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CLINICAL SCIENCE
High-fidelity simulation versus case-based discussion for teaching medical students in Brazil about pediatric emergencies
Thomaz Bittencourt CoutoI,
Corresponding author
thomaz.couto@hc.fm.usp.br

Thomaz Bittencourt Couto Corresponding author:
, Sylvia C.L. FarhatI, Gary L GeisII, Orjan OlsenIII, Claudio SchvartsmanI
I Faculdade de Medicina da Universidade de São Paulo, Department of Pediatrics, São Paulo/SP, Brazil
II Cincinnati Children's Hospital Medical Center, Division of Emergency Medicine, Cincinnati, Ohio/, USA
III Analítica Consultoria, São Paulo/SP, Brazil
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    "textoCompleto" => "<span class="elsevierStyleSections"><span id="cesec10" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="cestitle60">INTRODUCTION</span><p id="para110" class="elsevierStylePara elsevierViewall">Medical education has traditionally relied on apprenticeship&#44; in which students train with real patients in actual clinical settings&#46; This strategy incorporates patient-level discussions at the bedside&#44; often referred to as &#8220;rounds&#44;&#8221; which are a form of case-based learning that is vital for patient care&#46; Case-based learning is a long-established pedagogic method that usually occurs via small group discussions of patient cases in healthcare&#46; As an educational tool&#44; case-based learning is highly appreciated by learners and instructors but is associated with inconclusive results regarding its effects on learning compared with other strategies <a class="elsevierStyleCrossRef" href="#bib1">1</a>&#46; Still&#44; case-based learning offers certain advantages over didactic learning&#44; including reflective observation and the opportunity for active experimentation&#44; both of which are key aspects of experiential learning <a class="elsevierStyleCrossRef" href="#bib2">2</a>&#46;</p><p id="para120" class="elsevierStylePara elsevierViewall">Simulation is a technique used to replace or amplify real experiences using guided experiences that evoke or replicate substantial aspects of the real world in a fully interactive manner <a class="elsevierStyleCrossRef" href="#bib3">3</a>&#46; Recent movement toward decreased orientation times&#44; work-hour restrictions for residents&#44; and an increased commitment to patient safety have limited the opportunities for patient encounters and thus constitute a strong argument for simulation <a class="elsevierStyleCrossRef" href="#bib3">4</a>&#8211;<a class="elsevierStyleCrossRef" href="#bib6">6</a>&#46; In fact&#44; simulation has been increasingly used to boost the growth of learner knowledge&#44; to provide controlled and safe practice opportunities and to shape the acquisition of skills <a class="elsevierStyleCrossRef" href="#bib7">7</a>&#46; There are several types of simulators&#44; ranging from very simple ones to highly advanced computer-controlled simulators&#44; and the fidelity of the simulation depends on how close the simulation is to reality <a class="elsevierStyleCrossRef" href="#bib8">8</a>&#46; Simulation is especially of use for pediatric emergencies because critical events are infrequent&#44; yet patients have good outcomes if correctly managed <a class="elsevierStyleCrossRef" href="#bib8">8</a>&#46;</p><p id="para130" class="elsevierStylePara elsevierViewall">Simulation has been shown to be an effective training method&#44; with large effects on knowledge&#44; skills and behavioral outcomes <a class="elsevierStyleCrossRef" href="#bib9">9</a>&#46; Multiple studies have also compared non-simulation-based teaching methods with simulation-based medical education <a class="elsevierStyleCrossRef" href="#bib10">10</a>&#8211;<a class="elsevierStyleCrossRef" href="#bib14">14</a>&#44; revealing small to moderate positive effects for simulation <a class="elsevierStyleCrossRef" href="#bib14">14</a>&#46; However&#44; to date&#44; there is insufficient evidence from prospective studies comparing simulation with case-based discussion&#44; and whether simulation yields higher knowledge attainment and retention than case-based discussion does is unclear&#46;</p><p id="para140" class="elsevierStylePara elsevierViewall">A vast proportion of the knowledge acquired during medical school is not retained for a long period of time&#44; especially when this knowledge is not used in daily practice <a class="elsevierStyleCrossRef" href="#bib15">15</a>&#46; For example&#44; Yang et al&#46; assessed knowledge retention after an advanced cardiac life support course &#40;ACLS&#41; and found a decay in skills and knowledge 6 months after the course&#46; However&#44; clinical experience had a positive impact on knowledge retention <a class="elsevierStyleCrossRef" href="#bib16">16</a>&#46; Thus&#44; an important strategy to increase knowledge retention is to increase clinical practice&#46; However&#44; the reduction of hospital hours for students&#44; the rarity of certain events and the ethical imperative to preserve patient safety conflict with this need&#46; Thus&#44; active learning methods such as case-based discussion and high-fidelity simulation&#44; used in parallel to patient rounds and emergencies&#44; may complement clinical practice&#44; leading to higher retention of knowledge&#46;</p><p id="para150" class="elsevierStylePara elsevierViewall">The objective of the present study was to compare high-fidelity simulation with case-based discussion for teaching medical students about pediatric emergencies&#44; as assessed by a knowledge post-test&#44; a knowledge retention test and a survey of satisfaction with the method&#46; Our hypothesis was that the same case of an infrequent type of high-acuity pediatric emergency presented as a case-based discussion or as a simulation would yield similarly immediate knowledge gain but that higher retention of knowledge and greater student satisfaction would be attained with the simulation-based learning method&#46;</p></span><span id="cesec20" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="cestitle70">MATERIALS AND METHODS</span><p id="para160" class="elsevierStylePara elsevierViewall">We conducted a non-randomized controlled trial of simulation-based teaching compared with case-based discussion among medical students using a pre-test&#44; a post-test and a retention test &#40;4&#8211;6 months later&#41; via multiple-choice questionnaires &#40;MCQs&#41;&#46; Two themes &#40;anaphylaxis in a teenager and supraventricular tachycardia &#40;SVT&#41; in an infant&#41; were crossed over in the intervention&#44; producing two experimental cohorts&#58; group 1 - students experiencing a high-fidelity simulation of anaphylaxis &#40;SIM-ANA&#41; followed by an SVT case-based discussion &#40;CD-SVT&#41; and group 2 - students experiencing a high-fidelity simulation of SVT &#40;SIM-SVT&#41; followed by an anaphylaxis case-based discussion &#40;CD-ANA&#41;&#46; After each activity&#44; the students anonymously filled out a satisfaction questionnaire composed of 8 statements in 3 domains &#40;level of realism&#44; quality of instruction and overall satisfaction&#41;&#46; The statements were specifically rated using a 5-point Likert scale&#44; with scores ranging from 1&#8211;5&#44; adapted from the scale described by Cheng et al&#46; <a class="elsevierStyleCrossRef" href="#bib17">17</a>&#46;</p><p id="para170" class="elsevierStylePara elsevierViewall">The voluntary intervention was offered to all 174 sixth-year &#40;the final year in Brazilian medical education&#41; medical students of the Faculdade de Medicina da Universidade de S&#227;o Paulo &#40;FMUSP-University of S&#227;o Paulo Medical School&#41; during their first-semester rotation clerkship in pediatrics &#40;emergency department &#40;ED&#41; or pediatric ward&#41; in 2012&#46; Generally&#44; six groups of 13&#8211;16 students each rotate every semester in each specialty&#46; In the current study&#44; as the groups were already pre-assigned by convenience prior to their rotation&#44; they were not randomized&#46; Student demographics were obtained&#44; including information that the investigating team thought could alter performance&#46;</p><p id="para180" class="elsevierStylePara elsevierViewall">Anaphylaxis and SVT were chosen as themes because they are typical of but not exclusive to pediatric emergency&#44; rare&#44; and potentially fatal&#44; as well as because they require specific knowledge and swift action to be correctly managed <a class="elsevierStyleCrossRef" href="#bib18">18</a>&#8211;<a class="elsevierStyleCrossRef" href="#bib21">21</a>&#46; During their pediatric emergency rotation&#44; students are assigned shifts in which they care for pediatric patients in the ED while directly supervised by attending physicians and faculty&#46; The students also attend multiple lectures on diverse emergency themes and receive training in medical procedures&#44; basic life support and pediatric advanced life support in a skills laboratory supervised by faculty&#46; Neither theme used in the present project had been addressed in a specific lecture during the regular clerkship&#46;</p><p id="para190" class="elsevierStylePara elsevierViewall">Learning objectives were defined for anaphylaxis and SVT&#44; and one scenario for each theme was constructed&#46; <a class="elsevierStyleCrossRef" href="#tbl1">Table 1</a> summarizes the instructional design for both interventions&#44; which was based on Chiniara&#39;s framework for instructional design in simulation <a class="elsevierStyleCrossRef" href="#bib22">22</a> and Cook&#39;s levels of instructional design <a class="elsevierStyleCrossRef" href="#bib23">23</a>&#46;</p><elsevierMultimedia ident="tbl1"></elsevierMultimedia><p id="para200" class="elsevierStylePara elsevierViewall">The pre-test was composed of 14 MCQs&#44; with 7 for each theme&#46; The post-test was composed of 20 MCQs&#44; including the original 14 pre-test questions and 3 additional questions for each theme&#46; Finally&#44; the retention test was composed of 26 MCQs&#44; including the 20 post-test questions and 3 additional questions for each theme&#46; Based on the learning objectives&#44; 30 questions were developed by pediatric emergency physicians who were blinded to the scenarios&#46; These questions were then piloted by medical students in a pre-study phase&#44; with assessment of face&#44; content and construct validity&#44; and the questions were finalized according to an item response analysis for reliability&#46; The order of the questions was changed between tests&#44; and the additional questions mentioned above were added to control for learning with the tests themselves <a class="elsevierStyleCrossRef" href="#bib24">24</a>&#44;<a class="elsevierStyleCrossRef" href="#bib25">25</a>&#46; The participants received feedback on the test results only after the retention test&#46;</p><p id="para210" class="elsevierStylePara elsevierViewall">Our study was conducted on a convenience sample of 174 sixth-year medical students&#46; Preliminary data collected during instrument development with 20 students from the previous year&#39;s class showed a mean score of 7&#46;7 on the retention test&#44; with a standard deviation &#40;SD&#41; of 1&#46;8&#46; We calculated that if 50 students &#40;approximately 60&#37; of the students&#41; participated in each arm&#44; assuming a two-sided significance level of 0&#46;05 and an SD of 2&#44; we would have 90&#37; power to detect a difference of 0&#46;65 in our retention mean &#40;a 5&#37; improvement in scores&#41;&#46;</p><p id="para220" class="elsevierStylePara elsevierViewall">Test results were compared using t-tests for equality of means of independent samples&#46; The mean results were specifically compared between the groups for each test&#46; The satisfaction survey results were analyzed for each statement using the paired-samples test&#46; In addition&#44; Pearson correlation analysis was performed on the demographic and educational characteristics and test results to assess possible differences between students&#46; The models used for analysis