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Inicio Revista Colombiana de Reumatología Tratamiento farmacológico de la osteoporosis postmenopáusica
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Vol. 17. Núm. 2.
Páginas 96-110 (junio 2010)
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Vol. 17. Núm. 2.
Páginas 96-110 (junio 2010)
Acceso a texto completo
Tratamiento farmacológico de la osteoporosis postmenopáusica
Pharmacological treatment of postmenopausal osteoporosis
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10633
Daniel G. Fernández Ávila1, Claudia Mora2, Elsa Reyes Sanmiguel2, John Darío Londoño2, Pedro Santos Moreno2, Rafael Valle-Oñate3
1 Médico Internista, Residente Reumatología, Universidad Militar Nueva Granada – Hospital Militar Central
2 Médico Internista, Reumatólogo, Hospital Militar Central. Profesor Universidad de La Sabana
3 Médico Internista, Reumatólogo, Jefe del Servicio de Reumatología, Hospital Militar Central. Profesor Universidad Militar Nueva Granada – Universidad de La Sabana
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Resumen

La osteoporosis es una enfermedad silenciosa hasta que se presenta su principal complicación: las fracturas; con un importante costo económico y social para el paciente y el sistema de salud, constituyéndose en un verdadero problema de salud pública. Las mujeres en la etapa postmenopáusica tienen un mayor riesgo de osteoporosis y por ende de fractura. Actualmente disponemos de un variado grupo de medicamentos que, a través de diferentes mecanismos de acción, mejoran la densidad mineral ósea y disminuyen el riesgo de fractura. En el presente artículo se presenta al lector información relevante de cada uno de los medicamentos empleados en el tratamiento de esta entidad desde el punto de vista farmacológico y de efectividad clínica.

Palabras clave:
osteoporosis
fractura
menopausia
densidad mineral ósea
Summary

Osteoporosis is a silent illness until fractures appears, with a very high economic and social cost for the patient and the health system, representing a true problem of public health. Postmenopausal women have a higher risk of osteoporosis and fracture. Actually are available different drugs that through a varied mechanism of action, increase bone mineral density and reduce fracture risk. In this article we present relevant information about the pharmacology and clinical effectiveness of each one of drugs used in the treatment of osteoporosis.

Key words:
osteoporosis
fracture
menopause
bone mineral density
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