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COMMENTS
Comments on “Evaluation of the Accuracy of Mammography, Ultrasound and Magnetic Resonance Imaging in Suspect Breast Lesions”
Yongyu An
Corresponding author
an1518068842@163.com

Corresponding author.
Department of Radiology, Tongde Hospital of Zhejiang Province, Zhejiang Province, China
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    "textoCompleto" => "<span class="elsevierStyleSections"><p id="para10" class="elsevierStylePara elsevierViewall">Dear Editor&#58;</p><p id="para20" class="elsevierStylePara elsevierViewall">I read the article &#40;<a class="elsevierStyleCrossRef" href="#bib1">1</a>&#41; &#8220;Evaluation of the accuracy of mammography&#44; ultrasound and magnetic resonance imaging in suspect breast lesions&#8221; &#40;Pereira et al&#46;&#41; with great interest&#59; however&#44; I am left confused by the study and believe some issues must be discussed&#46;</p><p id="para30" class="elsevierStylePara elsevierViewall">The aim of this study was to compare the diagnostic performance of three imaging methods for breast cancer &#40;<a class="elsevierStyleCrossRef" href="#bib1">1</a>&#41;&#46; However&#44; all patients showed a suspect breast lesion on evaluation by at least one of the methods&#46; Based on the Breast Imaging-Reporting and Data System &#40;BI-RADS&#41;&#44; biopsy or surgical resection was recommended&#59; however&#44; the positive predictive value for BI-RADS categories 4 and 5 varies depending on the imaging modality&#46; For instance&#44; almost 90&#37; of the suspect lesions detected by ultrasound eventually show negative results&#44; leading to unnecessary biopsies &#40;<a class="elsevierStyleCrossRef" href="#bib2">2</a>&#41;&#46; In this setting&#44; the role of other imaging modalities is to evaluate whether a suspected lesion is truly malignant&#46; Hence&#44; magnetic resonance imaging &#40;MRI&#41; is the superior modality as it shows high sensitivity for breast cancer detection and has a high negative predictive value for the exclusion of malignancy &#40;<a class="elsevierStyleCrossRefs" href="#bib3">3&#8211;5</a>&#41;&#44; as shown in the study by Pereira at al&#46; &#40;<a class="elsevierStyleCrossRef" href="#bib1">1</a>&#41;&#46; Furthermore&#44; several studies have suggested that MRI could be used as a problem-solving tool in cases of suspicious clinical and radiological findings &#40;<a class="elsevierStyleCrossRefs" href="#bib6">6&#8211;8</a>&#41;&#46;</p><p id="para40" class="elsevierStylePara elsevierViewall">Finally&#44; I do not agree with the statement that MRI has low specificity owing to high breast density&#46; Breast density has a vital impact on the interpretation of mammography findings&#44; but not on that of MRI findings&#46; On dynamic contrast-enhanced MRI&#44; both morphology and kinetics are key for the diagnosis of breast lesions&#44; although there is considerable overlap between signs of benign and malignant lesions&#44; resulting in false-positive findings&#46; Several studies have revealed that diffusion-weighted imaging can improve the specificity of breast MRI and help avoid unnecessary biopsies &#40;<a class="elsevierStyleCrossRef" href="#bib9">9</a>&#44;<a class="elsevierStyleCrossRef" href="#bib10">10</a>&#41;&#46; The specificity shown in this study was low &#40;<a class="elsevierStyleCrossRef" href="#bib1">1</a>&#41;&#59; hence&#44; I wonder whether diffusion-weighted imaging was integrated into breast MRI&#46; I would be interested in receiving responses to my comments&#46;</p></span>"
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Article information
ISSN: 18075932
Original language: English
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