Información del artículo
El Texto completo está disponible en PDF
References
[1.]
F.O. Walker.
Huntington's Disease.
Semin Neurol, 27 (2007), pp. 143-150
[2.]
Antonarakis SE, Chakravarti A, Cohen JC, Hardy J. Mendelian disorders and multifactorial traits: the big divide or one for all? Nat Rev Genet. May;11(5):380–4.
[3.]
Nothen MM, Nieratschker V, Cichon S, Rietschel M. New findings in the genetics of major psychoses. Dialogues Clin Neurosci.12(1):85–93.
[4.]
J.K. Millar, J.C. Wilson-Annan, S. Anderson, S. Christie, M.S. Taylor, C.A. Semple, et al.
Disruption of two novel genes by a translocation co-segregating with schizophrenia.
Hum Mol Genet, 9 (2000), pp. 1415-1423
[5.]
I. Chumakov, M. Blumenfeld, O. Guerassimenko, L. Cavarec, M. Palicio, H. Abderrahim, et al.
Genetic and physiological data implicating the new human gene G72 and the gene for D-amino acid oxidase in schizophrenia.
Proc Natl Acad Sci U S A, 99 (2002), pp. 13675-13680
[6.]
H. Stefansson, E. Sigurdsson, V. Steinthorsdottir, S. Bjornsdottir, T. Sigmundsson, S. Ghosh, et al.
Neuregulin 1 and susceptibility to schizophrenia.
Am J Hum Genet, 71 (2002), pp. 877-892
[7.]
R.E. Straub, Y. Jiang, C.J. MacLean, Y. Ma, B.T. Webb, M.V. Myakishev, et al.
Genetic variation in the 6p22.3 gene DTNBP1, the human ortholog of the mouse dysbindin gene, is associated with schizophrenia.
Am J Hum Genet, 71 (2002), pp. 337-348
[8.]
S. Mah, M.R. Nelson, L.E. Delisi, R.H. Reneland, N. Markward, M.R. James, et al.
Identification of the semaphorin receptor PLXNA2 as a candidate for susceptibility to schizophrenia.
Mol Psychiatry, 11 (2006), pp. 471-478
[9.]
T. Lencz, T.V. Morgan, M. Athanasiou, B. Dain, C.R. Reed, J.M. Kane, et al.
Converging evidence for a pseudoautosomal cytokine receptor gene locus in schizophrenia.
Mol Psychiatry, 12 (2007), pp. 572-580
[10.]
M.C. O’Donovan, N. Craddock, N. Norton, H. Williams, T. Peirce, V. Moskvina, et al.
Identification of loci associated with schizophrenia by genome-wide association and follow-up.
Nat Genet, 40 (2008), pp. 1053-1055
[11.]
S. Shifman, M. Johannesson, M. Bronstein, S.X. Chen, D.A. Collier, N.J. Craddock, et al.
Genome-wide association identifies a common variant in the reelin gene that increases the risk of schizophrenia only in women.
PLoS Genet, 4 (2008), pp. e28
[12.]
P.F. Sullivan, D. Lin, J.Y. Tzeng, E. van den Oord, D. Perkins, T.S. Stroup, et al.
Genomewide association for schizophrenia in the CATIE study: results of stage 1.
Mol Psychiatry, 13 (2008), pp. 570-584
[13.]
G. Kirov, I. Zaharieva, L. Georgieva, V. Moskvina, I. Nikolov, S. Cichon, et al.
A genome-wide association study in 574 schizophrenia trios using DNA pooling.
Mol Psychiatry, 14 (2009), pp. 796-803
[14.]
A.C. Need, D. Ge, M.E. Weale, J. Maia, S. Feng, E.L. Heinzen, et al.
A genome-wide investigation of SNPs and CNVs in schizophrenia.
PLoS Genet, 5 (2009), pp. e1000373
[15.]
Rare chromosomal deletions and duplications increase risk of schizophrenia.
Nature, 455 (2008), pp. 237-241
[16.]
J. Shi, D.F. Levinson, J. Duan, A.R. Sanders, Y. Zheng, I. Pe’er, et al.
Common variants on chromosome 6p22.1 are associated with schizophrenia.
Nature, 460 (2009), pp. 753-757
[17.]
H. Stefansson, R.A. Ophoff, S. Steinberg, O.A. Andreassen, S. Cichon, D. Rujescu, et al.
Common variants conferring risk of schizophrenia.
