A los 6&#8239;meses los 2 tratamientos produjeron un incremento del di&#225;metro capilar y de la densidad por cm<a class="elsevierStyleCrossRef" href="#bb0010"><span class="elsevierStyleSup">2</span></a> sin diferencias significativas entre ellos&#46; Concluyen que la terapia con c&#233;lulas madre es un tratamiento prometedor&#44; pero todav&#237;a presenta inconvenientes como el precio&#44; el tiempo de procesado&#44; y la necesidad de unas instalaciones espec&#237;ficas con profesionales especializados en su manejo<a class="elsevierStyleCrossRef" href="#bb0160"><span class="elsevierStyleSup">32</span></a>&#46;</p><p id="p0205" class="elsevierStylePara elsevierViewall">Gentile et al&#46; eval&#250;an la efectividad del PRP y los microinjertos con c&#233;lulas madre mesenquimales foliculares en un grupo de 78 pacientes y revisan las v&#237;as biomoleculares implicadas&#46; Concluyen que el incremento de la se&#241;alizaci&#243;n en la v&#237;a de las Wnt en las c&#233;lulas de la papila d&#233;rmica es uno de los principales implicados en el crecimiento capilar&#46; Las c&#233;lulas de la papila d&#233;rmica cuando se cultivan en un medio de crecimiento suplementado con PRP muestran niveles incrementados de Bcl-2 y FGF-7&#44; de prote&#237;nas ERK &#40;quinasas reguladas por se&#241;ales extracelulares&#41; y Akt activadas&#44; y permiten una regulaci&#243;n positiva de las &#946;-catenina&#46; Todo esto se ha relacionado positivamente con el crecimiento y la proliferaci&#243;n capilar<a class="elsevierStyleCrossRef" href="#bb0165"><span class="elsevierStyleSup">33</span></a>&#46;</p><p id="p0210" class="elsevierStylePara elsevierViewall">Se pueden dividir los l&#225;seres que se emplean para el tratamiento de la AGA en fotobiomoduladores o LLLT y en l&#225;seres fraccionales&#46;</p><p id="p0215" class="elsevierStylePara elsevierViewall">Dentro de los fotobiomoduladores encontramos el Hair Max Lasercomb &#174; &#40;aprobado por la FDA&#41;&#44; el l&#225;ser de He-Ne y el l&#225;ser exc&#237;mer&#46; Los LLLT est&#225;n aprobados por la FDA para el tratamiento de la AGA de patr&#243;n masculino y femenino desde 2007 y 2011 respectivamente&#46; Habitualmente emplean una luz roja con longitudes de onda que van de 635 a 678&#8239;nm y contienen entre 51 y 272 l&#225;seres de diodo&#44; con una potencia que var&#237;a de 2 a 20&#8239;mW por diodo&#46; Los protocolos que se recomiendan para su uso var&#237;an entre 10 y 30&#8239;min y de 2 a 7 sesiones semanales<a class="elsevierStyleCrossRef" href="#bb0355"><span class="elsevierStyleSup">71</span></a>&#46; Actualmente se especula que los mecanismos por los que se estimula el crecimiento capilar pueden ser a trav&#233;s de la activaci&#243;n de las Wnt&#47;&#946;-cateninas y la v&#237;a del ERK&#46; El incremento del di&#225;metro capilar podr&#237;a deberse al incremento de la producci&#243;n de adenosina trifosfato&#44; reduciendo la inflamaci&#243;n local y mejorando la vascularizaci&#243;n de la zona<a class="elsevierStyleCrossRef" href="#bb0225"><span class="elsevierStyleSup">45</span></a>&#46; Pachchaprateep et al&#46; realizan un estudio protein&#243;mico para medir la respuesta biol&#243;gica de la papila d&#233;rmica en 4 pacientes afectos de AGA antes y despu&#233;s de ser tratados mediante LLLT&#44; obtienen una mejor&#237;a estad&#237;sticamente significativa en el incremento de cabellos terminales y totales y del &#237;ndice de masa capilar tras 24&#8239;semanas de tratamiento&#44; demostrando el efecto estimulante del LLLT en la papila d&#233;rmica<a class="elsevierStyleCrossRef" href="#bb0360"><span class="elsevierStyleSup">72</span></a>&#46; Los estudios que encontramos en la bibliograf&#237;a concluyen que puede ser un m&#233;todo eficaz para el tratamiento de la AGA tanto en monoterapia como coadyuvante con otros tratamientos&#44; sin encontrar diferencias de efectividad entre hombres y mujeres<a class="elsevierStyleCrossRefs" href="#bb0170"><span class="elsevierStyleSup">34&#44;37</span></a>&#46;</p><p id="p0220" class="elsevierStylePara elsevierViewall">Por otro lado&#44; encontramos los l&#225;seres fraccionales como el l&#225;ser 1550&#8239;nm Erbium-glass &#40;Er-glass&#41;&#44; el l&#225;ser 2940&#8239;nm Erbium&#58;YAG y el l&#225;ser de CO2&#46; Pese a que no se conoce su exacto mecanismo de funcionamiento&#44; se postula que puede ser debido al proceso de cicatrizaci&#243;n tras el trauma inducido y a un incremento en la v&#237;a de las Wnt&#47;&#946;-catenina&#46; Se han empleado como tratamientos eficaces y seguros para varios tipos de alopecia incluyendo la AGA<a class="elsevierStyleCrossRef" href="#bb0365"><span class="elsevierStyleSup">73</span></a>&#46; Los resultados del tratamiento con el l&#225;ser Er-glass y MT al 5&#37; en comparaci&#243;n con MT 5&#37; en monoterapia son superiores en cuanto al incremento de la densidad y del di&#225;metro capilar&#46; Esto puede ser debido a que el l&#225;ser Er-glass favorece el crecimiento capilar y por otro lado facilita la penetraci&#243;n transd&#233;rmica del MT al 5&#37;<a class="elsevierStyleCrossRef" href="#bb0195"><span class="elsevierStyleSup">39</span></a>&#46; Meephansan et al&#46; no encuentran relaci&#243;n tras la utilizaci&#243;n del l&#225;ser de Er-glass para el tratamiento de la AGA en los niveles de IGF-1 y los de Wnt104 mRNA 24&#8239;h despu&#233;s de la irradiaci&#243;n&#44; por lo que debe de haber otros factores relacionados con su efecto sobre el crecimiento capilar<a class="elsevierStyleCrossRef" href="#bb0180"><span class="elsevierStyleSup">36</span></a>&#46; Todav&#237;a encontramos pocos estudios&#44; por lo que ser&#237;a deseable la realizaci&#243;n de ensayos cl&#237;nicos aleatorizados&#44; con mayores tiempos de seguimiento para poder establecer los par&#225;metros &#243;ptimos de tratamiento y sus indicaciones<a class="elsevierStyleCrossRefs" href="#bb0365"><span class="elsevierStyleSup">73&#44;74</span></a>&#46;</p><p id="p0225" class="elsevierStylePara elsevierViewall">La radiofrecuencia fraccionada es otro de los dispositivos basados en la energ&#237;a que se ha empleado para el tratamiento de la AGA&#46; Se postula que su posible mecanismo de acci&#243;n es a trav&#233;s de la activaci&#243;n de FC como el IGF-1 &#40;factor de crecimiento similar a la insulina&#41;&#44; FGF 5 y 7 o a trav&#233;s de la activaci&#243;n de la v&#237;a de las prote&#237;nas Wnt<a class="elsevierStyleCrossRef" href="#bb0190"><span class="elsevierStyleSup">38</span></a>&#46;</p><p id="p0230" class="elsevierStylePara elsevierViewall">El microneedling podr&#237;a ser de utilidad en casos refractarios&#44; presentando escasos efectos secundarios y podr&#237;a facilitar la penetraci&#243;n transd&#233;rmica de diversos f&#225;rmacos<a class="elsevierStyleCrossRef" href="#bb0200"><span class="elsevierStyleSup">40</span></a>&#46;</p><p id="p0235" class="elsevierStylePara elsevierViewall">La carboxiterapia puede ser de utilidad como tratamiento adyuvante de la AGA&#46; En el estudio de Doghaim et al&#46; durante el seguimiento la mayor&#237;a de los pacientes muestran empeoramiento despu&#233;s de suspender las sesiones&#44; aunque estaban mejor que al principio del tratamiento<a class="elsevierStyleCrossRef" href="#bb0175"><span class="elsevierStyleSup">35</span></a>&#46;</p><p id="p0240" class="elsevierStylePara elsevierViewall">El trasplante capilar es la opci&#243;n quir&#250;rgica para el tratamiento de la AGA que se fundamenta en extraer las unidades foliculares de la zona occipital y temporal y colocarlas en aquellas zonas que necesiten una mayor densidad&#46; Es importante realizar una correcta selecci&#243;n de los pacientes candidatos a este tipo de procedimientos&#44; as&#237; como de las unidades foliculares de la zona donante y una t&#233;cnica de disecci&#243;n folicular exquisita&#46; Li KT et al&#46; muestran su experiencia en sesiones de <span class="elsevierStyleItalic">follicular unit extraction</span> de 3000-6000&#8239;unidades foliculares en una muestra de 273 hombres&#44; con unas tasas de supervivencia del 93&#44;5-96&#44;6&#37; y una tasa de satisfacci&#243;n del 81&#37;<a class="elsevierStyleCrossRef" href="#bb0205"><span class="elsevierStyleSup">41</span></a>&#46;</p></span><span id="s0025" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="st0035">Conclusiones</span><p id="p0245" class="elsevierStylePara elsevierViewall">Los &#250;nicos tratamientos aprobados por la FDA para el tratamiento de la AGA son el MT&#44; la FO y los LLLT&#44; siendo la FO&#44; para los hombres&#44; y el MT&#44; para los hombres y las mujeres&#44; los que ofrecen el mayor nivel de evidencia en t&#233;rminos de eficacia y seguridad&#46;</p><p id="p0250" class="elsevierStylePara elsevierViewall">Disponemos en la literatura de otros tratamientos como el PRP&#44; la terapia con c&#233;lulas madre&#44; diversos tratamientos t&#243;picos y orales y diversa aparatolog&#237;a&#46; En su mayor&#237;a parecen ser t&#233;cnicas eficaces y seguras para el tratamiento de la AGA&#44; pero se necesita la realizaci&#243;n de m&#225;s estudios y ensayos cl&#237;nicos aleatorizados con periodos de seguimiento m&#225;s prolongados para poder concluir su eficacia y seguridad&#44; y poder establecer protocolos estandarizados de tratamiento&#46;</p></span><span id="s0030" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="st0040">Financiaci&#243;n</span><p id="p0255" class="elsevierStylePara elsevierViewall">La realizaci&#243;n de este trabajo de fin de m&#225;ster no ha recibido ning&#250;n tipo de financiaci&#243;n&#46;</p></span><span id="s0035" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="st0045">Conflicto de intereses</span><p id="p0260" class="elsevierStylePara elsevierViewall">El autor declara no tener conflicto de intereses&#46;</p></span></span>"
    "textoCompletoSecciones" => array:1 [
      "secciones" => array:8 [
        0 => array:2 [
          "identificador" => "s0005"
          "titulo" => "Introducci&#243;n"
        ]
        1 => array:2 [
          "identificador" => "s0010"
          "titulo" => "Material y m&#233;todos"
        ]
        2 => array:2 [
          "identificador" => "s0015"
          "titulo" => "Resultados"
        ]
        3 => array:2 [
          "identificador" => "s0020"
          "titulo" => "Discusi&#243;n"
        ]
        4 => array:2 [
          "identificador" => "s0025"
          "titulo" => "Conclusiones"
        ]
        5 => array:2 [
          "identificador" => "s0030"
          "titulo" => "Financiaci&#243;n"
        ]
        6 => array:2 [
          "identificador" => "s0035"
          "titulo" => "Conflicto de intereses"
        ]
        7 => array:1 [
          "titulo" => "Bibliograf&#237;a"
        ]
      ]
    ]
    "pdfFichero" => "main.pdf"
    "tienePdf" => true
    "multimedia" => array:6 [
      0 => array:8 [
        "identificador" => "t0005"
        "etiqueta" => "Tabla 1"
        "tipo" => "MULTIMEDIATABLA"
        "mostrarFloat" => true
        "mostrarDisplay" => false
        "detalles" => array:1 [
          0 => array:3 [
            "identificador" => "al0005"
            "detalle" => "Tabla "
            "rol" => "short"
          ]
        ]
        "tabla" => array:2 [
          "leyenda" => "<p id="sp0010" class="elsevierStyleSimplePara elsevierViewall">BASP&#58; basic and specific classification&#59; Ca&#58; casos&#59; Co&#58; controles&#59; H&#58; hombres&#59; HN&#58; Hamilton-Norwood&#59; IGA&#58; investigator&#39;s global assessment&#59; L&#58; Ludwig&#59; M&#58; mujeres&#59; N&#58; n&#250;mero de pacientes&#59; TSS&#58; triple scope system&#59; vo&#58; v&#237;a oral&#59; X&#58; no recogido&#46;</p>"
          "tablatextoimagen" => array:1 [
            0 => array:2 [
              "tabla" => array:1 [
                0 => """
                  <table border="0" frame="\n
                  \t\t\t\t\tvoid\n
                  \t\t\t\t" class=""><thead title="thead"><tr title="table-row"><th class="td" title="\n
                  \t\t\t\t\ttable-head\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t" scope="col" style="border-bottom: 2px solid black">Autor&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t\t\t</th><th class="td" title="\n
                  \t\t\t\t\ttable-head\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t" scope="col" style="border-bottom: 2px solid black">Medicaci&#243;n&#47;intervenci&#243;n&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t\t\t</th><th class="td" title="\n
                  \t\t\t\t\ttable-head\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t" scope="col" style="border-bottom: 2px solid black">Pacientes&#47;escala&#47;seguimiento&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t\t\t</th><th class="td" title="\n
                  \t\t\t\t\ttable-head\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t" scope="col" style="border-bottom: 2px solid black">Evaluaci&#243;n&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t\t\t</th><th class="td" title="\n
                  \t\t\t\t\ttable-head\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t" scope="col" style="border-bottom: 2px solid black">P&#8239;&#60;&#8239;0&#44;05&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t\t\t</th><th class="td" title="\n
                  \t\t\t\t\ttable-head\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t" scope="col" style="border-bottom: 2px solid black">Efectos secundariosn &#40;&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t\t\t</th></tr></thead><tbody title="tbody"><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead rowgroup " rowspan="4" align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Park DW&#44; et al&#46;<a class="elsevierStyleCrossRef" href="#bb0055"><span class="elsevierStyleSup">11</span></a></td><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowgroup " rowspan="4" align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">-Mogut 80&#8239;ml</td><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowgroup " rowspan="2" align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">-n&#8239;&#61;&#8239;46 &#40;23 H&#44; 23 M&#41;</td><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowgroup " rowspan="4" align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">-TSS</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Al 4&#8239;mes&#58;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowgroup " rowspan="4" align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">-No</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowgroup " rowspan="3" align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">-Incremento en el recuento y el grosor</td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">-HN&#58; II-V&#44; L&#58; I-III&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">-4&#8239;meses&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead rowgroup " rowspan="11" align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Tanaka Y&#44; et al&#46;<a class="elsevierStyleCrossRef" href="#bb0060"><span class="elsevierStyleSup">12</span></a></td><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowgroup " rowspan="11" align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">-Finasteride 1&#8239;mg vo&#8239;&#43;&#8239;Minoxidil 2&#44;5&#8239;mg vo y t&#243;pico al 5&#37;&#8239;&#43;&#8239;tratamiento inyectable</td><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowgroup " rowspan="3" align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">-n&#8239;&#61;&#8239;18&#46;918 H-X</td><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowgroup " rowspan="2" align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">-Fotograf&#237;a digital</td><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowgroup " rowspan="11" align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">-X</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">-n&#8239;&#61;&#8239;802 &#40;4&#44;2&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowgroup " rowspan="3" align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">-Dolor leve&#58; n&#8239;&#61;&#8239;651 &#40;3&#44;4&#37;&#41;</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowgroup " rowspan="9" align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">-Autoevaluaci&#243;n</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowgroup " rowspan="7" align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"></td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">-Sangrado leve&#58; n&#8239;&#61;&#8239;56 &#40;0&#44;3&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">-Edema&#58; n&#8239;&#61;&#8239;42 &#40;0&#44;22&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">-Mareos&#58; n&#8239;&#61;&#8239;28 &#40;0&#44;15&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">-Picor&#58; n&#8239;&#61;&#8239;7 &#40;0&#44;04&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">-Eritema&#58; n&#8239;&#61;&#8239;4 &#40;0&#44;02&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowgroup " rowspan="2" align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">-Disfunci&#243;n er&#233;ctil&#58; n&#8239;&#61;&#8239;14 &#40;0&#44;07&#37;&#41;</td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">-M&#237;nimo 18&#8239;meses&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead rowgroup " rowspan="9" align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Shin JW&#44; et al&#46;<a class="elsevierStyleCrossRef" href="#bb0065"><span class="elsevierStyleSup">13</span></a></td><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowgroup " rowspan="9" align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">-Finasteride 1&#8239;mg vo</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">-n&#8239;&#61;&#8239;126 H&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowgroup " rowspan="2" align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">-Fotograf&#237;as</td><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowgroup " rowspan="5" align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">IGA score despu&#233;s de 6&#8239;meses&#44; 1 y 2&#8239;a&#241;os&#58;-Tipo V presenta m&#225;s mejora que F y el tipo b&#225;sico</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">-n&#8239;&#61;&#8239;12 &#40;9&#44;5&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowgroup " rowspan="2" align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">-BASP</td><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowgroup " rowspan="3" align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">-Disminuci&#243;n libido&#58; n&#8239;&#61;&#8239;4 &#40;3&#44;1&#37;&#41;</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowgroup " rowspan="7" align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">-Evaluaci&#243;n dermat&#243;logos</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowgroup " rowspan="6" align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">-5&#8239;a&#241;os</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowgroup " rowspan="2" align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">-Disminuci&#243;n semen&#58; n&#8239;&#61;&#8239;3 &#40;2&#44;4&#37;&#41;</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowgroup " rowspan="4" align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"></td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">-Disfunci&#243;n er&#233;ctil&#58; n&#8239;&#61;&#8239;3 &#40;2&#44;4&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">-Disfunci&#243;n hep&#225;tica&#58; n&#8239;&#61;&#8239;1 &#40;0&#44;8&#37;&#41;&#44;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Problemas gastrointestinales&#58; n&#8239;&#61;&#8239;1 &#40;0&#44;8&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead rowgroup " rowspan="5" align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Won YY&#44; et al&#46;<a class="elsevierStyleCrossRef" href="#bb0070"><span class="elsevierStyleSup">14</span></a></td><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowgroup " rowspan="5" align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">-Finasteride 2&#44;5&#8239;mg vo</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">-n&#8239;&#61;&#8239;112 M&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowgroup " rowspan="2" align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">-Fotograf&#237;as-Escala</td><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowgroup " rowspan="3" align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">-Asociaci&#243;n negativa entre la duraci&#243;n y la mejor&#237;a</td><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowgroup " rowspan="5" align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">-No</td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">-L&#58; I-III&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowgroup " rowspan="3" align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">-17&#44;6&#8239;&#177;&#8239;12&#44;9&#8239;meses</td><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowgroup " rowspan="3" align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"></td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">-Asociaci&#243;n positiva entre la edad de aparici&#243;n&#44; la duraci&#243;n del tratamiento y la mejor&#237;a del scalp&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">-A menor Ludwig&#44; mayor crecimiento capilar&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr></tbody></table>
                  """
              ]
              "imagenFichero" => array:1 [
                0 => "xTab2618528.png"
              ]
            ]
          ]
        ]
        "descripcion" => array:1 [
          "es" => "<p id="sp0005" class="elsevierStyleSimplePara elsevierViewall">Art&#237;culos seleccionados de tratamiento oral de la alopecia androg&#233;nica</p>"
        ]
      ]
      1 => array:8 [
        "identificador" => "t0010"
        "etiqueta" => "Tabla 2"
        "tipo" => "MULTIMEDIATABLA"
        "mostrarFloat" => true
        "mostrarDisplay" => false
        "detalles" => array:1 [
          0 => array:3 [
            "identificador" => "al0010"
            "detalle" => "Tabla "
            "rol" => "short"
          ]
        ]
        "tabla" => array:2 [
          "leyenda" => "<p id="sp0020" class="elsevierStyleSimplePara elsevierViewall">Ca&#58; casos&#59; Co&#58; controles&#59; DLQI&#58; quality of life evaluation&#59; H&#58; hombres&#59; HN&#58; Hamilton-Norwood&#59; L&#58; Ludwig&#59; M&#58; mujeres&#59; MT&#58; minoxidil t&#243;pico&#59; N&#58; n&#250;mero de pacientes&#59; X&#58; no recogido&#46;</p>"
          "tablatextoimagen" => array:1 [
            0 => array:2 [
              "tabla" => array:1 [
                0 => """
                  <table border="0" frame="\n
                  \t\t\t\t\tvoid\n
                  \t\t\t\t" class=""><thead title="thead"><tr title="table-row"><th class="td" title="\n
