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Inicio Progresos de Obstetricia y Ginecología Actividad biológica de los compartimientos extraembrionarios
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Vol. 47. Núm. 4.
Páginas 177-185 (enero 2004)
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Vol. 47. Núm. 4.
Páginas 177-185 (enero 2004)
Acceso a texto completo
Actividad biológica de los compartimientos extraembrionarios
Biological activity of the extraembryonic compartments
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7763
J.A. de Leóna,c,
Autor para correspondencia
jleon@ama.ttuhsc.edu

Correspondencia: Texas Tech University Health Sciences Center. Division of Reproductive’s Genetics, Fetal Medicine and Ultrasound. Department of Obstetrics and Gynecology. 1400 Coulter. Amarillo, TX 79106. Estados Unidos
, L. Ortiza, J.A. Claveroa, C. de Leónb, J. Santolaya-Forgasb
a Departamento de Obstetricia y Ginecología. Hospital General Universitario Gregorio Marañón. Madrid. España
b Facultad de Medicina. Universidad de la Laguna. Santa Cruz de Tenerife. España
c Division of Reproductive’s Genetics. Fetal Medicine and Ultrasound. Texas Tech University. Texas. Estados Unidos
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Resumen

Los avances en los equipos ecográficos y la realización de técnicas invasivas durante el primer trimestre del embarazo han permitido un acercamiento sin precedentes al entendimiento del desarrollo embrionario. Durante el primer trimestre del embarazo, el análisis de las muestras procedentes de suero materno, celoma extraembrionario, saco vitelino y saco amniótico, obtenidas tanto en humanos como en modelos animales, han puesto de manifiesto los cambios sucesivos que se producen en las características fisicoquímicas de estos líquidos en respuesta al desarrollo del propio embrión y sus anejos.

Palabras Clave:
Ecografía transvaginal
Saco vitelino
Celoma extraembrionario
Celocentesis
Abstract

Advances in ultrasonographic equipment and the use of invasive techniques in the first trimester of pregnancy have allowed unprecedented knowledge of embryo development. In the first trimester of pregnancy, analysis of samples from maternal serum, extraembryonic celom, vitelline sac and amniotic sac both from humans and from animal models have revealed the successive changes in the physiochemical characteristics of these fluids in response to the development of the fetus and the extraembryonic compartments.

Key words:
Transvaginal ultrasound
Vitelline sac
Extraembryonic celom
Celocentesis
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Bibliografía
[1.]
T.J. Pereda, P.M. Motta.
New advances in human embryology:morphofunctional relationship between the embryo and the yolk sac.
Med Electron Microsc, 32 (1999), pp. 67-78
[2.]
W.P. Luckett.
Origin and differentiation of the yolk sac and extraembryonic mesoderm in presomite human and rhesus monkey embryos.
Am J Anat, 152 (1978), pp. 59-97
[3.]
W.P. Luckett.
The development of primordial and definitive amniotic cavities in early Rhesus monkey and human embryos.
Am J Anat, 144 (1975), pp. 149-167
[4.]
P. Jeanty, P. Renoy, J. Van Kerkem, J. Dagnelie, J. Struyven.
Ultrasonic demonstration of the amnion.
J Ultrasound Med, 1 (1982), pp. 243-247
[5.]
J. Santolaya-Forgas, J. De León-Luis, R.L. D’Ancona, J. Morgan, R.P. Kauffman.
Evolution of the amniotic sac and extracelomic space as seen by early ultrasound examination.
Fetal Diagn Ther, 18 (2003), pp. 262-269
[6.]
J. Santolaya-Forgas, S. Vengalil, W. Meyer, J. Fortman.
Transvaginal ultrasonographic (TVS) evaluation of baboon gestation from 37-62 days postconception.
[7.]
A. Weissman, J. Itskovitz-Eldor, P. Jakobi.
Sonographic measurement of amniotic fluid volume in the first trimester of pregnancy.
J Ultrasound Med, 15 (1996), pp. 771-774
[8.]
