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Vol. 33. Issue 4.
Pages 443-446 (January 2009)
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Vol. 33. Issue 4.
Pages 443-446 (January 2009)
Cistitis eosinofílica: Revisión y reporte de dos casos
Eosinophilic cystitis: review and two cases report
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Luis F. Ebel Sepulveda
,1
Corresponding author
luisebel@uach.cl

Correspondencia autor: Dr. Luis F. Ebel Sepulveda Servicio de Urología. Hospital Regional de Valdivia Departamento de Urología. Universidad de Chile
, A. Foneron**, L. Troncoso*, R. Cañoles*, C. Carrasco**, A. Hornig*, G. Gil*, D. Corti*
* Servicio de Urología - Hospital Regional de Valdivia y Departamento de Urología - Universidad Austral de Chile
** Servicio de Anatomía Patológica - Hospital Regional de Valdivia. Universidad Austral de Chile Chile
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Resumen

La cistitis eosinofílica es una enfermedad de baja frecuencia, con menos de 200 casos reportados en el mundo. Se caracteriza por la inflamación de toda la pared vesical, predominantemente por eosinófilos, con fibrosis y áreas de necrosis muscular. Su origen parece ser inmunológico aunque los desencadenantes no se conocen bien. Se han descrito varios factores predisponentes como enfermedades alérgicas, trauma vesical, fármacos, infecciones, etc. Afecta a pacientes de todas las edades, preferentemente adultos. Se presenta con polaquiuria, hematuria y dolor suprapúbico. Otros de menor frecuencia son disuria, retención urinaria, nicturia y enuresis. El estudio de laboratorio (sedimento de orina, urocultivo, hemograma) y radiológico (ecotomografía, pielografía de eliminación, tomomografía computada y resonancia nuclear magnética) son inespecíficos. En la cistoscopía se observan lesiones que pueden simular otras enfermedades, por lo que el diagnóstico definitivo es histológico. El manejo puede ser expectante o con antihistamínicos, antiinflamatorios y corticoides. En los casos refractarios al tratamiento médico la cirugía puede ser una alternativa. Reportamos dos casos de pacientes hombres, adultos, con su cuadro de presentación, estudio y manejo.

Palabras clave:
Cistitis
Cistitis eosinofílica
Eosinofilia
Vejiga
Abstract

Eosinophilic cystitis is a low frequency disease, with less than 200 reported cases in the world. It is characterized by a bladder wall inflammation, mainly by eosinophils, with fibrosis and muscle necrosis areas. Its origin seems to be immunological, although the triggers are not well known. Several predispose factor have been described such as allergic diseases, bladder injuries, drugs, infections, etc. It affects patient of all ages, mainly adults. It presents with frecuency, haematuria and suprapubic pain. Other less frequent symptoms are disuria, urinary retention, nicturia, and enuresis. The laboratory study (urinalysis, urinalysis and haemogram) and radiology (ultrasound, intravenous pyelography, computed tomography and nuclear magnetic resonance) are non specific. The lesions observed in the cystoscopy could emulate other diseases, that why the proper diagnostic is the histological analysis. The management could be observation o antihistaminic, anti-inflammatory and corticoid treatment. In refractory cases, surgery is an alternative. In this work, two male adult cases are reported with their symptoms, studies and management.

Key words:
Cystitis
Eosinophilic cystitis
Eosinophilia
Bladder

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