                  \t\t\t\t\ttable-head\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t" scope="col" style="border-bottom: 2px solid black">Autor&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t\t\t</th><th class="td" title="\n
                  \t\t\t\t\ttable-head\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t" scope="col" style="border-bottom: 2px solid black">Medicaci&#243;n&#47;intervenci&#243;n&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t\t\t</th><th class="td" title="\n
                  \t\t\t\t\ttable-head\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t" scope="col" style="border-bottom: 2px solid black">Pacientes&#47;escala&#47;seguimiento&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t\t\t</th><th class="td" title="\n
                  \t\t\t\t\ttable-head\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t" scope="col" style="border-bottom: 2px solid black">Evaluaci&#243;n&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t\t\t</th><th class="td" title="\n
                  \t\t\t\t\ttable-head\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t" scope="col" style="border-bottom: 2px solid black">P&#8239;&#60;&#8239;0&#44;05&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t\t\t</th><th class="td" title="\n
                  \t\t\t\t\ttable-head\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t" scope="col" style="border-bottom: 2px solid black">Efectos secundariosn &#40;&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t\t\t</th></tr></thead><tbody title="tbody"><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead rowgroup " rowspan="8" align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Blume-Peytavi U&#44; et al&#46;<a class="elsevierStyleCrossRef" href="#bb0075"><span class="elsevierStyleSup">15</span></a></td><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowgroup " rowspan="6" align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">-Minoxidil 5&#37;DC0120 vs&#46; Alostil&#174;</td><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowgroup " rowspan="4" align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">-220 H-HN&#58; III-V-16&#8239;semanas</td><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowgroup " rowspan="3" align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">-Fototricograma &#40;TrichoScan&#174;&#41;</td><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowgroup " rowspan="8" align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">-Mismo perfil de eficacia y seguridad</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">-Prurito&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">-Eritema&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowgroup " rowspan="6" align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">-Sensaci&#243;n de quemaz&#243;n-Descamaci&#243;n</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowgroup " rowspan="2" align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">-Fotograf&#237;a digital</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowgroup " rowspan="2" align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"></td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowgroup " rowspan="2" align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">-Frecuencia card&#237;aca</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowgroup " rowspan="2" align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"></td><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowgroup " rowspan="2" align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"></td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">-Tensi&#243;n arterial&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead rowgroup " rowspan="8" align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Brotzu G&#44; et al&#46;<a class="elsevierStyleCrossRef" href="#bb0080"><span class="elsevierStyleSup">16</span></a></td><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowgroup " rowspan="8" align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">-Trinov 1&#8239;ml</td><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowgroup " rowspan="2" align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">-n&#8239;&#61;&#8239;69 &#40;30 H&#44; -29 M&#41;</td><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowgroup " rowspan="3" align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">-Fototricograma &#40;Fotofinder-Trichoscan&#41;</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">A los 6&#8239;meses&#58;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowgroup " rowspan="8" align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">-Sensaci&#243;n de quemaz&#243;n leve&#58; n&#8239;&#61;&#8239;1</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowgroup " rowspan="2" align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">-Incremento an&#225;geno&#47;tel&#243;geno</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowgroup " rowspan="3" align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">-HN&#58; II-IV&#44; L&#58; I-II-6&#8239;meses</td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">-Pull test&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowgroup " rowspan="5" align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">-Mejor&#237;a pull test y wash test</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowgroup " rowspan="2" align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">-Microscopia electr&#243;nica</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowgroup " rowspan="3" align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"></td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">-Encuesta pacientes&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">-Valoraci&#243;n dermat&#243;logo&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead rowgroup " rowspan="6" align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Bussoletti C&#44; et al&#46;<a class="elsevierStyleCrossRef" href="#bb0085"><span class="elsevierStyleSup">17</span></a></td><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowgroup " rowspan="6" align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">-Champ&#250; &#40;B70011&#41; &#40;con cafe&#237;na&#41; vs&#46; Champ&#250; &#40;B70012&#41;</td><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowgroup " rowspan="3" align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">-n&#8239;&#61;&#8239;140 M &#40;70 Ca&#44; 70 Co&#41;</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">-Pull test&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowgroup " rowspan="2" align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">-Mejor&#237;a pull test</td><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowgroup " rowspan="6" align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">-No</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowgroup " rowspan="5" align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">-Comentarios investigadores y pacientes</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowgroup " rowspan="3" align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">-Incremento grosor&#44; disminuci&#243;n eritema</td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">-L&#58; I-III&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowgroup " rowspan="2" align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">-6&#8239;meses</td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">-Pacientes satisfechos&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead rowgroup " rowspan="13" align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Ghonemy S&#44; et al&#46;<a class="elsevierStyleCrossRef" href="#bb0090"><span class="elsevierStyleSup">18</span></a></td><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowgroup " rowspan="3" align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">-Minoxidil 10&#37; vs&#46;minoxidil 5&#37; vs&#46; placebo</td><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowgroup " rowspan="5" align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">-n&#8239;&#61;&#8239;63 H &#40;n&#8239;&#61;&#8239;27 MT5&#37;&#44; n&#8239;&#61;&#8239;24 MT10&#37;&#44; n&#8239;&#61;&#8239;12 placebo&#41;</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">-Pull test&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">A favor MT5&#37;&#58;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowgroup " rowspan="2" align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">MT 10&#37; vs&#46; MT 5&#37;</td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">-Fotograf&#237;as&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowgroup " rowspan="6" align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">-Mayor recuento total de pelos terminales en el v&#233;rtex pero inferior de intermedios en comparaci&#243;n al 10&#37;</td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">-Tricoscopio&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowgroup " rowspan="2" align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">-Dermatitis de contacto 100&#37; vs&#46; 22&#44;2&#37;</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowgroup " rowspan="10" align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"></td><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowgroup " rowspan="10" align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">-Escala de satisfacci&#243;n</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowgroup " rowspan="4" align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">-Erosiones 25&#37; vs&#46; 11&#44;1&#37;</td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">-HN&#58; III-VII&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowgroup " rowspan="7" align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">-36&#8239;semanas</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowgroup " rowspan="2" align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">-Mayor grosor en v&#233;rtex</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowgroup " rowspan="3" align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">-Hipertricosis 9 pacientes vs&#46; 6 pacientes</td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">-Mayor n&#250;mero UF de un cabello y de 3 cabellos en v&#233;rtex&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowgroup " rowspan="3" align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">-Mayor n&#250;mero de UF de 2 cabellos en zona frontal</td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">-Cefalea 25&#37; vs&#46; 11&#44;1&#37;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">-Ca&#237;da cabello al inicio 100&#37; vs 55&#37;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead rowgroup " rowspan="6" align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Katoulis AC&#44; et al&#46;<a class="elsevierStyleCrossRef" href="#bb0095"><span class="elsevierStyleSup">19</span></a></td><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowgroup " rowspan="6" align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">-CG210&#174; vs&#46; placebo</td><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowgroup " rowspan="3" align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">-n&#8239;&#61;&#8239;39 M &#40;26 Ca&#44; 13 Co&#41;</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">-Examen cl&#237;nico&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">A los 6&#8239;meses&#58;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowgroup " rowspan="6" align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">-No</td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">-Fotograf&#237;as&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowgroup " rowspan="5" align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">-Incremento ratio an&#225;geno&#47;tel&#243;geno&#44; mejor DLQI y percepci&#243;n personal</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowgroup " rowspan="2" align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">-Evaluaci&#243;n DLQI</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowgroup " rowspan="2" align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">-L&#58; I-III</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowgroup " rowspan="2" align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">-Tricograma</td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">-24&#8239;semanas&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead rowgroup " rowspan="3" align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Rossi A&#44; et al&#46;<a class="elsevierStyleCrossRef" href="#bb0100"><span class="elsevierStyleSup">20</span></a></td><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowgroup " rowspan="3" align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">-Cetirizina 1&#37; vs&#46; placebo</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">-n&#8239;&#61;&#8239;85 &#40;67 Ca&#44; 18 Co&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowgroup " rowspan="2" align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">-Fotograf&#237;as &#40;Trichoscon Dermoscope Fotofinder&#174;&#41;</td><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowgroup " rowspan="3" align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">-X</td><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowgroup " rowspan="3" align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">-No</td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">-X&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">-6&#8239;meses&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">-Evaluaci&#243;n por dermat&#243;logos&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr></tbody></table>
                  """
              ]
              "imagenFichero" => array:1 [
                0 => "xTab2618531.png"
              ]
            ]
          ]
        ]
        "descripcion" => array:1 [
          "es" => "<p id="sp0015" class="elsevierStyleSimplePara elsevierViewall">Art&#237;culos seleccionados de tratamiento t&#243;pico de la alopecia androg&#233;nica</p>"
        ]
      ]
      2 => array:8 [
        "identificador" => "t0015"
        "etiqueta" => "Tabla 3"
        "tipo" => "MULTIMEDIATABLA"
        "mostrarFloat" => true
        "mostrarDisplay" => false
        "detalles" => array:1 [
          0 => array:3 [
            "identificador" => "al0015"
            "detalle" => "Tabla "
            "rol" => "short"
          ]
        ]
        "tabla" => array:2 [
          "leyenda" => "<p id="sp0030" class="elsevierStyleSimplePara elsevierViewall">A-PRP&#58; plasma rico en plaquetas aut&#243;geno no activado&#59; Ca&#58; casos&#59; Co&#58; controles&#59; H&#58; hombres&#59; HN&#58; Hamilton-Norwood&#59; L&#58; Ludwig&#59; M&#58; mujeres&#59; MT&#58; minoxidil t&#243;pico&#59; N&#58; n&#250;mero de pacientes&#59; PRP&#58; plasma rico en plaquetas&#59; X&#58; no recogido&#46;</p>"
          "tablatextoimagen" => array:1 [
            0 => array:2 [
              "tabla" => array:1 [
                0 => """
                  <table border="0" frame="\n
                  \t\t\t\t\tvoid\n
                  \t\t\t\t" class=""><thead title="thead"><tr title="table-row"><th class="td" title="\n
                  \t\t\t\t\ttable-head\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t" scope="col" style="border-bottom: 2px solid black">Autor&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t\t\t</th><th class="td" title="\n
                  \t\t\t\t\ttable-head\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t" scope="col" style="border-bottom: 2px solid black">Modelo PRP&#47;intervenci&#243;n&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t\t\t</th><th class="td" title="\n
                  \t\t\t\t\ttable-head\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t" scope="col" style="border-bottom: 2px solid black">Pacientes&#47;escalas&#47; seguimiento&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t\t\t</th><th class="td" title="\n
                  \t\t\t\t\ttable-head\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t" scope="col" style="border-bottom: 2px solid black">Evaluaci&#243;n&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t\t\t</th><th class="td" title="\n
                  \t\t\t\t\ttable-head\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t" scope="col" style="border-bottom: 2px solid black">P&#8239;&#60;&#8239;0&#46;05&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t\t\t</th><th class="td" title="\n
                  \t\t\t\t\ttable-head\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t" scope="col" style="border-bottom: 2px solid black">Efectos secundarios n &#40;&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t\t\t</th></tr></thead><tbody title="tbody"><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead rowgroup " rowspan="4" align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Rodrigues B&#44; et al&#46;<a class="elsevierStyleCrossRef" href="#bb0105"><span class="elsevierStyleSup">21</span></a></td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">-X&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowgroup " rowspan="2" align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">-n&#8239;&#61;&#8239;26 H &#40;15 Ca&#44; 11 Co&#41;</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">-TrichoScan&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowgroup " rowspan="4" align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">-Incremento en el recuento y densidad de cabellos y en el &#37; de pelos en an&#225;geno a los 3&#8239;meses de la &#250;ltima inyecci&#243;n</td><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowgroup " rowspan="4" align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">-X</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowgroup " rowspan="3" align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">-PRP vs&#46; suero</td><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowgroup " rowspan="3" align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">-Siemens Advia2120 I &#40;t&#233;cnica Luminex&#41;</td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">-HN III v&#233;rtex&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">-3&#8239;meses&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead rowgroup " rowspan="8" align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Butt G&#44; et al&#46;<a class="elsevierStyleCrossRef" href="#bb0110"><span class="elsevierStyleSup">22</span></a></td><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowgroup " rowspan="3" align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">-Tray Life Tube Gel</td><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowgroup " rowspan="4" align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">-n&#8239;&#61;&#8239;30 &#40;20 H&#44; 10 M&#41;</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">-Fotograf&#237;as&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowgroup " rowspan="2" align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">A los 6&#8239;meses&#58;</td><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowgroup " rowspan="8" align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">-X</td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">-Pull test&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowgroup " rowspan="3" align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">-Tricoscopic Photomicrographs</td><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowgroup " rowspan="5" align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">-Mejor&#237;a en el pull test&#44; evaluaci&#243;n m&#233;dica y satisfacci&#243;n del paciente</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowgroup " rowspan="5" align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">-PRP</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowgroup " rowspan="2" align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">-HN&#58; II&#44; IV&#44; VI&#44; L&#58; I-III</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowgroup " rowspan="3" align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">-Evaluaci&#243;n m&#233;dica y escala de satisfacci&#243;n del paciente</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowgroup " rowspan="2" align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">-6&#8239;meses</td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">-Aumento de la densidad capilar&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead rowgroup " rowspan="5" align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Schiavone G&#44; et al&#46;<a class="elsevierStyleCrossRef" href="#bb0115"><span class="elsevierStyleSup">23</span></a></td><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowgroup " rowspan="2" align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">-GLO PRP blood separation kit</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">-n&#8239;&#61;&#8239;168 &#40;102 H&#44; 66 M&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowgroup " rowspan="5" align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">-Fotograf&#237;as evaluadas por expertos</td><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowgroup " rowspan="5" align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">-Mejor&#237;a cl&#237;nica con respecto al grupo control</td><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowgroup " rowspan="5" align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">-Hematomas</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowgroup " rowspan="2" align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">&#40;139 Ca&#44; 29 Co&#41;</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowgroup " rowspan="3" align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">-iL-PRF vs&#46; nada</td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">-HN&#58; II-V&#44; L&#58; I-II&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">-X&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead rowgroup " rowspan="12" align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Hausauer A&#44; et al&#46;<a class="elsevierStyleCrossRef" href="#bb0120"><span class="elsevierStyleSup">24</span></a></td><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowgroup " rowspan="2" align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">-Eclipse PRP kit</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">-n&#8239;&#61;&#8239;39&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">-Folioscopio&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowgroup " rowspan="5" align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">A los 6&#8239;meses en ambos grupos&#58;</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">-n&#8239;&#61;&#8239;39&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowgroup " rowspan="2" align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">PRP 1&#58; 20 &#40;17 H&#44; 3 M&#41;</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">-Fotograf&#237;as&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowgroup " rowspan="3" align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">-Dolor&#47;molestias&#58;</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowgroup " rowspan="10" align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">-PRP 1 vs&#46; PRP 2</td><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowgroup " rowspan="10" align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">-Encuestas de satisfacci&#243;n</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowgroup " rowspan="6" align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">PRP 2&#58; 19 &#40;12 H&#44; 7 M&#41;</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowgroup " rowspan="2" align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">n&#8239;&#61;&#8239;12 &#40;30&#44;7&#37;&#41;</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowgroup " rowspan="5" align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">-Mejor&#237;a en el recuento capilar &#40;m&#225;s r&#225;pido y cl&#237;nicamente relevante en el grupo 1&#41;</td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">-Cefalea&#58; n&#8239;&#61;&#8239;5 &#40;12&#44;8&#37;&#41;&#44;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">-Picor&#58; n&#8239;&#61;&#8239;8&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowgroup " rowspan="4" align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">&#40;15&#44;4&#37;&#41;</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowgroup " rowspan="2" align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">-HN&#58; II-V&#44; L&#58; I2-II1</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowgroup " rowspan="2" align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">-Mejor&#237;a en el calibre</td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">-6&#8239;meses&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead rowgroup " rowspan="4" align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Gentile P&#44; et al&#46;<a class="elsevierStyleCrossRef" href="#bb0125"><span class="elsevierStyleSup">25</span></a></td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">-X&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowgroup " rowspan="2" align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">-n&#8239;&#61;&#8239;23 &#40;18 H&#44; 5 M&#41;</td><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowgroup " rowspan="4" align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">-Tricoscopio</td><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowgroup " rowspan="4" align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">-X</td><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowgroup " rowspan="4" align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">-X</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowgroup " rowspan="3" align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">-A-PRP vs&#46; suero</td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">-HN&#58; II-V&#44;L&#58; I-II&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">-5&#8239;meses&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead rowgroup " rowspan="6" align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Dicle &#214;&#44; et al&#46;<a class="elsevierStyleCrossRef" href="#bb0130"><span class="elsevierStyleSup">26</span></a></td><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowgroup " rowspan="2" align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">-Genesis PRP kit</td><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowgroup " rowspan="4" align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">-n&#8239;&#61;&#8239;25 H &#40;10 Ca&#44; 15 Co&#41;</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">-TrichoScan&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowgroup " rowspan="6" align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">-Recuento capilar total superior en el grupo placebo cuando se compar&#243; M4 vs M9 y M0 vs M9</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">-Dolor local&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowgroup " rowspan="2" align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">-2 dermat&#243;logos</td><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowgroup " rowspan="5" align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">-Edema transitorio</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowgroup " rowspan="4" align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">-PRP vs&#46; placebo</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowgroup " rowspan="3" align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">-Recuento manual con el software ImageJ</td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">-HN&#58; IIIv-V&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">-4&#8239;meses&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead rowgroup " rowspan="8" align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Verma K&#44; et al&#46;<a class="elsevierStyleCrossRef" href="#bb0135"><span class="elsevierStyleSup">27</span></a></td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">-X&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">-n&#8239;&#61;&#8239;30 H&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">-Fotograf&#237;as&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowgroup " rowspan="4" align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">A los 6&#8239;meses a favor del PRP&#58;</td><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowgroup " rowspan="8" align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">-Dolor&#58; 4 pacientes del grupo del PRP dejan el estudio por el dolor provocado por las inyecciones</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowgroup " rowspan="7" align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">-PRP vs&#46; MT 5&#37;</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">-PRP&#58; 16&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">-Pull Test&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">-MT5&#37;&#58; 14&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowgroup " rowspan="3" align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">-Cuestionario de crecimiento capilar</td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">-HN&#58; II-V&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowgroup " rowspan="4" align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">-6&#8239;meses</td><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowgroup " rowspan="3" align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">-Mejor&#237;a en 2 preguntas del cuestionario de crecimiento capilar</td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">-Encuesta de satisfacci&#243;n&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowgroup " rowspan="2" align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">-Recuento plaquetario en el PRP</td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">-Mejores resultados en la encuesta de satisfacci&#243;n&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead rowgroup " rowspan="8" align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Qu Q&#44; et al&#46;<a class="elsevierStyleCrossRef" href="#bb0140"><span class="elsevierStyleSup">28</span></a></td><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowgroup " rowspan="3" align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">-Tricell kit</td><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowgroup " rowspan="4" align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">-n&#8239;&#61;&#8239;93 &#40;51 H&#44; 42 M&#41;</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">-Pull test&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowgroup " rowspan="2" align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">A los 6&#8239;meses&#58;</td><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowgroup " rowspan="2" align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">-n&#8239;&#61;&#8239;53 &#40;30 H&#44; 23 M&#41;</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowgroup " rowspan="3" align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">-Fototricograma</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowgroup " rowspan="3" align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">-Incremento de grosor y densidad</td><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowgroup " rowspan="4" align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">-Dolor leve&#44; picor leve&#58; n&#8239;&#61;&#8239;2 &#40;H&#41;</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowgroup " rowspan="5" align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">-PRP</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowgroup " rowspan="3" align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">-HN&#58; II-V&#44; L&#58; I-III</td><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowgroup " rowspan="2" align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">-Fotograf&#237;as</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowgroup " rowspan="3" align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">-Mejor&#237;a en la inflamaci&#243;n del scalp&#44; la secreci&#243;n grasa y el hair-pull test</td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">-Cuestionarios de satisfacci&#243;n&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">-Cefalea&#58; n&#8239;&#61;&#8239;1 &#40;M&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">-6&#8239;meses&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">-TrichoScan&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">-Sensaci&#243;n de lagrimeo&#58; n&#8239;&#61;&#8239;1 &#40;M&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead rowgroup " rowspan="4" align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Starace M&#44; et al&#46;<a class="elsevierStyleCrossRef" href="#bb0145"><span class="elsevierStyleSup">29</span></a></td><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowgroup " rowspan="3" align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">-My Cells &#174;system</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">-n&#8239;&#61;&#8239;10 M&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">-Pull test&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowgroup " rowspan="2" align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">A las 12 y 24&#8239;semanas&#58;</td><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowgroup " rowspan="4" align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">-No efectos adversos severos registrados</td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">-L&#58; I-III&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">-Fotograf&#237;as&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowgroup " rowspan="2" align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">-24&#8239;semanas</td><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowgroup " rowspan="2" align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">-Trichoscan &#40;FotoFinder dermatoscope&#174;&#41;</td><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowgroup " rowspan="2" align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">-Incremento del di&#225;metro en la zona frontal</td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">-PRP&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead rowgroup " rowspan="4" align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Bayat M&#44; et al&#46;<a class="elsevierStyleCrossRef" href="#bb0150"><span class="elsevierStyleSup">30</span></a></td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">-X&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">-n&#8239;&#61;&#8239;19 H&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowgroup " rowspan="3" align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">-Fotograf&#237;a digital y dermatosc&#243;pica</td><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowgroup " rowspan="4" align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">-Incremento del grosor capilar despu&#233;s de la primera inyecci&#243;n en comparaci&#243;n con el resto</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">-Dolor leve y localizado&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowgroup " rowspan="3" align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">-PRP</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">-HN&#58; IIIv-V&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowgroup " rowspan="3" align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">-Sangrado leve</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowgroup " rowspan="2" align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">-5&#8239;meses</td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">-Evaluaci&#243;n por dermat&#243;logos&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead rowgroup " rowspan="6" align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Jha AK&#44; et al&#46;<a class="elsevierStyleCrossRef" href="#bb0155"><span class="elsevierStyleSup">31</span></a></td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">-X&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">-n&#8239;&#61;&#8239;93 H&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">-Fotograf&#237;as&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowgroup " rowspan="2" align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">A los 3&#8239;meses&#58;</td><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowgroup " rowspan="6" align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">-Dolor transitorio en B&#41; y C&#41;</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowgroup " rowspan="2" align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">-A&#41; MT5&#37; vs&#46;</td><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowgroup " rowspan="3" align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">-A &#40;n&#8239;&#61;&#8239;31&#44; B n<span class="elsevierStyleHsp" style=""></span>&#61; 31&#44; C n<span class="elsevierStyleHsp" style=""></span>&#61; 31&#41;</td><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowgroup " rowspan="2" align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">-Dermatoscopio</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowgroup " rowspan="4" align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">-Mejores resultados en C&#41; en&#58; hair pull test&#44; ratio terminal&#47;velloso y escala de satisfacci&#243;n</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowgroup " rowspan="2" align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">B&#41; MT5&#37; &#43; PRP vs&#46;</td><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowgroup " rowspan="2" align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">-Hair pull test</td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">-HN&#58; I-V&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">C&#41; PRP &#43; microneedling&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">-3&#8239;meses&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">-Escala de satisfacci&#243;n&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr></tbody></table>
                  """
              ]
              "imagenFichero" => array:1 [
                0 => "xTab2618527.png"
              ]
            ]
          ]
        ]
        "descripcion" => array:1 [
          "es" => "<p id="sp0025" class="elsevierStyleSimplePara elsevierViewall">Art&#237;culos seleccionados de tratamiento de la alopecia androg&#233;nica con plasma rico en plaquetas</p>"
        ]
      ]
      3 => array:8 [
        "identificador" => "t0020"
        "etiqueta" => "Tabla 4"
        "tipo" => "MULTIMEDIATABLA"
        "mostrarFloat" => true
        "mostrarDisplay" => false
        "detalles" => array:1 [
          0 => array:3 [
            "identificador" => "al0020"
            "detalle" => "Tabla "
            "rol" => "short"
          ]
        ]
        "tabla" => array:2 [
          "leyenda" => "<p id="sp0040" class="elsevierStyleSimplePara elsevierViewall">A-PRP&#58; plasma rico en plaquetas aut&#243;geno no activado&#59; BMMC&#58; c&#233;lulas mononucleares derivadas de la m&#233;dula &#243;sea&#59; FSC&#58; c&#233;lulas madre foliculares&#59; H&#58; hombres&#59; HF-MSC&#58; microinjertos que contienen c&#233;lulas madre mesenquimales del fol&#237;culo humano&#59; HN&#58; Hamilton-Norwood&#59; L&#58; Ludwig&#59; LLLT&#58; l&#225;ser de baja potencia&#59; M&#58; mujeres&#59; N&#58; n&#250;mero de pacientes&#59; X&#58; no recogido&#46;</p>"
          "tablatextoimagen" => array:1 [
            0 => array:2 [
              "tabla" => array:1 [
                0 => """
                  <table border="0" frame="\n
                  \t\t\t\t\tvoid\n
                  \t\t\t\t" class=""><thead title="thead"><tr title="table-row"><th class="td" title="\n
                  \t\t\t\t\ttable-head\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t" scope="col" style="border-bottom: 2px solid black">Autor&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t\t\t</th><th class="td" title="\n
                  \t\t\t\t\ttable-head\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t" scope="col" style="border-bottom: 2px solid black">Intervenci&#243;n&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t\t\t</th><th class="td" title="\n
                  \t\t\t\t\ttable-head\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t" scope="col" style="border-bottom: 2px solid black">Pacientes&#47;escalas&#47; seguimiento&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t\t\t</th><th class="td" title="\n
                  \t\t\t\t\ttable-head\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t" scope="col" style="border-bottom: 2px solid black">Evaluaci&#243;n&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t\t\t</th><th class="td" title="\n
                  \t\t\t\t\ttable-head\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t" scope="col" style="border-bottom: 2px solid black">P&#8239;&#60;&#8239;0&#44;05&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t\t\t</th><th class="td" title="\n
                  \t\t\t\t\ttable-head\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t" scope="col" style="border-bottom: 2px solid black">Efectos secundarios &#40;n&#47;&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t\t\t</th></tr></thead><tbody title="tbody"><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead rowgroup " rowspan="10" align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Elmaadawi IH&#44; et al&#46;<a class="elsevierStyleCrossRef" href="#bb0160"><span class="elsevierStyleSup">32</span></a></td><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowgroup " rowspan="10" align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">-BMMC vs&#46; FSC</td><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowgroup " rowspan="4" align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">-n&#8239;&#61;&#8239;20 &#40;10&#8239;&#61;&#8239;BMMC &#91;3 H&#44; 7 M&#93; 10 FSC &#91;5 H&#44; 5 M&#93;&#41;</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">-Fotograf&#237;as&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowgroup " rowspan="2" align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">A los 6&#8239;meses&#58;</td><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowgroup " rowspan="6" align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">-Fatiga inducida por el factor estimulante de colonias de granulocitos</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowgroup " rowspan="2" align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">-Estudio histopatol&#243;gico</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowgroup " rowspan="8" align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">-Incremento del di&#225;metro capilar y de la densidad por cm<span class="elsevierStyleSup">2</span> en ambos grupos sin diferencias significativas entre ellos</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowgroup " rowspan="2" align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">-Encuesta de satisfacci&#243;n</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowgroup " rowspan="3" align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">-X</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowgroup " rowspan="5" align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">-Dermatoscopia</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowgroup " rowspan="2" align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">-S&#237;ntomas gripales</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowgroup " rowspan="3" align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">-6&#8239;meses</td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">-Dolor &#243;seo y hematoma&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">-Dermatitis del scalp en FSC&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead rowgroup " rowspan="7" align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Gentile P&#44; et al&#46;<a class="elsevierStyleCrossRef" href="#bb0165"><span class="elsevierStyleSup">33</span></a></td><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowgroup " rowspan="5" align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">-A-PRP&#8239;&#43;&#8239;LLLT vs&#46; - HF-MSC&#8239;&#43;&#8239;LLLT vs&#46; placebo</td><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowgroup " rowspan="2" align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">-n&#8239;&#61;&#8239;78 &#40;57 A-PRP&#44; 21 HF-MSC&#41;&#44; 56 H&#44; 22 M</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">-Fotograf&#237;as&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowgroup " rowspan="3" align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">A las 12&#8239;semanas tras el &#250;ltimo tratamiento&#58;</td><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowgroup " rowspan="7" align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">-X</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowgroup " rowspan="6" align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">-Evaluaci&#243;n m&#233;dica y de los pacientes</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowgroup " rowspan="4" align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">-HN&#58; II-V&#44; L&#58; I-II</td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">-Incremento del recuento y de la densidad&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowgroup " rowspan="3" align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">-Incremento en la densidad capilar</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowgroup " rowspan="2" align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"></td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">-221&#8239;d&#237;as&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr></tbody></table>
