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array:24 [ "pii" => "S1807593222019597" "issn" => "18075932" "doi" => "10.1590/S1807-59322011000900025" "estado" => "S300" "fechaPublicacion" => "2011-09-01" "aid" => "1959" "copyright" => "CLINICS" "copyrightAnyo" => "2011" "documento" => "article" "crossmark" => 0 "licencia" => "https://creativecommons.org/licenses/by-nc/3.0/" "subdocumento" => "crp" "cita" => "Clinics. 2011;66:1651-3" "abierto" => array:3 [ "ES" => true "ES2" => true "LATM" => true ] "gratuito" => true "lecturas" => array:1 [ "total" => 0 ] "itemSiguiente" => array:19 [ "pii" => "S1807593222019603" "issn" => "18075932" "doi" => "10.1590/S1807-59322011000900026" "estado" => "S300" "fechaPublicacion" => "2011-09-01" "aid" => "1960" "copyright" => "CLINICS" "documento" => "article" "crossmark" => 0 "licencia" => "https://creativecommons.org/licenses/by-nc/3.0/" "subdocumento" => "crp" "cita" => "Clinics. 2011;66:1655-7" "abierto" => array:3 [ "ES" => true "ES2" => true "LATM" => true ] "gratuito" => true "lecturas" => array:1 [ "total" => 0 ] "en" => array:10 [ "idiomaDefecto" => true "cabecera" => "<span class="elsevierStyleTextfn">CASE REPORT</span>" "titulo" => "Choreoathetosis after subarachnoid hemorrhage related to an aneurysm of the posterior fossa" "tienePdf" => "en" "tieneTextoCompleto" => "en" "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "1655" "paginaFinal" => "1657" ] ] "contieneTextoCompleto" => array:1 [ "en" => true ] "contienePdf" => array:1 [ "en" => true ] "resumenGrafico" => array:2 [ "original" => 0 "multimedia" => array:7 [ "identificador" => "fig1" "etiqueta" => "Figure 1" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr1.jpeg" "Alto" => 263 "Ancho" => 586 "Tamanyo" => 30284 ] ] "descripcion" => array:1 [ "en" => "<p id="spara10" class="elsevierStyleSimplePara elsevierViewall">A) Cerebral angiography at admission revealed a small saccular aneurysm of the basilar artery near the emergence of the anterior inferior cerebellar artery (AICA). B) T2-weighted Magnetic Resonance Imaging (MRI) at the one-year follow-up revealed cerebellar atrophy.</p>" ] ] ] "autores" => array:1 [ 0 => array:2 [ "autoresLista" => "Júlio Leonardo Barbosa Pereira, Lucas Alverne Freitas de Albuquerque, Mauro Cruz Machado Borgo, Gerival Vieira, Paulo Pereira Christo, Gervásio Teles C. de Carvalho" "autores" => array:6 [ 0 => array:2 [ "nombre" => "Júlio Leonardo Barbosa" "apellidos" => "Pereira" ] 1 => array:2 [ "nombre" => "Lucas Alverne Freitas" "apellidos" => "de Albuquerque" ] 2 => array:2 [ "nombre" => "Mauro Cruz Machado" "apellidos" => "Borgo" ] 3 => array:3 [ "nombre" => "Gerival" "apellidos" => "Vieira" "sufijo" => "Junior" ] 4 => array:2 [ "nombre" => "Paulo Pereira" "apellidos" => "Christo" ] 5 => array:2 [ "nombre" => "Gervásio Teles C." "apellidos" => "de Carvalho" ] ] ] ] ] "idiomaDefecto" => "en" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S1807593222019603?idApp=UINPBA00004N" "url" => "/18075932/0000006600000009/v1_202212011637/S1807593222019603/v1_202212011637/en/main.assets" ] "itemAnterior" => array:19 [ "pii" => "S1807593222019585" "issn" => "18075932" "doi" => "10.1590/S1807-59322011000900024" "estado" => "S300" "fechaPublicacion" => "2011-09-01" "aid" => "1958" "copyright" => "CLINICS" "documento" => "article" "crossmark" => 0 "licencia" => "https://creativecommons.org/licenses/by-nc/3.0/" "subdocumento" => "fla" "cita" => "Clinics. 2011;66:1645-50" "abierto" => array:3 [ "ES" => true "ES2" => true "LATM" => true ] "gratuito" => true "lecturas" => array:1 [ "total" => 0 ] "en" => array:9 [ "idiomaDefecto" => true "cabecera" => "<span class="elsevierStyleTextfn">RAPID COMMUNICATION</span>" "titulo" => "Trunk stabilization among women with chronic lower back pain: a randomized, controlled, and blinded pilot study" "tienePdf" => "en" "tieneTextoCompleto" => "en" "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "1645" "paginaFinal" => "1650" ] ] "contieneTextoCompleto" => array:1 [ "en" => true ] "contienePdf" => array:1 [ "en" => true ] "autores" => array:1 [ 0 => array:2 [ "autoresLista" => "Silvia Ferreira