were those present in Statistical Package for the Social Sciences &#40;SPSS&#41; v18&#46;</p><span id="cesec30" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="cestitle80">Ethics</span><p id="para230" class="elsevierStylePara elsevierViewall">The institutional review board of Faculdade de Medicina da Universidade de S&#227;o Paulo approved this study&#46;</p></span></span><span id="cesec40" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="cestitle90">RESULTS</span><p id="para240" class="elsevierStylePara elsevierViewall">Of the 174 students&#44; 163 &#40;93&#46;6&#37;&#41; agreed to participate&#44; and 124 &#40;71&#46;2&#37;&#41; filled in the satisfaction survey for case-based discussion and high-fidelity simulation&#46; In total&#44; 108 &#40;66&#46;3&#37;&#41; students completed all steps of the study &#40;high-fidelity simulation&#44; case-based discussion&#44; pre-test&#44; post-test and retention test&#41;&#44; including 43 in group 1 &#40;SIM-ANA&#47;CD-SVT&#41; and 65 in group 2 &#40;CD-ANA&#47;SIM-SVT&#41;&#44; as shown in <a class="elsevierStyleCrossRef" href="#fig1">Figure 1</a>&#46;</p><elsevierMultimedia ident="fig1"></elsevierMultimedia><p id="para250" class="elsevierStylePara elsevierViewall"><a class="elsevierStyleCrossRef" href="#tbl2">Table 2</a> shows the comparison of demographic and educational characteristics between the groups&#59; the only educational differences were the mean performance in ED clerkship and a previous adult ED rotation&#46;</p><elsevierMultimedia ident="tbl2"></elsevierMultimedia><p id="para260" class="elsevierStylePara elsevierViewall">Knowledge improvement from the pre-test to the post-test was observed for both teaching methods across the two themes &#40;<span class="elsevierStyleItalic">p</span>&#60;0&#46;05&#41;&#46; However&#44; there were no significant differences in knowledge at the post-test or retention test between the teaching methods for either theme &#40;<a class="elsevierStyleCrossRef" href="#fig2">Figure 2</a>&#41;&#46;</p><elsevierMultimedia ident="fig2"></elsevierMultimedia><p id="para270" class="elsevierStylePara elsevierViewall">Pearson correlation analysis found no correlation between baseline demographics or educational characteristics and test results for most characteristics&#59; the only characteristic that influenced the results was the order of clerkship rotations&#46; Group 2 included 28 students who had completed their adult ED clerkship rotation &#40;comprising internal medicine&#44; trauma&#44; cardiology and neurology&#41; prior to their pediatric rotation&#46; This subgroup had higher mean pre-test scores for SVT &#40;38&#46;7&#37;&#41; than group 1 &#40;31&#46;6&#37;&#59; <span class="elsevierStyleItalic">p</span>&#61;0&#46;06&#41; and the rest of group 2 &#40;30&#46;1&#37;&#59; <span class="elsevierStyleItalic">p</span>&#61;0&#46;02&#41; did&#46; This difference was not demonstrated at the post-test&#44; with a score of 41&#46;8&#37; for this subgroup compared with 47&#46;7&#37; for group 1 &#40;<span class="elsevierStyleItalic">p</span>&#61;0&#46;16&#41; and 43&#37; for the rest of group 2 &#40;<span class="elsevierStyleItalic">p</span>&#61;0&#46;72&#41;&#44; but was again present at the retention test for SVT&#44; with a score of 46&#46;5&#37; for this subgroup compared with 39&#46;5&#37; for group 1 &#40;<span class="elsevierStyleItalic">p</span>&#61;0&#46;04&#41; and 37&#46;8&#37; for the rest of group 2 &#40;<span class="elsevierStyleItalic">p</span>&#61;0&#46;01&#41;&#46; In contrast&#44; no significant differences were found between this subgroup and the other students for the anaphylaxis theme&#46;</p><p id="para280" class="elsevierStylePara elsevierViewall">A high degree of satisfaction was reached with both methods &#40;<a class="elsevierStyleCrossRef" href="#fig3">Figure 3</a>&#41;&#46; However&#44; simulation was perceived as more realistic&#44; a more positive experience and more useful to the profession&#46; The vast majority believed that simulation should be mandatory&#44; with a mean score of 4&#46;9 &#40;out of 5&#41;&#46; Although the same person facilitated both activities&#44; instructor knowledge and enthusiasm were rated higher for simulation&#46; The greatest mean difference in ratings was for the statement &#8220;this activity got my heart pumping&#46;&#8221;</p><elsevierMultimedia ident="fig3"></elsevierMultimedia><p id="para290" class="elsevierStylePara elsevierViewall">Two statements were not significantly different between the methods&#58; one was related to ancillary exams and images&#44; which participants found to be equally helpful in both methods &#40;<span class="elsevierStyleItalic">p</span>&#61;0&#46;11&#41;&#44; and the other was related to the learning environment&#44; which was considered to be non-threatening for both methods &#40;<span class="elsevierStyleItalic">p</span>&#61;0&#46;47&#41;&#46;</p></span><span id="cesec50" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="cestitle100">DISCUSSION</span><p id="para300" class="elsevierStylePara elsevierViewall">In this population of medical students&#44; we found no significant differences in immediate knowledge gain or retention when comparing high-fidelity simulation with case-based discussion&#46; In particular&#44; both methods showed improved post-test scores for both themes &#40;anaphylaxis and SVT&#41;&#44; and these scores were maintained over time&#46; However&#44; satisfaction was higher with the simulation method&#46;</p><p id="para310" class="elsevierStylePara elsevierViewall">In a systematic review and meta-analysis of simulation studies&#44; Cook et al&#46; reported a small to moderate effect of simulation compared with other instruction methods <a class="elsevierStyleCrossRef" href="#bib14">14</a>&#46; In our study&#44; each group experienced one high-fidelity simulation and one case-based discussion&#44; and as a single intervention&#44; case-based discussion did not appear to be more effective&#46; Similar results were shown when a one-time simulation-based workshop was compared with a case-based workshop for continuing medical education for internal medicine faculty and resident physicians <a class="elsevierStyleCrossRef" href="#bib26">26</a>&#46; However&#44; integrating multiple simulations into a curriculum appears to have a measurable effect on knowledge gain <a class="elsevierStyleCrossRef" href="#bib10">10</a>&#46; Due to the nature of active learning&#44; in the current study&#44; the scenarios were slightly more demanding of the students&#39; previous knowledge than most of the activities in the regular curriculum&#44; which could have altered retention&#46; The highest scores in our study were in the 60&#37; range&#44; so there was definite room for improvement among the students on the topics of both SVT and anaphylaxis&#46; If multiple&#44; similar simulations and&#47;or case-based discussions had been utilized&#44; the students&#39; knowledge might have increased&#44; and at a certain point&#44; a difference might have been shown between the methods&#46; This concept was demonstrated in a cohort of third-year medical students allocated to simulation of septic shock and case-based discussion of cardiogenic shock or vice versa&#44; in which the students demonstrated superior understanding of shock after a simulation experience&#44; regardless of the type of shock discussed <a class="elsevierStyleCrossRef" href="#bib27">27</a>&#46; Additionally&#44; in a week-long acute-care course&#44; fourth-year medical students randomized to simulation performed better than students randomized to problem-based learning did&#44; as measured by performance checklists <a class="elsevierStyleCrossRef" href="#bib28">28</a>&#46;</p><p id="para320" class="elsevierStylePara elsevierViewall">Satisfaction was high for both methods but was significantly higher for simulation&#46; These results were not unexpected&#44; as satisfaction with simulation has been consistently shown <a class="elsevierStyleCrossRef" href="#bib29">29</a>&#46; In the present study&#44; simulation was rated as being closer to reality and as causing an increased heart rate while remaining a non-threatening learning experience&#46; This is exactly the response that one would hope for within simulation-based training&#46; Adult learning theory states that effective practice-based learning occurs when individuals relate their learning experience to their actual practice and when the experience causes a significant change in their body state to promote reflection&#44; without being so stressful as to impede learning <a class="elsevierStyleCrossRef" href="#bib4">4</a>&#46; Similar results were shown in a month-long crossover study of curriculum format&#44; in which fourth-year medical students felt that simulation was more stressful but also more enjoyable&#44; more stimulating and closer to the actual setting than group discussions were <a class="elsevierStyleCrossRef" href="#bib10">10</a>&#46; As the average student entering medical school becomes more tech savvy&#44; it will be imperative to align educational formats with students&#39; learning styles and preferences&#46;</p><p id="para330" class="elsevierStylePara elsevierViewall">Although not formally measured by this study&#44; the faculty were clearly enthusiastic about the active learning methods used in this project&#44; resulting in plans to incorporate both simulations and case-based discussions into the regular curriculum&#46; However&#44; as our results show similar effectiveness for both methods in terms of knowledge acquisition and retention&#44; one must consider the significantly higher cost and work associated with simulation when planning a learning activity&#46; A reasonable approach would be to use simulation only when the learning objectives include technical and non-technical skills and behaviors&#44; whereas case-based discussion should be prioritized when the objectives are mainly knowledge based&#46;</p><p id="para340" class="elsevierStylePara elsevierViewall">In this study&#44; in the subgroup with a previous clerkship rotation in the adult ED&#44; higher pre-test scores and knowledge retention were found for SVT&#46; However&#44; it is unclear whether this result was an effect of non-randomization or if the previous exposure to emergencies allowed the group to relate the simulation to their experience to better retain knowledge&#44; as clinical experience has been linked to better knowledge retention and improved skills after simulation <a class="elsevierStyleCrossRef" href="#bib16">16</a>&#46;</p><p id="para350" class="elsevierStylePara elsevierViewall">We used the same instructor for simulation and case-based discussion&#44; which can be viewed as a limitation&#46; We addressed this limitation by having the exact same scenario presented&#46; We also added one item to the satisfaction survey to evaluate the instructor&#39;s enthusiasm and knowledge&#46; Although there was a difference in this item&#44; with a better rating for simulation &#40;4&#46;86&#41; than for case-based discussions &#40;4&#46;72&#41;&#44; the rating was high in both instances&#46; Furthermore&#44; having the same instructor makes comparing interventions&#44; rather than facilitators&#44; possible&#46;</p><p id="para360" class="elsevierStylePara elsevierViewall">This study has certain limitations&#46; First&#44; we were not able to randomize our students&#46; However&#44; as the baseline demographics were similar between the groups&#44; we do not feel that significant bias was introduced by the group allocation&#46; Second&#44; due to the voluntary nature of this study and the need to measure retention after 4&#8211;6 months&#44; we had a high &#40;33&#46;7&#37;&#41; loss to follow-up&#44; which potentially introduced bias and might have influenced the findings&#46; This possible issue was minimized by the fact that we still analyzed a large number of subjects that was above the calculated sample size&#46; Third&#44; the results are representative of a small cohort within a single medical school and thus cannot be safely validated