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Vol. 25. Issue 9.
Pages 613-617 (January 2000)
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Vol. 25. Issue 9.
Pages 613-617 (January 2000)
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Factores relacionados con la distensibilidad arterial en la hipertensión
Factors relating to arterial compliance in hypertension
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M.J. Fernández-Marcos, A. Menéndez-Pertierra, J.E. Cimas
Corresponding author
jcimash@meditex.es

Correspondencia: Juan Enrique Cimas Hernando. Avda. Rufo García Rendueles, 22, 6.° F. 33203 Gijón (Asturias).
, E. Carril
Centro de Salud de Cabañaquinta–Aller (Asturias)
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Objetivo

Averiguar qué variables influyen en las alteraciones de la distensibilidad arterial en los sujetos hipertensos mediante medición de la velocidad de onda de pulso (VOP).

Diseño

Estudio descriptivo transversal.

Ámbito

Centro de salud rural.

Sujetos

Ciento cincuenta y seis pacientes hipertensos menores de 76 años, seleccionados por medio de muestreo aleatorio simple entre los incluidos en el registro de hipertensión arterial (HTA).

Mediciones e intervenciones

Determinamos grado de HTA, años de evolución, tensión arterial sistólica (TAS) y diastólica (TAD), índice de masa corporal (IMC), glucemia, existencia de dislipemia, diabetes o intolerancia a la glucosa, hábito tabáquico, edad, sexo y VOP (medición automática por ordenador). Realizamos análisis multivariante mediante regresión lineal múltiple, siendo la variable dependiente la VOP y las independientes edad, TAS, TAD, IMC, años de evolución de la HTA, colesterol, triglicéridos y glucemia.

Resultados

Edad media 62,5 (DE, 8,8); el 28,2% varones; TAS media, 153 (DE, 18,9); TAD media, 87 (DE, 10,3); media de años de evolución, 10,4 (DE, 7,4); IMC medio, 31,2 (DE, 4,9); hiperglucemia, 24,4%; glucemia media, 111,3 (DE, 29); VOP media, 11,82 (DE, 2,37). La VOP era superior a las cifras normales teóricas en un 69,2%. La regresión lineal múltiple mostró que las variables que influyen significativamente en la VOP son edad, TAS e hiperglucemia.

Conclusiones

La mejora de la distensibilidad arterial puede obtenerse controlando la TAS, puesto que los otros factores relacionados son inmodificables.

Palabras clave:
Distensibilidad arterial
Hipertensión arterial
Velocidad onda pulso
Objective

To find out what variables affect changes in arterial compliance in subjects with hypertension by measuring their pulse wave velocity (PWV).

Design

Cross-sectional, descriptive study.

Setting

Rural health centre.

Patients

156 hypertense patients under 76, chosen by simple random sampling from those on the hypertension register.

Measurements and interventions

We determined the degree of hypertension, years of evolution, systolic pressure (SBP), diastolic pressure (DBP), body mass index (BMI), glucaemia, whether lipaemia existed, diabetes or glucose intolerance, tobacco habit, age, sex and PWV (measured automatically by computer).We performed multivariate analysis by means of multiple linear regression, with PWV as the dependent variable, and age, SBP, DBP, BMI, years of evolution of hypertension, cholesterol, triglycerides and glucaemia as independent variables.

Results

Mean age 62.5 (SD 8.8). 28.2% male. Mean SBP 153 (SD 18.9). Mean DBP 87 (SD 10.3). Mean years of evolution 10.4 (SD 7.4). Mean BMI 31.2 (SD 4.9). Hyperglucaemia 24.4%. Mean glucaemia 111.3 (SD 29). Mean PWV 11.82 (SD 2.37). PWV was above the theoretically normal figures in 69.2% of cases. Multiple linear regression showed that the variables which affected PWV significantly were age, SBP and hyperglucaemia.

Conclusions

Arterial compliance can be improved by controlling SBP, given that the other related factors cannot be changed.

