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Inicio Actas Urológicas Españolas Relación entre niveles de testosterona en suero y cáncer prostático
Journal Information
Vol. 27. Issue 10.
Pages 788-792 (January 2003)
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Vol. 27. Issue 10.
Pages 788-792 (January 2003)
Relación entre niveles de testosterona en suero y cáncer prostático
Relation between levels of testosterone in serum and prostate cancer
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P. Rivera G.1, R. Tagle A., S. Mir C., R. González I.
Unidad de Urología. Facultad de Medicina. Universidad de La Frontera. Temuco. Chile
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Resumen
Introducción

La asociación entre testosterona y cáncer prostático es mal comprendida. Los niveles de testosterona no son concluyentes para distinguir procesos prostáticos benignos de malignos. El objetivo de nuestro trabajo es determinar la relación existente entre niveles de testosterona en suero y cáncer prostático.

Material y método

Se estudiaron en forma prospectiva 38 pacientes portadores de cáncer prostático y un grupo control de 32, con edades que fluctuaron entre los 50 y 80 años. La testosterona total y libre fue determinada por radioinmunoensayo. El análisis estadístico realizado fue descriptivo inferencial, con bandas de confianza de 95%.

Resultados

Los valores promedio de testosterona total y libre, fueron significativamente menores en los pacientes portadores de cáncer. No se demostró ninguna correlación entre gleason, antígeno prostático y etapa tumoral con testosterona sérica.

Conclusiones

Nuestro trabajo demostró que la testosterona es significativamente menor en los pacientes con cáncer prostático en relación a los controles.

Palabras clave:
Cáncer prostático
Testosterona
Abstract
Introduction

The association between testosterone and prostate cancer badly is understood. The testosterone levels are not conclusive to distinguish benign prostate processes of malignant. The objective of our work is to determine the relation between levels of serum testosterone and prostate cancer.

Material and method

38 patients with prostate cancer and a control group of 32 were studied in prospective form, with ages that fluctuated between the 50 and 80 years. The total and free testosterone was determined by radioinmunoensayo. The statistical analysis was descriptive inferential, with bands of 95% confidence.

Results

The average values of total and free testosterone, were significantly smaller in patients with prostate cancer. Any correlation between gleason, prostate antigen and stage with testosterone, was not demonstrated.

Conclusions

Our work demonstrated that the testosterone is significantly smaller in the patients with prostate cancer that in the controls.

Key words:
Prostate cancer
Testosterone

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