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Inicio Revista Colombiana de Reumatología Epidemiología de la osteoporosis
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Vol. 16. Núm. 1.
Páginas 61-75 (marzo 2009)
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Vol. 16. Núm. 1.
Páginas 61-75 (marzo 2009)
Acceso a texto completo
Epidemiología de la osteoporosis
Epidemiology of osteoporosis
Visitas
23059
Luis Alonso González1,
Autor para correspondencia
luisalonsogonzalez@une.net.com

Correo electrónico:.
, Gloria María Vásquez2, José Fernando Molina3
1 Profesor Sección de Reumatología, Facultad de Medicina, Universidad de Antioquia, Hospital Universitario San Vicente de Paúl. Medellín, Colombia
2 Grupo de Reumatología, Universidad de Antioquia, Grupos de Inmunología celular e inmunogenética. Facultad de Medicina, Universidad de Antioquia. Medellín, Colombia
3 Profesor de Reumatología, Facultad de Medicina, Universidad CES, Medellín, Colombia
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Resumen

La osteoporosis se define como una entidad esquelética caracterizada por baja masa ósea y deterioro de la microarquitectura ósea, lo cual lleva a una mayor fragilidad ósea y riesgo de fractura. Todas las fracturas osteoporóticas aumentan la morbilidad de los pacientes; sin embargo, las fracturas de cadera y vertebrales también están asociadas con una mayor mortalidad. Estas fracturas por fragilidad también son una carga considerable para el sistema de salud y tienen un gran impacto económico. Por lo tanto, el conocimiento de la epidemiología de la enfermedad es fundamental para tratar de desarrollar estrategias que estén orientadas a disminuir esta carga.

Palabras clave:
epidemiología
densidad mineral ósea
osteoporosis
fractura
Summary

Osteoporosis is defined as a systemic skeletal disorder characterized by low bone mass and microarchitectural deterioration of bone tissue, with a consequent increase in bone fragility and susceptibility to fracture. All osteoporotic fractures increase patient morbidity; however, fractures of the hip and vertebrae are also associated with important mortality. These fragility fractures have a considerable burden to health care system and a huge economic impact. Understanding the epidemiology of this disease is therefore necessary in trying to develop strategies to help reduce this load.

Key words:
epidemiology
bone mineral density
osteoporosis
fracture
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Referencias
[1.]
Consensus development Conference, (1993).
Diagnosis, prophylaxis and treatment of osteoporosis.
Am J. Med, 94 (1993), pp. 646-650
[2.]
National Institutes of Health Consensus Development Panel on Osteoporosis Prevention, Diagnosis, and Therapy Consensus Conference.
JAMA, 285 (2001), pp. 785-795
[3.]
J.A. Kanis, L.J. Melton III, C. Christiansen, C.C. Johnston, N. Khaltaev.
The diagnosis of osteoporosis.
J Bone Miner Res, 9 (1994), pp. 1137-1141
[4.]
I.I.J. Melton.
Epidemiology and classification of osteoporosis.
Rheumatology, 4th,
[5.]
E. Stein, E. Shane.
Secondary osteoporosis.
Endocrinol Metab Clin N Am, 32 (2003), pp. 115-134
[6.]
L. Fitzpatrick.
Secondary causes of osteoporosis.
Mayo Clin Proc, 77 (2002), pp. 453-468
[7.]
Z.C. Orlic, L.G. Raisz.
Causes of secondary osteoporosis.
J Clin Densitom, 2 (1999), pp. 79-92
[8.]
K.D. Harper, T.J. Weber.
Secondary osteoporosis: diagnostic considerations.
Endocrinol Metab Clin North Am, 27 (1998), pp. 325-348
[9.]
P. Ebeling.
Osteoporosis in men.
N Engl J Med, 358 (2008), pp. 1474-1482
[10.]
A.A. Abassi, D. Rudman, C.R. Wilson, et al.
Observations on nursing home patients with a history of hip fracture.
Am J Med Sci, 310 (1995), pp. 229-234
[11.]
S.P. Baillie, C.E. Davison, F.J. Johnson, R.M. Francis.
Pathogenesis of vertebral crush fractures in men.
Age Ageing, 21 (1992), pp. 139-141
[12.]
A.C. Looker, M.E. Mussolino.
Serum 25-hydroxyvitamin D and fracture risk in older U.S White adults.
J Bone Miner Res, 23 (2008), pp. 143-150
[13.]
C. Cooper.
Epidemiology of osteoporosis.
Osteoporos International, 9 (1999), pp. S2-S8
[14.]
S.L. Siverman, R.E. Madison.
Decreased incidence of hip fracture in Hispanics, Asians and Blacks: California hospital discharge data.
AM J Public Health, 78 (1988), pp. 1482-1483
[15.]