G.J. Burton, J. Hempstock, E. Jauniaux.
Nutrition of the human fetus during the first trimester—a review.
Placenta, 22 (2001), pp. S70-S77
[9.]
D.W. Bianchi, L.E. Wilkins-Haug, A.C. Enders, E.D. Hay.
Origin of extraembryonic mesoderm in experimental animals:relevance to chorionic mosaicism in humans.
Am J Med Genet, 46 (1993), pp. 542-550
[10.]
C.J. Jones, E. Jauniaux.
Ultrastructure of the materno-embryonic interface in the first trimester of pregnancy.
Micron, 26 (1995), pp. 145-173
[11.]
J. Santolaya-Forgas, S. Vengalil, A. Kushwaha, A. Bieniarz, J. Fortman.
Assessment of the risk of fetal loss after the coelocentesis procedure using a baboon model.
Fetal Diagn Ther, 13 (1998), pp. 257-260
[12.]
E. Jauniaux, B. Gulbis, D. Jurkovic, S. Campbell, W.P. Collins, H.A. Ooms.
Relationship between protein concentrations in embryological fluids and maternal serum and yolk sac size during human early pregnancy.
Hum Reprod, 9 (1994), pp. 161-166
[13.]
A.K. Karabulut, R. Layfield, M.K. Pratten.
Growth-promoting effects of different fractions of extra-embryonic coelomic fluid on embryonic development.
Anat Histol Embryol, 29 (2000), pp. 225-234
[14.]
H. Hesseldahl, J.F. Larsen.
Ultrastructure of human yolk sac:endoderm, mesenchyme, tubules and mesothelium.
Am J Anat, 126 (1969), pp. 315-335
[15.]
A.W. Flake, E.D. Zanjani.
In utero hematopoietic stem cell transplantation:ontogenic opportunities and biologic barriers.
Blood, 94 (1999), pp. 2179-2191
[16.]
A. Huyhn, M. Dommergues, B. Izac, L. Croisille, A. Katz, W. Vainchenker, et al.
Characterization of hematopoietic progenitors from human yolk sacs and embryos.
Blood, 86 (1995), pp. 4474-4485
[17.]
F. González-Crussi, L.M. Roth.
The human yolk sac and yolk sac carcinoma. An ultrastructural study.
Hum Pathol, 7 (1976), pp. 675-691
[18.]
T. Takashina.
Haemopoiesis in the human yolk sac.
J Anat, 151 (1987), pp. 125-135
[19.]
A. Kurjak, S. Kupesic, L. Kostovic.
Vascularization of yolk sac and vitelline duct in normal pregnancies studied by transvaginal color and pulsed Doppler.
J Perinat Med, 22 (1994), pp. 433-440
[20.]
A. Kurjak, S. Kupesic, M. Kos.
Three-dimensional sonography for assessment of morphology and vascularization of the fetus and placenta.
J Soc Gynecol Investig, 9 (2002), pp. 186-202
[21.]
G.J. Burton, E. Jauniaux, A.L. Watson.
Maternal arterial connections to the placental intervillous space during the first trimester of human pregnancy:the Boyd collection revisited.
Am J Obstet Gynecol, 181 (1999), pp. 718-724
[22.]
M. Castellucc, G. Kosanke, F. Verdenelli, B. Huppertz, P. Kaufmann.
Villous sprouting:fundamental mechanisms of human placental development.
Hum Reprod Update, 6 (2000), pp. 485-494
[23.]
E. Jauniaux, G.J. Burton, G.J. Moscoso, J. Hustin.
Development of the early human placenta:a morphometric study.
Placenta, 12 (1991), pp. 269-276
[24.]
I. Goldstein, E.A. Zimmer, A. Tamir, B.A. Peretz, E. Paldi.
Evaluation of normal gestational sac growth:appearance of embryonic heartbeat and embryo body movements using the transvaginal technique.
Obstet Gynecol, 77 (1991), pp. 885-888
[25.]
