Aim: To identify the relationship between the condition of utero-placento-foetal circulation with the clinical course of gestational process and its impact on perinatal outcome.
Introduction: The period of foetal development before birth is so extensive however, only a small part of the duration of this period, which largely determines the quality of his later life. It is a proven fact that the events during the prenatal period effects the outcomes of pregnancy which are favourable in childbirth, later leading to diseases in adulthood.
Methods: We analysed the course of pregnancy, delivery, the condition of the foetus and newborn from 72 pregnant women (24–41 weeks of gestation) with placental dysfunction at the 3rd Maternity Hospital, Zaporozhye.
Results: According to CT, distress of the foetus were confirmed in 22.7% of pregnant women with impaired hemodynamics I-A degree, 24.8% with impaired hemodynamics, at 30.6% with circulatory disorders of the II degree. On analysis of the hemodynamics in the system of maternal-placento-foetal revealed violations of IPC(I-A) in 46% of cases, ACC(I-B) at 28.7%, IPC and SPC(II) at 12.7%, critical blood vessels PPK(III) and 3.4% of cases. The frequency of caesarean section in pregnant women with dysfunction of placenta was 28.2%, of which the foetal distress was 22.4%, vacuum extraction of the foetus were used in 3.2%. The analysis of the development of newborn from mothers with placental dysfunction, identified the violation of their status at birth and Apgar score 7–5 points received at birth 11.2% of newborn.
Conclusion: Analysis of indicators of physical development of newborns in the early neonatal period were distinguished by the presence of signs of functional immaturity. Clinical and statistical analysis conducted revealed a high frequency of complications of pregnancy and childbirth in women with dysfunction of the placenta.
Acknowledgements: I would like to express my special thanks of gratitude to my associate professor Nataliya Victorovna Gaidai as well as my co-authors Varahabhatla Vamsi and Katnam Sahithi who gave me this golden opportunity to do this wonderful project on the topic. The role of the state of uterine placental foetal circulation on the clinical course of gestational processes and it's impact on perinatal outcome. Secondly, I would also like to thank my parents and friends who helped me a lot in finalizing this project within the limited time frame.