Andrusaitis, Guilherme Carlos Brech, Gabriela FallerVitale, Júlia Maria D′ Andréa Greve" "autores" => array:4 [ 0 => array:2 [ "nombre" => "Silvia Ferreira" "apellidos" => "Andrusaitis" ] 1 => array:2 [ "nombre" => "Guilherme Carlos" "apellidos" => "Brech" ] 2 => array:2 [ "nombre" => "Gabriela" "apellidos" => "FallerVitale" ] 3 => array:2 [ "nombre" => "Júlia Maria D′ Andréa" "apellidos" => "Greve" ] ] ] ] ] "idiomaDefecto" => "en" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S1807593222019585?idApp=UINPBA00004N" "url" => "/18075932/0000006600000009/v1_202212011637/S1807593222019585/v1_202212011637/en/main.assets" ] "en" => array:13 [ "idiomaDefecto" => true "cabecera" => "<span class="elsevierStyleTextfn">CASE REPORT</span>" "titulo" => "Paroxysmal atrial fibrillation and intermittent left bundle branch block: an unusual electrocardiographic presentation of mad honey poisoning" "tieneTextoCompleto" => true "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "1651" "paginaFinal" => "1653" ] ] "autores" => array:1 [ 0 => array:4 [ "autoresLista" => "Ayhan Saritas, Hayati Kandis, Davut Baltaci, Ismail Erdem" "autores" => array:4 [ 0 => array:4 [ "nombre" => "Ayhan" "apellidos" => "Saritas" "email" => array:1 [ 0 => "a_saritas_@hotmail.com" ] "referencia" => array:2 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">I</span>" "identificador" => "aff1" ] 1 => array:2 [ "etiqueta" => "*" "identificador" => "cor1" ] ] ] 1 => array:3 [ "nombre" => "Hayati" "apellidos" => "Kandis" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">I</span>" "identificador" => "aff1" ] ] ] 2 => array:3 [ "nombre" => "Davut" "apellidos" => "Baltaci" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">II</span>" "identificador" => "aff2" ] ] ] 3 => array:3 [ "nombre" => "Ismail" "apellidos" => "Erdem" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">III</span>" "identificador" => "aff3" ] ] ] ] "afiliaciones" => array:3 [ 0 => array:3 [ "entidad" => "Duzce University School of Medicine, Department of Emergency Medicine, Duzce, Turkey." "etiqueta" => "I" "identificador" => "aff1" ] 1 => array:3 [ "entidad" => "Duzce University School of Medicine, Department of Family Medicine, Duzce, Turkey." "etiqueta" => "II" "identificador" => "aff2" ] 2 => array:3 [ "entidad" => "Duzce University School of Medicine, Department of Cardiology, Duzce, Turkey." "etiqueta" => "III" "identificador" => "aff3" ] ] "correspondencia" => array:1 [ 0 => array:3 [ "identificador" => "cor1" "etiqueta" => "*" "correspondencia" => "Tel.: 0 380 5421390/5820" ] ] ] ] "resumenGrafico" => array:2 [ "original" => 0 "multimedia" => array:7 [ "identificador" => "fig1" "etiqueta" => "Figure 1" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr1.jpeg" "Alto" => 479 "Ancho" => 661 "Tamanyo" => 71262 ] ] "descripcion" => array:1 [ "en" => "<p id="spara10" class="elsevierStyleSimplePara elsevierViewall">Paroxysmal atrial fibrillation and intermittent left bundle branch block upon admission.</p>" ] ] ] "textoCompleto" => "<span class="elsevierStyleSections"><span id="cesec10" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="cestitle10">INTRODUCTION</span><p id="para10" class="elsevierStylePara elsevierViewall">Mad honey poisoning occurs through the intake of honey made from the nectar of Rhododendron species containing grayanotoxins, a family of lipid-soluble toxins responsible for the clinical manifestations of mad honey intoxication syndrome. These plants grow in the eastern parts of the Black Sea region of Turkey and in various other parts of the world (e.g., South America, Europe, and Japan).<a class="elsevierStyleCrossRef" href="#bib1">1</a> Previous reports concerning mad honey poisoning have generally described various degrees of atrioventricular (AV) block, sinus bradycardia, asystole, nodal rhythm with ventricular parasystole, and even acute myocardial infarction.<a class="elsevierStyleCrossRefs" href="#bib2">2,3</a> The diagnosis is often made based on a history of honey intake. We report a unique case of a patient who presented paroxysmal atrial fibrillation and intermittent left bundle branch block related to mad honey poisoning.