                  """
              ]
              "imagenFichero" => array:1 [
                0 => "xTab2618532.png"
              ]
            ]
          ]
        ]
        "descripcion" => array:1 [
          "es" => "<p id="sp0035" class="elsevierStyleSimplePara elsevierViewall">Art&#237;culos seleccionados de tratamiento con c&#233;lulas madre de la alopecia androg&#233;nica</p>"
        ]
      ]
      4 => array:8 [
        "identificador" => "t0025"
        "etiqueta" => "Tabla 5"
        "tipo" => "MULTIMEDIATABLA"
        "mostrarFloat" => true
        "mostrarDisplay" => false
        "detalles" => array:1 [
          0 => array:3 [
            "identificador" => "al0025"
            "detalle" => "Tabla "
            "rol" => "short"
          ]
        ]
        "tabla" => array:2 [
          "leyenda" => "<p id="sp0050" class="elsevierStyleSimplePara elsevierViewall">Ca&#58; casos&#59; Co&#58; controles&#59; H&#58; hombres&#59; HN&#58; Hamilton-Norwood&#59; L&#58; Ludwig&#59; LF&#58; l&#225;ser fraccionado&#59; LLLT&#58; l&#225;ser de baja potencia&#59; M&#58; mujeres&#59; N&#58; n&#250;mero de pacientes&#59; RF&#58; radiofrecuencia fraccionada&#59; X&#58; no recogido&#46;</p>"
          "tablatextoimagen" => array:1 [
            0 => array:2 [
              "tabla" => array:1 [
                0 => """
                  <table border="0" frame="\n
                  \t\t\t\t\tvoid\n
                  \t\t\t\t" class=""><thead title="thead"><tr title="table-row"><th class="td" title="\n
                  \t\t\t\t\ttable-head\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t" scope="col" style="border-bottom: 2px solid black">Autor&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t\t\t</th><th class="td" title="\n
                  \t\t\t\t\ttable-head\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t" scope="col" style="border-bottom: 2px solid black">Aparatolog&#237;a&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t\t\t</th><th class="td" title="\n
                  \t\t\t\t\ttable-head\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t" scope="col" style="border-bottom: 2px solid black">Pacientes&#47; escalas&#47; Seguimiento&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t\t\t</th><th class="td" title="\n
                  \t\t\t\t\ttable-head\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t" scope="col" style="border-bottom: 2px solid black">Evaluaci&#243;n&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t\t\t</th><th class="td" title="\n
                  \t\t\t\t\ttable-head\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t" scope="col" style="border-bottom: 2px solid black">P&#8239;&#60;&#8239;0&#46;05&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t\t\t</th><th class="td" title="\n
                  \t\t\t\t\ttable-head\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t" scope="col" style="border-bottom: 2px solid black">Efectos adversos&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t\t\t</th></tr></thead><tbody title="tbody"><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead rowgroup " rowspan="6" align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Suchonwanit P&#44; et al&#46;<a class="elsevierStyleCrossRef" href="#bb0170"><span class="elsevierStyleSup">34</span></a></td><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowgroup " rowspan="6" align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">-RAMACAP &#40;LLLT&#41;</td><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowgroup " rowspan="2" align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">-n&#8239;&#61;&#8239;36 &#40;19 Ca &#91;10 H&#44; 9 M&#93;&#44; 17Co &#91;9 H&#44; 8 M&#93;&#41;</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">-Fotograf&#237;a con tricoscopio &#40;Follioscope&#174;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowgroup " rowspan="4" align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">A las 24&#8239;semanas&#58;</td><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowgroup " rowspan="5" align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">-Aumento de la ca&#237;da capilar &#40;n&#8239;&#61;&#8239;1&#41;</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowgroup " rowspan="5" align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">-Fotograf&#237;as valoradas por dermat&#243;logos</td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">-HN&#58; IIIv&#44; IV&#44; V&#44; L&#58; I-III&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowgroup " rowspan="3" align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">-24&#8239;semanas</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowgroup " rowspan="2" align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">-Incremento en la densidad y en el di&#225;metro&#44; mejor encuesta de satisfacci&#243;n y valoraci&#243;n fotogr&#225;fica de los investigadores</td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">-Picor leve &#40;n&#8239;&#61;&#8239;3&#41;&#40;2 Ca&#44; 1 Co&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead rowgroup " rowspan="8" align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Doghaim NN&#44; et al&#46;<a class="elsevierStyleCrossRef" href="#bb0175"><span class="elsevierStyleSup">35</span></a></td><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowgroup " rowspan="8" align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">-Carboxiterapia vs&#46; placebo</td><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowgroup " rowspan="6" align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">-n&#8239;&#61;&#8239;40 H &#40;20 Ca&#44; 20 Co&#41;</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">-Fotograf&#237;as&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowgroup " rowspan="5" align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">A las 22&#8239;semanas&#58;</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">-Dolor leve&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">-Dermatoscopia&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">-Sensaci&#243;n de quemaz&#243;n&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowgroup " rowspan="6" align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">-Autoevaluaci&#243;n</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">-Eritema&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">-Edema&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowgroup " rowspan="4" align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">-Cefalea &#40;n&#8239;&#61;&#8239;8&#41;</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowgroup " rowspan="3" align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Mejor&#237;a cl&#237;nica de los casos&#44; pero regresi&#243;n tras el cese del tratamiento</td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">-HN&#58; I-V&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">-22&#8239;semanas&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead rowgroup " rowspan="11" align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Meephansan J&#44; et al&#46;<a class="elsevierStyleCrossRef" href="#bb0180"><span class="elsevierStyleSup">36</span></a></td><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowgroup " rowspan="11" align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">-Er&#58;Glass &#40;LF&#41;</td><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowgroup " rowspan="4" align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">-n&#8239;&#61;&#8239;23 &#40;16 H&#44; 7 M&#41;</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">-Fotograf&#237;as&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowgroup " rowspan="2" align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">A los 6&#8239;meses&#58;</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">-n&#8239;&#61;&#8239;23&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowgroup " rowspan="2" align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">-Punch</td><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowgroup " rowspan="4" align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">-Dolor y picor tolerable durante la primera sesi&#243;n</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowgroup " rowspan="4" align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">-Incremento en la densidad y el di&#225;metro</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowgroup " rowspan="2" align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">-Biopsia scalp</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowgroup " rowspan="3" align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">-HN&#58; III&#44; IIIv&#44; IV&#44; L&#58; II</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowgroup " rowspan="3" align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">-Valoraci&#243;n por un dermat&#243;logo</td><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowgroup " rowspan="6" align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">-Eritema en algunos pacientes</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowgroup " rowspan="3" align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">-Incremento de los pelos terminales &#40;a los 5&#8239;meses&#41; y no de los vellosos</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowgroup " rowspan="4" align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">-6&#8239;meses</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowgroup " rowspan="3" align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">-Encuestas de satisfacci&#243;n</td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">-Reducci&#243;n del ratio velloso &#47; no vello&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">-Aumento del di&#225;metro&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead rowgroup " rowspan="7" align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Faghihi G&#44; et al&#46;<a class="elsevierStyleCrossRef" href="#bb0185"><span class="elsevierStyleSup">37</span></a></td><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowgroup " rowspan="7" align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">-LLLT&#8239;&#43;&#8239;MT5&#37; vs&#46; MT5&#37;</td><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowgroup " rowspan="3" align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">-n&#8239;&#61;&#8239;45 &#40;23 Ca&#44; 22 Co&#41;</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">-Tricograma&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowgroup " rowspan="5" align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">A los 12&#8239;meses</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">-Cefalea&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowgroup " rowspan="6" align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">-Encuesta satisfaccion</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">-Picor&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowgroup " rowspan="2" align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">-Quemaz&#243;n</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowgroup " rowspan="2" align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">-HN&#58; III-VI&#44; L&#58; II-III</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowgroup " rowspan="3" align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">-Eritema &#40;m&#225;s prevalente en controles&#41;</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowgroup " rowspan="2" align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">-12&#8239;meses</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">-Ca vs&#46; Co&#58;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Mayor recuperaci&#243;n del grado de alopecia&#44; grado de satisfacci&#243;n&#44; recuento y di&#225;metro capilar&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead rowgroup " rowspan="5" align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Verner I&#44; et al&#46;<a class="elsevierStyleCrossRef" href="#bb0190"><span class="elsevierStyleSup">38</span></a></td><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowgroup " rowspan="5" align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">-Hairlux &#174; &#40;RF&#41;</td><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowgroup " rowspan="2" align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">-n&#8239;&#61;&#8239;25 &#40;7 H&#44; 18 M&#41;</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">-Fotograf&#237;as&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowgroup " rowspan="5" align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">-X</td><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowgroup " rowspan="5" align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">-Leve hormigueo y sensibilidad hasta 24&#8239;h postratamiento</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowgroup " rowspan="3" align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">-Dermatoscopia &#40;10 pacientes&#41;</td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">-X&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowgroup " rowspan="2" align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">-7&#8239;meses</td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">-Encuestas de satisfacci&#243;n&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead rowgroup " rowspan="11" align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Suchonwanit P&#44; et al&#46;<a class="elsevierStyleCrossRef" href="#bb0195"><span class="elsevierStyleSup">39</span></a></td><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowgroup " rowspan="11" align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">-Er&#58;Glass &#40;LF&#41;&#8239;&#43;&#8239;MT5&#37; vs&#46; MT 5&#37;</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">-n&#8239;&#61;&#8239;29 H&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowgroup " rowspan="5" align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">-Fotograf&#237;a con tricoscopio &#40;Follioscope&#174;&#41;</td><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowgroup " rowspan="3" align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Ca vs&#46; Co a las 24&#8239;semanas&#58;</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Ca&#58;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">-HN&#58; III-VI&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowgroup " rowspan="3" align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">-Dolor&#8239;&#43;&#8239;quemaz&#243;n &#40;n&#8239;&#61;&#8239;9&#41;</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowgroup " rowspan="9" align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">-24 semanas</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowgroup " rowspan="8" align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">-Mejor&#237;a de la densidad&#44; el di&#225;metro&#44; la valoraci&#243;n por dermat&#243;logos y la satisfacci&#243;n de los participantes</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowgroup " rowspan="2" align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">-Eritema &#40;n&#8239;&#61;&#8239;6&#41;</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowgroup " rowspan="2" align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">-Fotograf&#237;as</td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">-Picor &#40;n&#8239;&#61;&#8239;4&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowgroup " rowspan="4" align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">-Valoraci&#243;n por dermat&#243;logos</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">-Descamaci&#243;n &#40;n&#8239;&#61;&#8239;2&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Co&#58;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">-Picor &#40;n&#8239;&#61;&#8239;5&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">-Descamaci&#243;n &#40;n&#8239;&#61;&#8239;3&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead rowgroup " rowspan="9" align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Starace M&#44; et al&#46;<a class="elsevierStyleCrossRef" href="#bb0200"><span class="elsevierStyleSup">40</span></a></td><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowgroup " rowspan="9" align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">-Microneedling</td><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowgroup " rowspan="4" align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">-n&#8239;&#61;&#8239;43 &#40;14 H&#44; 29 M&#41;</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">-Fotograf&#237;as&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowgroup " rowspan="9" align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">-X</td><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowgroup " rowspan="2" align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">-Dolor bien tolerado</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowgroup " rowspan="2" align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">-Tricoscopia</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowgroup " rowspan="3" align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">-Escaso sangrado</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowgroup " rowspan="3" align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">&#40;TrichoScan&#174;&#41;</td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">-X&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowgroup " rowspan="4" align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">-6&#8239;meses</td><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowgroup " rowspan="2" align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">-Eritema</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowgroup " rowspan="2" align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">-Pull test</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowgroup " rowspan="2" align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">-Aumento del tama&#241;o de adenopat&#237;as &#40;n&#8239;&#61;&#8239;8&#41;</td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">-Autoevaluaci&#243;n&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr></tbody></table>
                  """
              ]
              "imagenFichero" => array:1 [
                0 => "xTab2618530.png"
              ]
            ]
          ]
        ]
        "descripcion" => array:1 [
          "es" => "<p id="sp0045" class="elsevierStyleSimplePara elsevierViewall">Art&#237;culos seleccionados de tratamiento con aparataje de la alopecia androg&#233;nica</p>"
        ]
      ]
      5 => array:8 [
        "identificador" => "t0030"
        "etiqueta" => "Tabla 6"
        "tipo" => "MULTIMEDIATABLA"
        "mostrarFloat" => true
        "mostrarDisplay" => false
        "detalles" => array:1 [
          0 => array:3 [
            "identificador" => "al0030"
            "detalle" => "Tabla "
            "rol" => "short"
          ]
        ]
        "tabla" => array:2 [
          "leyenda" => "<p id="sp0060" class="elsevierStyleSimplePara elsevierViewall">FUE&#58; Follicular Unit Extraction&#59; H&#58; hombres&#59; UF&#58; unidades foliculares&#46;</p>"
          "tablatextoimagen" => array:1 [
            0 => array:2 [
              "tabla" => array:1 [
                0 => """
                  <table border="0" frame="\n
                  \t\t\t\t\tvoid\n
                  \t\t\t\t" class=""><thead title="thead"><tr title="table-row"><th class="td" title="\n
                  \t\t\t\t\ttable-head\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t" scope="col" style="border-bottom: 2px solid black">Autor&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t\t\t</th><th class="td" title="\n
                  \t\t\t\t\ttable-head\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t" scope="col" style="border-bottom: 2px solid black">Intervenci&#243;n&#47; Estudio&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t\t\t</th><th class="td" title="\n
                  \t\t\t\t\ttable-head\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t" scope="col" style="border-bottom: 2px solid black">Pacientes&#47; escalas&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t\t\t</th><th class="td" title="\n
                  \t\t\t\t\ttable-head\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t" scope="col" style="border-bottom: 2px solid black">Evaluaci&#243;n&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t\t\t</th><th class="td" title="\n
                  \t\t\t\t\ttable-head\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t" scope="col" style="border-bottom: 2px solid black">Resultados&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t\t\t</th></tr></thead><tbody title="tbody"><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead rowgroup " rowspan="5" align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Li KT&#44; et al&#46;<a class="elsevierStyleCrossRef" href="#bb0205"><span class="elsevierStyleSup">41</span></a></td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">-FUE&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowgroup " rowspan="5" align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">-n&#8239;&#61;&#8239;273 H</td><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowgroup " rowspan="5" align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">-Encuesta de satisfacci&#243;n</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">-3000-6000&#8239;UF&#47;6-12&#8239;h&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowgroup " rowspan="4" align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">-Megasesiones de implantaci&#243;n de 3000-6000&#8239;UF</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">-Tasas de supervivencia del 93&#44;5-96&#44;6&#37;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">-Satisfacci&#243;n del 81&#37;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">-Necesidad de un segundo procedimiento en un 19&#37; de los pacientes&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">-No infecciones&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr></tbody></table>
                  """
              ]
              "imagenFichero" => array:1 [
                0 => "xTab2618529.png"
              ]
            ]
          ]
        ]
        "descripcion" => array:1 [
          "es" => "<p id="sp0055" class="elsevierStyleSimplePara elsevierViewall">Art&#237;culos seleccionados de tratamiento de la alopecia androg&#233;nica con trasplante capilar</p>"
