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"apellidos" => "Alderete-Vázquez" ] ] ] ] ] "idiomaDefecto" => "en" "Traduccion" => array:1 [ "es" => array:9 [ "pii" => "S0365669112002080" "doi" => "10.1016/j.oftal.2012.04.017" "estado" => "S300" "subdocumento" => "" "abierto" => array:3 [ "ES" => false "ES2" => false "LATM" => false ] "gratuito" => false "lecturas" => array:1 [ "total" => 0 ] "idiomaDefecto" => "es" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0365669112002080?idApp=UINPBA00004N" ] ] "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S2173579413000637?idApp=UINPBA00004N" "url" => "/21735794/0000008800000004/v1_201306181844/S2173579413000637/v1_201306181844/en/main.assets" ] "en" => array:20 [ "idiomaDefecto" => true "cabecera" => "Short communication" "titulo" => "Orbital giant conjunctival epithelial primary cyst" "tieneTextoCompleto" => true "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "157" "paginaFinal" => "159" ] ] "autores" => array:1 [ 0 => array:4 [ "autoresLista" => "F.J. Guijarro-Oria, E. Mencía-Gutiérrez, E. Gutiérrez-Díaz, E. López-Tizón" "autores" => array:4 [ 0 => array:2 [ "nombre" => "F.J." "apellidos" => "Guijarro-Oria" ] 1 => array:4 [ "nombre" => "E." "apellidos" => "Mencía-Gutiérrez" "email" => array:2 [ 0 => "emencia.hdoc@salud.madrid.org" 1 => "emenciag@gmail.com" ] "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "¿" "identificador" => "cor0005" ] ] ] 2 => array:2 [ "nombre" => "E." "apellidos" => "Gutiérrez-Díaz" ] 3 => array:2 [ "nombre" => "E." "apellidos" => "López-Tizón" ] ] "afiliaciones" => array:1 [ 0 => array:1 [ "entidad" => "Servicio de Oftalmología, Hospital 12 de Octubre, Universidad Complutense, Madrid, Spain" ] ] "correspondencia" => array:1 [ 0 => array:3 [ "identificador" => "cor0005" "etiqueta" => "⁎" "correspondencia" => "Corresponding author." ] ] ] ] "titulosAlternativos" => array:1 [ "es" => array:1 [ "titulo" => "Quiste conjuntival epitelial gigante primario orbitario" ] ] "resumenGrafico" => array:2 [ "original" => 0 "multimedia" => array:7 [ "identificador" => "fig0015" "etiqueta" => "Fig. 3" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr3.jpeg" "Alto" => 1230 "Ancho" => 1667 "Tamanyo" => 351164 ] ] "descripcion" => array:1 [ "en" => "Supero-anterior orbitotomy for extraction of the cystic lesion." ] ] ] "textoCompleto" => "IntroductionCystic lesions account for 8% of adult orbitary tumors. Dermoid cysts are most frequent while conjunctival cysts are comparatively exceptional in the orbit.<a class="elsevierStyleCrossRef" href="#bib0005">1</a> These can be primary or more frequently secondary (67%) to the implementation of conjunctival tissue in the orbit, either due to trauma or iatrogeny,<a class="elsevierStyleCrossRef" href="#bib0010">2</a> derived from surgery due to strabismus, enucleation or retinal surgery.Only 27 cases of primary orbitary conjunctival cysts have been previously described.<a class="elsevierStyleCrossRef" href="#bib0015">3</a>Case reportMale, 15, without ocular traumatic or surgical history, exhibiting proptosis with inferior displacement of the right ocular globe and slight inflammatory reaction beginning 4 months back.Exploration revealed a superior orbit tumor protruding at the level of the sac fundus having a cystic translucent appearance with serous contents, without vascularization and a size of 3.5cm×2.5cm (<a class="elsevierStyleCrossRef" href="#fig0005">Fig. 1</a>), as well as internal conjunctival symblepharon. Echography revealed a round and capsulated cystic mass located between the upper eyelid elevator and upper rectus muscles, reaching the equatorial level from the upper orbitary edge (<a class="elsevierStyleCrossRef" href="#fig0010">Fig. 2</a>A). An orbitary CAT scan revealed a cystic lesion with a thin and well-defined line and hypo-intense content (<a class="elsevierStyleCrossRef" href="#fig0010">Fig. 2</a>B), which discarded a dermoid cyst, lymphangioma or vascular tumor and indicated possible retention cyst. The possibility of a hydatid cyst was discarded upon reception of the normal results of serology, latex, and abdominal and thoracic echographies.