D. Jurkovic, K. Gruboeck, S. Campbell.
Ultrasound features of normal early pregnancy development.
Curr Opin Obstet Gynecol, 7 (1995), pp. 493-504
[26.]
M. Mantoni, J.F. Pedersen.
Ultrasound visualization of the human yolk sac.
J Clin Ultrasound, 7 (1979), pp. 459-460
[27.]
E. Sauerbrei, P.L. Cooperberg, B.J. Poland.
Ultrasound demonstration of the normal fetal yolk sac.
J Clin Ultrasound, 8 (1980), pp. 217-220
[28.]
E. Mara, G.S. Foster.
Spontaneous regression of a yolk sac associated with embryonic death.
J Ultrasound Med, 19 (2000), pp. 655-656
[29.]
K. Makikallio, A. Tekay, P. Jouppila.
Yolk sac and umbilicoplacental hemodynamics during early human embryonic development.
Ultrasound Obstet Gynecol, 14 (1999), pp. 175-179
[30.]
C. Stampone, M. Nicotra, C. Muttinelli, E.V. Cosmi.
Transvaginal sonography of the yolk sac in normal and abnormal pregnancy.
[31.]
F. Figueras, M. Torrents, A. Muñoz, C. Comas, E. Antolin, M. Echevarria, et al.
Three-dimensional yolk and gestational sac volume. A prospective study of prognostic value.
J Reprod Med, 48 (2003), pp. 252-256
[32.]
C.S. Levi, E.A. Lyons, D.J. Lindsay.
Early diagnosis of nonviable pregnancy with endovaginal US.
Radiology, 167 (1988), pp. 383-385
[33.]
E. Jauniaux, D. Jurkovic, Y. Henriet, F. Rodesch, J. Hustin.
Development of the secondary human yolk sac:correlation of sonographic and anatomical features.
Hum Reprod, 6 (1991), pp. 1160-1166
[34.]
S. Kupesic, A. Kurjak.
Volume and vascularity of the yolk sac assessed by three-dimensional and power Doppler ultrasound.
Early Pregnancy, 5 (2001), pp. 40-41
[35.]
J. Campbell, N. Wathen, G. Perry, S. Soneji, N. Sourial, T. Chard.
The coelomic cavity:an important site of materno-fetal nutrient exchange in the first trimester of pregnancy.
Br J Obstet Gynaecol, 100 (1993), pp. 765-767
[36.]
H.P. Robinson.
“Gestation sac” volumes as determined by sonar in the first trimester of pregnancy.
Br J Obstet Gynaecol, 82 (1975), pp. 100-107
[37.]
S. Blackburn, D. Loper.
Maternal, fetal, and neonatal physiology:a clinical perspective, 2nd,
[38.]
B. Gulbis, E. Jauniaux, D. Jurkovic, C. Gervy, H.A. Ooms.
Biochemical investigation of fetal renal maturation in early pregnancy.
Pediatr Res, 39 (1996), pp. 731-735
[39.]
M. Nagamani, P.G. McDonough, J.O. Ellegood, VB. Mahesh.
Maternal and amniotic fluid steroids throughout human pregnancy.
Am J Obstet Gynecol, 134 (1979), pp. 674-680
[40.]
M.I. Evans, A. Drugan, F.C. Koppitch, I.E. Zador, A.J. Sacks, R.J. Sokol.
Genetic diagnosis in the first trimester:the norm for the 1990s.
Am J Obstet Gynecol, 160 (1989), pp. 1332-1336
[41.]
N.C. Wathen, P.L. Cass, D.J. Campbell, M.J. Kitau, T. Chard.
Early amniocentesis:alphafetoprotein levels in amniotic fluid, extraembryonic coelomic fluid and maternal serum between 8 and 13 weeks.
Br J Obstet Gynaecol, 98 (1991), pp. 866-870
[42.]
P.W. Soothill, K.H. Nicolaides, C.H. Rodeck, S. Campbell.