        ]
      ]
    ]
    "bibliografia" => array:2 [
      "titulo" => "Bibliograf&#237;a"
      "seccion" => array:1 [
        0 => array:2 [
          "identificador" => "bs0005"
          "bibliografiaReferencia" => array:74 [
            0 => array:3 [
              "identificador" => "bb0005"
              "etiqueta" => "1"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Estudio transversal acerca de los h&#225;bitos de prescripci&#243;n en alopecia androg&#233;nica de los dermat&#243;logos en Espa&#241;a en 2017"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:3 [
                            0 => "C&#46; Ortega-Pindado"
                            1 => "D&#46; Saceda-Corralo"
                            2 => "D&#46; Buend&#237;a-Casta&#241;o"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "Actas Dermosifiliogr&#46;"
                        "fecha" => "2018"
                        "volumen" => "109"
                        "paginaInicial" => "536"
                        "paginaFinal" => "542"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            1 => array:3 [
              "identificador" => "bb0010"
              "etiqueta" => "2"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Androgenetic alopecia&#58; a review"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:3 [
                            0 => "F&#46; Lolli"
                            1 => "F&#46; Pallotti"
                            2 => "A&#46; Rossi"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1007/s12020-017-1280-y"
                      "Revista" => array:6 [
                        "tituloSerie" => "Endocrine"
                        "fecha" => "2017"
                        "volumen" => "57"
                        "paginaInicial" => "9"
                        "paginaFinal" => "17"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/28349362"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            2 => array:3 [
              "identificador" => "bb0015"
              "etiqueta" => "3"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Confirmation of the association between male pattern baldness and the androgen receptor gene"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:4 [
                            0 => "E&#46; Levy-Nissenbaum"
                            1 => "M&#46; Bar-Natan"
                            2 => "M&#46; Frydman"
                            3 => "E&#46; Pras"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Eur J Dermatol&#46;"
                        "fecha" => "2005"
                        "volumen" => "15"
                        "paginaInicial" => "339"
                        "paginaFinal" => "340"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/16172040"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            3 => array:3 [
              "identificador" => "bb0020"
              "etiqueta" => "4"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Methods of treatment patients with androgenetic alopecia based on reference of department of dermatology in cracow"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:4 [
                            0 => "K&#46; Kozicka"
                            1 => "A&#46; &#321;ukasik"
                            2 => "M&#46; Pastuszczak"
                            3 => "A&#46; Wojas-Pelc"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "Pol Merkuriusz Lek&#46;"
                        "fecha" => "2019"
                        "volumen" => "46"
                        "paginaInicial" => "80"
                        "paginaFinal" => "83"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            4 => array:3 [
              "identificador" => "bb0025"
              "etiqueta" => "5"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Histopatolog&#237;a de las alopecias&#46; Parte I&#58; alopecias no cicatriciales"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:3 [
                            0 => "C&#46; Bern&#225;rdez"
                            1 => "A&#46;M&#46; Molina-Ruiz"
                            2 => "L&#46; Requena"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1016/j.ad.2014.07.006"
                      "Revista" => array:6 [
                        "tituloSerie" => "Actas Dermosifiliogr&#46;"
                        "fecha" => "2015"
                        "volumen" => "106"
                        "paginaInicial" => "158"
                        "paginaFinal" => "167"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/25444580"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            5 => array:3 [
              "identificador" => "bb0030"
              "etiqueta" => "6"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Teloptosis&#44; a turning point in hair shedding biorhythms"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:2 [
                            0 => "C&#46; Pi&#233;rard-Franchimont"
                            1 => "G&#46;E&#46; Pi&#233;rard"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1159/000051723"
                      "Revista" => array:6 [
                        "tituloSerie" => "Dermatology"
                        "fecha" => "2001"
                        "volumen" => "203"
                        "paginaInicial" => "115"
                        "paginaFinal" => "117"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/11586007"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            6 => array:3 [
              "identificador" => "bb0035"
              "etiqueta" => "7"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "The psychological impact of alopecia"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:2 [
                            0 => "N&#46; Hunt"
                            1 => "S&#46; McHale"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1136/bmj.331.7522.951"
                      "Revista" => array:6 [
                        "tituloSerie" => "BMJ"
                        "fecha" => "2005"
                        "volumen" => "331"
                        "paginaInicial" => "951"
                        "paginaFinal" => "953"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/16239692"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            7 => array:3 [
              "identificador" => "bb0040"
              "etiqueta" => "8"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Quality of life assessment in male patients with androgenetic alopecia&#58; result of a prospective&#44; multicenter study"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:3 [
                            0 => "S&#46;H&#46; Han"
                            1 => "J&#46;W&#46; Byun"
                            2 => "W&#46;S&#46; Lee"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.5021/ad.2012.24.3.311"
                      "Revista" => array:7 [
                        "tituloSerie" => "Ann Dermatol&#46;"
                        "fecha" => "2012"
                        "volumen" => "24"
                        "paginaInicial" => "311"
                        "paginaFinal" => "318"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/22879715"
                            "web" => "Medline"
                          ]
                        ]
                        "itemHostRev" => array:3 [
                          "pii" => "S0213911105747816"
                          "estado" => "S300"
                          "issn" => "02139111"
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            8 => array:3 [
              "identificador" => "bb0045"
              "etiqueta" => "9"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Novedades terap&#233;uticas en tricolog&#237;a"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:2 [
                            0 => "S&#46; Va&#241;&#243;-Galv&#225;n"
                            1 => "F&#46; Camacho"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "Actas Dermosifiliogr&#46;"
                        "fecha" => "2017"
                        "volumen" => "108"
                        "paginaInicial" => "221"
                        "paginaFinal" => "228"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            9 => array:3 [
              "identificador" => "bb0050"
              "etiqueta" => "10"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "The effectiveness of treatments for androgenetic alopecia&#58; a systematic review and meta-analysis"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:2 [
                            0 => "A&#46; Adil"
                            1 => "M&#46; Godwin"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1016/j.jaad.2017.02.054"
                      "Revista" => array:6 [
                        "tituloSerie" => "J Am Acad Dermatol&#46;"
                        "fecha" => "2017"
                        "volumen" => "77"
                        "paginaInicial" => "136"
                        "paginaFinal" => "141"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/28396101"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            10 => array:3 [
              "identificador" => "bb0055"
              "etiqueta" => "11"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Do kimchi and cheonggukjang probiotics as a functional food improve androgenetic alopecia&#63; A clinical pilot study"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:5 [
                            0 => "D&#46;W&#46; Park"
                            1 => "H&#46;S&#46; Lee"
                            2 => "M&#46;S&#46; Shim"
                            3 => "K&#46;J&#46; Yum"
                            4 => "J&#46;T&#46; Seo"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.5534/wjmh.180119"
                      "Revista" => array:6 [
                        "tituloSerie" => "World J Mens Health&#46;"
                        "fecha" => "2020"
                        "volumen" => "38"
                        "paginaInicial" => "95"
                        "paginaFinal" => "102"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/31385480"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            11 => array:3 [
              "identificador" => "bb0060"
              "etiqueta" => "12"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Androgenetic alopecia treatment in asian men"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:5 [
                            0 => "Y&#46; Tanaka"
                            1 => "T&#46; Aso"
                            2 => "J&#46; Ono"
                            3 => "R&#46; Hosoi"
                            4 => "T&#46; Kaneko"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "J Clin Aesthet Dermatol&#46;"
                        "fecha" => "2018"
                        "volumen" => "11"
                        "paginaInicial" => "32"
                        "paginaFinal" => "35"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/30319729"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            12 => array:3 [
              "identificador" => "bb0065"
              "etiqueta" => "13"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Evaluation of long-term efficacy of finasteride in Korean men with androgenetic alopecia using the basic and specific classification system"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:6 [
                            0 => "J&#46;W&#46; Shin"
                            1 => "E&#46;H&#46; Chung"
                            2 => "M&#46;B&#46; Kim"
                            3 => "T&#46;O&#46; Kim"
                            4 => "W&#46;I&#46; Kim"
                            5 => "C&#46;H&#46; Huh"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "J Dermatol&#46;"
                        "fecha" => "2019"
                        "volumen" => "46"
                        "paginaInicial" => "139"
                        "paginaFinal" => "143"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            13 => array:3 [
              "identificador" => "bb0070"
              "etiqueta" => "14"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Clinical efficacy of oral administration of finasteride at a dose of 2&#46;5&#8239;mg&#47;day in women with female pattern hair loss"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:3 [
                            0 => "Y&#46;Y&#46; Won"
                            1 => "B&#46;L&#46; Lew"
                            2 => "W&#46;Y&#46; Sim"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:4 [
                        "tituloSerie" => "Dermatol Ther&#46;"
                        "fecha" => "2018"
                        "volumen" => "31"
                        "itemHostRev" => array:3 [
                          "pii" => "S0300289615304877"
                          "estado" => "S300"
                          "issn" => "03002896"
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            14 => array:3 [
              "identificador" => "bb0075"
              "etiqueta" => "15"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Efficacy and safety of once-daily minoxidil foam 5&#37; versus twice-daily minoxidil solution 2&#37; in female pattern hair loss&#58; a phase III&#44; randomized&#44; investigator-blinded study"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:3 [
                            0 => "U&#46; Blume-Peytavi"
                            1 => "J&#46; Shapiro"
                            2 => "A&#46;G&#46; Messenger"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "J Drugs Dermatol&#46;"
                        "fecha" => "2016"
                        "volumen" => "15"
                        "paginaInicial" => "883"
                        "paginaFinal" => "889"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/27391640"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            15 => array:3 [
              "identificador" => "bb0080"
              "etiqueta" => "16"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "A liposome-based formulation containing equol&#44; dihomo-&#947;-linolenic acid and propionyl-l-carnitine to prevent and treat hair loss&#58; a prospective investigation"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:3 [
                            0 => "G&#46; Brotzu"
                            1 => "A&#46;M&#46; Fadda"
                            2 => "M&#46;L&#46; Manca"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:3 [
                        "tituloSerie" => "Dermatol Ther&#46;"
                        "fecha" => "2019"
                        "volumen" => "32"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            16 => array:3 [
              "identificador" => "bb0085"
              "etiqueta" => "17"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Efficacy of a cosmetic phyto-caffeine shampoo in female androgenetic alopecia"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:3 [
                            0 => "C&#46; Bussoletti"
                            1 => "M&#46;V&#46; Tolaini"
                            2 => "L&#46; Celleno"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:2 [
                        "tituloSerie" => "G Ital Dermatol Venereol&#46;"
                        "fecha" => "2018"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            17 => array:3 [
              "identificador" => "bb0090"
              "etiqueta" => "18"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Efficacy and safety of a new 10&#37; topical minoxidil versus 5&#37; topical minoxidil and placebo in the treatment of male androgenetic alopecia&#58; a trichoscopic evaluation"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:3 [
                            0 => "S&#46; Ghonemy"
                            1 => "H&#46; Bessar"
                            2 => "A&#46; Alarawi"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "J Dermatol Treat&#46;"
                        "fecha" => "2019"
                        "volumen" => "12"
                        "paginaInicial" => "1"
                        "paginaFinal" => "24"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            18 => array:3 [
              "identificador" => "bb0095"
              "etiqueta" => "19"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Efficacy and safety of a topical botanical in female androgenetic alopecia&#58; a randomized&#44; single-blinded&#44; vehicle-controlled study"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:3 [
                            0 => "A&#46;C&#46; Katoulis"
                            1 => "A&#46;I&#46; Liakou"
                            2 => "A&#46; Alevizou"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1159/000480024"
                      "Revista" => array:7 [
                        "tituloSerie" => "Skin Appendage Disord&#46;"
                        "fecha" => "2018"
                        "volumen" => "4"
                        "paginaInicial" => "160"
                        "paginaFinal" => "165"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/30197894"
                            "web" => "Medline"
                          ]
                        ]
                        "itemHostRev" => array:3 [
                          "pii" => "S0025775312007154"
                          "estado" => "S300"
                          "issn" => "00257753"
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            19 => array:3 [
              "identificador" => "bb0100"
              "etiqueta" => "20"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "A preliminary study on topical cetirizine in the therapeutic management of androgenetic alopecia"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:3 [
                            0 => "A&#46; Rossi"
                            1 => "D&#46; Campo"
                            2 => "M&#46;C&#46; Fortuna"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "J Dermatol Treat&#46;"
                        "fecha" => "2018"
                        "volumen" => "29"
                        "paginaInicial" => "149"
                        "paginaFinal" => "151"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            20 => array:3 [
              "identificador" => "bb0105"
              "etiqueta" => "21"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Treatment of male pattern alopecia with platelet-rich plasma&#58; a double-blind controlled study with analysis of platelet number and growth factor levels"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:3 [
                            0 => "B&#46;L&#46; Rodrigues"
                            1 => "S&#46;A&#46;L&#46; Montalv&#227;o"
                            2 => "R&#46;B&#46;B&#46; Cancela"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "J Am Acad Dermatol&#46;"
                        "fecha" => "2019"
                        "volumen" => "80"
                        "paginaInicial" => "694"
                        "paginaFinal" => "700"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            21 => array:3 [
              "identificador" => "bb0110"
              "etiqueta" => "22"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Efficacy of platelet-rich plasma in androgenetic alopecia patients"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:4 [
                            0 => "G&#46; Butt"
                            1 => "I&#46; Hussain"
                            2 => "F&#46;J&#46; Ahmed"
                            3 => "M&#46;S&#46; Choudhery"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1111/jocd.12810"
                      "Revista" => array:6 [
                        "tituloSerie" => "J Cosmet Dermatol&#46;"
                        "fecha" => "2019"
                        "volumen" => "18"
                        "paginaInicial" => "996"
                        "paginaFinal" => "1000"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/30393988"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            22 => array:3 [
              "identificador" => "bb0115"
              "etiqueta" => "23"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Injectable platelet-&#44; leukocyte-&#44; and fibrin-rich plasma &#40;iL-PRF&#41; in the management of androgenetic alopecia"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:4 [
                            0 => "G&#46; Schiavone"
                            1 => "A&#46; Paradisi"
                            2 => "F&#46; Ricci"
                            3 => "D&#46; Abeni"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1097/DSS.0000000000001584"
                      "Revista" => array:6 [
                        "tituloSerie" => "Dermatol Surg&#46;"
                        "fecha" => "2018"
                        "volumen" => "44"
                        "paginaInicial" => "1183"
                        "paginaFinal" => "1190"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/30045107"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            23 => array:3 [
              "identificador" => "bb0120"
              "etiqueta" => "24"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Evaluating the efficacy of different platelet-rich plasma regimens for management of androgenetic alopecia&#58; a single-center&#44; blinded&#44; randomized clinical trial"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:2 [
                            0 => "A&#46;K&#46; Hausauer"
                            1 => "D&#46;H&#46; Jones"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1097/DSS.0000000000001567"
                      "Revista" => array:6 [
                        "tituloSerie" => "Dermatol Surg&#46;"
                        "fecha" => "2018"
                        "volumen" => "44"
                        "paginaInicial" => "1191"
                        "paginaFinal" => "1200"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/30141776"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            24 => array:3 [
              "identificador" => "bb0125"
              "etiqueta" => "25"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Mechanical and controlled PRP injections in patients affected by androgenetic alopecia"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:6 [
                            0 => "P&#46; Gentile"
                            1 => "S&#46; Garcovich"
                            2 => "M&#46;G&#46; Scioli"
                            3 => "A&#46; Bielli"
                            4 => "A&#46; Orlandi"
                            5 => "V&#46; Cervelli"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "J Vis Exp&#46;"
                        "fecha" => "2018"
                        "volumen" => "7"
                        "paginaInicial" => "131"