J.H. Tobias, D.G. Cook, T.J. Cjambers, et al.
A comparison of bone mineral density between Caucasian, Asian and Afro-Caribbean women.
Clin Sci, 87 (1994), pp. 587-591
[16.]
M.B. Mikhail, A.N. Vaswani, J.F. Aloia.
Racial differences in femoral dimensions and their relation to hip fracture.
Osteoporos Int, 6 (1996), pp. 22-24
[17.]
E. Dennison, M.A. Mohamed, C. Cooper.
Epidemiology of osteoporosis.
Rheum Dis Clin N Am, 32 (2006), pp. 617-629
[18.]
J.A. Kanis, O. Johnell, A. Oden, I. Sembo, I. Redlund- Johnell, A. Dawson, et al.
Long-term risk of osteoporotic fracture in Malmo.
Osteoporos Int, 11 (2000), pp. 669-674
[19.]
T.P. Van Staa, E.M. Dennison, H.G.M. Leufkens, et al.
Epidemiology of fractures in England and Wales.
Bone, 29 (2001), pp. 517-522
[20.]
O. Johnell, J.A. Kanis.
An estimate of the worldwide prevalence and disability associated with osteoporotic fractures.
Osteoporos Int, 17 (2006), pp. 1726-1733
[21.]
O. Johnell, J.A. Kanis.
An estimate of the worldwide prevalence, mortality and disability associated with hip fracture.
Osteoporos Int, 15 (2004), pp. 897-902
[22.]
C. Cooper, E.J. Atkinson, S.J. Jacobsen, et al.
Populationbased study of survival after osteoporotic fractures.
Am J Epidemiol, 137 (1993), pp. 1001-1005
[23.]
Hip fracture outcomes in people aged fifty and over: mortality, service use, expenditures, and long-term functional impairment. Washington, DC: Office of Technology Assessment, Congress of the United States; 1993. US Dept of Commerce Publication NTIS PB94107653.
[24.]
D.M. Kado, W.S. Browner, L. Palermo, et al.
Vertebral fractures and mortality in older women: a prospective study.
Arch Intern Med, 159 (1999), pp. 1215-1220
[25.]
E.A. Chrischilles, C.D. Butler, C.S. Davis, et al.
A model of lifetime osteoporosis impact.
Arch Intern Med, 151 (1991), pp. 2026-2032
[26.]
C. Baudoin, P. Fardellone, K. Bean, et al.
Clinical outcomes and mortality after hip fracture: a 2-year follow-up study.
Bone, 18 (1996), pp. 149S-157S
[27.]
D.T. Gold.
The clinical impact of vertebral fractures: quality of life in women with osteoporosis.
Bone, 18 (1996), pp. S185-S189
[28.]
T.W. O’Neill, W. Cockerill, C. Matthis, et al.
Back pain, disability, and radiographic vertebral fracture in European women: a prospective study.
Osteoporos Int, 15 (2004), pp. 760-765
[29.]
O. Johnell, J. Kanis.
Epidemiology of osteoporotic fractures.
Osteoporos Int, 16 (2005), pp. S3-S7
[30.]
D. Marshall, O. Johnell, H. Wedel.
meta-analysis of how well measures of bone mineral density predict occurence of osteoporotic fractures.
BMJ, 312 (1996), pp. 1254-1259
[31.]
J. Parkkari, P. Kannus, M. Palvanen, et al.
Majority of hip fractures occur as a result of a fall and impact on the greater trochanter of the femur: a prospective controlled hip fracture study with 206 consecutive patients.
Calcif Tissue Int, 65 (1999), pp. 183-187
[32.]
J.C. Gallagher, L.J. Melton, B.L. Riggs, et al.
Epidemiology of fractures of the proximal femur in Rochester Minnesota.
Clin Orthop Relat Res, 150 (1980), pp. 163-171
[33.]
C. Cooper, G. Campion, L.J. Melton III.
Hip fractures in the elderly: a world-wide projection.
Osteoporos Int, 2 (1992), pp. 285-289
[34.]
O. Johnell, B. Gullberg, J.A. Kanis, et al.
Risk factors for hip fracture in European Women: The MEDOS Study.
J Bone Miner Res, 10 (1995), pp. 1802-1814
[35.]
K. Chang, J. Center, Nguyen, et al.
Incidence of hip and other osteoporotic fractures in elderly men and women: Dubbo Osteoporosis Epidemiology Study.
J Bone Miner Res, 19 (2004), pp. 532-536
[36.]
J. Falch, H. Aho, K. Berglund, et al.
Hip fractures in Nordic cities: difference in incidence.
Ann Chir Gynaecol, 84 (1995), pp. 286-290
[37.]
H. Hagino, K. Yamamoto, R. Teshima, et al.
The incidence of fractures of the proximal femur and distal radius in Tottori Prefecture Japan.
