metricas
covid
Buscar en
Radiología
Toda la web
Inicio Radiología Enfermedad de Cowden: presentación de un caso y revisión de la bibliografía*
Información de la revista

Estadísticas

Siga este enlace para acceder al texto completo del artículo

Enfermedad de Cowden: presentación de un caso y revisión de la bibliografía*
Cowden disease: report of a case and review of the bibliography
Rafael Vicente,1, Juan A. García-Gutiérrez1, Joaquín Mut2, Beatriz Asenjo1
1 Servicio de Radiodiagnóstico.
2 Servicio de Dermatología. Hospital Comarcal de la Axarquia. Málaga.
Leído
1246
Veces
se ha leído el artículo
1045
Total PDF
201
Total HTML
Compartir estadísticas
 array:23 [
  "pii" => "S0033833801769214"
  "issn" => "00338338"
  "doi" => "10.1016/S0033-8338(01)76921-4"
  "estado" => "S300"
  "fechaPublicacion" => "2001-01-01"
  "aid" => "76921"
  "copyright" => "Sociedad Española de Radiología Médica (SERAM) and Elsevier España, S.L."
  "copyrightAnyo" => "2001"
  "documento" => "article"
  "crossmark" => 0
  "subdocumento" => "fla"
  "cita" => "Radiologia. 2001;43:38-41"
  "abierto" => array:3 [
    "ES" => false
    "ES2" => false
    "LATM" => false
  ]
  "gratuito" => false
  "lecturas" => array:2 [
    "total" => 727
    "formatos" => array:3 [
      "EPUB" => 6
      "HTML" => 187
      "PDF" => 534
    ]
  ]
  "itemSiguiente" => array:18 [
    "pii" => "S0033833801769226"
    "issn" => "00338338"
    "doi" => "10.1016/S0033-8338(01)76922-6"
    "estado" => "S300"
    "fechaPublicacion" => "2001-01-01"
    "aid" => "76922"
    "copyright" => "Sociedad Española de Radiología Médica (SERAM) and Elsevier España, S.L."
    "documento" => "article"
    "crossmark" => 0
    "subdocumento" => "fla"
    "cita" => "Radiologia. 2001;43:42-6"
    "abierto" => array:3 [
      "ES" => false
      "ES2" => false
      "LATM" => false
    ]
    "gratuito" => false
    "lecturas" => array:2 [
      "total" => 518
      "formatos" => array:3 [
        "EPUB" => 8
        "HTML" => 175
        "PDF" => 335
      ]
    ]
    "es" => array:10 [
      "idiomaDefecto" => true
      "titulo" => "Condrosarcoma del hioides&#58; hallazgos en tomograf&#237;a computarizada<a class="elsevierStyleCrossRef" href="#fn0005">&#42;</a>"
      "tienePdf" => "es"
      "tieneTextoCompleto" => 0
      "tieneResumen" => array:2 [
        0 => "es"
        1 => "en"
      ]
      "paginas" => array:1 [
        0 => array:2 [
          "paginaInicial" => "42"
          "paginaFinal" => "46"
        ]
      ]
      "titulosAlternativos" => array:1 [
        "en" => array:1 [
          "titulo" => "Chondrosarcoma of the hyoid bone&#58; computed tomography findings"
        ]
      ]
      "contieneResumen" => array:2 [
        "es" => true
        "en" => true
      ]
      "contienePdf" => array:1 [
        "es" => true
      ]
      "autores" => array:1 [
        0 => array:2 [
          "autoresLista" => "Julio S&#225;ez, Juan Antonio Gallego, Mar&#237;a Jos&#233; Fuster"
          "autores" => array:3 [
            0 => array:2 [
              "nombre" => "Julio"
              "apellidos" => "S&#225;ez"
            ]
            1 => array:2 [
              "nombre" => "Juan Antonio"
              "apellidos" => "Gallego"
            ]
            2 => array:2 [
              "nombre" => "Mar&#237;a Jos&#233;"
              "apellidos" => "Fuster"
            ]
          ]
        ]
      ]
    ]
    "idiomaDefecto" => "es"
    "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0033833801769226?idApp=UINPBA00004N"
    "url" => "/00338338/0000004300000001/v1_201307311024/S0033833801769226/v1_201307311024/es/main.assets"
  ]
  "itemAnterior" => array:18 [
    "pii" => "S0033833801769202"
    "issn" => "00338338"
    "doi" => "10.1016/S0033-8338(01)76920-2"
    "estado" => "S300"
    "fechaPublicacion" => "2001-01-01"
    "aid" => "76920"
    "copyright" => "Sociedad Espa&#241;ola de Radiolog&#237;a M&#233;dica &#40;SERAM&#41; and Elsevier Espa&#241;a&#44; S&#46;L&#46;"
    "documento" => "article"
    "crossmark" => 0
    "subdocumento" => "fla"
    "cita" => "Radiologia. 2001;43:35-7"
    "abierto" => array:3 [
      "ES" => false
      "ES2" => false
      "LATM" => false
    ]
    "gratuito" => false
    "lecturas" => array:2 [
      "total" => 377
      "formatos" => array:3 [
        "EPUB" => 9
        "HTML" => 136
        "PDF" => 232
      ]
    ]