Amniotic fluid and fetal tissues are not heated by obstetric ultrasound scanning.
Br J Obstet Gynaecol, 94 (1987), pp. 675-677
[43.]
G. Makrydimas, A. Kaponis, C. Skentou, D. Lolis.
Short-term safety of celocentesis for the mother and the fetus.
Ultrasound Obstet Gynecol, 19 (2002), pp. 243-245
[44.]
E. Jauniaux, V. Cirigliano, M. Adinolfi.
Very early prenatal diagnosis on coelomic cells using quantitative fluorescent polymerase chain reaction.
Reprod Biomed Online, 6 (2003), pp. 494-498
[45.]
D.G. Cruger, G. Bruun-Petersen, S. Kolvraa.
Turner’s syndrome 45,X found by coelocentesis.
Prenat Diagn, 17 (1997), pp. 588-589
[46.]
D. Jurkovic, E. Jauniaux, S. Campbell, M. Mitchell, C. Lees, M. Layton.
Detection of sickle gene by coelocentesis in early pregnancy:a new approach to prenatal diagnosis of single gene disorders.
Hum Reprod, 10 (1995), pp. 1287-1289
[47.]
G. Makrydimas, I. Georgiou, V. Kranas, K. Zikopoulos, D. Lolis.
Prenatal diagnosis of beta-thalassaemia by coelocentesis.
Mol Hum Reprod, 3 (1997), pp. 729-731
[48.]
J. Santolaya-Forgas, J. Duval, C. Prespin, S. Vengalil, A. Kushwaha, L. Wilson, et al.
Extracoelomic fluid osmometry and electrolyte composition during early gestation in the baboon.
Am J Obstet Gynecol, 179 (1998), pp. 1124-1127
[49.]
G.J. Burton, A.L. Watson, J. Hempstock, J.N. Skepper, E. Jauniaux.
Uterine glands provide histiotrophic nutrition for the human fetus during the first trimester of pregnancy.
J Clin Endocrinol Metab, 87 (2002), pp. 2954-2959
[50.]
J. Campbell, N. Wathen, M. Macintosh, P. Cass, T. Chard, R. Mainwaring Burton.
Biochemical composition of amniotic fluid and extraembryonic coelomic fluid in the first trimester of pregnancy.
Br J Obstet Gynaecol, 99 (1992), pp. 563-565
[51.]
E. Jauniaux, B. Gulbis.
Fluid compartments of the embryonic environment.
Hum Reprod Update, 6 (2000), pp. 268-278
[52.]
G. Atkinson, D.J. Campbell, M.L. Cawood, R.E. Oakey.
Steroids in human intrauterine fluids of early pregnancy.
Clin Endocrinol (Oxf), 44 (1996), pp. 435-440
[53.]
E. Jauniaux, B. Gulbis, D. Jurkovic, J.P. Schaaps, S. Campbell, S. Meuris.
Protein and steroid levels in embryonic cavities in early human pregnancy.
Hum Reprod, 8 (1993), pp. 782-787
[54.]
R.P. Steegers-Theunissen, N.C. Wathen, T.K. Eskes, B. Van Raaij-Selten, T. Chard.
Maternal and fetal levels of methionine and homocysteine in early human pregnancy.
Br J Obstet Gynaecol, 104 (1997), pp. 20-24
[55.]
E. Jauniaux, R.A. Sherwood, D. Jurkovic, F.G. Boa, S. Campbell.
Amino acid concentrations in human embryological fluids.
Hum Reprod, 9 (1994), pp. 1175-1179
[56.]
N.A. Martina, E. Kim, U. Chitkara, N.C. Wathen, T. Chard, L.C. Giudice.
Gestational age-dependent expression of insulin-like growth factor-binding protein-1 (IGFBP-1) phosphoisoforms in human extraembryonic cavities, maternal serum, and decidua suggests decidua as the primary source of IGFBP-1 in these fluids during early pregnancy.
J Clin Endocrinol Metab, 82 (1997), pp. 1894-1898
[57.]
