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Inicio Revista Española de Anestesiología y Reanimación (English Edition) Use of cannabinoids for acute postoperative pain
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Vol. 71. Issue 8.
Pages 601-607 (October 2024)
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Vol. 71. Issue 8.
Pages 601-607 (October 2024)
Review
Use of cannabinoids for acute postoperative pain
Uso de cannabinoides en el dolor agudo postoperatorio
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C.A. Sanchis Verysera,
Corresponding author
sanchis_carver@gva.es

Corresponding author.
, J.M. Esparza Miñanab, J.V. Català Ripolla
a Facultativo Anestesiología, Reanimación y Tratamiento del Dolor, Hospital de Manises, Manises, Spain
b Responsable del Servicio de Anestesiología y Unidad del Dolor, Instituto Musculoesquelético Europeo, Valencia, Spain
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Table 1. Active ingredients in cannabis preparations.
Table 2. Clinical trials.
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Abstract

Doubts about the efficacy of medicinal cannabis in the treatment of acute postoperative pain are well justified, at least in light of the information gathered from Google Scholar, Clinical Trials, PubMed, and Cochrane databases.The conflation of cannabis and cannabinoids engenders not only normative but also medical implications. Despite cannabinoids having evinced their efficacy in the treatment of various pathologies, they have yet to demonstrate such in the context of acute postoperative pain.

The burgeoning corpus of research on this subject does instill a modicum of hope in this regard; nevertheless, the manifold methodological approaches employed obfuscate the prospect of reaching unequivocal conclusions.Given the current status of this matter, this article abstains from making a definitive pronouncement either in favor of or against the role of pharmaceuticals incorporating cannabinoid compounds in the management of acute postoperative pain.

Keywords:
Cannabinoid
Postoperative pain
Acute pain
Resumen

Las dudas acerca de la eficacia del cannabis medicinal en el tratamiento del dolor agudo postoperatorio están bien justificadas, al menos, a la vista de la información recogida en las bases de datos Google Scholar, Clinical Trials, PubMed y Cochrane. La confusión entre el cannabis y los cannabinoides genera efectos no sólo normativos sino también médicos. Pese a que los cannabinoides han demostrado su eficacia en el tratamiento de diversas patologías todavía no la han demostrado en el tratamiento del dolor agudo postoperatorio. El creciente número de estudios al respecto conlleva cierta esperanza en este sentido sin embargo la diversidad metodológica empleada lastra cualquier posibilidad de alcanzar hallazgos concluyentes. Dado el estado de la cuestión, este artículo no puede realizar una afirmación contundente a favor o en contra del papel de los fármacos con compuestos cannabinoides en el tratamiento del dolor agudo postoperatorio.

Palabras clave:
Cannabinoides
Dolor postoperatorio
Dolor agudo

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