    "es" => array:10 [
      "idiomaDefecto" => true
      "titulo" => "Tumor estromal intestinal&#46; Necrosis aguda liquefactiva<a class="elsevierStyleCrossRef" href="#fn0005">&#42;</a>"
      "tienePdf" => "es"
      "tieneTextoCompleto" => 0
      "tieneResumen" => array:2 [
        0 => "es"
        1 => "en"
      ]
      "paginas" => array:1 [
        0 => array:2 [
          "paginaInicial" => "35"
          "paginaFinal" => "37"
        ]
      ]
      "titulosAlternativos" => array:1 [
        "en" => array:1 [
          "titulo" => "Gastrointestinal stromal tumor&#58; acute liquefaction necrosis"
        ]
      ]
      "contieneResumen" => array:2 [
        "es" => true
        "en" => true
      ]
      "contienePdf" => array:1 [
        "es" => true
      ]
      "autores" => array:1 [
        0 => array:2 [
          "autoresLista" => "Luis L&#243;pez-Negrete, Jorge G&#46; Lozano, J&#46; Luis S&#225;nchez, Julio Sala"
          "autores" => array:4 [
            0 => array:2 [
              "nombre" => "Luis"
              "apellidos" => "L&#243;pez-Negrete"
            ]
            1 => array:2 [
              "nombre" => "Jorge G&#46;"
              "apellidos" => "Lozano"
            ]
            2 => array:2 [
              "nombre" => "J&#46;"
              "apellidos" => "Luis S&#225;nchez"
            ]
            3 => array:2 [
              "nombre" => "Julio"
              "apellidos" => "Sala"
            ]
          ]
        ]
      ]
    ]
    "idiomaDefecto" => "es"
    "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0033833801769202?idApp=UINPBA00004N"
    "url" => "/00338338/0000004300000001/v1_201307311024/S0033833801769202/v1_201307311024/es/main.assets"
  ]
  "es" => array:15 [
    "idiomaDefecto" => true
    "titulo" => "Enfermedad de Cowden&#58; presentaci&#243;n de un caso y revisi&#243;n de la bibliograf&#237;a<a class="elsevierStyleCrossRef" href="#fn0005">&#42;</a>"
    "tieneTextoCompleto" => 0
    "paginas" => array:1 [
      0 => array:2 [
        "paginaInicial" => "38"
        "paginaFinal" => "41"
      ]
    ]
    "autores" => array:1 [
      0 => array:4 [
        "autoresLista" => "Rafael Vicente, Juan A&#46; Garc&#237;a-Guti&#233;rrez, Joaqu&#237;n Mut, Beatriz Asenjo"
        "autores" => array:4 [
          0 => array:3 [
            "nombre" => "Rafael"
            "apellidos" => "Vicente"
            "referencia" => array:2 [
              0 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">&#8224;</span>"
                "identificador" => "cor0005"
              ]
              1 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">1</span>"
                "identificador" => "aff0005"
              ]
            ]
          ]
          1 => array:3 [
            "nombre" => "Juan A&#46;"
            "apellidos" => "Garc&#237;a-Guti&#233;rrez"
            "referencia" => array:1 [
              0 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">1</span>"
                "identificador" => "aff0005"
              ]
            ]
          ]
          2 => array:3 [
            "nombre" => "Joaqu&#237;n"
            "apellidos" => "Mut"
            "referencia" => array:1 [
              0 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">2</span>"
                "identificador" => "aff0010"
              ]
            ]
          ]
          3 => array:3 [
            "nombre" => "Beatriz"
            "apellidos" => "Asenjo"
            "referencia" => array:1 [
              0 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">1</span>"
                "identificador" => "aff0005"
              ]
            ]
          ]
        ]
        "afiliaciones" => array:2 [
          0 => array:3 [
            "entidad" => "<span class="elsevierStyleItalic">Servicio de Radiodiagn&#243;stico&#46;</span>"
            "etiqueta" => "<span class="elsevierStyleSup">1</span>"
            "identificador" => "aff0005"
          ]
          1 => array:3 [
            "entidad" => "<span class="elsevierStyleItalic">Servicio de Dermatolog&#237;a&#46; Hospital Comarcal de la Axarquia&#46; M&#225;laga&#46;</span>"
            "etiqueta" => "<span class="elsevierStyleSup">2</span>"
            "identificador" => "aff0010"
          ]
        ]
        "correspondencia" => array:1 [
          0 => array:3 [
            "identificador" => "cor0005"