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Bibliografía
[1.]
M.E. Safar.
Hemodynamic changes in elderly hypertensive patients.
Am J Hypertens, 6 (1993), pp. 20-23
[2.]
M.E. Safar, S. Laurent.
Behaviour of conduit arteries in hypertension.
Clin Exper Hypertension, 15 (1993), pp. 1033-1045
[3.]
R.S. Reneman, A.P.G. Hocks.
Arterial distensibility and compliance in hypertension.
Neth J Med, 47 (1995), pp. 152-161
[4.]
A. Benetos, S. Laurent, A.P. Hoeks, P.H. Boutouyrie, M.E. Safar.
Arterial alterations with aging and high blood pressure. A non-invasive study of carotid and femoral arteries.
Arterios Thrombos, 13 (1993), pp. 90-97
[5.]
R. Asmar, A. Benetos, J. Topouchian, P. Laurent, B. Pannier, A.M. Brisac, et al.
Assesment of arterial distensibility by automatic pulse wave velocity measurement. Validation and clinical application studies.
Hypertension, 26 (1995), pp. 485-490
[6.]
J. Maldonado, M. Pego, M. Bastos, H. Guimaraes, V. Monteiro, L.A. Providencia.
A velocidade da onda de pulso como expressao da compliance arterial e sua importancia na avaliacao da hipertensao arterial.
Rev Port Cardiol, 11 (1992), pp. 929-932
[7.]
C.T. Ting, C.H. Chen, M.S. Chang, F.C.P. Yin.
Short -and long -term effects of antihypertensive drugs on arterial reflections, compliance and impedance.
Hypertension, 26 (1995), pp. 524-530
[8.]
R. De Cesaris, G. Ranieri, V. Filitti, A. Andriani, M.V. Bonfantino.
Forearm arterial distensibility in patients with hypertension: comparative effects of longterm ACE inhibition and β-blocking.
Clin Pharmacol Ther, 53 (1992), pp. 360-367
[9.]
G.E. McVeigh, S.M. Finkelstein, J.N. Cohn.
Assesment of arterial compliance in hypertension.
Curr Op Neph Hypertension, 2 (1993), pp. 82-86
[10.]
D. Fores, J. Soler, L. Marcos.
Hiperlipemias.
Atencion primaria. Conceptos, organizacion y practica clinica, 3.a, pp. 510-529
[11.]
A. Taquet, C. Bonithon-Kopp, A. Simon, J. Levenson, Y. Scarabin, A. Malmejac, et al.
Relations of cardiovascular risk factors to aortic pulse wave velocity in asymptomatic middle-aged women.
Eur J Epidemiology, 9 (1993), pp. 298-306
[12.]
A.P. Avolio, S.C. Cheng, R.P. Wang, C.L. Zhang, M.F. Li, M.F. O'Rourke.
Effects of aging on changing arterial compliance and left ventricular load in a Northern Chinese urban community.
Circulation, 68 (1983), pp. 50-58
[13.]
J. Levenson, N. Del Pino, M. Razavian, Y. Merli, V. Filitti, A. Simon.
Hypercholesterolemia alters arterial and blood factors related to atherosclerosis in hypertension.
Atherosclerosis, 95 (1992), pp. 171-179
[14.]
R. Cunha, A. Benetos, S. Laurent, M.E. Safar, R. Asmar.
Distension capacity of the carotid artery and ambulatory blood pressure monitoring. Effects of age and hypertension.
Am J Hypertension, 8 (1995), pp. 343-352
[15.]
S. Madhavan, W. Lock Ooi, H. Cohen, M. Alderman.
Relation of pulse pressure reduction to the incidence of myocardial infarction.
Hypertension, 23 (1994), pp. 395-401
[16.]
J.L. Megnien, A. Simon, P. Valensi, P. Flaud, Y. Merli, J. Levenson.
Comparative effects of diabetes mellitus and hypertension on physical properties of human large arteries.
J Am Coll Cardiol, 20 (1992), pp. 1562-1568
[17.]
P. Darlu, P.P. Sagnier, E. Bois.
Evidences for genetical transmission of the pulse arterial pressure.
C R Acad Sci III, 317 (1994), pp. 62-69
[18.]
M.E. Safar, E.D. Frohlich.
The arterial system in hypertension. A prospective view.
Hypertension, 26 (1995), pp. 10-14
[19.]
R. De Cesaris, G. Ranieri, V. Filitti, A. Andriani.
Large artery compliance in essential hypertension. Effects of calcium antagonism and a-blocking.
Am J Hypertension, 5 (1992), pp. 624-628
[20.]
L. Van Bortel, M. Kool, J. Spek.
Disparate effects of antihypertensive drugs on large artery distensibility and compliance in hypertension.
Am J Cardiol, 76 (1995), pp. 46-49
[21.]
N. Chau, A. Simon, J. Vilar, E. Cabrera-Fisher, I. Pithois-Merli, J. Levenson.
Active and passive effects of antihypertensive drugs on essential hypertension.
J Cardiovasc Pharmacol, 19 (1992), pp. 78-85
[22.]
A. Dart, C. Silagy, E. Dewar, G. Jennings, J. McNeil.
Aortic distensibility and left ventricular structure and function in isolated systolic hypertension.
Eur Heart J, 14 (1993), pp. 1465-1470
Copyright © 2000. Elsevier España, S.L.. Todos los derechos reservados
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