                        "itemHostRev" => array:3 [
                          "pii" => "S1699258X14000813"
                          "estado" => "S300"
                          "issn" => "1699258X"
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            25 => array:3 [
              "identificador" => "bb0130"
              "etiqueta" => "26"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Platelet-rich plasma injections in the treatment of male androgenetic alopecia&#58; a randomized placebo-controlled crossover study"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:3 [
                            0 => "&#214;&#46; Dicle"
                            1 => "A&#46; Bilgic Temel"
                            2 => "K&#46;H&#46; G&#252;lkesen"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "J Cosmet Dermatol&#46;"
                        "fecha" => "2019"
                        "volumen" => "19"
                        "paginaInicial" => "1071"
                        "paginaFinal" => "1077"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            26 => array:3 [
              "identificador" => "bb0135"
              "etiqueta" => "27"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "A study to compare the efficacy of platelet-rich plasma and minoxidil therapy for the treatment of androgenetic alopecia"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:6 [
                            0 => "K&#46; Verma"
                            1 => "G&#46;R&#46; Tegta"
                            2 => "G&#46; Verma"
                            3 => "M&#46; Gupta"
                            4 => "A&#46; Negi"
                            5 => "R&#46; Sharma"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "Int J Trichol&#46;"
                        "fecha" => "2019"
                        "volumen" => "11"
                        "paginaInicial" => "68"
                        "paginaFinal" => "79"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            27 => array:3 [
              "identificador" => "bb0140"
              "etiqueta" => "28"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Efficacy of platelet-rich plasma for treating androgenic alopecia of varying grades"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:3 [
                            0 => "Q&#46; Qu"
                            1 => "P&#46; Shi"
                            2 => "Y&#46; Yi"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "Clin Drug Invest&#46;"
                        "fecha" => "2019"
                        "volumen" => "39"
                        "paginaInicial" => "865"
                        "paginaFinal" => "872"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            28 => array:3 [
              "identificador" => "bb0145"
              "etiqueta" => "29"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Platelet-rich plasma on female androgenetic alopecia&#58; tested on 10 patients"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:3 [
                            0 => "M&#46; Starace"
                            1 => "A&#46; Alessandrini"
                            2 => "C&#46; D&#39;Acunto"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1111/jocd.12550"
                      "Revista" => array:6 [
                        "tituloSerie" => "J Cosmet Dermatol&#46;"
                        "fecha" => "2019"
                        "volumen" => "18"
                        "paginaInicial" => "59"
                        "paginaFinal" => "64"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/29707872"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            29 => array:3 [
              "identificador" => "bb0150"
              "etiqueta" => "30"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "The effect of platelet-rich plasma injection in the treatment of androgenetic alopecia"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:5 [
                            0 => "M&#46; Bayat"
                            1 => "M&#46;J&#46; Yazdanpanah"
                            2 => "D&#46; Hamidi Alamdari"
                            3 => "M&#46; Banihashemi"
                            4 => "M&#46; Salehi"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "J Cosmet Dermatol&#46;"
                        "fecha" => "2019"
                        "volumen" => "18"
                        "paginaInicial" => "1624"
                        "paginaFinal" => "1628"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            30 => array:3 [
              "identificador" => "bb0155"
              "etiqueta" => "31"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Platelet-rich plasma and microneedling improves hair growth in patients of androgenetic alopecia when used as an adjuvant to minoxidil"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:6 [
                            0 => "A&#46;K&#46; Jha"
                            1 => "K&#46; Vinay"
                            2 => "M&#46; Zeeshan"
                            3 => "P&#46;K&#46; Roy"
                            4 => "R&#46;K&#46;P&#46; Chaudhary"
                            5 => "A&#46; Priya"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:2 [
                        "tituloSerie" => "J Cosmet Dermatol&#46;"
                        "fecha" => "2019"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            31 => array:3 [
              "identificador" => "bb0160"
              "etiqueta" => "32"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Stem cell therapy as a novel therapeutic intervention for resistant cases of alopecia areata and androgenetic alopecia"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:3 [
                            0 => "I&#46;H&#46; Elmaadawi"
                            1 => "B&#46;M&#46; Mohamed"
                            2 => "Z&#46;A&#46;S&#46; Ibrahim"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "J Dermatol Treat&#46;"
                        "fecha" => "2018"
                        "volumen" => "29"
                        "paginaInicial" => "431"
                        "paginaFinal" => "440"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            32 => array:3 [
              "identificador" => "bb0165"
              "etiqueta" => "33"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Platelet-rich plasma and micrografts enriched with autologous human follicle mesenchymal stem cells improve hair re-growth in androgenetic alopecia"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:3 [
                            0 => "P&#46; Gentile"
                            1 => "M&#46;G&#46; Scioli"
                            2 => "A&#46; Bielli"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:4 [
                        "tituloSerie" => "Biomedicines"
                        "fecha" => "2019"
                        "volumen" => "8"
                        "paginaInicial" => "7"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            33 => array:3 [
              "identificador" => "bb0170"
              "etiqueta" => "34"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Low-level laser therapy for the treatment of androgenetic alopecia in Thai men and women&#58; a 24-week&#44; randomized&#44; double-blind&#44; sham device-controlled trial"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:3 [
                            0 => "P&#46; Suchonwanit"
                            1 => "N&#46; Chalermroj"
                            2 => "S&#46; Khunkhet"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1007/s10103-018-02699-9"
                      "Revista" => array:6 [
                        "tituloSerie" => "Lasers Med Sci&#46;"
                        "fecha" => "2019"
                        "volumen" => "34"
                        "paginaInicial" => "1107"
                        "paginaFinal" => "1114"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/30569416"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            34 => array:3 [
              "identificador" => "bb0175"
              "etiqueta" => "35"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Study of the efficacy of carboxytherapy in alopecia"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:4 [
                            0 => "N&#46;N&#46; Doghaim"
                            1 => "R&#46;A&#46; El-Tatawy"
                            2 => "Y&#46;M&#46;E&#46; Neinaa"
                            3 => "M&#46;M&#46; Abd El-Samd"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1111/jocd.12501"
                      "Revista" => array:6 [
                        "tituloSerie" => "J Cosmet Dermatol&#46;"
                        "fecha" => "2018"
                        "volumen" => "17"
                        "paginaInicial" => "1275"
                        "paginaFinal" => "1285"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/29460509"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            35 => array:3 [
              "identificador" => "bb0180"
              "etiqueta" => "36"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Efficacy of 1550-nm erbium-glass fractional laser treatment and its effect on the expression of insulin-like growth factor 1 and Wnt&#47;&#946;-catenin in androgenetic alopecia"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:5 [
                            0 => "J&#46; Meephansan"
                            1 => "N&#46; Ungpraphakorn"
                            2 => "S&#46; Ponnikorn"
                            3 => "P&#46; Suchonwanit"
                            4 => "Y&#46; Poovorawan"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1097/DSS.0000000000001619"
                      "Revista" => array:6 [
                        "tituloSerie" => "Dermatol Surg&#46;"
                        "fecha" => "2018"
                        "volumen" => "44"
                        "paginaInicial" => "1295"
                        "paginaFinal" => "1303"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/30096107"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            36 => array:3 [
              "identificador" => "bb0185"
              "etiqueta" => "37"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "The effectiveness of adding low-level light therapy to minoxidil 5&#37; solution in the treatment of patients with androgenetic alopecia"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:3 [
                            0 => "G&#46; Faghihi"
                            1 => "S&#46; Mozafarpoor"
                            2 => "A&#46; Asilian"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "Indian J Dermatol Venereol Leprol&#46;"
                        "fecha" => "2018"
                        "volumen" => "84"
                        "paginaInicial" => "547"
                        "paginaFinal" => "553"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            37 => array:3 [
              "identificador" => "bb0190"
              "etiqueta" => "38"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Clinical evaluation of a novel fractional radiofrequency device for hair growth&#58; fractional radiofrequency for hair growth stimulation"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:2 [
                            0 => "I&#46; Verner"
                            1 => "T&#46; Lotti"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:3 [
                        "tituloSerie" => "Dermatol Ther&#46;"
                        "fecha" => "2018"
                        "volumen" => "31"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            38 => array:3 [
              "identificador" => "bb0195"
              "etiqueta" => "39"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "A randomized&#44; investigator-blinded&#44; controlled&#44; split-scalp study of the efficacy and safety of a 1550-nm fractional erbium-glass laser&#44; used in combination with topical 5&#37; minoxidil versus 5&#37; minoxidil alone&#44; for the treatment of androgenetic alopecia"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:3 [
                            0 => "P&#46; Suchonwanit"
                            1 => "S&#46; Rojhirunsakool"
                            2 => "S&#46; Khunkhet"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1007/s10103-019-02783-8"
                      "Revista" => array:6 [
                        "tituloSerie" => "Lasers Med Sci&#46;"
                        "fecha" => "2019"
                        "volumen" => "34"
                        "paginaInicial" => "1857"
                        "paginaFinal" => "1864"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/30982177"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            39 => array:3 [
              "identificador" => "bb0200"
              "etiqueta" => "40"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Preliminary results of the use of scalp microneedling in different types of alopecia"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:4 [
                            0 => "M&#46; Starace"
                            1 => "A&#46; Alessandrini"
                            2 => "N&#46; Brandi"
                            3 => "B&#46;M&#46; Piraccini"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1111/jocd.13061"
                      "Revista" => array:7 [
                        "tituloSerie" => "J Cosmet Dermatol&#46;"
                        "fecha" => "2019"
                        "volumen" => "19"
                        "paginaInicial" => "646"
                        "paginaFinal" => "650"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/31254437"
                            "web" => "Medline"
                          ]
                        ]
                        "itemHostRev" => array:3 [
                          "pii" => "S0213911117303151"
                          "estado" => "S300"
                          "issn" => "02139111"
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            40 => array:3 [
              "identificador" => "bb0205"
              "etiqueta" => "41"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Clinical experience on follicular unit extraction megasession for severe androgenetic alopecia"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:3 [
                            0 => "K&#46;T&#46; Li"
                            1 => "Q&#46; Qu"
                            2 => "Z&#46;X&#46; Fan"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1111/jocd.13458"
                      "Revista" => array:4 [
                        "tituloSerie" => "J Cosmet Dermatol&#46;"
                        "fecha" => "2019"
                        "volumen" => "19"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/32449835"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            41 => array:3 [
              "identificador" => "bb0210"
              "etiqueta" => "42"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Androgenetic alopecia&#58; an evidence-based treatment update"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:2 [
                            0 => "S&#46; Varothai"
                            1 => "W&#46;F&#46; Bergfeld"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1007/s40257-014-0077-5"
                      "Revista" => array:7 [
                        "tituloSerie" => "Am J Clin Dermatol&#46;"
                        "fecha" => "2014"
                        "volumen" => "15"
                        "paginaInicial" => "217"
                        "paginaFinal" => "230"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/24848508"
                            "web" => "Medline"
                          ]
                        ]
                        "itemHostRev" => array:3 [
                          "pii" => "S0213911118301638"
                          "estado" => "S300"
                          "issn" => "02139111"
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            42 => array:3 [
              "identificador" => "bb0215"
              "etiqueta" => "43"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Minoxidil in the treatment of androgenetic alopecia"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:2 [
                            0 => "A&#46; Goren"
                            1 => "T&#46; Naccarato"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:3 [
                        "tituloSerie" => "Dermatol Ther&#46;"
                        "fecha" => "2018"
                        "volumen" => "31"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            43 => array:3 [
              "identificador" => "bb0220"
              "etiqueta" => "44"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Minoxidil and its use in hair disorders&#58; a review"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:3 [
                            0 => "P&#46; Suchonwanit"
                            1 => "S&#46; Thammarucha"
                            2 => "K&#46; Leerunyakul"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.2147/DDDT.S214907"
                      "Revista" => array:6 [
                        "tituloSerie" => "Drug Des Devel Ther&#46;"
                        "fecha" => "2019"
                        "volumen" => "13"
                        "paginaInicial" => "2777"
                        "paginaFinal" => "2786"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/31496654"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            44 => array:3 [
              "identificador" => "bb0225"
              "etiqueta" => "45"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Laser-assisted drug delivery for the treatment of androgenetic alopecia&#58; ablative laser fractional photothermolysis to enhance cutaneous topical delivery of platelet-rich plasma - with or without concurrent bimatoprost and&#47;or minoxidil"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:1 [
                            0 => "P&#46;R&#46; Cohen"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:4 [
                        "tituloSerie" => "Dermatol Online J&#46;"
                        "fecha" => "2019"
                        "volumen" => "15"
                        "paginaInicial" => "25"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            45 => array:3 [
              "identificador" => "bb0230"
              "etiqueta" => "46"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Low-dose daily aspirin reduces topical minoxidil efficacy in androgenetic alopecia patients"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:3 [
                            0 => "A&#46; Goren"
                            1 => "A&#46; Sharma"
                            2 => "R&#46; Dhurat"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:3 [
                        "tituloSerie" => "Dermatol Ther&#46;"
                        "fecha" => "2018"
                        "volumen" => "31"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            46 => array:3 [
              "identificador" => "bb0235"
              "etiqueta" => "47"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Tretinoin enhances minoxidil response in androgenetic alopecia patients by upregulating follicular sulfotransferase enzymes"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:3 [
                            0 => "A&#46; Sharma"
                            1 => "A&#46; Goren"
                            2 => "R&#46; Dhurat"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:3 [
                        "tituloSerie" => "Dermatol Ther&#46;"
                        "fecha" => "2019"
                        "volumen" => "32"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            47 => array:3 [
              "identificador" => "bb0240"
              "etiqueta" => "48"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Reply to &#171;Very low dose oral minoxidil in male androgenetic alopecia&#58; a study with quantitative trichoscopic documentation&#187;"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:6 [
                            0 => "J&#46; Jimenez-Cauhe"
                            1 => "D&#46; Saceda-Corralo"
                            2 => "O&#46;M&#46; Moreno-Arrones"
                            3 => "D&#46; Ortega-Quijano"
                            4 => "D&#46; Fernandez-Nieto"
                            5 => "S&#46; Va&#241;o-Galvan"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1016/j.jaad.2019.08.085"
                      "Revista" => array:6 [
                        "tituloSerie" => "J Am Acad Dermatol&#46;"
                        "fecha" => "2020"
                        "volumen" => "82"
                        "paginaInicial" => "e23"
                        "paginaFinal" => "e24"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/31520659"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            48 => array:3 [
              "identificador" => "bb0245"
              "etiqueta" => "49"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Very low dose oral minoxidil in male androgenetic alopecia&#58; a study with quantitative trichoscopic documentation"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:2 [
                            0 => "R&#46; Pirmez"
                            1 => "C&#46;I&#46; Salas-Callo"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1016/j.jaad.2019.08.084"
                      "Revista" => array:6 [
                        "tituloSerie" => "J Am Acad Dermatol&#46;"
                        "fecha" => "2020"
                        "volumen" => "82"
                        "paginaInicial" => "e21"
                        "paginaFinal" => "e22"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/31520662"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            49 => array:3 [
              "identificador" => "bb0250"
              "etiqueta" => "50"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Female pattern hair loss&#58; a pilot study investigating combination therapy with low-dose oral minoxidil and spironolactone"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:1 [
                            0 => "R&#46;D&#46; Sinclair"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1111/ijd.13838"
                      "Revista" => array:6 [
                        "tituloSerie" => "Int J Dermatol&#46;"
                        "fecha" => "2018"
                        "volumen" => "57"
                        "paginaInicial" => "104"
                        "paginaFinal" => "109"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/29231239"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            50 => array:3 [
              "identificador" => "bb0255"