externally&#46; Fourth&#44; there is a limitation regarding the strength of the intervention&#46; The number of hours of simulation has been specifically linked to learning gains <a class="elsevierStyleCrossRef" href="#bib30">30</a>&#44; so as discussed above&#44; a one-time high-fidelity simulation and a one-time case-based discussion might not be enough to generate a difference in knowledge&#44; whereas a series of simulations and case-based discussions potentially could do so&#46; Finally&#44; this study did not address clinical performance &#40;Kirkpatrick level 4&#41; or team-based skills &#40;level 2b&#41; and behaviors &#40;level 3&#41; <a class="elsevierStyleCrossRef" href="#bib31">31</a>&#46; However&#44; as medical students are not the sole healthcare providers responsible for patients and management decisions are routinely vetted by more senior physicians&#44; it was unreasonable to assess clinical outcomes in this study&#46; In any case&#44; future studies would benefit from measuring team-based skills and behaviors&#44; which are areas in which we would expect higher gains with simulation <a class="elsevierStyleCrossRef" href="#bib32">32</a>&#46;</p><p id="para370" class="elsevierStylePara elsevierViewall">Reflecting on our results and study limitations&#44; an appropriate next step would be to integrate multiple simulations and case-based discussions into our pediatric emergency clerkship curriculum and to prospectively evaluate groups randomized to each method regarding satisfaction&#44; knowledge gains and both technical and non-technical skills and behaviors&#46;</p><p id="para380" class="elsevierStylePara elsevierViewall">In conclusion&#44; as a single teaching intervention&#44; simulation is not significantly different from case-based discussion in terms of acquisition and retention of knowledge&#46; However&#44; greater satisfaction was found for simulation&#44; showing a measurable benefit of simulation compared with case-based discussion&#46;</p></span><span id="cesec60" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="cestitle110">AUTHOR CONTRIBUTIONS</span><p id="para390" class="elsevierStylePara elsevierViewall">Couto TB conceived the study&#44; participated in its design and coordination&#44; and drafted the manuscript&#46; Farhat SC and Schvartsman C participated in the design of the study and helped to interpret the data and draft the manuscript&#46; Olsen O participated in the design of the study and performed the statistical analysis&#46; Geis GL performed the data analysis and interpretation and helped to draft the manuscript&#46; All authors read&#44; revised and approved the final manuscript&#46;</p></span></span>"
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        1 => array:2 [
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          "titulo" => "INTRODUCTION"
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        2 => array:3 [
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          "titulo" => "MATERIALS AND METHODS"
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          "titulo" => "RESULTS"
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          "titulo" => "AUTHOR CONTRIBUTIONS"
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          "identificador" => "xack639278"
          "titulo" => "ACKNOWLEDGMENTS"
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        7 => array:1 [
          "titulo" => "REFERENCES"
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    "pdfFichero" => "main.pdf"
    "tienePdf" => true
    "fechaRecibido" => "2014-10-15"
    "fechaAceptado" => "2015-03-05"
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      "en" => array:1 [
        0 => array:4 [
          "clase" => "keyword"
          "titulo" => "KEYWORDS"
          "identificador" => "xpalclavsec1582331"
          "palabras" => array:6 [
            0 => "Patient Simulation"
            1 => "Problem-Based Learning"
            2 => "Medical Education"
            3 => "Undergraduate Education"
            4 => "Pediatrics"
            5 => "Comparative Study"
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        "resumen" => "<span id="ceabs10" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="cestitle10">OBJECTIVE&#58;</span><p id="spara60" class="elsevierStyleSimplePara elsevierViewall">To compare high-fidelity simulation with case-based discussion for teaching medical students about pediatric emergencies&#44; as assessed by a knowledge post-test&#44; a knowledge retention test and a survey of satisfaction with the method&#46;</p></span> <span id="ceabs20" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="cestitle20">METHODS&#58;</span><p id="spara70" class="elsevierStyleSimplePara elsevierViewall">This was a non-randomized controlled study using a crossover design for the methods&#44; as well as multiple-choice questionnaire tests and a satisfaction survey&#46; Final-year medical students were allocated into two groups&#58; group 1 participated in an anaphylaxis simulation and a discussion of a supraventricular tachycardia case&#44; and conversely&#44; group 2 participated in a discussion of an anaphylaxis case and a supraventricular tachycardia simulation&#46; Students were tested on each theme at the end of their rotation &#40;post-test&#41; and 4&#8211;6 months later &#40;retention test&#41;&#46;</p></span> <span id="ceabs30" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="cestitle30">RESULTS&#58;</span><p id="spara80" class="elsevierStyleSimplePara elsevierViewall">Most students &#40;108&#44; or 66&#46;3&#37;&#41; completed all of the tests&#46; The mean scores for simulation versus case-based discussion were respectively 43&#46;6&#37; versus 46&#46;6&#37; for the anaphylaxis pre-test &#40;<span class="elsevierStyleItalic">p</span>&#61;0&#46;42&#41;&#44; 63&#46;5&#37; versus 67&#46;8&#37; for the post-test &#40;<span class="elsevierStyleItalic">p</span>&#61;0&#46;13&#41; and 61&#46;5&#37; versus 65&#46;5&#37; for the retention test &#40;<span class="elsevierStyleItalic">p</span>&#61;0&#46;19&#41;&#46; Additionally&#44; the mean scores were respectively 33&#46;9&#37; versus 31&#46;6&#37; for the supraventricular tachycardia pre-test &#40;<span class="elsevierStyleItalic">p</span>&#61;0&#46;44&#41;&#44; 42&#46;5&#37; versus 47&#46;7&#37; for the post-test &#40;<span class="elsevierStyleItalic">p</span>&#61;0&#46;09&#41; and 41&#46;5&#37; versus 39&#46;5&#37; for the retention test &#40;<span class="elsevierStyleItalic">p</span>&#61;0&#46;47&#41;&#46; For both themes&#44; there was improvement between the pre-test and the post-test &#40;<span class="elsevierStyleItalic">p</span>&#60;0&#46;05&#41;&#44; and no significant difference was observed between the post-test and the retention test &#40;<span class="elsevierStyleItalic">p</span>&#62;0&#46;05&#41;&#46; Moreover&#44; the satisfaction survey revealed a preference for simulation &#40;<span class="elsevierStyleItalic">p</span>&#60;0&#46;001&#41;&#46;</p></span> <span id="ceabs40" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="cestitle40">CONCLUSION&#58;</span><p id="spara90" class="elsevierStyleSimplePara elsevierViewall">As a single intervention&#44; simulation is not significantly different from case-based discussion in terms of acquisition and retention of knowledge but is superior in terms of student satisfaction&#46;</p></span>"
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        "nota" => "<p class="elsevierStyleNotepara" id="cenpara10">No potential conflict of interest was reported&#46;</p>"
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          "en" => "<p id="spara10" class="elsevierStyleSimplePara elsevierViewall">Student participation&#46;</p>"
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          "en" => "<p id="spara20" class="elsevierStyleSimplePara elsevierViewall">Pretest&#44; post-test and retention test results &#40;mean scores&#41; for each theme among the medical students&#44; stratified by the teaching method&#46;</p>"
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          "en" => "<p id="spara30" class="elsevierStyleSimplePara elsevierViewall">Satisfaction survey for each teaching method &#40;&#42;<span class="elsevierStyleItalic">p</span>&#60;0&#46;001&#41;&#46;</p>"
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          "leyenda" => "<p id="tfn1" class="elsevierStyleSimplePara elsevierViewall">&#42;Same scenario&#47;case history and physical exam findings presented&#44; same images and ancillary exam results provided</p>"
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                  <table border="0" frame="\n
                  \t\t\t\t\tvoid\n
                  \t\t\t\t" class=""><thead title="thead"><tr title="table-row"><th class="td" title="\n
                  \t\t\t\t\ttable-head\n
                  \t\t\t\t  " align="left" valign="middle" scope="col">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t\t\t</th><th class="td" title="\n
                  \t\t\t\t\ttable-head\n
                  \t\t\t\t  " align="center" valign="middle" scope="col">Simulation&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t\t\t</th><th class="td" title="\n
                  \t\t\t\t\ttable-head\n
                  \t\t\t\t  " align="center" valign="middle" scope="col">Case-based discussion&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="middle">Level 1&#58; Instructional medium&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="middle">Simulation&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="middle">Face-to-face&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="middle">Level 2&#58; Configuration&#47;Simulation modality&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="middle">Simulated clinical immersion&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="middle">Small group &#40;13&#8211;16 medical students&#41; discussion&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="middle">Level 3&#58; Instructional method&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="middle">Instructor-based learning simulation &#40;led by a pediatric emergency physician&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="middle">Case discussion of anaphylaxis in a teenager or SVT in an infant<a class="elsevierStyleCrossRef" href="#tfn1">&#42;</a> &#40;led by a pediatric emergency physician&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="middle">Level 4&#58; Presentation&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="middle"><ul class="elsevierStyleList" id="celist10"><li class="elsevierStyleListItem" id="celistitem10"><span class="elsevierStyleLabel">&#8226;</span><p id="para10" class="elsevierStylePara elsevierViewall">Location&#58; FMUSP skills laboratory&#44; simulating the ED resuscitation area &#40;equipment and medications provided&#41;&#44; and debriefing room</p></li><li class="elsevierStyleListItem" id="celistitem20"><span class="elsevierStyleLabel">&#8226;</span><p id="para20" class="elsevierStylePara elsevierViewall">Fidelity&#58; High-fidelity</p></li><li class="elsevierStyleListItem" id="celistitem30"><span class="elsevierStyleLabel">&#8226;</span><p id="para30" class="elsevierStylePara elsevierViewall">Type of simulator&#58; SimMan&#174; or SimBaby&#174; &#40;Laerdal Medical&#41;</p></li><li class="elsevierStyleListItem" id="celistitem40"><span class="elsevierStyleLabel">&#8226;</span><p id="para40" class="elsevierStylePara elsevierViewall">Scenario&#58; Anaphylaxis in a teenager or SVT in an infant<a class="elsevierStyleCrossRef" href="#tfn1">&#42;</a> &#40;10&#8211;15 min&#41;</p></li><li class="elsevierStyleListItem" id="celistitem50"><span class="elsevierStyleLabel">&#8226;</span><p id="para50" class="elsevierStylePara elsevierViewall">Feedback&#58; Video-assisted immediate debriefing &#40;20 min&#41;</p></li><li class="elsevierStyleListItem" id="celistitem60"><span class="elsevierStyleLabel">&#8226;</span><p id="para60" class="elsevierStylePara elsevierViewall">Team composition&#58; 4&#8211;8 medical students assigned to different roles</p></li><li class="elsevierStyleListItem" id="celistitem70"><span class="elsevierStyleLabel">&#8226;</span><p id="para70" class="elsevierStylePara elsevierViewall">Images and ancillary exam results provided upon request<a class="elsevierStyleCrossRef" href="#tfn1">&#42;</a></p></li></ul>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="middle"><ul class="elsevierStyleList" id="celist20"><li class="elsevierStyleListItem" id="celistitem80"><span class="elsevierStyleLabel">&#8226;</span><p id="para80" class="elsevierStylePara elsevierViewall">Location&#58; FMUSP skills laboratory debriefing room</p></li><li class="elsevierStyleListItem" id="celistitem90"><span class="elsevierStyleLabel">&#8226;</span><p id="para90" class="elsevierStylePara elsevierViewall">Duration&#58; 45&#8211;60 min</p></li><li class="elsevierStyleListItem" id="celistitem100"><span class="elsevierStyleLabel">&#8226;</span><p id="para100" class="elsevierStylePara elsevierViewall">PowerPoint&#174; with history&#44; physical exam results&#44; images and ancillary exam results&#44; as needed during the discussion<a class="elsevierStyleCrossRef" href="#tfn1">&#42;</a></p></li></ul>&nbsp;\t\t\t\t\t\t\n