            "etiqueta" => "&#8224;"
            "correspondencia" => "Correspondencia&#58; RAFAEL VICENTE TRIGUEROS&#46; Tom&#225;s Escalonilla&#44; 5-5&#46;<span class="elsevierStyleSup">o</span>C&#46; 29010 M&#225;laga&#46;"
          ]
        ]
      ]
    ]
    "titulosAlternativos" => array:1 [
      "en" => array:1 [
        "titulo" => "Cowden disease&#58; report of a case and review of the bibliography"
      ]
    ]
    "pdfFichero" => "main.pdf"
    "tienePdf" => true
    "fechaRecibido" => "2000-10-31"
    "fechaAceptado" => "2001-01-11"
    "PalabrasClave" => array:2 [
      "es" => array:1 [
        0 => array:4 [
          "clase" => "keyword"
          "titulo" => "Palabras clave"
          "identificador" => "xpalclavsec226956"
          "palabras" => array:3 [
            0 => "Enfermedad de Cowden"
            1 => "Poliposis gastrointestinal"
            2 => "Hamartomas"
          ]
        ]
      ]
      "en" => array:1 [
        0 => array:4 [
          "clase" => "keyword"
          "titulo" => "Key words"
          "identificador" => "xpalclavsec226955"
          "palabras" => array:3 [
            0 => "Cowden disease"
            1 => "Gastrointestinal polyposis"
            2 => "Hamartomas"
          ]
        ]
      ]
    ]
    "tieneResumen" => true
    "resumen" => array:2 [
      "es" => array:2 [
        "titulo" => "Resumen"
        "resumen" => "<p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">La Enfermedad de Cowden &#40;EC&#41;&#44; tambi&#233;n conocida como &#171;S&#237;ndrome de Neoplasias-Hamartomas M&#250;ltiples&#187;&#44; es una rara e infra-diagnosticada entidad hereditaria autos&#243;mica dominante caracterizada por la presencia de m&#250;ltiples hamartomas de origen mesod&#233;rmico&#44; en-dod&#233;rmico y ectod&#233;rmico&#44; as&#237; como por una alta incidencia de presen-taci&#243;n de tumores malignos&#46; Actualmente se clasifica como un s&#237;ndro-me preneopl&#225;sico hereditario&#46;</p><p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">Describimos los hallazgos en un paciente con EC con especial &#233;nfasis sobre los aspectos de imagen&#44; revisando las principales manifesta-ciones de esta entidad&#46;</p>"
      ]
      "en" => array:2 [
        "titulo" => "Abstract"
        "resumen" => "<p id="spar0015" class="elsevierStyleSimplePara elsevierViewall">Cowden diasease &#40;CD&#41;&#44; also known as multiple hamartoma syndrome&#44; is a rare and underdiagnosed autosomal dominant hereditary disorder characterized by the presence of multiple hamartomas originating in mesoderm&#44; endoderm and ectoderm&#44; and is associated with a hight incidence of malignant tumor development&#46; It is presently considered a hereditary preneoplastic syndrome&#46;</p><p id="spar0020" class="elsevierStyleSimplePara elsevierViewall">We report the our observations in a patient with CD&#44; ocusing especially on the findings in imaging studies&#44; and review the major features of this entity&#46;</p>"
      ]
    ]
    "NotaPie" => array:1 [
      0 => array:2 [
        "etiqueta" => "&#42;"
        "nota" => "<p class="elsevierStyleNotepara">Vicente R&#44; Garc&#237;a-Guti&#233;rrez Juan A&#44; Mut J&#44; et al&#46; Enfermedad de Cowden&#58; presentaci&#243;n de un caso y revisi&#243;n de la bibliograf&#237;a&#46; Radiolog&#237;a 2001&#59;43&#40;1&#41;&#58;38-41&#46;</p>"
      ]
    ]
    "bibliografia" => array:2 [
      "titulo" => "Bibliograf&#237;a"
      "seccion" => array:1 [
        0 => array:2 [
          "identificador" => "bibs0005"
          "bibliografiaReferencia" => array:17 [
            0 => array:3 [
              "identificador" => "bib0005"
              "etiqueta" => "1&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Cowden&#8217;s disease"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:2 [
                            0 => "K&#46;M&#46; Lloyd"
                            1 => "M&#46; Dennis"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "Ann Intern Med"
                        "fecha" => "1963"
                        "volumen" => "48"
                        "paginaInicial" => "136"
                        "paginaFinal" => "142"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            1 => array:3 [
              "identificador" => "bib0010"
