Brote psicótico agudo y rabdomiólisis tras el uso de lovastatina

Información del artículo

Resumen

Introducción

Las estatinas son los medicamentos más recetados en el mundo, por el beneficio y la seguridad que ofrecen. Sin embargo, pueden causar reacciones adversas a escala neurológica, gastrointestinal, renal y muscular.

Objetivo

Es describir el curso clínico de una paciente con reacción adversa medicamentosa a la lovastatina.

Métodos

Reporte de caso y revisión de la literatura.

Resultados

Mujer de 52 años con psicosis súbita y rabdomiólisis secundaria al consumo de lovastatina, clínica que remite con la suspensión del fármaco. La relación causal se establece a través de la escala de Naranjo, con puntuación de 6 (probable reacción adversa medicamentosa).

Conclusión

La manifestación simultánea de psicosis y rabdomiólisis representa un caso clínico atípico y único consecuente a la ingesta de lovastatina.

Palabras clave:

Psicosis

rabdomiólisis

lovastatina

reacción adversa medicamentosa

Abstract

Introduction

Statins are the most prescribed drugs worldwide given the benefit and security they offer. However, they can cause severe neurological, gastrointestinal, renal and muscular side effects.

Objective

To describe the clinical course of a female patient with adverse drug reaction to Lovastatin.

Methods

Case report and literature review.

Results

52-year old woman with sudden psychosis and rhabdomyolysis secondary to Lovastatin and ending after the drug suspension. The causal relationship was corroborated with a score of 6 (probable ADR) on Naranjo's Scale.

Conclusions

The simultaneous manifestation of psychosis and rhabdomiolysis represents an atypical and unique case following Lovastatin ingestion.

Key words:

Psychosis

rhabdomyolysis

lovastatin

adverse drug reaction

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