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          "en" => "<p id="spara40" class="elsevierStyleSimplePara elsevierViewall">Comparison of the instructional design for the two methods&#46;</p>"
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          "leyenda" => "<p id="tfn2" class="elsevierStyleSimplePara elsevierViewall">&#42;paired t-test&#44; <span class="elsevierStyleItalic">p</span>&#60;0&#46;05&#44; 95&#37; CI</p>"
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                  \t\t\t\t  " align="center" valign="middle" scope="col">Group 1 &#40;n&#61;43&#41;&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t  " colspan="2" align="center" valign="middle" scope="col">Group 2 &#40;n&#61;65&#41;</th></tr></thead><tbody title="tbody"><tr title="table-row"><td class="td" title="\n
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                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="middle">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n
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                  \t\t\t\t  " align="left" valign="middle"><span class="elsevierStyleHsp" style=""></span>Internal medicine or pediatrics&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t  " colspan="2" align="center" valign="middle">18&#46;6&#37;</td><td class="td" title="\n
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                  \t\t\t\t  " align="center" valign="middle">12&#46;3&#37;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n
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                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " colspan="2" align="center" valign="middle">20&#46;9&#37;</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="middle">12&#46;3&#37;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n
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                  \t\t\t\t  " align="left" valign="middle"><span class="elsevierStyleHsp" style=""></span>Other&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t  " colspan="2" align="center" valign="middle">27&#46;9&#37;</td><td class="td" title="\n
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                  \t\t\t\t  " align="center" valign="middle">43&#46;1&#37;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n
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                  \t\t\t\t  " align="left" valign="middle"><span class="elsevierStyleHsp" style=""></span>Did not know&#47;Did not answer&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t  " colspan="2" align="center" valign="middle">32&#46;6&#37;</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="middle">32&#46;3&#37;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n
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                  \t\t\t\t  " colspan="2" align="left" valign="middle"></td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="middle">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n
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                  \t\t\t\t  " colspan="2" align="center" valign="middle">51&#46;2&#37;</td><td class="td" title="\n
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                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="middle">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n
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                  \t\t\t\t  " colspan="2" align="center" valign="middle">76&#46;7&#37;</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="middle">70&#46;8&#37;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="middle"><span class="elsevierStyleHsp" style=""></span>26&#8211;29 years&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " colspan="2" align="center" valign="middle">20&#46;9&#37;</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="middle">24&#46;6&#37;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="middle"><span class="elsevierStyleHsp" style=""></span>&#8805;30 years&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " colspan="2" align="center" valign="middle">2&#46;4&#37;</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="middle">4&#46;6&#37;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n
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                  \t\t\t\t  " colspan="2" align="left" valign="middle"></td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="middle">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n
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                  \t\t\t\t  " align="left" valign="middle"><span class="elsevierStyleHsp" style=""></span>None&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " colspan="2" align="center" valign="middle">88&#46;4&#37;</td><td class="td" title="\n
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                  \t\t\t\t  " align="center" valign="middle">78&#46;5&#37;&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " colspan="2" align="center" valign="middle">11&#46;6&#37;</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="middle">21&#46;5&#37;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n
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                  \t\t\t\t  " colspan="2" align="left" valign="middle"></td><td class="td" title="\n
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                  \t\t\t\t  " align="left" valign="middle">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n
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                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " colspan="2" align="center" valign="middle">8&#46;5</td><td class="td" title="\n
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                  \t\t\t\t  " align="center" valign="middle">8&#46;8<a class="elsevierStyleCrossRef" href="#tfn2">&#42;</a>&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t  " colspan="2" align="left" valign="middle"></td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="middle">&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t  " align="center" valign="middle">8&#46;7&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t  " align="center" valign="middle">0&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " colspan="2" align="center" valign="middle">28<a class="elsevierStyleCrossRef" href="#tfn2">&#42;</a></td></tr></tbody></table>
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          "en" => "<p id="spara50" class="elsevierStyleSimplePara elsevierViewall">Demographic and educational characteristics&#46;</p>"
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            0 => array:3 [
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                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "The effectiveness of case-based learning in health professional education&#46; A BEME systematic review&#58; BEME Guide No&#46; 23"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => """
                              JE Thistlethwaite \n
                              \t\t\t\t\t\t\t\t
                              """
                            1 => """
                              D Davies \n
                              \t\t\t\t\t\t\t\t
                              """
                            2 => """
                              S Ekeocha \n
                              \t\t\t\t\t\t\t\t
                              """
                            3 => """
                              JM Kidd \n
                              \t\t\t\t\t\t\t\t
                              """
                            4 => """
                              C MacDougall \n
                              \t\t\t\t\t\t\t\t
                              """
                            5 => """
                              P Matthews \n
                              \t\t\t\t\t\t\t\t
                              """
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:2 [
                    0 => array:2 [
                      "doi" => "10.3109/0142159X.2012.680939"
                      "Revista" => array:7 [
                        "tituloSerie" => "Med Teach"
                        "fecha" => "2012"
                        "volumen" => "34"
                        "numero" => "6"
                        "paginaInicial" => "e421"
                        "paginaFinal" => "e444"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/22578051"
                            "web" => "Medline"
                          ]
                        ]
                      ]
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                    1 => array:2 [
                      "doi" => "10.3109/0142159X.2012.680939"
                      "WWW" => array:1 [
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                ]
              ]
            ]
            1 => array:3 [
              "identificador" => "bib2"
              "etiqueta" => "2"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Experiential learning &#58; experience as the source of learning and development"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:1 [
                            0 => """
                              DA Kolb \n
                              \t\t\t\t\t\t\t\t
                              """
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Libro" => array:5 [
                        "fecha" => "1984"
                        "paginaInicial" => "xiii"
                        "paginaFinal" => "x256"
                        "editorial" => "Prentice-Hall"
                        "editorialLocalizacion" => "Englewood Cliffs&#44; NJ"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            2 => array:3 [
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              "etiqueta" => "3"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "The future vision of simulation in healthcare"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:1 [
                            0 => """
                              DM Gaba \n
                              \t\t\t\t\t\t\t\t
                              """
                          ]
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                      ]
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                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1097/01.SIH.0000258411.38212.32"
                      "Revista" => array:7 [
                        "tituloSerie" => "Simul Healthc"
                        "fecha" => "2007 Summer"
                        "volumen" => "2"
                        "numero" => "2"
                        "paginaInicial" => "126"
                        "paginaFinal" => "135"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/19088617"
                            "web" => "Medline"
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                    0 => array:2 [
                      "titulo" => "Theoretical foundations of learning through simulation"