              "etiqueta" => "51"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:1 [
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:4 [
                            0 => "P&#46;M&#46; Ramos"
                            1 => "R&#46;D&#46; Sinclair"
                            2 => "M&#46; Kasprzak"
                            3 => "H&#46;A&#46; Miot"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1016/j.jaad.2019.08.060"
                      "Revista" => array:6 [
                        "tituloSerie" => "J Am Acad Dermatol&#46;"
                        "fecha" => "2020"
                        "volumen" => "82"
                        "paginaInicial" => "252"
                        "paginaFinal" => "253"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/31473295"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            51 => array:3 [
              "identificador" => "bb0260"
              "etiqueta" => "52"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Efficacy and safety of finasteride therapy for androgenetic alopecia&#58; a systematic review"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:5 [
                            0 => "J&#46;M&#46; Mella"
                            1 => "M&#46;C&#46; Perret"
                            2 => "M&#46; Manzotti"
                            3 => "H&#46;N&#46; Catalano"
                            4 => "G&#46; Guyatt"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1001/archdermatol.2010.256"
                      "Revista" => array:6 [
                        "tituloSerie" => "Arch Dermatol&#46;"
                        "fecha" => "2010"
                        "volumen" => "146"
                        "paginaInicial" => "1141"
                        "paginaFinal" => "1150"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/20956649"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            52 => array:3 [
              "identificador" => "bb0265"
              "etiqueta" => "53"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Finasteride for androgenetic alopecia is not associated with sexual dysfunction&#58; a survey-based&#44; single-centre&#44; controlled study"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:5 [
                            0 => "R&#46;S&#46; Haber"
                            1 => "A&#46;K&#46; Gupta"
                            2 => "E&#46; Epstein"
                            3 => "J&#46;L&#46; Carviel"
                            4 => "K&#46;A&#46; Foley"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1111/jdv.15548"
                      "Revista" => array:6 [
                        "tituloSerie" => "J Eur Acad Dermatol Venereol&#46;"
                        "fecha" => "2019"
                        "volumen" => "33"
                        "paginaInicial" => "1393"
                        "paginaFinal" => "1397"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/30835851"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            53 => array:3 [
              "identificador" => "bb0270"
              "etiqueta" => "54"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Adverse effects and safety of 5-alpha reductase inhibitors &#40;Finasteride&#44; Dutasteride&#41;&#58; a systematic review"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:5 [
                            0 => "J&#46;M&#46; Hirshburg"
                            1 => "P&#46;A&#46; Kelsey"
                            2 => "C&#46;A&#46; Therrien"
                            3 => "A&#46;C&#46; Gavino"
                            4 => "J&#46;S&#46; Reichenberg"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "J Clin Aesthet Dermatol&#46;"
                        "fecha" => "2016"
                        "volumen" => "9"
                        "paginaInicial" => "56"
                        "paginaFinal" => "62"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/27672412"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            54 => array:3 [
              "identificador" => "bb0275"
              "etiqueta" => "55"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "The efficacy and use of finasteride in women&#58; a systematic review"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:3 [
                            0 => "A&#46;C&#46; Hu"
                            1 => "L&#46;W&#46; Chapman"
                            2 => "N&#46;A&#46; Mesinkovska"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1111/ijd.14370"
                      "Revista" => array:7 [
                        "tituloSerie" => "Int J Dermatol&#46;"
                        "fecha" => "2019"
                        "volumen" => "58"
                        "paginaInicial" => "759"
                        "paginaFinal" => "776"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/30604525"
                            "web" => "Medline"
                          ]
                        ]
                        "itemHostRev" => array:3 [
                          "pii" => "S0213911111000872"
                          "estado" => "S300"
                          "issn" => "02139111"
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            55 => array:3 [
              "identificador" => "bb0280"
              "etiqueta" => "56"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "The efficacy and safety of dutasteride compared with finasteride in treating men with androgenetic alopecia&#58; a systematic review and meta-analysis"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:6 [
                            0 => "Z&#46; Zhou"
                            1 => "S&#46; Song"
                            2 => "Z&#46; Gao"
                            3 => "J&#46; Wu"
                            4 => "J&#46; Ma"
                            5 => "Y&#46; Cui"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.2147/CIA.S192435"
                      "Revista" => array:6 [
                        "tituloSerie" => "Clin Interv Aging&#46;"
                        "fecha" => "2019"
                        "volumen" => "14"
                        "paginaInicial" => "399"
                        "paginaFinal" => "406"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/30863034"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            56 => array:3 [
              "identificador" => "bb0285"
              "etiqueta" => "57"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "A systematic review of topical finasteride in the treatment of androgenetic alopecia in men and women"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:5 [
                            0 => "S&#46;W&#46; Lee"
                            1 => "M&#46; Juhasz"
                            2 => "P&#46; Mobasher"
                            3 => "C&#46; Ekelem"
                            4 => "N&#46;A&#46; Mesinkovska"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "J Drugs Dermatol&#46;"
                        "fecha" => "2018"
                        "volumen" => "17"
                        "paginaInicial" => "457"
                        "paginaFinal" => "463"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/29601622"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            57 => array:3 [
              "identificador" => "bb0290"
              "etiqueta" => "58"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "The efficacy of latanoprost in the treatment of alopecia areata of eyelashes and eyebrows"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:3 [
                            0 => "G&#46; Faghihi"
                            1 => "F&#46; Andalib"
                            2 => "A&#46; Asilian"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1684/ejd.2009.0766"
                      "Revista" => array:6 [
                        "tituloSerie" => "Eur J Dermatol&#46;"
                        "fecha" => "2009"
                        "volumen" => "19"
                        "paginaInicial" => "586"
                        "paginaFinal" => "587"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/19620039"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            58 => array:3 [
              "identificador" => "bb0295"
              "etiqueta" => "59"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "The use of phosphodiesterase inhibitors for the treatment of alopecia"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:2 [
                            0 => "M&#46;L&#46;W&#46; Juh&#225;sz"
                            1 => "N&#46;A&#46; Mesinkovska"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "J Dermatol Treat&#46;"
                        "fecha" => "2019"
                        "volumen" => "2"
                        "paginaInicial" => "1"
                        "paginaFinal" => "8"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            59 => array:3 [
              "identificador" => "bb0300"
              "etiqueta" => "60"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Cellium&#174; GC&#58; evaluation of a new natural active ingredient in 210&#8239;mg&#47;ml topical solution through scalp biopsy"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:3 [
                            0 => "L&#46;C&#46; Cuc&#233;"
                            1 => "C&#46;J&#46; Rodrigues"
                            2 => "R&#46;C&#46;R&#46; Patriota"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "Sug Cosmet Dermatol&#46;"
                        "fecha" => "2011"
                        "volumen" => "3"
                        "paginaInicial" => "123"
                        "paginaFinal" => "128"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            60 => array:3 [
              "identificador" => "bb0305"
              "etiqueta" => "61"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Platelet-rich plasma peptides&#58; key for regeneration"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:3 [
                            0 => "D&#46;J&#46; S&#225;nchez-Gonz&#225;lez"
                            1 => "E&#46; M&#233;ndez-Bolaina"
                            2 => "N&#46;I&#46; Trejo-Bahena"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:4 [
                        "tituloSerie" => "Int J Pept&#46;"
                        "fecha" => "2012"
                        "volumen" => "5"
                        "paginaInicial" => "519"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            61 => array:3 [
              "identificador" => "bb0310"
              "etiqueta" => "62"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "The role of platelet growth factors in male pattern baldness surgery"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:4 [
                            0 => "C&#46;O&#46; Uebel"
                            1 => "J&#46;B&#46; Da Silva"
                            2 => "D&#46; Cantarelli"
                            3 => "P&#46; Martins"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1097/01.prs.0000239560.29172.33"
                      "Revista" => array:6 [
                        "tituloSerie" => "Plast Reconstr Surg&#46;"
                        "fecha" => "2006"
                        "volumen" => "118"
                        "paginaInicial" => "1458"
                        "paginaFinal" => "1466"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/17051119"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            62 => array:3 [
              "identificador" => "bb0315"
              "etiqueta" => "63"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "The effect of plasma rich in growth factors on a pattern hair loss&#58; a pilot study"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:5 [
                            0 => "E&#46; Anitua"
                            1 => "A&#46; Pino"
                            2 => "N&#46; Martinez"
                            3 => "G&#46; Orive"
                            4 => "D&#46; Berridi"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1097/DSS.0000000000001049"
                      "Revista" => array:6 [
                        "tituloSerie" => "Dermatol Surg&#46;"
                        "fecha" => "2017"
                        "volumen" => "43"
                        "paginaInicial" => "658"
                        "paginaFinal" => "670"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/28221183"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            63 => array:3 [
              "identificador" => "bb0320"
              "etiqueta" => "64"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Efficacy of platelet-rich plasma in the treatment of androgenetic &#40;male-patterned&#41; alopecia&#58; a pilot randomized controlled trial"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:3 [
                            0 => "M&#46;A&#46; Mapar"
                            1 => "S&#46; shahriari"
                            2 => "M&#46;H&#46; Haghighizadeh"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1080/14764172.2016.1225963"
                      "Revista" => array:6 [
                        "tituloSerie" => "J Cosmet Laser Ther&#46;"
                        "fecha" => "2016"
                        "volumen" => "18"
                        "paginaInicial" => "452"
                        "paginaFinal" => "455"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/27593381"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            64 => array:3 [
              "identificador" => "bb0325"
              "etiqueta" => "65"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Platelet-rich for treating androgenic alopecia&#58; a systematic review"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:3 [
                            0 => "G&#46; Mao"
                            1 => "G&#46; Zhang"
                            2 => "W&#46; Fan"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "Aesthetic Plast Surg&#46;"
                        "fecha" => "2019"
                        "volumen" => "43"
                        "paginaInicial" => "1326"
                        "paginaFinal" => "1336"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            65 => array:3 [
              "identificador" => "bb0330"
              "etiqueta" => "66"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:1 [
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:6 [
                            0 => "A&#46; Gupta"
                            1 => "S&#46; Versteeg"
                            2 => "J&#46; Rapaport"
                            3 => "A&#46; Hausauer"
                            4 => "N&#46; Shear"
                            5 => "V&#46; Piguet"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1177/1203475418818073"
                      "Revista" => array:6 [
                        "tituloSerie" => "J Cutan Med Surg&#46;"
                        "fecha" => "2019"
                        "volumen" => "23"
                        "paginaInicial" => "185"
                        "paginaFinal" => "203"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/30606055"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            66 => array:3 [
              "identificador" => "bb0335"
              "etiqueta" => "67"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Platelet-rich plasma and its utilities in alopecia&#58; a systematic review"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:2 [
                            0 => "M&#46;J&#46; Hesseler"
                            1 => "N&#46; Shyam"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1097/DSS.0000000000001965"
                      "Revista" => array:6 [
                        "tituloSerie" => "Dermatol Surg&#46;"
                        "fecha" => "2020"
                        "volumen" => "46"
                        "paginaInicial" => "93"
                        "paginaFinal" => "102"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/31211715"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            67 => array:3 [
              "identificador" => "bb0340"
              "etiqueta" => "68"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Platelet-rich plasma for the treatment of androgenic alopecia&#58; a systematic review"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:3 [
                            0 => "J&#46; Chen"
                            1 => "N&#46; Justicz"
                            2 => "L&#46; Lee"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1055/s-0038-1660845"
                      "Revista" => array:6 [
                        "tituloSerie" => "Facial Plast Surg&#46;"
                        "fecha" => "2018"
                        "volumen" => "34"
                        "paginaInicial" => "631"
                        "paginaFinal" => "640"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/29954021"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            68 => array:3 [
              "identificador" => "bb0345"
              "etiqueta" => "69"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Systematic review of platelet-rich plasma &#40;PRP&#41; preparation and composition for the treatment of androgenic alopecia"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:2 [
                            0 => "M&#46;J&#46; Kramer"
                            1 => "T&#46; Keaney"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1111/jocd.12679"
                      "Revista" => array:6 [
                        "tituloSerie" => "J Cosmet Dermatol&#46;"
                        "fecha" => "2018"
                        "volumen" => "17"
                        "paginaInicial" => "666"
                        "paginaFinal" => "671"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/29790267"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            69 => array:3 [
              "identificador" => "bb0350"
              "etiqueta" => "70"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Platelet rich plasma in androgenetic alopecia&#58; a systematic review"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:5 [
                            0 => "T&#46; Lotti"
                            1 => "A&#46; Goren"
                            2 => "I&#46; Verner"
                            3 => "A&#46; D&#39;Alessio Patrizia"
                            4 => "K&#46; Franca"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:3 [
                        "tituloSerie" => "Dermatol Ther&#46;"
                        "fecha" => "2019"
                        "volumen" => "32"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            70 => array:3 [
              "identificador" => "bb0355"
              "etiqueta" => "71"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Shedding light on the FDA&#39;s 510&#40;k&#41; approvals process&#58; low-level laser therapy devices used in the treatment of androgenetic alopecia"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:3 [
                            0 => "S&#46; Wang"
                            1 => "D&#46; Seth"
                            2 => "H&#46; Ezaldein"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "J Dermatol Treat&#46;"
                        "fecha" => "2019"
                        "volumen" => "30"
                        "paginaInicial" => "489"
                        "paginaFinal" => "491"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            71 => array:3 [
              "identificador" => "bb0360"
              "etiqueta" => "72"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Quantitative proteomic analysis of dermal papilla from male androgenetic alopecia comparing before and after treatment with low-level laser therapy"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:3 [
                            0 => "R&#46; Panchaprateep"
                            1 => "T&#46; Pisitkun"
                            2 => "N&#46; Kalpongnukul"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1002/lsm.23074"
                      "Revista" => array:6 [
                        "tituloSerie" => "Lasers Surg Med&#46;"
                        "fecha" => "2019"
                        "volumen" => "51"
                        "paginaInicial" => "600"
                        "paginaFinal" => "608"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/30843235"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            72 => array:3 [
              "identificador" => "bb0365"
              "etiqueta" => "73"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Efficacy of fractional lasers in treating alopecia&#58; a literature review"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:5 [
                            0 => "M&#46; Perper"
                            1 => "A&#46;S&#46; Aldahan"
                            2 => "R&#46;A&#46; Fayne"
                            3 => "C&#46;P&#46; Emerson"
                            4 => "K&#46; Nouri"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "Lasers Med Sci&#46;"
                        "fecha" => "2017"
                        "volumen" => "32"
                        "paginaInicial" => "1919"
                        "paginaFinal" => "1925"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            73 => array:3 [
              "identificador" => "bb0370"
              "etiqueta" => "74"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Fractional laser-assisted hair regrowth and microneedling for the treatment of alopecia areata&#58; a review"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:5 [
                            0 => "R&#46;J&#46; Dabek"
                            1 => "D&#46;S&#46; Roh"
                            2 => "D&#46; Ozdemir"
                            3 => "W&#46;G&#46; Austen Jr&#46;"
                            4 => "B&#46; Bojovic"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:3 [
                        "tituloSerie" => "Cureus"
                        "fecha" => "2019"
                        "volumen" => "11"
                      ]
                    ]
                  ]
                ]
              ]
            ]
          ]
        ]
      ]
    ]
  ]
  "idiomaDefecto" => "es"
  "url" => "/02139251/0000003600000006/v1_202106100533/S0213925120303087/v1_202106100533/es/main.assets"
  "Apartado" => array:4 [
    "identificador" => "8169"
    "tipo" => "SECCION"
    "en" => array:2 [
      "titulo" => "Terap&#233;utica dermatol&#243;gica"
      "idiomaDefecto" => true
    ]
    "idiomaDefecto" => "en"
  ]
  "PDF" => "https://static.elsevier.es/multimedia/02139251/0000003600000006/v1_202106100533/S0213925120303087/v1_202106100533/es/main.pdf?idApp=UINPBA00004N&text.app=https://www.elsevier.es/"
  "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0213925120303087?idApp=UINPBA00004N"
]