              "etiqueta" => "2&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Cowden&#8217;s disease &#40;Multiple hamartoma and neoplasm syndrome"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:2 [
                            0 => "O&#46;S&#46; Salem"
                            1 => "W&#46;D&#46; Steck"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "J Am Acad Dermatol"
                        "fecha" => "1983"
                        "volumen" => "8"
                        "paginaInicial" => "686"
                        "paginaFinal" => "696"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/6863628"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            2 => array:3 [
              "identificador" => "bib0015"
              "etiqueta" => "3&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Cowden&#8217;s disease&#46; Analysis the fourteen new cases"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:1 [
                            0 => "T&#46;M&#46; Starvink"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "J Am Acad Dermatol"
                        "fecha" => "1984"
                        "volumen" => "11"
                        "paginaInicial" => "1127"
                        "paginaFinal" => "1141"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/6512057"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            3 => array:3 [
              "identificador" => "bib0020"
              "etiqueta" => "4&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Lhermitte-Duclos disease and Cowden disease &#58; a single fhakomatosis"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:4 [
                            0 => "G&#46;W&#46; Padberg"
                            1 => "I&#46;D&#46;L&#46; Schot"
                            2 => "G&#46;J&#46; Vielvoye"
                            3 => "F&#46;C&#46; De Beer"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1002/ana.410290511"
                      "Revista" => array:7 [
                        "tituloSerie" => "Ann Neurol"
                        "fecha" => "1991"
                        "volumen" => "29"
                        "paginaInicial" => "517"
                        "paginaFinal" => "523"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/1859181"
                            "web" => "Medline"
                          ]
                        ]
                        "itemHostRev" => array:3 [
                          "pii" => "S0735109706014525"
                          "estado" => "S300"
                          "issn" => "07351097"
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            4 => array:3 [
              "identificador" => "bib0025"
              "etiqueta" => "5&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Recurrent Lhermitte-Duclos Disease&#46; Report of two cases and association with Cowden&#8217;s Disease"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:4 [
                            0 => "D&#46;W&#46; Williams"
                            1 => "A&#46;D&#46; Elster"
                            2 => "L&#46;E&#46; Ginsberg"
                            3 => "C&#46; Stanton"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "AJNR"
                        "fecha" => "1992"
                        "volumen" => "13"
                        "paginaInicial" => "287"
                        "paginaFinal" => "290"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/1595461"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            5 => array:3 [
              "identificador" => "bib0030"
              "etiqueta" => "6&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Cowden Syndrom and Lhermitte-Duclos Disease"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:4 [
                            0 => "S&#46; Albrecht"
                            1 => "R&#46;M&#46; Haber"
                            2 => "J&#46;C&#46; Goodman"
                            3 => "M&#46; Duvic"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Cancer"
                        "fecha" => "1992"
                        "volumen" => "70"
                        "paginaInicial" => "869"
                        "paginaFinal" => "876"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/1643619"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            6 => array:3 [
              "identificador" => "bib0035"