                      "autores" => array:1 [
                        0 => array:2 [
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                          "autores" => array:3 [
                            0 => """
                              JJ Zigmont \n
                              \t\t\t\t\t\t\t\t
                              """
                            1 => """
                              LJ Kappus \n
                              \t\t\t\t\t\t\t\t
                              """
                            2 => """
                              SN Sudikoff \n
                              \t\t\t\t\t\t\t\t
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                      "doi" => "10.1053/j.semperi.2011.01.002"
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                        "tituloSerie" => "Semin Perinatol"
                        "fecha" => "2011"
                        "volumen" => "35"
                        "numero" => "2"
                        "paginaInicial" => "47"
                        "paginaFinal" => "51"
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                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/21440810"
                            "web" => "Medline"
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                0 => array:2 [
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                    0 => array:2 [
                      "titulo" => "More students and less patients&#58; the squeeze on medical teaching resources"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:1 [
                            0 => """
                              BJ Crotty \n
                              \t\t\t\t\t\t\t\t
                              """
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                  "host" => array:1 [
                    0 => array:1 [
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                        "tituloSerie" => "Med J Aust"
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                        "volumen" => "183"
                        "numero" => "9"
                        "paginaInicial" => "444"
                        "paginaFinal" => "445"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/16274341"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            5 => array:3 [
              "identificador" => "bib6"
              "etiqueta" => "6"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "See one&#44; do one&#44; teach one&#58; advanced technology in medical education"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:4 [
                            0 => """
                              J Vozenilek \n
                              \t\t\t\t\t\t\t\t
                              """
                            1 => """
                              JS Huff \n
                              \t\t\t\t\t\t\t\t
                              """
                            2 => """
                              M Reznek \n
                              \t\t\t\t\t\t\t\t
                              """
                            3 => """
                              JA Gordon \n
                              \t\t\t\t\t\t\t\t
                              """
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:2 [
                    0 => array:2 [
                      "doi" => "10.1197/j.aem.2004.08.003"
                      "Revista" => array:7 [
                        "tituloSerie" => "Acad Emerg Med"
                        "fecha" => "2004"
                        "volumen" => "11"
                        "numero" => "11"
                        "paginaInicial" => "1149"
                        "paginaFinal" => "1154"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/15528578"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                    1 => array:2 [
                      "doi" => "10.1197/j.aem.2004.08.003"
                      "WWW" => array:1 [
                        "link" => "http&#58;&#47;&#47;dx&#46;doi&#46;org&#47;10&#46;1197&#47;j&#46;aem&#46;2004&#46;08&#46;003"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            6 => array:3 [
              "identificador" => "bib7"
              "etiqueta" => "7"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Features and uses of high-fidelity medical simulations that lead to effective learning&#58; a BEME systematic review"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:5 [
                            0 => """
                              SB Issenberg \n
                              \t\t\t\t\t\t\t\t
                              """
                            1 => """
                              WC McGaghie \n
                              \t\t\t\t\t\t\t\t
                              """
                            2 => """
                              ER Petrusa \n
                              \t\t\t\t\t\t\t\t
                              """
                            3 => """
                              D Lee Gordon \n
                              \t\t\t\t\t\t\t\t
                              """
                            4 => """
                              RJ Scalese \n
                              \t\t\t\t\t\t\t\t
                              """
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:2 [
                    0 => array:2 [
                      "doi" => "10.1080/01421590500046924"
                      "Revista" => array:7 [
                        "tituloSerie" => "Med Teach"
                        "fecha" => "2005"
                        "volumen" => "27"
                        "numero" => "1"
                        "paginaInicial" => "10"
                        "paginaFinal" => "28"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/16147767"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                    1 => array:2 [
                      "doi" => "10.1080/01421590500046924"
                      "WWW" => array:1 [
                        "link" => "http&#58;&#47;&#47;dx&#46;doi&#46;org&#47;10&#46;1080&#47;01421590500046924"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            7 => array:3 [
              "identificador" => "bib8"
              "etiqueta" => "8"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Simulation in paediatrics&#58; An educational revolution"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:5 [
                            0 => """
                              A Cheng \n
                              \t\t\t\t\t\t\t\t
                              """
                            1 => """
                              J Duff \n
                              \t\t\t\t\t\t\t\t
                              """
                            2 => """
                              E Grant \n
                              \t\t\t\t\t\t\t\t
                              """
                            3 => """
                              N Kissoon \n
                              \t\t\t\t\t\t\t\t
                              """
                            4 => """
                              VJ Grant \n
                              \t\t\t\t\t\t\t\t
                              """
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1093/pch/12.6.465"
                      "Revista" => array:7 [
                        "tituloSerie" => "Paediatr Child Health"
                        "fecha" => "2007"
                        "volumen" => "12"
                        "numero" => "6"
                        "paginaInicial" => "465"
                        "paginaFinal" => "468"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/19030409"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            8 => array:3 [
              "identificador" => "bib9"
              "etiqueta" => "9"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Technology-enhanced simulation for health professions education&#58; a systematic review and meta-analysis"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => """
                              DA Cook \n
                              \t\t\t\t\t\t\t\t
                              """
                            1 => """
                              R Hatala \n
                              \t\t\t\t\t\t\t\t
                              """
                            2 => """
                              R Brydges \n
                              \t\t\t\t\t\t\t\t
                              """
                            3 => """
                              B Zendejas \n
                              \t\t\t\t\t\t\t\t
                              """
                            4 => """
                              JH Szostek \n
                              \t\t\t\t\t\t\t\t
                              """
                            5 => """
                              AT Wang \n
                              \t\t\t\t\t\t\t\t
                              """
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1001/jama.2011.1234"
                      "Revista" => array:7 [
                        "tituloSerie" => "JAMA"
                        "fecha" => "2011"
                        "volumen" => "306"
                        "numero" => "9"
                        "paginaInicial" => "978"
                        "paginaFinal" => "988"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/21900138"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            9 => array:3 [
              "identificador" => "bib10"
              "etiqueta" => "10"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Improved medical student satisfaction and test performance with a simulation-based emergency medicine curriculum&#58; a randomized controlled trial"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:3 [
                            0 => """
                              RP Ten Eyck \n
                              \t\t\t\t\t\t\t\t
                              """
                            1 => """
                              M Tews \n
                              \t\t\t\t\t\t\t\t
                              """
                            2 => """
                              JM Ballester \n
                              \t\t\t\t\t\t\t\t
                              """
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:2 [
                    0 => array:2 [
                      "doi" => "10.1016/j.annemergmed.2009.03.025"
                      "Revista" => array:7 [
                        "tituloSerie" => "Ann Emerg Med"
                        "fecha" => "2009"
                        "volumen" => "54"
                        "numero" => "5"
                        "paginaInicial" => "684"
                        "paginaFinal" => "691"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/19394113"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                    1 => array:2 [
                      "doi" => "10.1016/j.annemergmed.2009.03.025"
                      "WWW" => array:1 [
                        "link" => "http&#58;&#47;&#47;dx&#46;doi&#46;org&#47;10&#46;1016&#47;j&#46;annemergmed&#46;2009&#46;03&#46;025"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            10 => array:3 [
              "identificador" => "bib11"
              "etiqueta" => "11"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "A randomized controlled trial of simulation-based teaching versus traditional instruction in medicine&#58; a pilot study among clinical medical students"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:6 [
                            0 => """
                              JA Gordon \n
                              \t\t\t\t\t\t\t\t
                              """
                            1 => """
                              DW Shaffer \n
                              \t\t\t\t\t\t\t\t
                              """
                            2 => """
                              DB Raemer \n
                              \t\t\t\t\t\t\t\t