<elsevierMultimedia ident="fig0005"></elsevierMultimedia><elsevierMultimedia ident="fig0010"></elsevierMultimedia>Trans-conjunctival antero-superior orbitomy was performed removing the cyst in toto, which exhibited a thin wall and was translucent and comprising serous liquid content (<a class="elsevierStyleCrossRef" href="#fig0015">Fig. 3</a>).<elsevierMultimedia ident="fig0015"></elsevierMultimedia>The anatomopathological study revealed a non-keratinized epithelial wall with mucin-excreting cup-shaped cells without the presence of dermic elements, which allowed for a diagnosis of primary and idiopathic simple conjunctival inclusion cyst (<a class="elsevierStyleCrossRef" href="#fig0020">fig. 4</a>).<elsevierMultimedia ident="fig0020"></elsevierMultimedia>After 10 years follow-up the patient did not exhibit relapse or developed a new lesion.DiscussionThe pathogenesis of orbitary conjunctival cysts is unknown. A postulated cause is excessive invagination of the caruncular epithelium or the fornix<a class="elsevierStyleCrossRef" href="#bib0020">4</a> during embryonic development<a class="elsevierStyleCrossRef" href="#bib0015">3</a> similar to the pathogenesis of dermoid and epidermoid cysts. Other authors have considered the possibility of the sequestering of ectodermic pluripotential superficial cells with the ability to differentiate in one or more epithelial types.<a class="elsevierStyleCrossRef" href="#bib0005">1</a>At the histopathological level, dermoid cysts comprise keratinized stratified squamous epithelium with cutaneous appendices,<a class="elsevierStyleCrossRef" href="#bib0005">1</a> while in conjunctival cysts the epithelium is squamous but not keratinized, generally without cutaneous appendices<a class="elsevierStyleCrossRefs" href="#bib0010">2,3</a> although in some cases said appendices can be present in the walls, or mucin-secreting cup-shaped cells.<a class="elsevierStyleCrossRefs" href="#bib0005">1,4,5</a>The age of presentation of said cysts varies from birth up to 70 years of age<a class="elsevierStyleCrossRefs" href="#bib0005">1,2,4</a> and in patients over 40 it appears in only 25% of cases. Previous evolution time can range between several months up to 60 years,<a class="elsevierStyleCrossRefs" href="#bib0005">1,4</a> and the typical clinic consists in a painless cystic mass of small-moderate size<a class="elsevierStyleCrossRefs" href="#bib0005">1,3,4</a> which can associate proptosis and ocular globe displacement although generally extrinsic muscle motility is respected<a class="elsevierStyleCrossRef" href="#bib0020">4</a> as well as the bone structure.<a class="elsevierStyleCrossRefs" href="#bib0005">1,2,4</a>The most common location is in the supero-nasal region, followed by the supero-temporal region<a class="elsevierStyleCrossRefs" href="#bib0005">1,4</a> where bone involvement cases have been described.<a class="elsevierStyleCrossRef" href="#bib0005">1</a>As primary conjunctival cysts are typified as non-keratinized epithelium, histopathological diagnostic mistakes with mucoceles can occur<a class="elsevierStyleCrossRef" href="#bib0005">1</a> which includes bone involvement with communication to paranasal sinuses.With rare exceptions, orbitary conjunctival cysts are masses of thin walls and low pressure which generally do not induce significant mechanical alterations.