              "etiqueta" => "7&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "The Hamartomatous polipous syndroms&#58; clinical and radiological features"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:3 [
                            0 => "R&#46;K&#46; Harmed"
                            1 => "J&#46;L&#46; Buck"
                            2 => "L&#46;H&#46; Sobin"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.2214/ajr.164.3.7863873"
                      "Revista" => array:6 [
                        "tituloSerie" => "AJR"
                        "fecha" => "1995"
                        "volumen" => "164"
                        "paginaInicial" => "565"
                        "paginaFinal" => "571"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/7863873"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            7 => array:3 [
              "identificador" => "bib0040"
              "etiqueta" => "8&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Regulation of G1 progression by the PTEN tumor supres-sion protein is linked to inhibition of the phosphatidylinositol 3-Kinasa&#47;AKT pathway"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "S&#46; Ramaswamy"
                            1 => "N&#46; Nakamura"
                            2 => "F&#46; Vazquez"
                            3 => "D&#46;B&#46; Batt"
                            4 => "S&#46; Perera"
                            5 => "T&#46;M&#46; Roberts"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Proc Natl Acad Sci USA"
                        "fecha" => "1999"
                        "volumen" => "96"
                        "paginaInicial" => "2110"
                        "paginaFinal" => "2115"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/10051603"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            8 => array:3 [
              "identificador" => "bib0045"
              "etiqueta" => "9&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Novel mutation of the PEN gene in an italian Cowden&#8217;s disease Kindred"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:6 [
                            0 => "S&#46; Scala"
                            1 => "P&#46; Bruini"
                            2 => "Muzio L Lo"
                            3 => "M&#46; Mignogna"
                            4 => "G&#46; Viglietto"
                            5 => "A&#46; Fusco"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Int J Oncol"
                        "fecha" => "1998"
                        "volumen" => "13"
                        "paginaInicial" => "665"
                        "paginaFinal" => "668"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/9735393"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            9 => array:3 [
              "identificador" => "bib0050"
              "etiqueta" => "10&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Bannayan-Riley-Ruvalcaba syndrom&#58; spectrum of intestinal pathology incluiding juvenile polyps"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "A&#46; Lowichik"
                            1 => "F&#46;V&#46; White"
                            2 => "C&#46;F&#46; Timmous"
                            3 => "A&#46;G&#46; Weinberg"
                            4 => "T&#46;S&#46; Gunasekaran"
                            5 => "K&#46; Nathan"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Pediatr Der Pathol"
                        "fecha" => "2000"
                        "volumen" => "3"
                        "paginaInicial" => "155"
                        "paginaFinal" => "161"
                        "itemHostRev" => array:3 [
                          "pii" => "S0735109705021169"
                          "estado" => "S300"
                          "issn" => "07351097"
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            10 => array:3 [
              "identificador" => "bib0055"
              "etiqueta" => "11&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "An Overlap of cowden&#8217;s disease and Bannayan-Riley-Ruvalcaba Syndrome in the same family"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:3 [
                            0 => "J&#46; Perriard"
                            1 => "J&#46;H&#46; Sauvat"
                            2 => "M&#46; Harms"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "J Am Acad Dermatol"