Nature, 460 (2009), pp. 744-747
[18.]
Nieratschker V, Nothen MM, Rietschel M. New Genetic Findings in Schizophrenia: Is there Still Room for the Dopamine Hypothesis of Schizophrenia? Front Behav Neurosci.4:23.
[19.]
D. Rujescu, A. Ingason, S. Cichon, O.P. Pietilainen, M.R. Barnes, T. Toulopoulou, et al.
Disruption of the neurexin 1 gene is associated with schizophrenia.
Hum Mol Genet, 18 (2009), pp. 988-996
[20.]
S.E. McCarthy, V. Makarov, G. Kirov, A.M. Addington, J. McClellan, S. Yoon, et al.
Microduplications of 16p11.2 are associated with schizophrenia.
Nat Genet, 41 (2009), pp. 1223-1227
[21.]
B. Xu, A. Woodroffe, L. Rodriguez-Murillo, J.L. Roos, E.J. van Rensburg, G.R. Abecasis, et al.
Elucidating the genetic architecture of familial schizophrenia using rare copy number variant and linkage scans.
Proc Natl Acad Sci U S A, 106 (2009), pp. 16746-16751
[22.]
B. Xu, J.L. Roos, S. Levy, E.J. van Rensburg, J.A. Gogos, M. Karayiorgou.
Strong association of de novo copy number mutations with sporadic schizophrenia.
Nat Genet, 40 (2008), pp. 880-885
[23.]
H. Stefansson, D. Rujescu, S. Cichon, O.P. Pietilainen, A. Ingason, S. Steinberg, et al.
Large recurrent microdeletions associated with schizophrenia.
Nature, 455 (2008), pp. 232-236
[24.]
G. Kirov, D. Gumus, W. Chen, N. Norton, L. Georgieva, M. Sari, et al.
Comparative genome hybridization suggests a role for NRXN1 and APBA2 in schizophrenia.
Hum Mol Genet, 17 (2008), pp. 458-465
[25.]
Karayiorgou M, Simon TJ, Gogos JA. 22q11.2 microdeletions: linking DNA structural variation to brain dysfunction and schizophrenia. Nat Rev Neurosci. Jun;11(6):402–16.
[26.]
T.A. Manolio, F.S. Collins, N.J. Cox, D.B. Goldstein, L.A. Hindorff, D.J. Hunter, et al.
Finding the missing heritability of complex diseases.
Nature, 461 (2009), pp. 747-753
[27.]
D.L. Braff, R. Freedman.
Clinically responsible genetic testing in neuropsychiatric patients: a bridge too far and too soon.
Am J Psychiatry, 165 (2008), pp. 952-955
[28.]
P. Borry, H. Howard.
DTC genetic services: a look across the pond.
Am J Bioeth, 8 (2008), pp. 14-16
[29.]
S.H. Katsanis, G. Javitt, K. Hudson.
Public health. A case study of personalized medicine.
Science, 320 (2008), pp. 53-54
[30.]
D.J. Hunter, M.J. Khoury, J.M. Drazen.
Letting the genome out of the bottle−will we get our wish?.
N Engl J Med, 358 (2008), pp. 105-107
[31.]
P. Kraft, D.J. Hunter.
Genetic risk prediction--are we there yet?.
N Engl J Med, 360 (2009), pp. 1701-1703
[32.]
Wilde A, Meiser B, Mitchell PB, Schofield PR. Public interest in predictive genetic testing, including direct-to-consumer testing, for susceptibility to major depression: preliminary findings. Eur J Hum Genet. Jan;18(1):47–51.
[33.]
M. Coors.
Genes in families: attitudes toward genetic testing for schizophrenia.
Schizophr Res, 72 (2005), pp. 271-273
[34.]
M.J. Hunter, C. Hippman, W.G. Honer, J.C. Austin.
Genetic counseling for schizophrenia: a review of referrals to a provincial medical genetics program from 1968 to.
Am J Med Genet A, 152A (2007), pp. 147-152
[35.]
G. Turner.
Presymptomatic screening for schizophrenia: a geneticist's perspective.
Aust N Z J Psychiatry, 34 (2000), pp. S204-S207
[36.]
V.L. Lyus.
The importance of genetic counseling for individuals with schizophrenia and their relatives: potential clients’ opinions and experiences.
Am J Med Genet B Neuropsychiatr Genet, 144B (2007), pp. 1014-1021
Copyright © 2010. SEP y SEPB