Información del artículo

ISSN: 02139251
Idioma original: Español

DOI:10.1016/j.piel.2020.05.012

Datos actualizados diariamente

año/Mes	Html	Pdf	Total

2024 Noviembre	2	2	4
2024 Octubre	7	7	14
2024 Septiembre	12	14	26
2024 Agosto	15	12	27
2024 Julio	15	14	29
2024 Junio	10	10	20
2024 Mayo	14	13	27
2024 Abril	13	11	24
2024 Marzo	11	11	22
2024 Febrero	12	6	18
2024 Enero	20	0	20
2023 Diciembre	10	0	10
2023 Noviembre	8	0	8
2023 Octubre	35	0	35
2023 Septiembre	10	6	16
2023 Agosto	18	0	18
2023 Julio	15	2	17
2023 Junio	3	4	7
2023 Mayo	2	2	4
2023 Abril	2	0	2
2023 Marzo	4	1	5
2022 Noviembre	4	4	8
2022 Octubre	6	6	12
2022 Septiembre	5	7	12
2022 Abril	2	0	2
2021 Diciembre	0	2	2
2021 Noviembre	0	2	2
2021 Octubre	2	0	2
2021 Septiembre	4	2	6
2021 Agosto	3	2	5
2021 Julio	7	8	15
2021 Junio	5	2	7
2021 Abril	0	8	8

Mostrar todo

Indexada en:

Síguenos:

Suscribirse:

Estadísticas

Indexada en:

Síguenos:

Suscribirse:

Estadísticas

Suscríbase a la newsletter