Información del artículo
Resumen
Se presenta un caso de hemorragia intraventricular fetal, diagnosticada a las 28 semanas de gestación y debida a resistencia a la proteína C activada por factor V Leiden. Describimos los factores de riesgo maternos y fetales asociados a la HIV así como su evolución ecográfica.
Palabras clave:
Hemorragia intraventricular fetal
Factor V Leiden
Resistencia a la proteína C activada
Abstract
We present a case of fetal intraventricular hemorrhage diagnosed at week 28 of gestation. The cause was resistance to activated protein C due to factor V Leiden. We describe the maternal and fetal risk factors associated with intraventricular hemorrhage, as well as sonographic findings.
Key Words:
Fetal intraventricular hemorrhage
Factor V Leiden
Resistance to activated protein C
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Bibliografía
[1.]
M. Casellas.
Trombofilias (hereditarias y adquiridas) y embarazo.
Folia Clínica en Obstetricia y Ginecología, 37 (2003), pp. 9-46
[2.]
H. Bagán, M. Casellas, J. Sagalá, M.J. Cerqueira, L. Cabero.
RCIR y FV Leiden.
Folia Clínica en Obstetricia y Ginecología, 37 (2003), pp. 50-53
[3.]
U. Seligsohn, A. Lubetsky.
Genetic susceptibility to venous thrombosis.
N Engl J Med, 344 (2001), pp. 1222-1231
[4.]
D.M. Sherer, A. Anyaegbunam, C. Onyeije.
Antepartum fetal intracranial hemorrhage, predisposing factors and prenatal sonography: a review.
Am J Perinatol, 15 (1998), pp. 431-439
[5.]
P. Vergani, N. Strobelt, A. Locatelli, G. Paterlini, P. Tagliabue, E. Parravicini, et al.
Clinical significance of fetal intracranial hemorrhage.
Am J Obstet Gynecol, 175 (1996), pp. 536-542
[6.]
J. Petaja, L. Hiltunen, V. Fellman.
Increased risk of intraventricular hemorrhage in preterm infants with thrombophilia.
Pediatr Res, 49 (2001), pp. 643-646
[7.]
S. Aronis, H. Bouza, H. Pergantou, Z. Kapsimalis, H. Platokouki, M. Xanthou.
Prothrombotic factors in neonates with cerebral thrombosis and intraventricular hemorrhage.
Acta Paediatr Suppl, 438 (2002), pp. 87-91
[8.]
A. Groothuis, M. Kleine, S. Guid.
Intraventricular haemorrhage in utero. A case-report and review of the literature.
Eur J Obstet Gynecol Reprod Biol, 89 (2000), pp. 207-211
[9.]
C. Fusch, C. Ozdoba, P. Kuhn, P. Durig, L. Remonda, C. Muller, et al.
Perinatal ultrasonography and magnetic resonance imaging findings en congenital hydrocephalus associated with fetal intraventricular hemorrhage.
Am J Obstet Gynecol, 177 (1997), pp. 512-517
[10.]
I. Bombi, J.M. Boguñá, M. Toll, et al.
Hemorragia intraventricular fetal debida a una púrpura trombocitopénica idiopática materna.
Prog Obstet Ginecol, 45 (2002), pp. 497-499
[11.]
H. Roqué, M. Paidas, A. Rebarber, J. Maturi, L. O’Neill, E. Kuczynski, et al.
There is no association between maternal thombophilia and recurrent first-trimester loss.
Am J Obstet Gynecol, 184 (2001), pp. S15
[12.]
P. Clark, S. Twaddle, I.D. Walker, L. Scott, I.A. Greer.
Cost-effectiveness of screening for the factor V Leiden mutation in pregnant women.
Lancet, 359 (2002), pp. 1919-1920
[13.]
American College of Obstetrics and Gynecology.
Clinical management guidelines for obstetrician-gynaecologists. ACOG Practice Bulletin.
Obstet Gynecol, 19 (2000), pp. 1-10
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