L.D. Nonoshita, N.C. Wathen, B.A. Dsupin, T. Chard, L.C. Giudice.
Insulin-like growth factors (IGFs), IGF-binding proteins (IGFBPs), and proteolyzed IGFBP-3 in embryonic cavities in early human pregnancy:their potential relevance to maternalembryonic and fetal interactions.
J Clin Endocrinol Metab, 79 (1994), pp. 1249-1255
[58.]
J.P. Miell, E. Jauniaux, K.S. Langford, M. Westwood, A. White, J.S. Jones.
Insulin-like growth factor binding protein concentration and post-translational modification in embryological fluid.
Mol Hum Reprod, 3 (1997), pp. 343-349
[59.]
A.K. Karabulut, R. Layfield, M.K. Pratten.
Growth promoting effects of human placental lactogen during early organogenesis:a link to insulin-like growth factors.
J Anat, 198 (2001), pp. 651-662
[60.]
D. Gitlin, A. Perricelli.
Synthesis of serum albumin, prealbumin, alpha-foetoprotein, alpha-1-antitrypsin and transferrin by the human yolk sac.
Nature, 228 (1970), pp. 995-997
[61.]
W.K. Shi, B. Hopkins, S. Thompson, J.K. Heath, B.M. Luke, C.F. Graham.
Synthesis of apolipoproteins, alphafoetoprotein, albumin, and transferrin by the human foetal yolk sack and other foetal organs.
J Embryol Exp Morphol, 85 (1985), pp. 191-206
[62.]
B. Gulbis, E. Jauniaux, F. Cotton, P. Stordeur.
Protein and enzyme patterns in the fluid cavities of the first trimester gestational sac:relevance to the absorptive role of secondary yolk sac.
Mol Hum Reprod, 4 (1998), pp. 857-862
[63.]
B. Contempre, E. Jauniaux, R. Calvo, D. Jurkovic, S. Campbell, G.M. De Escobar.
Detection of thyroid hormones in human embryonic cavities during the first trimester of pregnancy.
J Clin Endocrinol Metab, 77 (1993), pp. 1719-1722
[64.]
R.M. Calvo, E. Jauniaux, B. Gulbis, M. Asuncion, C. Gervy, B. Contempre, et al.
Fetal tissues are exposed to biologically relevant free thyroxine concentrations during early phases of development.
J Clin Endocrinol Metab, 87 (2002), pp. 1768-1777
[65.]
K.M. Moritz, G.B. Lim, E.M. Wintour.
Developmental regulation of erythropoietin and erythropoiesis.
Am J Physiol, 273 (1997), pp. R1829-R1844
[66.]
J. Campbell, N. Wathen, M. Lewis, H. Fingerova, T. Chard.
Erythropoietin levels in amniotic fluid and extraembryonic coelomic fluid in the first trimester of pregnancy.
Br J Obstet Gynaecol, 99 (1992), pp. 974-976
[67.]
E. Jauniaux, D. Jurkovic, B. Gulbis, C. Liesnard, C. Lees, S. Campbell.
Materno-fetal immunoglobulin transfer and passive immunity during the first trimester of human pregnancy.
Hum Reprod, 10 (1995), pp. 3297-3300
[68.]
D. Gitlin, A. Biasucci.
Development of gamma G, gamma A, gamma M, beta IC-beta IA, C 1 esterase inhibitor, ceruloplasmin, transferrin, hemopexin, haptoglobin, fibrinogen, plasminogen, alpha 1-antitrypsin, orosomucoid, beta-lipoprotein, alpha 2-macroglobulin, and prealbumin in the human conceptus.
J Clin Invest, 48 (1969), pp. 1433-1446

Este trabajo ha sido financiado por el Amarillo Women’s Health Research Institute, Texas Tech University. El Dr. Juan Antonio de León Luis es actualmente becario del Fondo de Investigación Sanitaria (BEFI 02/9305)

Copyright © 2004. Sociedad Española de Ginecología y Obstetricia
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