                        "fecha" => "2000"
                        "volumen" => "42"
                        "paginaInicial" => "348"
                        "paginaFinal" => "350"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/10640930"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            11 => array:3 [
              "identificador" => "bib0060"
              "etiqueta" => "12&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Breast cancer in Cowden&#8217;s disease&#58; a case report with review of the literature"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "Y&#46; Tsubosa"
                            1 => "T&#46; Fukutomi"
                            2 => "H&#46; Tsuda"
                            3 => "Y&#46; Kanai"
                            4 => "Akashi-Tanaka"
                            5 => "T&#46; Nanasawa"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "Jpn Clin Oncol"
                        "fecha" => "1998"
                        "volumen" => "28"
                        "paginaInicial" => "42"
                        "paginaFinal" => "46"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            12 => array:3 [
              "identificador" => "bib0065"
              "etiqueta" => "13&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "The Cowden Syndrome&#58; a clinical and genetic study in 21 patients"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:6 [
                            0 => "T&#46;M&#46; Starink"
                            1 => "Veen JW van der"
                            2 => "L&#46;P&#46; De Waal"
                            3 => "G&#46;G&#46; De Lange"
                            4 => "J&#46;J&#46;P&#46; Gille"
                            5 => "A&#46;W&#46; Erikson"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:7 [
                        "tituloSerie" => "Clin Genet"
                        "fecha" => "1986"
                        "volumen" => "29"
                        "paginaInicial" => "222"
                        "paginaFinal" => "233"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/3698331"
                            "web" => "Medline"
                          ]
                        ]
                        "itemHostRev" => array:3 [
                          "pii" => "S0735109703012804"
                          "estado" => "S300"
                          "issn" => "07351097"
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            13 => array:3 [
              "identificador" => "bib0070"
              "etiqueta" => "14&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Histological typing of intestinal tumors&#46; WHO international histological classification of tumours"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:2 [
                            0 => "J&#46;r&#46; Jass"
                            1 => "L&#46;H&#46; Sobin"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "LibroEditado" => array:2 [
                        "edicion" => "2"
                        "serieFecha" => "1989"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            14 => array:3 [
              "identificador" => "bib0075"
              "etiqueta" => "15&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Disseminated hereditary gastrointestinal polyposis with orocutaneus hamartomatosis &#40;Cowden&#8217;s disease&#41;"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:3 [
                            0 => "M&#46; Gorensek"
                            1 => "I&#46; Matko"
                            2 => "A&#46; Skvalormik"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Endoscopy"
                        "fecha" => "1984"
                        "volumen" => "16"
                        "paginaInicial" => "59"
                        "paginaFinal" => "63"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/6714176"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            15 => array:3 [
              "identificador" => "bib0080"
              "etiqueta" => "16&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Cowden disease&#58; report of two additional cases"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:2 [
                            0 => "J&#46;W&#46; Burnett"
                            1 => "R Calton GJ&#46; Goldner"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Br J Dermatol"