<a class="elsevierStyleCrossRef" href="#bib0010">2</a> However, there are cases in which a recurring conjunctival cyst has eroded the bone structure and produced visual symptoms as well as spontaneous hemorrhage which increases orbitary pressure and associates inflammation and pain.<a class="elsevierStyleCrossRefs" href="#bib0005">1,4</a> This demonstrates its potential capacity to produce anatomic and functional alterations.<a class="elsevierStyleCrossRef" href="#bib0010">2</a>The differential diagnostic of orbitary cystic lesions is established between lesions that characteristically have a hyper-dense capsule image in its central content, in contrast with other orbitary tumors. The diagnostic is established between epidermoid cysts, mucoceles, hydatic, hematic, cholesteatoma and conjunctival (or inclusion cysts). Data such as age, location, history of trauma or surgery or sinusitis are useful for correct diagnostic, with imaging tests being essential for circumscribing and treating the lesion.Small asymptomatic tumors can be managed with a conservative approach by means of follow-up, whereas large and symptomatic tumors require surgery and generally exhibit good post-surgery evolution without recurrences.<a class="elsevierStyleCrossRef" href="#bib0020">4</a>Conflict of interestsNo conflict of interest has been declared by the authors." "textoCompletoSecciones" => array:1 [ "secciones" => array:9 [ 0 => array:2 [ "identificador" => "xres190813" "titulo" => array:3 [ 0 => "Abstract" 1 => "Case report" 2 => "Discussion" ] ] 1 => array:2 [ "identificador" => "xpalclavsec178275" "titulo" => "Keywords" ] 2 => array:2 [ "identificador" => "xres190812" "titulo" => array:3 [ 0 => "Resumen" 1 => "Caso clínico" 2 => "Discusión" ] ] 3 => array:2 [ "identificador" => "xpalclavsec178276" "titulo" => "Palabras clave" ] 4 => array:2 [ "identificador" => "sec0005" "titulo" => "Introduction" ] 5 => array:2 [ "identificador" => "sec0010" "titulo" => "Case report" ] 6 => array:2 [ "identificador" => "sec0015" "titulo" => "Discussion" ] 7 => array:2 [ "identificador" => "sec0020" "titulo" => "Conflict of interests" ] 8 => array:1 [ "titulo" => "References" ] ] ] "pdfFichero" => "main.pdf" "tienePdf" => true "fechaRecibido" => "2011-10-05" "fechaAceptado" => "2012-04-08" "PalabrasClave" => array:2 [ "en" => array:1 [ 0 => array:4 [ "clase" => "keyword" "titulo" => "Keywords" "identificador" => "xpalclavsec178275" "palabras" => array:5 [ 0 => "Cyst" 1 => "Conjunctival epithelial" 2 => "Primary" 3 => "Giant" 4 => "Orbit" ] ] ] "es" => array:1 [ 0 => array:4 [ "clase" => "keyword" "titulo" => "Palabras clave" "identificador" => "xpalclavsec178276" "palabras" => array:5 [ 0 => "Quiste" 1 => "Epitelio conjuntival" 2 => "Primario" 3 => "Órbita" 4 => "Gigante" ] ] ] ] "tieneResumen" => true "resumen" => array:2 [ "en" => array:2 [ "titulo" => "Abstract" "resumen" => "Case reportA 15-year-old male, with no previous traumatic o surgical ocular injury, presented with a right eye proptosis and inferior displacement which began 4 months earlier. Ultrasound and CT showed a cystic lesion of 3.5cm×2cm in the superior orbit. Surgical resection was performed by transconjunctival orbitotomy. The histopathology examination showed a cyst with nonkeratinized epithelium, and without goblet cells. After 10 years of follow-up, there have been no new lesions. DiscussionConjunctival primary orbital cysts are very uncommon. They are usually of small-moderate size; giant cysts are exceptional. Diagnosis by imaging is essential to establish the differential diagnosis and surgical treatment." ] "es" => array:2 [ "titulo" => "Resumen" "resumen" => "Caso clínicoVarón de 15 años de edad, sin antecedente traumático o quirúrgico, que presenta proptosis con desplazamiento inferior del globo ocular derecho de cuatro meses de evolución. La ecografia y la TAC muestran una lesión