                              """
                            3 => """
                              J Pawlowski \n
                              \t\t\t\t\t\t\t\t
                              """
                            4 => """
                              WE Hurford \n
                              \t\t\t\t\t\t\t\t
                              """
                            5 => """
                              JB Cooper \n
                              \t\t\t\t\t\t\t\t
                              """
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:2 [
                    0 => array:2 [
                      "doi" => "10.1007/s10459-004-7346-7"
                      "Revista" => array:7 [
                        "tituloSerie" => "Adv Health Sci Educ Theory Pract"
                        "fecha" => "2006"
                        "volumen" => "11"
                        "numero" => "1"
                        "paginaInicial" => "33"
                        "paginaFinal" => "39"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/16583282"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                    1 => array:2 [
                      "doi" => "10.1007/s10459-004-7346-7"
                      "WWW" => array:1 [
                        "link" => "http&#58;&#47;&#47;dx&#46;doi&#46;org&#47;10&#46;1007&#47;s10459-004-7346-7"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            11 => array:3 [
              "identificador" => "bib12"
              "etiqueta" => "12"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Pharmacy student knowledge retention after completing either a simulated or written patient case"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:5 [
                            0 => """
                              SM Ray \n
                              \t\t\t\t\t\t\t\t
                              """
                            1 => """
                              DR Wylie \n
                              \t\t\t\t\t\t\t\t
                              """
                            2 => """
                              A Shaun Rowe \n
                              \t\t\t\t\t\t\t\t
                              """
                            3 => """
                              E Heidel \n
                              \t\t\t\t\t\t\t\t
                              """
                            4 => """
                              AS Franks \n
                              \t\t\t\t\t\t\t\t
                              """
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:2 [
                    0 => array:2 [
                      "doi" => "10.5688/ajpe76586"
                      "Revista" => array:6 [
                        "tituloSerie" => "Am J Pharm Educ"
                        "fecha" => "2012"
                        "volumen" => "76"
                        "numero" => "5"
                        "paginaInicial" => "86"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/22761527"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                    1 => array:2 [
                      "doi" => "10.5688/ajpe76586"
                      "WWW" => array:1 [
                        "link" => "http&#58;&#47;&#47;dx&#46;doi&#46;org&#47;10&#46;5688&#47;ajpe76586"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            12 => array:3 [
              "identificador" => "bib13"
              "etiqueta" => "13"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Comparison of traditional versus high-fidelity simulation in the retention of ACLS knowledge"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => """
                              BM Lo \n
                              \t\t\t\t\t\t\t\t
                              """
                            1 => """
                              AS Devine \n
                              \t\t\t\t\t\t\t\t
                              """
                            2 => """
                              DP Evans \n
                              \t\t\t\t\t\t\t\t
                              """
                            3 => """
                              DV Byars \n
                              \t\t\t\t\t\t\t\t
                              """
                            4 => """
                              OY Lamm \n
                              \t\t\t\t\t\t\t\t
                              """
                            5 => """
                              RJ Lee \n
                              \t\t\t\t\t\t\t\t
                              """
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:2 [
                    0 => array:2 [
                      "doi" => "10.1016/j.resuscitation.2011.06.017"
                      "Revista" => array:7 [
                        "tituloSerie" => "Resuscitation"
                        "fecha" => "2011"
                        "volumen" => "82"
                        "numero" => "11"
                        "paginaInicial" => "1440"
                        "paginaFinal" => "1443"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/21764498"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                    1 => array:2 [
                      "doi" => "10.1016/j.resuscitation.2011.06.017"
                      "WWW" => array:1 [
                        "link" => "http&#58;&#47;&#47;dx&#46;doi&#46;org&#47;10&#46;1016&#47;j&#46;resuscitation&#46;2011&#46;06&#46;017"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            13 => array:3 [
              "identificador" => "bib14"
              "etiqueta" => "14"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Comparative effectiveness of technology-enhanced simulation versus other instructional methods&#58; a systematic review and meta-analysis"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => """
                              DA Cook \n
                              \t\t\t\t\t\t\t\t
                              """
                            1 => """
                              R Brydges \n
                              \t\t\t\t\t\t\t\t
                              """
                            2 => """
                              SJ Hamstra \n
                              \t\t\t\t\t\t\t\t
                              """
                            3 => """
                              B Zendejas \n
                              \t\t\t\t\t\t\t\t
                              """
                            4 => """
                              JH Szostek \n
                              \t\t\t\t\t\t\t\t
                              """
                            5 => """
                              AT Wang \n
                              \t\t\t\t\t\t\t\t
                              """
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:2 [
                    0 => array:2 [
                      "doi" => "10.1097/SIH.0b013e3182614f95"
                      "Revista" => array:7 [
                        "tituloSerie" => "Simul Healthc"
                        "fecha" => "2012"
                        "volumen" => "7"
                        "numero" => "5"
                        "paginaInicial" => "308"
                        "paginaFinal" => "320"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/23032751"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                    1 => array:2 [
                      "doi" => "10.1097/SIH.0b013e3182614f95"
                      "WWW" => array:1 [
                        "link" => "http&#58;&#47;&#47;dx&#46;doi&#46;org&#47;10&#46;1097&#47;SIH&#46;0b013e3182614f95"
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                    ]
                  ]
                ]
              ]
            ]
            14 => array:3 [
              "identificador" => "bib15"
              "etiqueta" => "15"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Long-term retention of basic science knowledge&#58; a review study"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:1 [
                            0 => """
                              EJ Custers \n
                              \t\t\t\t\t\t\t\t
                              """
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:2 [
                    0 => array:2 [
                      "doi" => "10.1007/s10459-008-9101-y"
                      "Revista" => array:7 [
                        "tituloSerie" => "Adv Health Sci Educ Theory Pract"
                        "fecha" => "2010"
                        "volumen" => "15"
                        "numero" => "1"
                        "paginaInicial" => "109"
                        "paginaFinal" => "128"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/18274876"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                    1 => array:2 [
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                      "WWW" => array:1 [
                        "link" => "http&#58;&#47;&#47;dx&#46;doi&#46;org&#47;10&#46;1007&#47;s10459-008-9101-y"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            15 => array:3 [
              "identificador" => "bib16"
              "etiqueta" => "16"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "A systematic review of retention of adult advanced life support knowledge and skills in healthcare providers"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => """
                              CW Yang \n
                              \t\t\t\t\t\t\t\t
                              """
                            1 => """
                              ZS Yen \n
                              \t\t\t\t\t\t\t\t
                              """
                            2 => """
                              JE McGowan \n
                              \t\t\t\t\t\t\t\t
                              """
                            3 => """
                              HC Chen \n
                              \t\t\t\t\t\t\t\t
                              """
                            4 => """
                              WC Chiang \n
                              \t\t\t\t\t\t\t\t
                              """
                            5 => """
                              ME Mancini \n
                              \t\t\t\t\t\t\t\t
                              """
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:2 [
                    0 => array:2 [
                      "doi" => "10.1016/j.resuscitation.2012.02.027"
                      "Revista" => array:7 [
                        "tituloSerie" => "Resuscitation"
                        "fecha" => "2012"
                        "volumen" => "83"
                        "numero" => "9"
                        "paginaInicial" => "1055"
                        "paginaFinal" => "1060"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/22391016"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                    1 => array:2 [
                      "doi" => "10.1016/j.resuscitation.2012.02.027"
                      "WWW" => array:1 [
                        "link" => "http&#58;&#47;&#47;dx&#46;doi&#46;org&#47;10&#46;1016&#47;j&#46;resuscitation&#46;2012&#46;02&#46;027"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            16 => array:3 [
              "identificador" => "bib17"
              "etiqueta" => "17"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "A simulation-based acute care curriculum for pediatric emergency medicine fellowship training programs"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:4 [
                            0 => """
                              A Cheng \n
                              \t\t\t\t\t\t\t\t
                              """
                            1 => """
                              RD Goldman \n
                              \t\t\t\t\t\t\t\t
                              """
                            2 => """
                              MA Aish \n
                              \t\t\t\t\t\t\t\t
                              """
                            3 => """
                              N Kissoon \n