Arch Orthop Trauma Surg, 109 (1990), pp. 43-44
[38.]
L. Solomon.
Osteoporosis and fracture of femoral neck in the South African Bantu.
J Bone Joint Surg Am, 50 (1968), pp. 2-13
[39.]
J. Morales Torres, S. Gutierrez-Urena.
The burden of osteoporosis in Latin America.
Osteoporos Int, 15 (2004), pp. 625-632
[40.]
N.F.A. Peel, N.A. Barrington, R. Eastell.
Prevalence of vertebral deformities in Sheffiel UK.
J Bone Miner Res, 7 (1992), pp. S327
[41.]
R. Eastell, S.L. Cedel, H.W. Wahner, B.L. Riggs, L.J. Melton 3rd..
Classification of vertebral fractures.
J Bone Miner Res, 6 (1991), pp. 207-215
[42.]
C. Cooper, E.J. Atkinson, W.M. O’Fallon, L.J. Melton III.
Incidence of clinically diagnosed vertebral fractures: a population based study in Rochester Minnesota, 1985-1989.
J Bone Miner Res, 7 (1992), pp. 221-227
[43.]
D. Kiel, Natural Osteoporosis Foundation Working Group on Vertebral Fractures..
Assessing vertebral fractures.
J Bone Miner Res, 10 (1995), pp. 518-523
[44.]
D.M. Black, M. Palermo, M.C. Nevitt, et al.
Comparison of methods for defining prevalent vertebral deformities: the Study of Osteoporotic Fractures.
J Bone Miner Res, 10 (1995), pp. 890-902
[45.]
D.M. Black, M. Palermo, M.C. Nevitt, et al.
Defining incident vertebral deformity: a prospective comparison of several approaches.
J Bone Miner Res, 14 (1999), pp. 90-101
[46.]
H.K. Genant, C. Wu, C. van Juijk, M. Nevitt.
Vertebral fracture assessment using a semi quantitative technique.
J Bone Miner Res, 8 (1993), pp. 1137-1148
[47.]
C. Cooper, L.J. Melton III.
Vertebral fracture: how large is the silent epidemic?.
BMJ, 304 (1992), pp. 793-794
[48.]
T.W. O’Neill, D. Felsenberg, J. Varlow, C. Cooper, J.A. Kanis, A.J. Silman.
The prevalence of vertebral deformity in european men and women: the European Vertebral Osteoporosis Study.
J Bone Miner Res, 11 (1996), pp. 1010-1018
[49.]
E.V. McCloskey, T.D. Spector, K.S. Eyres, E.D. Fern, N. O’Rourke, S. Vasikaran, J.A. Kanis.
The assessment of vertebral deformity: a method for use in population studies and clinical trials.
Osteoporos Int, 3 (1993), pp. 138-147
[50.]
A.A. Ismail, C. Cooper, D. Felsenberg, J. Varlow, J.A. Kanis, A.J. Silman, T.W. O’Neill, European Vertebral Osteoporosis Study Group..
Number and type of vertebral deformities: epidemiological characteristics and relation to back pain and height loss.
Osteoporos Int, 9 (1999), pp. 206-213
[51.]
The European Prospective Osteoporosis Study (EPOS) Group..
Incidence of vertebral fracture in Europe: Results from the European Prospective Osteoporosis Study (EPOS).
J Bone Miner Res, 17 (2002), pp. 716-724
[52.]
L.J. Melton III, A.W. Lane, C. Cooper, et al.
Prevalence and incidence of vertebral deformities.
Osteoporos Int, 3 (1993), pp. 113-119
[53.]
The European Prospective Osteoporosis Study (EPOS) Group..
The relationship between bone density and incident vertebral fracture in men and women.
J Bone Miner Res, 17 (2002), pp. 2214-2221
[54.]
F. Grados, C. Marcelli, P. Dargent-Molina, et al.
Prevalence of vertebral fractures in French women older than 75 years from the EPIDOS study.
[55.]
H.M. Frost.
Clinical management of the symptomatic osteoporotic patient.
Orthop Clin North Am, 12 (1981), pp. 671-681
[56.]
A.J. Silman, T.W. O’Neill, C. Cooper, et al.
Influence of physical activity on vertebral deformity in men and women: results from the European Vertebral Osteoporosis Study.
J Bone Miner Res, 12 (1997), pp. 813-819
[57.]
L.J. Melton III.
Epidemiology of fractures.
Osteoporosis: etiology, diagnosis and management, pp. 133-153
[58.]
P. Clark, F. Cons-Molina, M. Deleze, S. Ragi, L. Haddock, J.R. Zanchetta, J.J. Jaller, L. Palermo, J.O. Talavera, D.O. Messina, J. Morales-Torres, J. Salmeron, A. Navarrete, E. Suárez, C.M. Pérez, S.R. Cummings.