                        "fecha" => "1975"
                        "volumen" => "93"
                        "paginaInicial" => "329"
                        "paginaFinal" => "336"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/1191539"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            16 => array:3 [
              "identificador" => "bib0085"
              "etiqueta" => "17&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Diffuse esophageal glycogenic acanthosis&#58; a endoscopic marker of Cowden&#8217;s disease"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:3 [
                            0 => "P&#46;S&#46; Kay"
                            1 => "R&#46;M&#46; Soetikme"
                            2 => "R Young HS&#46; Mindelzum"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:7 [
                        "tituloSerie" => "Am J Gastroenterol"
                        "fecha" => "1997"
                        "volumen" => "92"
                        "paginaInicial" => "1038"
                        "paginaFinal" => "1040"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/9177527"
                            "web" => "Medline"
                          ]
                        ]
                        "itemHostRev" => array:3 [
                          "pii" => "S0735109701018198"
                          "estado" => "S300"
                          "issn" => "07351097"
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
          ]
        ]
      ]
    ]
  ]
  "idiomaDefecto" => "es"
  "url" => "/00338338/0000004300000001/v1_201307311024/S0033833801769214/v1_201307311024/es/main.assets"
  "Apartado" => array:4 [
    "identificador" => "8111"
    "tipo" => "SECCION"
    "es" => array:2 [
      "titulo" => "Comunicaciones breves"
      "idiomaDefecto" => true
    ]
    "idiomaDefecto" => "es"
  ]
  "PDF" => "https://static.elsevier.es/multimedia/00338338/0000004300000001/v1_201307311024/S0033833801769214/v1_201307311024/es/main.pdf?idApp=UINPBA00004N&text.app=https://www.elsevier.es/"
  "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0033833801769214?idApp=UINPBA00004N"
]
Información del artículo
ISSN: 00338338
Idioma original: Español
Datos actualizados diariamente
año/Mes Html Pdf Total
2024 Noviembre 0 1 1
2024 Octubre 0 13 13
2024 Septiembre 0 17 17
2024 Agosto 0 12 12
2024 Julio 0 16 16
2024 Junio 0 17 17
2024 Mayo 0 10 10
2024 Abril 0 13 13
2024 Marzo 0 37 37
2024 Febrero 0 6 6
2024 Enero 0 10 10
2023 Diciembre 0 17 17
2023 Noviembre 6 24 30
2023 Octubre 0 18 18
2023 Septiembre 5 12 17
2023 Agosto 0 7 7
2023 Julio 0 21 21
2023 Junio 0 9 9
2023 Mayo 0 6 6
2023 Abril 0 3 3
2023 Marzo 1 5 6
2023 Febrero 0 13 13
2023 Enero 0 8 8
2022 Diciembre 0 10 10
2022 Noviembre 0 12 12
2022 Octubre 0 7 7
2022 Septiembre 0 18 18
2022 Agosto 0 15 15
2022 Julio 0 6 6
2022 Junio 0 5 5
2022 Mayo 0 14 14
2022 Abril 0 6 6
2022 Marzo 0 11 11
2022 Febrero 0 4 4
2022 Enero 0 3 3
2021 Diciembre 0 8 8
2021 Noviembre 0 3 3
2021 Septiembre 0 2 2
2021 Agosto 0 2 2
2021 Julio 0 1 1
2021 Junio 0 3 3
2021 Mayo 1 4 5
2021 Abril 0 10 10
2021 Marzo 1 5 6
2021 Febrero 0 2 2
2021 Enero 0 5 5
2020 Diciembre 0 4 4
2020 Noviembre 0 3 3
2020 Octubre 0 3 3
2020 Septiembre 0 6 6
2020 Agosto 0 14 14
2020 Julio 0 3 3
2020 Junio 0 7 7
2020 Mayo 0 4 4
2020 Abril 0 1 1
2020 Marzo 0 10 10
2020 Febrero 0 5 5
2020 Enero 1 15 16
2019 Diciembre 0 31 31
2019 Noviembre 0 7 7
2019 Octubre 0 2 2
2019 Septiembre 0 1 1
2019 Agosto 0 8 8
2019 Julio 0 15 15
2019 Junio 0 17 17
2019 Mayo 0 67 67
2018 Junio 0 1 1
2018 Mayo 1 20 21
2018 Abril 6 43 49
2018 Marzo 12 34 46
2018 Febrero 6 18 24
2018 Enero 3 17 20
2017 Diciembre 8 11 19
2017 Noviembre 13 22 35
2017 Octubre 8 18 26
2017 Septiembre 4 15 19
2017 Agosto 3 25 28
2017 Julio 6 25 31
2017 Junio 3 18 21
2017 Mayo 11 17 28
2017 Abril 4 20 24
2017 Marzo 23 30 53
2017 Febrero 11 8 19
2017 Enero 9 6 15
2016 Diciembre 11 2 13
2016 Noviembre 9 7 16
2016 Octubre 19 11 30
2016 Septiembre 11 3 14
2016 Agosto 4 0 4
2016 Julio 1 0 1
Mostrar todo

Siga este enlace para acceder al texto completo del artículo

es en pt

¿Es usted profesional sanitario apto para prescribir o dispensar medicamentos?

Are you a health professional able to prescribe or dispense drugs?

Você é um profissional de saúde habilitado a prescrever ou dispensar medicamentos