                              \t\t\t\t\t\t\t\t
                              """
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:2 [
                    0 => array:2 [
                      "doi" => "10.1097/PEC.0b013e3181e5841b"
                      "Revista" => array:7 [
                        "tituloSerie" => "Pediatr Emerg Care"
                        "fecha" => "2010"
                        "volumen" => "26"
                        "numero" => "7"
                        "paginaInicial" => "475"
                        "paginaFinal" => "480"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/20577139"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                    1 => array:2 [
                      "doi" => "10.1097/PEC.0b013e3181e5841b"
                      "WWW" => array:1 [
                        "link" => "http&#58;&#47;&#47;dx&#46;doi&#46;org&#47;10&#46;1097&#47;PEC&#46;0b013e3181e5841b"
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                    ]
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                ]
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            ]
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              "identificador" => "bib18"
              "etiqueta" => "18"
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                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "World Allergy Organization anaphylaxis guidelines&#58; summary"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => """
                              FE Simons \n
                              \t\t\t\t\t\t\t\t
                              """
                            1 => """
                              LR Ardusso \n
                              \t\t\t\t\t\t\t\t
                              """
                            2 => """
                              MB Bilo \n
                              \t\t\t\t\t\t\t\t
                              """
                            3 => """
                              YM El-Gamal \n
                              \t\t\t\t\t\t\t\t
                              """
                            4 => """
                              DK Ledford \n
                              \t\t\t\t\t\t\t\t
                              """
                            5 => """
                              J Ring \n
                              \t\t\t\t\t\t\t\t
                              """
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:2 [
                    0 => array:2 [
                      "doi" => "10.1016/j.jaci.2011.01.038"
                      "Revista" => array:7 [
                        "tituloSerie" => "J Allergy Clin Immunol"
                        "fecha" => "2011"
                        "volumen" => "127"
                        "numero" => "3"
                        "paginaInicial" => "587"
                        "paginaFinal" => "593"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/21377030"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                    1 => array:2 [
                      "doi" => "10.1016/j.jaci.2011.01.038"
                      "WWW" => array:1 [
                        "link" => "http&#58;&#47;&#47;dx&#46;doi&#46;org&#47;10&#46;1016&#47;j&#46;jaci&#46;2011&#46;01&#46;038"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            18 => array:3 [
              "identificador" => "bib19"
              "etiqueta" => "19"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Emergency treatment of anaphylaxis in infants and children"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:1 [
                            0 => """
                              A Cheng \n
                              \t\t\t\t\t\t\t\t
                              """
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:7 [
                        "tituloSerie" => "Paediatr Child Health"
                        "fecha" => "2011"
                        "volumen" => "16"
                        "numero" => "1"
                        "paginaInicial" => "35"
                        "paginaFinal" => "40"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/22211074"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            19 => array:3 [
              "identificador" => "bib20"
              "etiqueta" => "20"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Emergency department management of the pediatric patient with supraventricular tachycardia"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:2 [
                            0 => """
                              MD Manole \n
                              \t\t\t\t\t\t\t\t
                              """
                            1 => """
                              RA Saladino \n
                              \t\t\t\t\t\t\t\t
                              """
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1097/PEC.0b013e318032904c"
                      "Revista" => array:7 [
                        "tituloSerie" => "Pediatr Emerg Care"
                        "fecha" => "2007"
                        "volumen" => "23"
                        "numero" => "3"
                        "paginaInicial" => "176"
                        "paginaFinal" => "185"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/17413437"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            20 => array:3 [
              "identificador" => "bib21"
              "etiqueta" => "21"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Part 6&#58; electrical therapies&#58; automated external defibrillators&#44; defibrillation&#44; cardioversion&#44; and pacing&#58; 2010 American Heart Association Guidelines for Cardiopulmonary Resuscitation and Emergency Cardiovascular Care"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => """
                              MS Link \n
                              \t\t\t\t\t\t\t\t
                              """
                            1 => """
                              DL Atkins \n
                              \t\t\t\t\t\t\t\t
                              """
                            2 => """
                              RS Passman \n
                              \t\t\t\t\t\t\t\t
                              """
                            3 => """
                              HR Halperin \n
                              \t\t\t\t\t\t\t\t
                              """
                            4 => """
                              RA Samson \n
                              \t\t\t\t\t\t\t\t
                              """
                            5 => """
                              RD White \n
                              \t\t\t\t\t\t\t\t
                              """
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:2 [
                    0 => array:2 [
                      "doi" => "10.1161/CIRCULATIONAHA.110.970954"
                      "Revista" => array:7 [
                        "tituloSerie" => "Circulation"
                        "fecha" => "2010"
                        "volumen" => "122"
                        "numero" => "18 Suppl 3"
                        "paginaInicial" => "S706"
                        "paginaFinal" => "S719"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/20956222"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                    1 => array:2 [
                      "doi" => "10.1161/CIRCULATIONAHA.110.970954"
                      "WWW" => array:1 [
                        "link" => "http&#58;&#47;&#47;dx&#46;doi&#46;org&#47;10&#46;1161&#47;CIRCULATIONAHA&#46;110&#46;970954"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            21 => array:3 [
              "identificador" => "bib22"
              "etiqueta" => "22"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Simulation in healthcare&#58; a taxonomy and a conceptual framework for instructional design and media selection"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => """
                              G Chiniara \n
                              \t\t\t\t\t\t\t\t
                              """
                            1 => """
                              G Cole \n
                              \t\t\t\t\t\t\t\t
                              """
                            2 => """
                              K Brisbin \n
                              \t\t\t\t\t\t\t\t
                              """
                            3 => """
                              D Huffman \n
                              \t\t\t\t\t\t\t\t
                              """
                            4 => """
                              B Cragg \n
                              \t\t\t\t\t\t\t\t
                              """
                            5 => """
                              M Lamacchia \n
                              \t\t\t\t\t\t\t\t
                              """
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:2 [
                    0 => array:2 [
                      "doi" => "10.3109/0142159X.2012.733451"
                      "Revista" => array:7 [
                        "tituloSerie" => "Med Teach"
                        "fecha" => "2013"
                        "volumen" => "35"
                        "numero" => "8"
                        "paginaInicial" => "e1380"
                        "paginaFinal" => "e1395"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/23121247"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                    1 => array:2 [
                      "doi" => "10.3109/0142159X.2012.733451"
                      "WWW" => array:1 [
                        "link" => "http&#58;&#47;&#47;dx&#46;doi&#46;org&#47;10&#46;3109&#47;0142159X&#46;2012&#46;733451"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            22 => array:3 [
              "identificador" => "bib23"
              "etiqueta" => "23"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "The research we still are not doing&#58; an agenda for the study of computer-based learning"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:1 [
                            0 => """
                              DA Cook \n
                              \t\t\t\t\t\t\t\t
                              """
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:2 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Acad Medic"
                        "fecha" => "2005"
                        "volumen" => "80"
                        "numero" => "6"
                        "paginaInicial" => "541"
                        "paginaFinal" => "548"
                      ]
                    ]
                    1 => array:1 [
                      "WWW" => array:1 [
                        "link" => "http&#58;&#47;&#47;dx&#46;doi&#46;org&#47;10&#46;1097&#47;00001888-200506000-00005"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            23 => array:3 [
              "identificador" => "bib24"
              "etiqueta" => "24"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "The basics of item response theory"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:1 [
                            0 => """
                              FB Baker \n
                              \t\t\t\t\t\t\t\t
                              """
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Libro" => array:5 [
                        "edicion" => "2nd ed&#46;"
                        "fecha" => "2001"
                        "paginaInicial" => "vi"
                        "editorial" => "ERIC Clearinghouse on Assessment and Evaluation"
                        "editorialLocalizacion" => "College Park&#44; MD"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            24 => array:3 [
              "identificador" => "bib25"
              "etiqueta" => "25"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Design&#44; format&#44; validity and reliability of multiple choice questions for use in nursing research and education"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:3 [
                            0 => """