The prevalence of radiographic vertebral fractures in Latin American countries: the Latin American Vertebral Osteoporosis Study (LAVOS).
Osteoporos Int, 2 (2009), pp. 275-282
[59.]
X. Ling, S.R. Cummings, Q. Mingwei, Z. Xihe, C. Xioashu, M. Nevitt, K. Stone.
Vertebral fractures in Beijing China: the Beijing Osteoporosis Project.
J Bone Miner Res, 15 (2000), pp. 2019-2025
[60.]
Study of Osteoporotic Fractures (SOF): http://sof.ucsf.edu.
[61.]
P.D. Ross, J.W. Davis, R. Epstein, et al.
Pre-existing fractures and bone mass predict vertebral fracture incidence.
Ann Intern Med, 114 (1991), pp. 919-923
[62.]
C. Cooper.
Epidemiology of osteoporotic fracture: looking to the future.
Rheumatology, 44 (2005), pp. iv-iv40
[63.]
C. Cooper, M. Kotowicz, E.J. Atkinson, et al.
Risk of limb fractures among men and women with vertebral fractures.
Osteoporosis, pp. 101-104
[64.]
D.M. Black, N.K. Arden, L. Palermo, et al.
Prevalent vertebral deformities predict hip fractures and new vertebral deformities but not wrist fractures.
J Bone Miner Res, 14 (1999), pp. 821-828
[65.]
A.A. Ismail, W. Cockerill, C. Cooper, et al.
Prevalent vertebral deformity predicts incident hip fracture though not distal forearm fracture: results from the European Prospective Osteoporosis Study.
Osteoporosis International, 12 (2001), pp. 85-90
[66.]
K.E. Ensrud, J. Cauley, R. Lipschutz, et al.
Weight change and fractures in older women.
Arch Intern Med, 157 (1997), pp. 857-863
[67.]
D.G. Seeley, W.S. Browner, M.C. Nevitt, The Study of Osteoporotic Fractures Research Group., et al.
Which fractures are associated with low appendicular bone mass in elderly women?.
Ann Intern Med, 115 (1991), pp. 837-842
[68.]
J.L. Kelsey, W.S. Browner, D.G. Seeley, et al.
Risk factors for fractures of the distal forearm and proximal humerus.
Am J Epidemiol, 135 (1992), pp. 477-489
[69.]
World Health Organization. Assessment of fracture risk and its application to screening for postmenopausal osteoporosis. WHO technical report series. Geneva: WHO, 1994.
[70.]
D. Marshall, O. Johnell, H. Wedel.
Meta-analysis of how well measures of bone density predict occurrence of osteoporotic fractures.
BMJ, 312 (1996), pp. 1254-1259
[71.]
A.N. Tosteson, D.I. Rosenthal, L.J.I. Melton, M.C. Weinstein.
Cost-effectiveness of screening perimenopausal white women for osteoporosis: bone densitometry and hormone replacement therapy.
Ann Intern Med, 113 (1990), pp. 594-603
[72.]
ISCD.
Position Statement.
J Clin Densitom, 7 (2004), pp. 1-118
[73.]
M. Delezé Hinojoza, P. Clark, J. Morales Torres.
Osteoporosis: definición, clasificación y epidemiología.
Tratado Hispanoamericano de Reumatología, 1ra, pp. 1325-1338
[74.]
P. Garnero.
Markers of bone turnover for the prediction of fracture risk.
Osteoporos Int, 11 (1999), pp. S5-S65
[75.]
J.A. Cauley, L. Wu, N.S. Wampler, et al.
Clinical risk factors for fractures in multi-ethnic women: the Women's Health Initiative.
J Bone Miner Res, 22 (2007), pp. 1816-1826
[76.]
U. Sennerby, B. Farahmand, A. Ahlbom, et al.
Cardiovascular diseases and future risk of hip fracture in women.
Osteoporos Int, 18 (2007), pp. 1355-1362
[77.]
National Osteoporosis Fundation. Clinician's guide to prevention and treatment of osteoporosis. www.nof.org.
[78.]
Anonymous.
Guideline for the prevention of falls in older persons.
J Am Geriatr Soc, 49 (2001), pp. 664-672
[79.]
National Osteoporosis Foundation. Health Professional's Guide to Rehabilitation of Patients with Osteoporosis. 2003. Copyright NOF, Washington, DC.
[80.]
L.G. Raisz.
Screening for osteoporosis.
N Engl J Med, 353 (2005), pp. 164-171
[81.]
The World Health Organization Fracture Risk Assessment Tool. www.shef.ac.uk/FRAX.
[82.]
J.A. Kanis, O. Johnell, A. Oden, et al.
E. FRAX and the assessment of fracture probability in men and women in the UK.
Osteoporos Int, 19 (2008), pp. 385-397
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