quística de 3,5 × 2cm. Se reseca mediante orbitotomía transconjuntival. La histopatología muestra un quiste con un epitelio no queratinizado sin células caliciformes. Después de 10 años de evolución no ha recidivado. DiscusiónLos quistes epiteliales conjuntivales primarios son muy infrecuentes. Suelen ser de pequeño-moderado tamaño; los gigantes son excepcionales. El diagnóstico por imagen es fundamental para el diagnóstico diferencial y el tratamiento quirúrgico." ] ] "NotaPie" => array:1 [ 0 => array:2 [ "etiqueta" => "☆" "nota" => "Please cite this article as: Guijarro-Oria FJ, et al. Quiste conjuntival epitelial gigante primario orbitario. Arch Soc Esp Oftalmol. 2013;88:157–9." ] ] "multimedia" => array:4 [ 0 => array:7 [ "identificador" => "fig0005" "etiqueta" => "Fig. 1" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr1.jpeg" "Alto" => 1077 "Ancho" => 1375 "Tamanyo" => 308539 ] ] "descripcion" => array:1 [ "en" => "Cyst protruding through the upper right palpebral sac, with translucent wall and serous content." ] ] 1 => array:7 [ "identificador" => "fig0010" "etiqueta" => "Fig. 2" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr2.jpeg" "Alto" => 864 "Ancho" => 2333 "Tamanyo" => 258395 ] ] "descripcion" => array:1 [ "en" => "(A) Echography and (B) orbitary computerized axial tomography demonstrating the existence of a cyst in the right upper orbit with hypotense content, thin wall and large volume." ] ] 2 => array:7 [ "identificador" => "fig0015" "etiqueta" => "Fig. 3" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr3.jpeg" "Alto" => 1230 "Ancho" => 1667 "Tamanyo" => 351164 ] ] "descripcion" => array:1 [ "en" => "Supero-anterior orbitotomy for extraction of the cystic lesion." ] ] 3 => array:7 [ "identificador" => "fig0020" "etiqueta" => "Fig. 4" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr4.jpeg" "Alto" => 1075 "Ancho" => 1667 "Tamanyo" => 343409 ] ] "descripcion" => array:1 [ "en" => "The cyst histopathology reveals a thin wall made up of several layers of cuboid epithelium without mucin-secreting cells. 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"serieFecha" => "2008" ] ] ] ] ] ] ] ] ] ] ] "idiomaDefecto" => "en" "url" => "/21735794/0000008800000004/v1_201306181844/S2173579413000649/v1_201306181844/en/main.assets" "Apartado" => array:4 [ "identificador" => "5812" "tipo" => "SECCION" "en" => array:2 [ "titulo" => "Short communications" "idiomaDefecto" => true ] "idiomaDefecto" => "en" ] "PDF" => "https://static.elsevier.es/multimedia/21735794/0000008800000004/v1_201306181844/S2173579413000649/v1_201306181844/en/main.pdf?idApp=UINPBA00004N&text.app=https://www.elsevier.es/" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S2173579413000649?idApp=UINPBA00004N"]

ISSN: 2173-5794
e-ISSN: 1989-7286

Archivos de la Sociedad Española de Oftalmología is the official journal of the Ophthalmology Society of Spain, that has over 4,000 members. It gives priority to the publication of basic, translational and clinic research including reviews, original articles, short communications, editorials, letters to the editor and clinic practice guides related to Ophthalmology and its subspecialties. A small section of the journal is reserved for the most relevant papers presented at the annual Congress of the Society. All manuscripts considered for publication are reviewed by expert examiner peers (double blind). The journal is published monthly and even though its official language is Spanish all articles are translated into English to increase the dissemination of scientific information. At present, Archivos is the only Spanish language Ophthalmology journal indexed in PubMed/MEDLINE in addition to other prestigious international databases such as Scopus.

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