</p></span><span id="cesec20" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="cestitle20">CASE REPORT</span><p id="para20" class="elsevierStylePara elsevierViewall">A 70-year-old man was admitted to our emergency department with weakness, palpitation, nausea and vomiting that arose from eating a few teaspoons of mad honey. He did not have any cardiovascular or systemic disease and was not taking any medication. On physical examination, he was confused, his blood pressure was 60/20 mmHg, and his heart rate was 105 beats/min. The neurological examination was normal. Upon admission, his electrocardiography revealed paroxysmal atrial fibrillation and intermittent left bundle branch block (<a class="elsevierStyleCrossRef" href="#fig1">Figure 1</a>). There was no structural cardiac abnormality found from transthoracic echocardiography. His hypotension improved rapidly after saline infusion. During observation, his rhythm returned to a normal sinus rhythm six hours after admission (<a class="elsevierStyleCrossRef" href="#fig2">Figure 2</a>), and he was discharged on the second day of his hospital stay.</p><elsevierMultimedia ident="fig1"></elsevierMultimedia><elsevierMultimedia ident="fig2"></elsevierMultimedia></span><span id="cesec30" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="cestitle30">DISCUSSION</span><p id="para30" class="elsevierStylePara elsevierViewall">Grayanotoxins are responsible for the clinical manifestations of mad honey poisoning. These toxins bind to sodium channels in the cell membrane, increasing the permeability of these channels and are thus responsible for inotropy. The signs and symptoms generally may occur within minutes and to up to two hours or more after ingestion.<a class="elsevierStyleCrossRefs" href="#bib1">1,4,5</a> Well-known clinical manifestations of mad honey poisoning include hypotension, bradycardia, arrhythmia, loss of consciousness, weakness, nausea, and vomiting. To the best of our knowledge, no case of paroxysmal atrial fibrillation and intermittent left bundle branch block associated with mad honey poisoning has previously been reported.</p></span><span id="cesec40" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="cestitle40">CONCLUSION</span><p id="para40" class="elsevierStylePara elsevierViewall">We report a case of a 70-year-old man with severe hemodynamic instability following the ingestion of mad honey and his unusual electrocardiographic manifestations: paroxysmal atrial fibrillation and intermittent left bundle branch block.</p></span></span>" "textoCompletoSecciones" => array:1 [ "secciones" => array:5 [ 0 => array:2 [ "identificador" => "cesec10" "titulo" => "INTRODUCTION" ] 1 => array:2 [ "identificador" => "cesec20" "titulo" => "CASE REPORT" ] 2 => array:2 [ "identificador" => "cesec30" "titulo" => "DISCUSSION" ] 3 => array:2 [ "identificador" => "cesec40" "titulo" => "CONCLUSION" ] 4 => array:1 [ "titulo" => "REFERENCES" ] ] ] "pdfFichero" => "main.pdf" "tienePdf" => true "multimedia" => array:2 [ 0 => array:7 [ "identificador" => "fig1" "etiqueta" => "Figure 1" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr1.jpeg" "Alto" => 479 "Ancho" => 661 "Tamanyo" => 71262 ] ] "descripcion" => array:1 [ "en" => "<p id="spara10" class="elsevierStyleSimplePara elsevierViewall">Paroxysmal atrial fibrillation and intermittent left bundle branch block upon admission.</p>" ] ] 1 => array:7 [ "identificador" => "fig2" "etiqueta" => "Figure 2" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr2.jpeg" "Alto" => 630 "Ancho" => 661 "Tamanyo" => 79583 ] ] "descripcion" => array:1 [ "en" => "<p id="spara20" class="elsevierStyleSimplePara elsevierViewall">Normal sinus rhythm 6 hours after admission.