                              J Considine \n
                              \t\t\t\t\t\t\t\t
                              """
                            1 => """
                              M Botti \n
                              \t\t\t\t\t\t\t\t
                              """
                            2 => """
                              S Thomas \n
                              \t\t\t\t\t\t\t\t
                              """
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:2 [
                    0 => array:2 [
                      "doi" => "10.1016/s1322-7696(08)60478-3"
                      "Revista" => array:7 [
                        "tituloSerie" => "Collegian"
                        "fecha" => "2005"
                        "volumen" => "12"
                        "numero" => "1"
                        "paginaInicial" => "19"
                        "paginaFinal" => "24"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/16619900"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                    1 => array:2 [
                      "doi" => "10.1016/s1322-7696(08)60478-3"
                      "WWW" => array:1 [
                        "link" => "http&#58;&#47;&#47;dx&#46;doi&#46;org&#47;10&#46;1016&#47;S1322-7696&#40;08&#41;60478-3"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            25 => array:3 [
              "identificador" => "bib26"
              "etiqueta" => "26"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Feasibility of scenario-based simulation training versus traditional workshops in continuing medical education&#58; a randomized controlled trial"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => """
                              B Kerr \n
                              \t\t\t\t\t\t\t\t
                              """
                            1 => """
                              TL-A Hawkins \n
                              \t\t\t\t\t\t\t\t
                              """
                            2 => """
                              R Herman \n
                              \t\t\t\t\t\t\t\t
                              """
                            3 => """
                              S Barnes \n
                              \t\t\t\t\t\t\t\t
                              """
                            4 => """
                              S Kaufmann \n
                              \t\t\t\t\t\t\t\t
                              """
                            5 => """
                              K Fraser \n
                              \t\t\t\t\t\t\t\t
                              """
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:2 [
                    0 => array:1 [
                      "Revista" => array:3 [
                        "tituloSerie" => "Med Educ Online"
                        "fecha" => "2013"
                        "volumen" => "18"
                      ]
                    ]
                    1 => array:1 [
                      "WWW" => array:1 [
                        "link" => "http&#58;&#47;&#47;dx&#46;doi&#46;org&#47;10&#46;3402&#47;meo&#46;v18i0&#46;21312"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            26 => array:3 [
              "identificador" => "bib27"
              "etiqueta" => "27"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "High-fidelity simulation is superior to case-based discussion in teaching the management of shock"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:5 [
                            0 => """
                              KE Littlewood \n
                              \t\t\t\t\t\t\t\t
                              """
                            1 => """
                              AM Shilling \n
                              \t\t\t\t\t\t\t\t
                              """
                            2 => """
                              CJ Stemland \n
                              \t\t\t\t\t\t\t\t
                              """
                            3 => """
                              EB Wright \n
                              \t\t\t\t\t\t\t\t
                              """
                            4 => """
                              MA Kirk \n
                              \t\t\t\t\t\t\t\t
                              """
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:2 [
                    0 => array:2 [
                      "doi" => "10.3109/0142159X.2012.733043"
                      "Revista" => array:7 [
                        "tituloSerie" => "Med Teach"
                        "fecha" => "2013"
                        "volumen" => "35"
                        "numero" => "3"
                        "paginaInicial" => "e1003"
                        "paginaFinal" => "e1e10"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/23126242"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                    1 => array:2 [
                      "doi" => "10.3109/0142159X.2012.733043"
                      "WWW" => array:1 [
                        "link" => "http&#58;&#47;&#47;dx&#46;doi&#46;org&#47;10&#46;3109&#47;0142159X&#46;2012&#46;733043"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            27 => array:3 [
              "identificador" => "bib28"
              "etiqueta" => "28"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Simulation-based training is superior to problem-based learning for the acquisition of critical assessment and management skills&#42;"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => """
                              RH Steadman \n
                              \t\t\t\t\t\t\t\t
                              """
                            1 => """
                              WC Coates \n
                              \t\t\t\t\t\t\t\t
                              """
                            2 => """
                              YM Huang \n
                              \t\t\t\t\t\t\t\t
                              """
                            3 => """
                              R Matevosian \n
                              \t\t\t\t\t\t\t\t
                              """
                            4 => """
                              BR Larmon \n
                              \t\t\t\t\t\t\t\t
                              """
                            5 => """
                              L McCullough \n
                              \t\t\t\t\t\t\t\t
                              """
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:2 [
                    0 => array:2 [
                      "doi" => "10.1097/01.ccm.0000190619.42013.94"
                      "Revista" => array:7 [
                        "tituloSerie" => "Crit Care Med"
                        "fecha" => "2006"
                        "volumen" => "34"
                        "numero" => "1"
                        "paginaInicial" => "151"
                        "paginaFinal" => "157"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/16374169"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                    1 => array:2 [
                      "doi" => "10.1097/01.ccm.0000190619.42013.94"
                      "WWW" => array:1 [
                        "link" => "http&#58;&#47;&#47;dx&#46;doi&#46;org&#47;10&#46;1097&#47;01&#46;CCM&#46;0000190619&#46;42013&#46;94"
                      ]
                    ]
                  ]
                ]
              ]
            ]
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              "identificador" => "bib29"
              "etiqueta" => "29"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Simulation-based training in anaesthesiology&#58; a systematic review and meta-analysis"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:4 [
                            0 => """
                              GR Lorello \n
                              \t\t\t\t\t\t\t\t
                              """
                            1 => """
                              DA Cook \n
                              \t\t\t\t\t\t\t\t
                              """
                            2 => """
                              RL Johnson \n
                              \t\t\t\t\t\t\t\t
                              """
                            3 => """
                              R Brydges \n
                              \t\t\t\t\t\t\t\t
                              """
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:2 [
                    0 => array:2 [
                      "doi" => "10.1093/bja/aet414"
                      "Revista" => array:7 [
                        "tituloSerie" => "Br J Anaesth"
                        "fecha" => "2014"
                        "volumen" => "112"
                        "numero" => "2"
                        "paginaInicial" => "231"
                        "paginaFinal" => "245"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/24368556"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                    1 => array:2 [
                      "doi" => "10.1093/bja/aet414"
                      "WWW" => array:1 [
                        "link" => "http&#58;&#47;&#47;dx&#46;doi&#46;org&#47;10&#46;1093&#47;bja&#47;aet414"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            29 => array:3 [
              "identificador" => "bib30"
              "etiqueta" => "30"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Effect of practice on standardised learning outcomes in simulation-based medical education"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:4 [
                            0 => """
                              WC McGaghie \n
                              \t\t\t\t\t\t\t\t
                              """
                            1 => """
                              SB Issenberg \n
                              \t\t\t\t\t\t\t\t
                              """
                            2 => """
                              ER Petrusa \n
                              \t\t\t\t\t\t\t\t
                              """
                            3 => """
                              RJ Scalese \n
                              \t\t\t\t\t\t\t\t
                              """
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:2 [
                    0 => array:2 [
                      "doi" => "10.1111/j.1365-2929.2006.02528.x"
                      "Revista" => array:7 [
                        "tituloSerie" => "Med Educ"
                        "fecha" => "2006"
                        "volumen" => "40"
                        "numero" => "8"
                        "paginaInicial" => "792"
                        "paginaFinal" => "797"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/16869926"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                    1 => array:2 [
                      "doi" => "10.1111/j.1365-2929.2006.02528.x"
                      "WWW" => array:1 [
                        "link" => "http&#58;&#47;&#47;dx&#46;doi&#46;org&#47;10&#46;1111&#47;med&#46;2006&#46;40&#46;issue-8"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            30 => array:3 [
              "identificador" => "bib31"
              "etiqueta" => "31"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Evaluating training programs&#58; the four levels"
                      "autores" => array:1 [
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        "titulo" => "ACKNOWLEDGMENTS"
        "texto" => "<p id="para400" class="elsevierStylePara elsevierViewall">The work was supported by the Departamento de Pediatria da Faculdade de Medicina da Universidade de S&#227;o Paulo&#46; Simulations and case-based discussions were performed at the Faculdade de Medicina da Universidade de S&#227;o Paulo during students&#39; emergency pediatric rotation&#44; with no additional external funding&#46; Laerdal Medical lent SimBaby&#174; for this project&#46;</p>"
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Article information
ISSN: 18075932
Original language: English
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