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Inicio Archivos de la Sociedad Española de Oftalmología (English Edition) Atypical presentation of type 1 neovascularization with aneurysmal dilations in ...
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Vol. 99. Issue 12.
Pages 562-565 (December 2024)
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Vol. 99. Issue 12.
Pages 562-565 (December 2024)
Short communication
Atypical presentation of type 1 neovascularization with aneurysmal dilations in a young female
Presentación atípica de neovascularización tipo 1 con dilataciones aneurismáticas en una mujer joven
M. Zamoranoa,
Corresponding author
margazamo@gmail.com

Corresponding author.
, B. Puertob, J. Carcellerb, J.J. González-Lópezb, M.S. Figueroab, F.J. Muñoz-Negreteb
a Department of Ophthalmology, University Hospital Guadalajara, Guadalajara, Spain
b Department of Ophthalmology, Ramon y Cajal University Hospital, Madrid, Spain
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Abstract

Type 1 Neovascularization with Aneurysmal Dilations (N1a), is a retinal disorder characterized by choroidal vascular abnormalities. Clinically, it is characterized by an exudative maculopathy with multiple recurrent serosanguineous pigment epithelial detachments. This disease is more frequent in women aged 55–65 years. However, we present an exceptional case of N1a in a 26-year-old woman, who responded favorably to Aflibercept. To our knowledge, this is the first reported case of a young female patient under 30 with N1a. The patient has responded very favourably to anti-VEGF therapy with three intravitreal injections of Aflibercept. This being the reason for we provide an update on anti-VEGF therapeutic options for N1a.

Keywords:
Retina
Polypoidal choroidal vasculopathy
Choroidal vascular abnormalities
Recurrent serosanguineous pigment epithelial detachments
Resumen

La neovascularización tipo 1 con dilataciones aneurismáticas (N1a) es un trastorno de la retina caracterizado por anomalías vasculares coroideas. Clínicamente, se caracteriza por una maculopatía exudativa con múltiples desprendimientos serosanguinolientos del epitelio pigmentario recurrentes. Esta enfermedad es más frecuente en mujeres de 55 a 65 años. Sin embargo, presentamos un caso excepcional de N1a en una mujer de 26 años, que respondió favorablemente a Aflibercept. Hasta donde sabemos, este es el primer caso reportado de una mujer joven menor de 30 años con N1a. Además, proporcionamos una breve revisión de las opciones terapéuticas anti-VEGF para la N1a.

Palabras clave:
Retina
Neovascularización tipo 1 con dilataciones aneurismáticas
Anomalías vasculares coroideas
Desprendimiento serosanguinoliento recurrente del EPR

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