</p>" ] ] ] "bibliografia" => array:2 [ "titulo" => "REFERENCES" "seccion" => array:1 [ 0 => array:2 [ "identificador" => "cebibsec10" "bibliografiaReferencia" => array:5 [ 0 => array:3 [ "identificador" => "bib1" "etiqueta" => "1" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Wild flowers and mad honey" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:5 [ 0 => """ A Gunduz \n \t\t\t\t\t\t\t\t """ 1 => """ H Bostan \n \t\t\t\t\t\t\t\t """ 2 => """ S Turedi \n \t\t\t\t\t\t\t\t """ 3 => """ I Nuhoğlu \n \t\t\t\t\t\t\t\t """ 4 => """ T Patan \n \t\t\t\t\t\t\t\t """ ] ] ] ] ] "host" => array:2 [ 0 => array:2 [ "doi" => "10.1580/06-weme-le-042r.1" "Revista" => array:6 [ "tituloSerie" => "Wilderness Environ Med" "fecha" => "2007" "volumen" => "18" "paginaInicial" => "69" "paginaFinal" => "71" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/17447718" "web" => "Medline" ] ] ] ] 1 => array:2 [ "doi" => "10.1580/06-weme-le-042r.1" "WWW" => array:1 [ "link" => "10.1580/06-WEME-LE-042R.1" ] ] ] ] ] ] 1 => array:3 [ "identificador" => "bib2" "etiqueta" => "2" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Nodal rhythm and ventricular parasystole: an unusual electrocardiographic presentation of mad honey poisoning" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:3 [ 0 => """ F Aliyev \n \t\t\t\t\t\t\t\t """ 1 => """ C Türkoglu \n \t\t\t\t\t\t\t\t """ 2 => """ C Celiker \n \t\t\t\t\t\t\t\t """ ] ] ] ] ] "host" => array:2 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "Clin Cardiol" "fecha" => "2009" "volumen" => "32" "paginaInicial" => "52" "paginaFinal" => "54" ] ] 1 => array:1 [ "WWW" => array:1 [ "link" => "10.1002/clc.20438" ] ] ] ] ] ] 2 => array:3 [ "identificador" => "bib3" "etiqueta" => "3" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "An unusual presentation of mad honey poisoning: acute myocardial infarction" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:4 [ 0 => """ S Akinci \n \t\t\t\t\t\t\t\t """ 1 => """ U Arslan \n \t\t\t\t\t\t\t\t """ 2 => """ K Karakurt \n \t\t\t\t\t\t\t\t """ 3 => """ A Cengel \n \t\t\t\t\t\t\t\t """ ] ] ] ] ] "host" => array:2 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "Int J Cardiol" "fecha" => "2008" "volumen" => "129" "paginaInicial" => "56" "paginaFinal" => "58" ] ] 1 => array:1 [ "WWW" => array:1 [ "link" => "10.1016/j.ijcard.2007.06.129" ] ] ] ] ] ] 3 => array:3 [ "identificador" => "bib4" "etiqueta" => "4" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Mad honey poisoning" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:4 [ 0 => """ A Gunduz \n \t\t\t\t\t\t\t\t """ 1 => """ S Turedi \n \t\t\t\t\t\t\t\t """ 2 => """ H Uzun \n \t\t\t\t\t\t\t\t """ 3 => """ M Topbas \n \t\t\t\t\t\t\t\t """ ] ] ] ] ] "host" => array:2 [ 0 => array:2 [ "doi" => "10.1016/j.ajem.2006.01.022" "Revista" => array:6 [ "tituloSerie" => "Am J Emerg Med" "fecha" => "2006" "volumen" => "24" "paginaInicial" => "595" "paginaFinal" => "598" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/16938599" "web" => "Medline" ] ] ] ] 1 => array:2 [ "doi" => "10.1016/j.ajem.2006.01.022" "WWW" => array:1 [ "link" => "10.1016/j.ajem.2006.01.022" ] ] ] ] ] ] 4 => array:3 [ "identificador" => "bib5" "etiqueta" => "5" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Hypotension, bradycardia and syncope caused by honey poisoning" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:5 [ 0 => """ O Yilmaz \n \t\t\t\t\t\t\t\t """ 1 => """ M Eser \n \t\t\t\t\t\t\t\t """ 2 => """ A Sahiner \n \t\t\t\t\t\t\t\t """ 3 => """ L Altintop \n \t\t\t\t\t\t\t\t """ 4 => """ O Yesildag \n \t\t\t\t\t\t\t\t """ ] ] ] ] ] "host" => array:2 [ 0 => array:2 [ "doi" => "10.1016/j.resuscitation.2005.07.014" "Revista" => array:6 [ "tituloSerie" => "Resuscitation" "fecha" => "2006" "volumen" => "68" "paginaInicial" => "405" "paginaFinal" => "408" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/16457936" "web" => "Medline" ] ] ] ] 1 => array:2 [ "doi" => "10.1016/j.resuscitation.2005.07.014" "WWW" => array:1 [ "link" => "10.1016/j.resuscitation.2005.07.014" ] ] ] ] ] ] ] ] ] ] ] "idiomaDefecto" => "en" "url" => "/18075932/0000006600000009/v1_202212011637/S1807593222019597/v1_202212011637/en/main.assets" "Apartado" => null "PDF" => "https://static.elsevier.es/multimedia/18075932/0000006600000009/v1_202212011637/S1807593222019597/v1_202212011637/en/main.pdf?idApp=UINPBA00004N&text.app=https://www.elsevier.es/" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S1807593222019597?idApp=UINPBA00004N" ]
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